bbs1 cDNA ORF clone, Danio rerio(zebrafish)
| Gene Symbol | bbs1 |
| Entrez Gene ID | 568986 |
| Full Name | Bardet-Biedl syndrome 1 |
| Synonyms | im:7144669 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Danio rerio(zebrafish) |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001098251.1 | NP_001091721.1 | Bardet-Biedl syndrome 1 protein |
| Homo sapiens (human) | BBS1 | NP_078925.3 |
| Canis lupus familiaris (dog) | BBS1 | XP_540830.2 |
| Bos taurus (cattle) | BBS1 | XP_003588094.2 |
| Mus musculus (house mouse) | Bbs1 | NP_001028300.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007459 | XP_308406.4 |
| Pan troglodytes (chimpanzee) | BBS1 | XP_001171950.1 |
| Rattus norvegicus (Norway rat) | Bbs1 | NP_001101039.1 |
| Danio rerio (zebrafish) | bbs1 | NP_001091721.1 |
| Drosophila melanogaster (fruit fly) | BBS1 | NP_648080.1 |
| Caenorhabditis elegans (roundworm) | bbs-1 | NP_740933.1 |
| Xenopus tropicalis (tropical clawed frog) | bbs1 | NP_001116276.1 |
Related articles in PubMed
Sample Preparation and Analysis of RNASeq-based Gene Expression Data from Zebrafish.
Hostelley TL, Nesmith JE, Zaghloul NA
Journal of visualized experiments : JoVE(128)(2017 Oct)
Differential effects on ?-cell mass by disruption of Bardet-Biedl syndrome or Alstrom syndrome genes.
Lodh S, Hostelley TL, Leitch CC, O'Hare EA, Zaghloul NA
Human molecular genetics25(1)57-68(2016 Jan)
Basal body proteins regulate Notch signaling through endosomal trafficking.
Leitch CC, Lodh S, Prieto-Echag?e V, Badano JL, Zaghloul NA
Journal of cell science127(Pt 11)2407-19(2014 Jun)
Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators.
Liu YP, Tsai IC, Morleo M, Oh EC, Leitch CC, Massa F, Lee BH, Parker DS, Finley D, Zaghloul NA, Franco B, Katsanis N
The Journal of clinical investigation124(5)2059-70(2014 May)
A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish.
Kim YH, Epting D, Slanchev K, Engel C, Walz G, Kramer-Zucker A
PloS one8(9)e72549(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
loss of BBS1, BBS4, or OFD1 led to decreased NF-kappaB activity and concomitant IkappaBbeta accumulation and that these defects were ameliorated with SFN treatment.
Title: Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators.
Loss-of-function of bbs1 or bbs3 in zebrafish results in the same phenotypes as knockdown of other Bardet-Biedl syndrome genes.
Title: Genetic interaction between Bardet-Biedl syndrome genes and implications for limb patterning.
The following bbs1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the bbs1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ODa38752 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001098251.1 | |
| Accession Version | NM_001098251.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1767bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-04-22 | |
| Organism | Danio rerio(zebrafish) | |
| Product | Bardet-Biedl syndrome 1 protein | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC139697.1. On May 25, 2007 this sequence version replaced XM_692347.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC139697.1, BC162155.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCATCTG TTCCCCAGGA GTTGAAAGAC ACTTCGGTGG CAAGCTCCAA ATGGCTCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001091721.1 |
| CDS | 60..1826 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001098251.1 |
ORF Insert Sequence:
1 | ATGTCATCTG TTCCCCAGGA GTTGAAAGAC ACTTCGGTGG CAAGCTCCAA ATGGCTCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Sample Preparation and Analysis of RNASeq-based Gene Expression Data from Zebrafish. |
|
Differential effects on ?-cell mass by disruption of Bardet-Biedl syndrome or Alstrom syndrome genes. |
|
Basal body proteins regulate Notch signaling through endosomal trafficking. |
|
Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. |
|
A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish. |