Gene Symbol | dock |
Entrez Gene ID | 33262 |
Full Name | dreadlocks |
Synonyms | CG3727,DOCK,Dm0447,Dmel\CG3727,Dock,Nck,dck,doc,l(2)04723 |
General protein information |
|
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » dock cDNA ORF clone
Gene Symbol | dock |
Entrez Gene ID | 33262 |
Full Name | dreadlocks |
Synonyms | CG3727,DOCK,Dm0447,Dmel\CG3727,Dock,Nck,dck,doc,l(2)04723 |
General protein information |
|
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_164389.2 | NP_722657.1 | dreadlocks, isoform B |
NM_164390.2 | NP_722658.1 | dreadlocks, isoform C |
NM_001272916.1 | NP_001259845.1 | dreadlocks, isoform D |
NM_057628.4 | NP_476976.1 | dreadlocks, isoform A |
Pan troglodytes (chimpanzee) | NCK1 | NP_001233509.1 |
NCK1 | XP_002803036.1 | |
Canis lupus familiaris (dog) | NCK1 | XP_005634527.1 |
Rattus norvegicus (Norway rat) | Nck1 | NP_001100321.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010135 | XP_319290.3 |
Homo sapiens (human) | NCK1 | NP_006144.1 |
Xenopus tropicalis (tropical clawed frog) | nck1 | NP_001008101.1 |
Bos taurus (cattle) | NCK1 | NP_001069540.1 |
Mus musculus (house mouse) | Nck1 | NP_035008.2 |
Danio rerio (zebrafish) | nck1b | XP_005162580.1 |
Drosophila melanogaster (fruit fly) | dock | NP_001259845.1 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results demonstrate that Dock selectively enhances the PTP61Fm-mediated attenuation of InR signalling and underscores the specificity of PTPs and the importance of adaptor proteins in regulating PTP function in vivo.
Title: Differential regulation of protein tyrosine kinase signalling by Dock and the PTP61F variants.
Data indicate that Activated Cdc42 kinase Ack forms a complex with dreadlocks via its SH2 domain.
Title: Activated Cdc42 kinase regulates Dock localization in male germ cells during Drosophila spermatogenesis.
Study propose that Dock links cell adhesion in FCs and FCMs with either Scar- or Vrp1-WASp-dependent Arp2/3 activation.
Title: Dock mediates Scar- and WASp-dependent actin polymerization through interaction with cell adhesion molecules in founder cells and fusion-competent myoblasts.
Studies reveal for the first time that the adaptor protein Dock/Nck attenuates insulin signalling by recruiting PTP61F/PTP1B to its substrate, the IR.
Title: Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling.
The Nck/Dock SH2/SH3 adapter protein plays a role in photoreceptor (R cell) axon guidance and target recognition in the Drosophila visual system.It mediates between cell surface receptors and the actin cytoskeleton. Review.
Title: Dissecting Nck/Dock signaling pathways in Drosophila visual system.
The following dock gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dock cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa13397 | |
Clone ID Related Accession (Same CDS sequence) | NM_057628.4 | |
Accession Version | NM_057628.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | dreadlocks, isoform A | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_057628.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGGCGGGCA ACATGAAGCA CGGCAAATCT CAGGACGACG TCTGCTACGT GGTAGCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_476976.1 |
CDS | 1185..2417 |
Translation |
Target ORF information:
Target ORF information:
|
NM_057628.4 |
1 | ATGGCGGGCA ACATGAAGCA CGGCAAATCT CAGGACGACG TCTGCTACGT GGTAGCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFa13398 | |
Clone ID Related Accession (Same CDS sequence) | NM_164389.2 , NM_164390.2 , NM_001272916.1 | |
Accession Version | NM_164389.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | dreadlocks, isoform B | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_164389.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTTGGAAC ACCCCCAGCG GTTTGTGCGC AACATCCCCG ACTCCTCAGC CAGTTCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_722657.1 |
CDS | 654..2300 |
Translation |
Target ORF information:
Target ORF information:
|
NM_164389.2 |
1 | ATGTTGGAAC ACCCCCAGCG GTTTGTGCGC AACATCCCCG ACTCCTCAGC CAGTTCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFa13398 | |
Clone ID Related Accession (Same CDS sequence) | NM_164389.2 , NM_164390.2 , NM_001272916.1 | |
Accession Version | NM_164390.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | dreadlocks, isoform C | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_164390.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTTGGAAC ACCCCCAGCG GTTTGTGCGC AACATCCCCG ACTCCTCAGC CAGTTCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_722658.1 |
CDS | 619..2265 |
Translation |
Target ORF information:
Target ORF information:
|
NM_164390.2 |
1 | ATGTTGGAAC ACCCCCAGCG GTTTGTGCGC AACATCCCCG ACTCCTCAGC CAGTTCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFa13398 | |
Clone ID Related Accession (Same CDS sequence) | NM_164389.2 , NM_164390.2 , NM_001272916.1 | |
Accession Version | NM_001272916.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | dreadlocks, isoform D | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTTGGAAC ACCCCCAGCG GTTTGTGCGC AACATCCCCG ACTCCTCAGC CAGTTCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001259845.1 |
CDS | 771..2417 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001272916.1 |
1 | ATGTTGGAAC ACCCCCAGCG GTTTGTGCGC AACATCCCCG ACTCCTCAGC CAGTTCGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |