Gene Symbol | REN |
Entrez Gene ID | 403838 |
Full Name | renin |
General protein information |
|
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
ORF » Species Summary » Canis lupus familiaris » REN cDNA ORF clone
gRNAs
Gene Symbol | REN |
Entrez Gene ID | 403838 |
Full Name | renin |
General protein information |
|
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
mRNA | Protein | Name |
---|---|---|
XM_014111134.1 | XP_013966609.1 | renin isoform X1 |
NM_001003194.2 | NP_001003194.1 | renin precursor |
XM_014111135.1 | XP_013966610.1 | renin isoform X2 |
XM_005640752.2 | XP_005640809.1 | renin isoform X1 |
XM_022415287.1 | XP_022270995.1 | renin isoform X2 |
XM_005640752.1 | XP_005640809.1 | renin isoform X3 |
Homo sapiens (human) | REN | NP_000528.1 |
Mus musculus (house mouse) | Ren1 | NP_112469.1 |
Drosophila melanogaster (fruit fly) | CG10104 | NP_610961.1 |
Danio rerio (zebrafish) | ren | NP_998025.1 |
Xenopus tropicalis (tropical clawed frog) | ren | XP_002940408.2 |
Bos taurus (cattle) | REN | NP_001193438.1 |
Pan troglodytes (chimpanzee) | REN | NP_001009122.1 |
REN | NP_001028088.1 | |
Rattus norvegicus (Norway rat) | Ren | NP_036774.4 |
Canis lupus familiaris (dog) | REN | NP_001003194.1 |
Gallus gallus (chicken) | REN | XP_003642787.2 |
Role of the renin-angiotensin-aldosterone system for control of arterial blood pressure following moderate deficit in total body sodium: balance studies in freely moving dogs.
Seeliger E, Lunenburg T, Ladwig M, Reinhardt HW
Clinical and experimental pharmacology & physiology37(2)e43-51(2010 Feb)
Normotensive sodium loading in conscious dogs: regulation of renin secretion during beta-receptor blockade.
Bie P, M?lstr?m S, Wamberg S
American journal of physiology. Regulatory, integrative and comparative physiology296(2)R428-35(2009 Feb)
Cloning, characterization and site-directed mutagenesis of canine renin.
Bukhtiyarov Y, Zecher M, Panemangalore R, Wu Z, Bruno JG, Yuan J, Xu Z, Dillard LW, McGeehan GM, Harrison RK, Scott BB
Journal of biochemistry142(6)671-80(2007 Dec)
Local stress, not systemic factors, regulate gene expression of the cardiac renin-angiotensin system in vivo: a comprehensive study of all its components in the dog.
Lee YA, Liang CS, Lee MA, Lindpaintner K
Proceedings of the National Academy of Sciences of the United States of America93(20)11035-40(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
With a moderate deficit in total body sodium and total body water, the renin-angiotensin-aldosterone system is the major factor controlling arterial blood pressure.
Title: Role of the renin-angiotensin-aldosterone system for control of arterial blood pressure following moderate deficit in total body sodium: balance studies in freely moving dogs.
Normotensive sodium loading in conscious dogs: regulation of renin secretion during beta1-receptor blockade.
Title: Normotensive sodium loading in conscious dogs: regulation of renin secretion during beta-receptor blockade.
Characterization of canine renin with mutations in the substrate binding site.
Title: Cloning, characterization and site-directed mutagenesis of canine renin.
The following REN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the REN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00095 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003194.2 | |
Accession Version | NM_001003194.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-22 | |
Organism | Canis lupus familiaris(dog) | |
Product | renin precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY630442.1 and AAEX03018230.1. On May 7, 2015 this sequence version replaced NM_001003194.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY630442.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547739, SAMEA4547744 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003194.1 |
CDS | 1..1212 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31599 | |
Clone ID Related Accession (Same CDS sequence) | XM_005640752.2 , XM_005640752.1 | |
Accession Version | XM_005640752.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | renin isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006620.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005640752.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005640809.1 |
CDS | 79..1299 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31599 | |
Clone ID Related Accession (Same CDS sequence) | XM_005640752.2 , XM_005640752.1 | |
Accession Version | XM_005640752.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | renin isoform X3 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726124.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005640809.1 |
CDS | 64..1284 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe284948 | |
Clone ID Related Accession (Same CDS sequence) | XM_022415287.1 | |
Accession Version | XM_022415287.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | renin isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006620.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCCTCCA TCCGGGAAAG CCTGAAGGAG CGAGGCGTGG ATGTGGCCGG GCTTGGGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_022270995.1 |
CDS | 208..1317 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCCTCCA TCCGGGAAAG CCTGAAGGAG CGAGGCGTGG ATGTGGCCGG GCTTGGGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe45280 | |
Clone ID Related Accession (Same CDS sequence) | XM_014111134.1 | |
Accession Version | XM_014111134.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | renin isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726124.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013966609.1 |
CDS | 64..1506 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe45281 | |
Clone ID Related Accession (Same CDS sequence) | XM_014111135.1 | |
Accession Version | XM_014111135.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | renin isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726124.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013966610.1 |
CDS | 64..1497 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCAGAT GCAGAATGCC TCGCTGGGGA CTCCTGCTGG TGCTCTGGGG CTCCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Role of the renin-angiotensin-aldosterone system for control of arterial blood pressure following moderate deficit in total body sodium: balance studies in freely moving dogs. |
Normotensive sodium loading in conscious dogs: regulation of renin secretion during beta-receptor blockade. |
Cloning, characterization and site-directed mutagenesis of canine renin. |
Local stress, not systemic factors, regulate gene expression of the cardiac renin-angiotensin system in vivo: a comprehensive study of all its components in the dog. |