ORF cDNA Clones and Custom Clones » Species Summary » Danio rerio » mhc2b cDNA ORF clone

mhc2b cDNA ORF clone, Danio rerio(zebrafish)

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Summary

Gene Symbol	mhc2b
Entrez Gene ID	368615
Full Name	major histocompatibility complex class II integral membrane beta chain gene
Synonyms	MHCII,si:busm1-194e12.12,si:busm1-48c11.4,si:dz194e12.12,si:dz48c11.4,zgc:123061
General protein information	Preferred Names major histocompatibility complex class II integral membrane beta chain gene Names major histocompatibility complex class II integral membrane beta chain MHC class II beta beta chain
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007206.2	NP_001007207.2	major histocompatibility complex class II integral membrane beta chain precursor

Homologies

Danio rerio (zebrafish)	LOC100331463	XP_002667912.2
Danio rerio (zebrafish)	mhc2dbb	NP_001070245.1
Danio rerio (zebrafish)	mhc2dcb	NP_571781.1
Danio rerio (zebrafish)	si:busm1-104n07.3	XP_005167291.1
Danio rerio (zebrafish)	si:zfos-2070c2.3	XP_002663212.1
Danio rerio (zebrafish)	mhc2dab	NP_571551.2
Danio rerio (zebrafish)	wu:fd58b11	XP_005168179.1
Danio rerio (zebrafish)	si:dkey-33b17.3	XP_005165041.1
Danio rerio (zebrafish)	si:busm1-228j01.6	NP_001001595.1
Danio rerio (zebrafish)	si:busm1-194e12.12	NP_001007207.2

Bibliography

Related articles in PubMed

NOD1 deficiency impairs CD44a/Lck as well as PI3K/Akt pathway.
Hu YW, Wu XM, Ren SS, Cao L, Nie P, Chang MX
Scientific reports7(1)2979(2017 Jun)

Role of zebrafish NLRC5 in antiviral response and transcriptional regulation of MHC related genes.
Wu XM, Hu YW, Xue NN, Ren SS, Chen SN, Nie P, Chang MX
Developmental and comparative immunology6858-68(2017 Mar)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).
Yoon S, Mitra S, Wyse C, Alnabulsi A, Zou J, Weerdenburg EM, van der Sar AM, Wang D, Secombes CJ, Bird S
PloS one10(6)e0126378(2015)

Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.
Dijkstra JM, Grimholt U, Leong J, Koop BF, Hashimoto K
BMC evolutionary biology13260(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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The following mhc2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mhc2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa32763	NM_001007206.2 Latest version!	Danio rerio major histocompatibility complex class II integral membrane beta chain gene (mhc2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

mhc2b ( NM_001007206.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001007207.2 Danio rerio major histocompatibility complex class II integral membrane beta chain gene (mhc2b), mRNA.

Price & Availability↑

CloneID	ODa32763
Clone ID Related Accession (Same CDS sequence)	NM_001007206.2
Accession Version	NM_001007206.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1⁺/C-(K)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Danio rerio(zebrafish)
Product	major histocompatibility complex class II integral membrane beta chain precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC107843.1. On Dec 11, 2005 this sequence version replaced NM_001007206.1. ##Evidence-Data-START## Transcript exon combination :: BC107843.1, EH451356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTTGCCGC TAAAGTACTT GACATGTCTC ATGTTGACAG TGTCTTCATT TACTGGAGCA 
GAAAGTGCTA ATGTGTATTA CACATACCGT TGGTGCAGAT GCATCTACAG CTCCCCTGAT 
CTCAGTGATA TGGTGTATAT TGATAGCTAT TATTTTAATA AATATCTGTT CACACAGTTC 
AACAGTACTC TTGGGAAATG TGTGGGGTTT AGTGAGTATG GAATAAGAAA TGCAGAGTAC 
TGGAACAATG GAACCTTTGT GGAGCAAGAG AGAAACGAAG TGGAGAGATT CTGCAAACAT 
AATTCTCAAA TCAGGGACTC AGCTGTCATT AGCAAAGCAG TGAAGCCAAA GGTTAAGCTC 
AGCTCAGTGA CACGGGCCGG TGGCAGGCAT CCAGCCGTGC TGATGTGCAG CGCATATGAC 
TTTTATCCTC CACACATCAA AATATCCTGG CTGAGAGATG GTCAAGTGGT GACCTCAGAT 
GTGACCTCCA CTGAGGAGAT GGCTGATGGA GACTGGTATT ACCAGATCCA CTCTGAGCTG 
GAGTACAGTC CGAAATCTGG AGAAAAGATC TCTTGTGCAG TGGAGCATGC CAGCTCAACT 
AAGCCCATCA TCTATGACTG GGATCCATCT TTTTCCGAGT CTGAGAAAAA CAAACTTGTC 
ATTGGAGCCT CTGGTCTTGT GCTGGGAATC GTCTTAGCAG CTGCTGGGCT AATTTACTAC 
AAGAAGAAAT CAACAGGGAG GATCCTGGTA CCTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007207.2
CDS	29..787
Translation	MLPLKYLTCLMLTVSSFTGAESANVYYTYRWCRCIYSSPDLSDMVYIDSYYFNKYLFTQFNSTLGKCVGFSEYGIRNAEYWNNGTFVEQERNEVERFCKHNSQIRDSAVISKAVKPKVKLSSVTRAGGRHPAVLMCSAYDFYPPHIKISWLRDGQVVTSDVTSTEEMADGDWYYQIHSELEYSPKSGEKISCAVEHASSTKPIIYDWDPSFSESEKNKLVIGASGLVLGIVLAAAGLIYYKKKSTGRILVPH

Target ORF information:

RefSeq Version	NM_001007206.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio major histocompatibility complex class II integral membrane beta chain gene (mhc2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007206.2

ORF Insert Sequence:

ATGTTGCCGC TAAAGTACTT GACATGTCTC ATGTTGACAG TGTCTTCATT TACTGGAGCA 
GAAAGTGCTA ATGTGTATTA CACATACCGT TGGTGCAGAT GCATCTACAG CTCCCCTGAT 
CTCAGTGATA TGGTGTATAT TGATAGCTAT TATTTTAATA AATATCTGTT CACACAGTTC 
AACAGTACTC TTGGGAAATG TGTGGGGTTT AGTGAGTATG GAATAAGAAA TGCAGAGTAC 
TGGAACAATG GAACCTTTGT GGAGCAAGAG AGAAACGAAG TGGAGAGATT CTGCAAACAT 
AATTCTCAAA TCAGGGACTC AGCTGTCATT AGCAAAGCAG TGAAGCCAAA GGTTAAGCTC 
AGCTCAGTGA CACGGGCCGG TGGCAGGCAT CCAGCCGTGC TGATGTGCAG CGCATATGAC 
TTTTATCCTC CACACATCAA AATATCCTGG CTGAGAGATG GTCAAGTGGT GACCTCAGAT 
GTGACCTCCA CTGAGGAGAT GGCTGATGGA GACTGGTATT ACCAGATCCA CTCTGAGCTG 
GAGTACAGTC CGAAATCTGG AGAAAAGATC TCTTGTGCAG TGGAGCATGC CAGCTCAACT 
AAGCCCATCA TCTATGACTG GGATCCATCT TTTTCCGAGT CTGAGAAAAA CAAACTTGTC 
ATTGGAGCCT CTGGTCTTGT GCTGGGAATC GTCTTAGCAG CTGCTGGGCT AATTTACTAC 
AAGAAGAAAT CAACAGGGAG GATCCTGGTA CCTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NOD1 deficiency impairs CD44a/Lck as well as PI3K/Akt pathway.
Scientific reports7(1)2979(2017 Jun)
Hu YW,Wu XM,Ren SS,Cao L,Nie P,Chang MX

Role of zebrafish NLRC5 in antiviral response and transcriptional regulation of MHC related genes.
Developmental and comparative immunology6858-68(2017 Mar)
Wu XM,Hu YW,Xue NN,Ren SS,Chen SN,Nie P,Chang MX

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).
PloS one10(6)e0126378(2015)
Yoon S,Mitra S,Wyse C,Alnabulsi A,Zou J,Weerdenburg EM,van der Sar AM,Wang D,Secombes CJ,Bird S

Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.
BMC evolutionary biology13260(2013 Nov)
Dijkstra JM,Grimholt U,Leong J,Koop BF,Hashimoto K

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Expand all

mhc2b cDNA ORF clone, Danio rerio(zebrafish)

Summary

Reference Sequences (RefSeq)

Pathways from BioSystems

Homologies

Gene Ontology

Bibliography

Reference Sequences (Refseq)

Target ORF information:

Target ORF information:

ORF Insert Sequence:

PubMed

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