thap11 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Gene Symbol	thap11
Entrez Gene ID	406390
Full Name	THAP domain containing 11
Synonyms	wu:fa14e04,wu:fc33b05,zgc:65871,zgc:76876
General protein information	Preferred Names THAP domain containing 11 Names THAP domain-containing protein 11
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA Protein Name

NM_213102.1 NP_998267.1 THAP domain-containing protein 11
Pathways from BioSystems

mRNA	Protein	Name
NM_213102.1	NP_998267.1	THAP domain-containing protein 11

Homologies

Rattus norvegicus (Norway rat)	Thap11	NP_001100892.1
Pan troglodytes (chimpanzee)	THAP11	XP_511041.1
Bos taurus (cattle)	THAP11	NP_001098464.1
Mus musculus (house mouse)	Thap11	NP_067488.1
Danio rerio (zebrafish)	thap11	NP_998267.1
Homo sapiens (human)	THAP11	NP_065190.2
	THAP11	XP_001095010.1
Canis lupus familiaris (dog)	THAP11	XP_005620865.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in THAP11 cause an inborn error of cobalamin metabolism and developmental abnormalities.
Quintana AM, Yu HC, Brebner A, Pupavac M, Geiger EA, Watson A, Castro VL, Cheung W, Chen SH, Watkins D, Pastinen T, Skovby F, Appel B, Rosenblatt DS, Shaikh TH
Human molecular genetics26(15)2838-2849(2017 Aug)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

slc7a6os gene plays a critical role in defined areas of the developing CNS in zebrafish.
Benini A, Cignarella F, Calvarini L, Mantovanelli S, Giacopuzzi E, Zizioli D, Borsani G
PloS one10(3)e0119696(2015)

The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity.
Clouaire T, Roussigne M, Ecochard V, Mathe C, Amalric F, Girard JP
Proceedings of the National Academy of Sciences of the United States of America102(19)6907-12(2005 May)

Hematopoietic gene expression profile in zebrafish kidney marrow.
Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y, Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT, Chen Z
Proceedings of the National Academy of Sciences of the United States of America101(46)16240-5(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following thap11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the thap11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37763	NM_213102.1 Latest version!	Danio rerio THAP domain containing 11 (thap11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

thap11 ( NM_213102.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_998267.1 Danio rerio THAP domain containing 11 (thap11), mRNA.

Price & Availability↑

CloneID	ODa37763
Clone ID Related Accession (Same CDS sequence)	NM_213102.1
Accession Version	NM_213102.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	THAP domain-containing protein 11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC066471.1. ##Evidence-Data-START## Transcript exon combination :: BC066471.1 [ECO:0000332] ##Evidence-Data-END##

ATGCCCGGCT TCACTTGCTG CGTGCCCGGA TGCTACAACA ACTCACACCG GGACCGCGAT 
CTGCGATTCT ACACCTTTCC AAAGGATCCC ACTCAGCGAG AGATATGGCT GAAGAACATT 
TCGCGGGCCG GGGTGAGCGG CTGCTTTAGC ACTTTCCAGC CCACCACCGG TCACCGGGTC 
TGCAGCGTCC ACTTCCCCGG CGGCAGAAAG ACCTACACCA TCCGCGTCCC GACGCTTTTC 
CCTCTGCGCG GGGTGAACGA GAGACGGAGC AGACGCGGCC GGAGCAGGAA GGTTTCTGCG 
GTCGTGCCCA TCATCACCAG CGTCGTGTCC ACCGCTAACG AGACCGCTCC GCTGGAGGAG 
GACGAGGAGG AGGGGGACAT CGAAAACACC ACCGTGGTGC AGATCGGCCA GAACGGCCAG 
TACATCGCGC CCGTGGACCT CACGTCGTCC GGGGACGGCT CGTGCATCAC AGCGGTGGTG 
TCCGGCGGAG AGGAGTCCGC TGTCCACGAG TCGTGCTCCG TGGCCGATTT CGCGCTGTGC 
GGGGCGGATC ATTCGTACTC GCTCACCACC GGCACAACGT CCACGGAGCT GCTGCGAAAG 
CTGAACGAGC AGCGGGACAT AATCGCGCTG ATGGAGATCA AAATGAAGGA GATGAAGAAC 
ACCATCCGGC AGCTGCGAGT CACCGAGGCA CGGCTGCAGG ACGAGCTGCG GCAGCGCGAG 
CAGGAGCGCG AACGGCTGAT CTGCGCCAAC ACCATCATCA AGAGGAAACT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998267.1
CDS	124..897
Translation	MPGFTCCVPGCYNNSHRDRDLRFYTFPKDPTQREIWLKNISRAGVSGCFSTFQPTTGHRVCSVHFPGGRKTYTIRVPTLFPLRGVNERRSRRGRSRKVSAVVPIITSVVSTANETAPLEEDEEEGDIENTTVVQIGQNGQYIAPVDLTSSGDGSCITAVVSGGEESAVHESCSVADFALCGADHSYSLTTGTTSTELLRKLNEQRDIIALMEIKMKEMKNTIRQLRVTEARLQDELRQREQERERLICANTIIKRKL

Target ORF information:

RefSeq Version	NM_213102.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio THAP domain containing 11 (thap11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213102.1

ORF Insert Sequence:

ATGCCCGGCT TCACTTGCTG CGTGCCCGGA TGCTACAACA ACTCACACCG GGACCGCGAT 
CTGCGATTCT ACACCTTTCC AAAGGATCCC ACTCAGCGAG AGATATGGCT GAAGAACATT 
TCGCGGGCCG GGGTGAGCGG CTGCTTTAGC ACTTTCCAGC CCACCACCGG TCACCGGGTC 
TGCAGCGTCC ACTTCCCCGG CGGCAGAAAG ACCTACACCA TCCGCGTCCC GACGCTTTTC 
CCTCTGCGCG GGGTGAACGA GAGACGGAGC AGACGCGGCC GGAGCAGGAA GGTTTCTGCG 
GTCGTGCCCA TCATCACCAG CGTCGTGTCC ACCGCTAACG AGACCGCTCC GCTGGAGGAG 
GACGAGGAGG AGGGGGACAT CGAAAACACC ACCGTGGTGC AGATCGGCCA GAACGGCCAG 
TACATCGCGC CCGTGGACCT CACGTCGTCC GGGGACGGCT CGTGCATCAC AGCGGTGGTG 
TCCGGCGGAG AGGAGTCCGC TGTCCACGAG TCGTGCTCCG TGGCCGATTT CGCGCTGTGC 
GGGGCGGATC ATTCGTACTC GCTCACCACC GGCACAACGT CCACGGAGCT GCTGCGAAAG 
CTGAACGAGC AGCGGGACAT AATCGCGCTG ATGGAGATCA AAATGAAGGA GATGAAGAAC 
ACCATCCGGC AGCTGCGAGT CACCGAGGCA CGGCTGCAGG ACGAGCTGCG GCAGCGCGAG 
CAGGAGCGCG AACGGCTGAT CTGCGCCAAC ACCATCATCA AGAGGAAACT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in THAP11 cause an inborn error of cobalamin metabolism and developmental abnormalities.
Human molecular genetics26(15)2838-2849(2017 Aug)
Quintana AM,Yu HC,Brebner A,Pupavac M,Geiger EA,Watson A,Castro VL,Cheung W,Chen SH,Watkins D,Pastinen T,Skovby F,Appel B,Rosenblatt DS,Shaikh TH

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

slc7a6os gene plays a critical role in defined areas of the developing CNS in zebrafish.
PloS one10(3)e0119696(2015)
Benini A,Cignarella F,Calvarini L,Mantovanelli S,Giacopuzzi E,Zizioli D,Borsani G

The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity.
Proceedings of the National Academy of Sciences of the United States of America102(19)6907-12(2005 May)
Clouaire T,Roussigne M,Ecochard V,Mathe C,Amalric F,Girard JP

Hematopoietic gene expression profile in zebrafish kidney marrow.
Proceedings of the National Academy of Sciences of the United States of America101(46)16240-5(2004 Nov)
Song HD,Sun XJ,Deng M,Zhang GW,Zhou Y,Wu XY,Sheng Y,Chen Y,Ruan Z,Jiang CL,Fan HY,Zon LI,Kanki JP,Liu TX,Look AT,Chen Z

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thap11 cDNA ORF clone, Danio rerio(zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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