l(2)37Cb cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	l(2)37Cb
Entrez Gene ID	35192
Full Name	lethal (2) 37Cb
Synonyms	CG10689,Cb,Dmel\CG10689,cg10689,l(2)E104
General protein information	Preferred Names lethal (2) 37Cb Names CG10689 gene product from transcript CG10689-RA CG10689-PA l(2)37Cb-PA
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 37C1-37C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_136102.4	NP_609946.1	lethal (2) 37Cb

Pathways from BioSystems

Homologies

Homo sapiens (human)	DHX16	NP_003578.2
Rattus norvegicus (Norway rat)	Dhx16	NP_997661.1
Caenorhabditis elegans (roundworm)	mog-4	NP_497027.1
Schizosaccharomyces pombe (fission yeast)	cdc28	NP_595686.2
Neurospora crassa	NCU08928	XP_960795.1
Drosophila melanogaster (fruit fly)	l(2)37Cb	NP_609946.1
Pan troglodytes (chimpanzee)	DHX16	NP_001035839.1
	DHX16	NP_001098636.1
Mus musculus (house mouse)	Dhx16	NP_081263.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009093	XP_319843.4
Arabidopsis thaliana (thale cress)	ESP3	NP_174527.2
Canis lupus familiaris (dog)	DHX16	XP_538827.2
Danio rerio (zebrafish)	dhx16	NP_956318.1
Bos taurus (cattle)	DHX16	NP_001193139.1
Magnaporthe oryzae (rice blast fungus)	MGG_07501	XP_003711413.1
Arabidopsis thaliana (thale cress)	MEE29	NP_181077.3
Oryza sativa (rice)	Os05g0389800	NP_001055437.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following l(2)37Cb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the l(2)37Cb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa16052	NM_136102.4 Latest version!	Drosophila melanogaster lethal (2) 37Cb (l(2)37Cb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	Quote Price

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

l(2)37Cb ( NM_136102.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_609946.1 Drosophila melanogaster lethal (2) 37Cb (l(2)37Cb), mRNA.

Price & Availability↑

CloneID	OFa16052
Clone ID Related Accession (Same CDS sequence)	NM_136102.4
Accession Version	NM_136102.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2685bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	lethal (2) 37Cb
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_136102.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCGGGTA AAAACAGAAA ACGCACGGCC AGCAGCAGCA GCAGCGGTGA GGAGCCGGAC 
AGCGAGGAAG AGTCTCGCCT AAAGGACCTG CAGGAGCGCG ACGAGTTCGC CAGCCGGCTG 
AAGAAGCGGG ATGACGATCG GACGCGCAAT GTGGTTGATT CCACCGGCGG ACGAAGGGCC 
ATCGAGGAGG CCACCAAGCG ACTGAAGCTT GAGCATGAGG ATCGGGACAA GATAGTGCCT 
CACCTGCGTC TGCAGTCGCG TCGCCAGTAC CTGGAGAAGC GCAAGGATGA CAAGGTGGCC 
GAGCTGGAGG CGGACATCCT GGACGATGAG TACCTCTTCG ATGAGAGCGT CCTGACCAAA 
CGGGAGAAGG AGGAGCGCGA GTACAAGAAG CAACTGCTGA ACATCGCCAA GGAGCACGAG 
AAGGCGCGGG AACTAGAGCG CATCCAGCGT TATAATATGC CGCAGGACCT GAAAAAGGGA 
GAGCGATCTG AATACGTTGA GGTTGATGAG TTTGAGAAGC AACCCAACTC AGAGCAGAAG 
AAATGGGAGG CTGAACAGCT GGCTTCGGCG CGTTTCCATT TCGGCGCGAA AGATGCCAAG 
GCGGAGGAGG AGTATGAGCT GCTACTTGAC GATCAAATCG ATTTCATCCA AGCCCTTACC 
CTGGACGGAA GTCGAGAGAA ATCATCTAGC CGACAGCCCG AACTCACGGA GAAGGAACGC 
AAACGTTTGA CATTGGACGA AACCAGAAGA TCACTGCCCG TTTATCCGTT CAAGGAGGAT 
CTGATTGCTG CTGTAAAGGA ACATCAGGTG CTCATCATCG AAGGAGAAAC AGGCTCGGGC 
AAAACGACAC AGGTGCCGCA GTACCTCGTG GAAGCTGGTT TCACCAAGGA CAAGAAGATG 
ATCGGATGCA CGCAACCACG TCGTGTGGCC GCCATGTCGG TGGCAGCACG CGTGGCCGAG 
GAAATGGGCG TGAAGCTGGG CAACGAGGTG GGCTACAGCA TCCGTTTCGA GGACTGCACC 
TCGGATCGCA CCATTCTCAA GTACATGACG GACGGCACCC TGCATCGAGA GTTCCTTTCG 
GAACCCGACT TGGCCTCCTA CAGTGTGATG ATTATCGATG AGGCTCACGA ACGGACACTG 
CACACGGACA TTTTGTTTGG CCTGGTCAAG GATATTGCTC GCTTTAGACC AGAGTTGAAG 
CTGCTCATTT CCAGTGCCAC TCTGGATGCG GAAAAGTTCT CCGCGTTCTT CGATGATGCA 
CCCATCTTTC GGATACCTGG TCGCCGCTAT CCAGTGGACA TATTCTACAC CAAGGCTCCG 
GAAGCGGACT ACATCGACGC GTGTTGCGTT TCAGTTTTGC AGATTCATGC CACTCAACCT 
TTGGGCGACA TTCTAGTCTT CCTCACGGGT CAGGATGAGA TCGAGACTTG CCAGGAGGTT 
CTGCATGATC GCGTAAAGCG GCTGGGCTCC AAAATACGTG AGCTGATCGT TATACCCGTC 
TATGCGAATC TACCGAGTGA TATGCAGGCC AAAATCTTCG AACCCACACC GCCGAATGCC 
CGAAAAGTTA TCCTGGCCAC AAATATCGCA GAGACTTCGC TAACCATCGA CAACATCATT 
TATGTAATTG ATCCTGGGTT TGCCAAGCAG AACAATTTTA ATTCCCGCAC TGGCATGGAG 
TCGCTTATGG TGGTGCCCAT TTCCAAGGCC TCCGCCAATC AGCGAGCGGG CAGAGCGGGA 
CGAACTGCTC CGGGAAAGTG CTTCCGTCTG TATACGGCGT GGGCATACAA GCATGAACTG 
GAGGACAATA CCGTTCCGGA GATACAGCGT ATTAATCTGG GCAATGCGGT GCTCATGCTA 
AAGGCTCTGG GCATCAATGA TCTGATACAC TTCGACTTTC TGGACCCTCC GCCGCACGAG 
ACACTGGTAT TGGCTTTGGA GCAGCTATAT GCCCTGGGTG CACTTAATCA CCATGGAGAG 
TTAACCAAGC TGGGTCGACG GATGGCCGAG TTTCCCGTGG ATCCCATGAT GGGCAAGATG 
CTGCTGGCAA GCGAAAAATA CAAATGCTCC GAGGAGATGG TGACCATTGC AGCCATGCTG 
TCCGTGAATA GCGCCATTTT CTACAGGCCC AAGGACAAAA TCATTCACGC GGACACAGCC 
CGAAAAAACT TCAATCACAT GCACGGCGAC CACTTGAGCC TCCTGCAGGT CTACAATCAG 
TGGGCGGAGA CGGACTACAG CACCCAGTGG TGCTACGAGA ACTTCATCCA GTACAGATCG 
ATGAAGCGGG CTCGCGACGT GCGGGAGCAG CTGGTGGGAC TGATGCAGCG TGTCGAGATC 
GACATGGTCA GCTGCCTGCC AGAAACAGTA AACGTGCGCA AGGCAGCCAC CGCTGGTTAC 
TTTTACCATG TGGCGCGACT CTCGAAGGGC GGTCACTACA AGACCATCAA GCACAATCAG 
ACCGTGATGA TACATCCGAA CTCCTCGCTC TTTGAGGAGC TGCCGCGCTG GGTGCTCTAT 
CACGAGCTGG TGTTCACCTC CAAGGAGTAC ATGCGTCAGG TTATAGAGAT CGAGAGCAAG 
TGGTTGCTGG AGGTGGCTCC GCACTACTAC AAGGCCAAGG AGCTGGAGGA TTCGACGAAC 
AAGAAGATGC CAAAAGTCGC CGGGCGAGCC GAAATGGCGC AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_609946.1
CDS	54..2738
Translation	MSGKNRKRTASSSSSGEEPDSEEESRLKDLQERDEFASRLKKRDDDRTRNVVDSTGGRRAIEEATKRLKLEHEDRDKIVPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTKREKEEREYKKQLLNIAKEHEKARELERIQRYNMPQDLKKGERSEYVEVDEFEKQPNSEQKKWEAEQLASARFHFGAKDAKAEEEYELLLDDQIDFIQALTLDGSREKSSSRQPELTEKERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIFYTKAPEADYIDACCVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPETVNVRKAATAGYFYHVARLSKGGHYKTIKHNQTVMIHPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKELEDSTNKKMPKVAGRAEMAQ

Target ORF information:

RefSeq Version	NM_136102.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster lethal (2) 37Cb (l(2)37Cb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_136102.4

ORF Insert Sequence:

ATGTCGGGTA AAAACAGAAA ACGCACGGCC AGCAGCAGCA GCAGCGGTGA GGAGCCGGAC 
AGCGAGGAAG AGTCTCGCCT AAAGGACCTG CAGGAGCGCG ACGAGTTCGC CAGCCGGCTG 
AAGAAGCGGG ATGACGATCG GACGCGCAAT GTGGTTGATT CCACCGGCGG ACGAAGGGCC 
ATCGAGGAGG CCACCAAGCG ACTGAAGCTT GAGCATGAGG ATCGGGACAA GATAGTGCCT 
CACCTGCGTC TGCAGTCGCG TCGCCAGTAC CTGGAGAAGC GCAAGGATGA CAAGGTGGCC 
GAGCTGGAGG CGGACATCCT GGACGATGAG TACCTCTTCG ATGAGAGCGT CCTGACCAAA 
CGGGAGAAGG AGGAGCGCGA GTACAAGAAG CAACTGCTGA ACATCGCCAA GGAGCACGAG 
AAGGCGCGGG AACTAGAGCG CATCCAGCGT TATAATATGC CGCAGGACCT GAAAAAGGGA 
GAGCGATCTG AATACGTTGA GGTTGATGAG TTTGAGAAGC AACCCAACTC AGAGCAGAAG 
AAATGGGAGG CTGAACAGCT GGCTTCGGCG CGTTTCCATT TCGGCGCGAA AGATGCCAAG 
GCGGAGGAGG AGTATGAGCT GCTACTTGAC GATCAAATCG ATTTCATCCA AGCCCTTACC 
CTGGACGGAA GTCGAGAGAA ATCATCTAGC CGACAGCCCG AACTCACGGA GAAGGAACGC 
AAACGTTTGA CATTGGACGA AACCAGAAGA TCACTGCCCG TTTATCCGTT CAAGGAGGAT 
CTGATTGCTG CTGTAAAGGA ACATCAGGTG CTCATCATCG AAGGAGAAAC AGGCTCGGGC 
AAAACGACAC AGGTGCCGCA GTACCTCGTG GAAGCTGGTT TCACCAAGGA CAAGAAGATG 
ATCGGATGCA CGCAACCACG TCGTGTGGCC GCCATGTCGG TGGCAGCACG CGTGGCCGAG 
GAAATGGGCG TGAAGCTGGG CAACGAGGTG GGCTACAGCA TCCGTTTCGA GGACTGCACC 
TCGGATCGCA CCATTCTCAA GTACATGACG GACGGCACCC TGCATCGAGA GTTCCTTTCG 
GAACCCGACT TGGCCTCCTA CAGTGTGATG ATTATCGATG AGGCTCACGA ACGGACACTG 
CACACGGACA TTTTGTTTGG CCTGGTCAAG GATATTGCTC GCTTTAGACC AGAGTTGAAG 
CTGCTCATTT CCAGTGCCAC TCTGGATGCG GAAAAGTTCT CCGCGTTCTT CGATGATGCA 
CCCATCTTTC GGATACCTGG TCGCCGCTAT CCAGTGGACA TATTCTACAC CAAGGCTCCG 
GAAGCGGACT ACATCGACGC GTGTTGCGTT TCAGTTTTGC AGATTCATGC CACTCAACCT 
TTGGGCGACA TTCTAGTCTT CCTCACGGGT CAGGATGAGA TCGAGACTTG CCAGGAGGTT 
CTGCATGATC GCGTAAAGCG GCTGGGCTCC AAAATACGTG AGCTGATCGT TATACCCGTC 
TATGCGAATC TACCGAGTGA TATGCAGGCC AAAATCTTCG AACCCACACC GCCGAATGCC 
CGAAAAGTTA TCCTGGCCAC AAATATCGCA GAGACTTCGC TAACCATCGA CAACATCATT 
TATGTAATTG ATCCTGGGTT TGCCAAGCAG AACAATTTTA ATTCCCGCAC TGGCATGGAG 
TCGCTTATGG TGGTGCCCAT TTCCAAGGCC TCCGCCAATC AGCGAGCGGG CAGAGCGGGA 
CGAACTGCTC CGGGAAAGTG CTTCCGTCTG TATACGGCGT GGGCATACAA GCATGAACTG 
GAGGACAATA CCGTTCCGGA GATACAGCGT ATTAATCTGG GCAATGCGGT GCTCATGCTA 
AAGGCTCTGG GCATCAATGA TCTGATACAC TTCGACTTTC TGGACCCTCC GCCGCACGAG 
ACACTGGTAT TGGCTTTGGA GCAGCTATAT GCCCTGGGTG CACTTAATCA CCATGGAGAG 
TTAACCAAGC TGGGTCGACG GATGGCCGAG TTTCCCGTGG ATCCCATGAT GGGCAAGATG 
CTGCTGGCAA GCGAAAAATA CAAATGCTCC GAGGAGATGG TGACCATTGC AGCCATGCTG 
TCCGTGAATA GCGCCATTTT CTACAGGCCC AAGGACAAAA TCATTCACGC GGACACAGCC 
CGAAAAAACT TCAATCACAT GCACGGCGAC CACTTGAGCC TCCTGCAGGT CTACAATCAG 
TGGGCGGAGA CGGACTACAG CACCCAGTGG TGCTACGAGA ACTTCATCCA GTACAGATCG 
ATGAAGCGGG CTCGCGACGT GCGGGAGCAG CTGGTGGGAC TGATGCAGCG TGTCGAGATC 
GACATGGTCA GCTGCCTGCC AGAAACAGTA AACGTGCGCA AGGCAGCCAC CGCTGGTTAC 
TTTTACCATG TGGCGCGACT CTCGAAGGGC GGTCACTACA AGACCATCAA GCACAATCAG 
ACCGTGATGA TACATCCGAA CTCCTCGCTC TTTGAGGAGC TGCCGCGCTG GGTGCTCTAT 
CACGAGCTGG TGTTCACCTC CAAGGAGTAC ATGCGTCAGG TTATAGAGAT CGAGAGCAAG 
TGGTTGCTGG AGGTGGCTCC GCACTACTAC AAGGCCAAGG AGCTGGAGGA TTCGACGAAC 
AAGAAGATGC CAAAAGTCGC CGGGCGAGCC GAAATGGCGC AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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l(2)37Cb cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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