Gene Symbol | Ser |
Entrez Gene ID | 43275 |
Full Name | Serrate |
Synonyms | Bd,CG6127,CT18858,Dmel\CG6127,Rpw,SER,mel(3)8,ser,std |
General protein information |
|
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » Ser cDNA ORF clone
Gene Symbol | Ser |
Entrez Gene ID | 43275 |
Full Name | Serrate |
Synonyms | Bd,CG6127,CT18858,Dmel\CG6127,Rpw,SER,mel(3)8,ser,std |
General protein information |
|
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_079803.3 | NP_524527.3 | serrate, isoform A |
NM_001300629.1 | NP_001287558.1 | serrate, isoform B |
Canis lupus familiaris (dog) | JAG1 | XP_005634840.1 |
Bos taurus (cattle) | JAG1 | NP_001178107.1 |
Rattus norvegicus (Norway rat) | Jag1 | NP_062020.1 |
Gallus gallus (chicken) | JAG1 | XP_415035.4 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004154 | XP_313038.5 |
Pan troglodytes (chimpanzee) | JAG1 | XP_001169666.1 |
Drosophila melanogaster (fruit fly) | Ser | NP_524527.3 |
JAG1 | XP_001116216.2 | |
Mus musculus (house mouse) | Jag1 | NP_038850.1 |
Xenopus tropicalis (tropical clawed frog) | jag1 | XP_002931784.1 |
Homo sapiens (human) | JAG1 | NP_000205.1 |
Danio rerio (zebrafish) | jag1b | NP_571938.1 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Binding of Notch to ligands of the Delta/DLL and Serrate/JAG families from neighboring cells leads to activation of the signaling pathway and is called trans-activation
Title: Xylosylation of the Notch receptor preserves the balance between its activation by trans-Delta and inhibition by cis-ligands in Drosophila.
The Serrate-Notch-Canoe complex mediates interactions between glia and neuroepithelial cells during Drosophila optic lobe development.
Title: A Serrate-Notch-Canoe complex mediates essential interactions between glia and neuroepithelial cells during Drosophila optic lobe development.
EGF-like repeat region is responsible for both cis-inhibition and Notch inhibitory properties associated with secreted forms of Serrate.
Title: An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling.
EGFr-8 repeat may directly be involved in ligand-receptor interactions together with EGFr-11 and EGFr-12 or may be crucial for N to adopt a conformation favoring Serrate binding.
Title: A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands.
Notch activation by odorants depends on the Delta/Serrate/Lag2 ligand Delta in select olfactory receptor neurons.
Title: DSL-Notch signaling in the Drosophila brain in response to olfactory stimulation.
The following Ser gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ser cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa06301 | |
Clone ID Related Accession (Same CDS sequence) | NM_079803.3 , NM_001300629.1 | |
Accession Version | NM_079803.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4224bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | serrate, isoform A | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_079803.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTACAAAA TGTTTAGGAA ACATTTTCGG CGAAAACCAG CTACGTCGTC GTCGTTGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_524527.3 |
CDS | 435..4658 |
Translation |
Target ORF information:
Target ORF information:
|
NM_079803.3 |
1 | ATGTACAAAA TGTTTAGGAA ACATTTTCGG CGAAAACCAG CTACGTCGTC GTCGTTGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFa06301 | |
Clone ID Related Accession (Same CDS sequence) | NM_079803.3 , NM_001300629.1 | |
Accession Version | NM_001300629.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4224bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | serrate, isoform B | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTACAAAA TGTTTAGGAA ACATTTTCGG CGAAAACCAG CTACGTCGTC GTCGTTGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001287558.1 |
CDS | 707..4930 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001300629.1 |
1 | ATGTACAAAA TGTTTAGGAA ACATTTTCGG CGAAAACCAG CTACGTCGTC GTCGTTGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |