| Gene Symbol | cho-1 |
| Entrez Gene ID | 178274 |
| Full Name | High-affinity choline transporter 1 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
IVD Raw Materials
ORF » Species Summary » Caenorhabditis elegans » cho-1 cDNA ORF clone
| Gene Symbol | cho-1 |
| Entrez Gene ID | 178274 |
| Full Name | High-affinity choline transporter 1 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_070138.8 | NP_502539.1 | High-affinity choline transporter 1 |
| NM_070138.7 | NP_502539.1 | High-affinity choline transporter 1 |
| SLC5A7 | XP_001109884.1 | |
| Rattus norvegicus (Norway rat) | Slc5a7 | NP_445973.1 |
| Gallus gallus (chicken) | SLC5A7 | NP_001001763.1 |
| Danio rerio (zebrafish) | si:dkey-24h22.4 | XP_005159988.1 |
| Mus musculus (house mouse) | Slc5a7 | NP_071308.2 |
| Caenorhabditis elegans (roundworm) | cho-1 | NP_502539.1 |
| Homo sapiens (human) | SLC5A7 | NP_068587.1 |
| Canis lupus familiaris (dog) | SLC5A7 | XP_538432.3 |
| Bos taurus (cattle) | SLC5A7 | NP_001039581.1 |
| Drosophila melanogaster (fruit fly) | CG7708 | NP_650743.1 |
| Pan troglodytes (chimpanzee) | SLC5A7 | XP_001165105.1 |
| Danio rerio (zebrafish) | LOC799259 | XP_001339635.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002366 | XP_312589.3 |
| Xenopus tropicalis (tropical clawed frog) | slc5a7 | XP_002937709.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Studies to determine the impact of gene mutations on the trafficking of the Caenorhabditis elegans choline transporter orthologue revealed deficits in transporter export to axons and nerve terminals.
Title: Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization.
Although homozygous cho-1 null mutants are viable, they possess 40% less Acetylcholine than wild-type and display stress-dependent defects in motor activity.
Title: The Caenorhabditis elegans choline transporter CHO-1 sustains acetylcholine synthesis and motor function in an activity-dependent manner.
The following cho-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cho-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa342396 | |
| Clone ID Related Accession (Same CDS sequence) | NM_070138.8 , NM_070138.7 | |
| Accession Version | NM_070138.8 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | High-affinity choline transporter 1 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_070138.7. | |
1 | ATGGCCGACT TATTGGGTAT CGTGGCCATT GTGTTCTTCT ACGTGCTCAT TCTTGTCGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_502539.1 |
| CDS | 8..1738 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_070138.8 |
1 | ATGGCCGACT TATTGGGTAT CGTGGCCATT GTGTTCTTCT ACGTGCTCAT TCTTGTCGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa342396 | |
| Clone ID Related Accession (Same CDS sequence) | NM_070138.8 , NM_070138.7 | |
| Accession Version | NM_070138.7 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | High-affinity choline transporter 1 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_070138.6. COMPLETENESS: incomplete on both ends. | |
1 | ATGGCCGACT TATTGGGTAT CGTGGCCATT GTGTTCTTCT ACGTGCTCAT TCTTGTCGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_502539.1 |
| CDS | 1..1731 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_070138.7 |
1 | ATGGCCGACT TATTGGGTAT CGTGGCCATT GTGTTCTTCT ACGTGCTCAT TCTTGTCGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |