ALOX5 cDNA ORF clone, Canis lupus familiaris(dog)
| Gene Symbol | ALOX5 |
| Entrez Gene ID | 477753 |
| Full Name | arachidonate 5-lipoxygenase |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Canis lupus familiaris(dog) |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001205113.1 | NP_001192042.1 | arachidonate 5-lipoxygenase |
| Homo sapiens (human) | ALOX5 | NP_000689.1 |
| Oryza sativa (rice) | Os03g0738600 | NP_001051212.1 |
| Canis lupus familiaris (dog) | ALOX5 | NP_001192042.1 |
| Bos taurus (cattle) | ALOX5 | NP_001179721.1 |
| Arabidopsis thaliana (thale cress) | LOX5 | NP_188879.2 |
| Pan troglodytes (chimpanzee) | ALOX5 | XP_507763.3 |
| ALOX5 | XP_001102354.1 | |
| Mus musculus (house mouse) | Alox5 | NP_033792.1 |
| Rattus norvegicus (Norway rat) | Alox5 | NP_036954.1 |
| Gallus gallus (chicken) | ALOX5 | XP_003641560.1 |
| Xenopus tropicalis (tropical clawed frog) | alox5 | XP_004915982.1 |
| Oryza sativa (rice) | Os03g0700400 | NP_001050993.1 |
| Danio rerio (zebrafish) | alox5a | NP_001243676.1 |
| Arabidopsis thaliana (thale cress) | LOX1 | NP_175900.1 |
| Oryza sativa (rice) | Os03g0699700 | NP_001050990.1 |
| Oryza sativa (rice) | Os03g0700700 | NP_001050995.2 |
Related articles in PubMed
Cloning and antibody recognition analysis of the canine 5-lipoxygenase gene.
Loftus JP, Morgan SK, Wakshlag JJ
Veterinary immunology and immunopathology142(3-4)276-9(2011 Aug)
Expression and activity of COX-1 and 2 and 5-LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis.
Lascelles BD, King S, Roe S, Marcellin-Little DJ, Jones S
Journal of orthopaedic research : official publication of the Orthopaedic Research Society27(9)1204-8(2009 Sep)
Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export.
Flamand N, Luo M, Peters-Golden M, Brock TG
The Journal of biological chemistry284(1)306-13(2009 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
There was no significant difference in COX-1 or LOX protein in osteoarthritis hip joints
Title: Expression and activity of COX-1 and 2 and 5-LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis.
nuclear import, which is regulated by phosphorylation on Ser-523, to determine the subcellular distribution of 5-LO, which in turn regulates leukotriene biosynthesis.
Title: Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export.
The following ALOX5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALOX5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCe33788 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001205113.1 | |
| Accession Version | NM_001205113.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2031bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-22 | |
| Organism | Canis lupus familiaris(dog) | |
| Product | arachidonate 5-lipoxygenase | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from HQ657323.1. On Mar 25, 2011 this sequence version replaced XM_534950.2. ##Evidence-Data-START## Transcript exon combination :: HQ657323.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGCCGTCCT ACACGGTCAC CGTGGCCACC GGCAGCCAGT GGTTCGCTGG CACCGACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001192042.1 |
| CDS | 12..2042 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001205113.1 |
ORF Insert Sequence:
1 | ATGCCGTCCT ACACGGTCAC CGTGGCCACC GGCAGCCAGT GGTTCGCTGG CACCGACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Cloning and antibody recognition analysis of the canine 5-lipoxygenase gene. |
|
Expression and activity of COX-1 and 2 and 5-LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis. |
|
Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export. |