ORF cDNA Clones and Custom Clones » Species Summary » Homo sapiens » Druggable Gene Collections
Druggable Gene Collections
Identification of small molecule inhibitors of disease-related pathways is one of the most important elements of the drug development process. The first stage of small molecule inhibitor identification requires large-scale screening against proteins involved in these pathways. GenScript provides a variety of druggable gene collections, encoding disease-related pathway proteins, to help you advance your drug discovery and development research.
GenScript’s GenEZ druggable gene collections can be ordered as clone sets or as individual clones. Each GenEZ cDNA ORF in our collection is fully sequence-verified and can be custom cloned into any vector of your choice.
Click on a collection below to view all genes and gene variants in that set.
Drug interaction pathways | Number of genes |
---|---|
Druggable genome | 6098 |
Transporter | 1558 |
Kinase | 1501 |
Protease | 1142 |
Tumor suppressor | 1124 |
G protein coupled receptor | 922 |
Serine threonine kinase | 881 |
Cell surface | 808 |
Ion channel | 616 |
Transcription factor binding | 540 |
DNA repair | 528 |
Histone modification | 455 |
Drug resistance | 422 |
Clinically actionable | 398 |
Tyrosine kinase | 360 |
Transcription factor complex | 326 |
External side of plasma membrane | 292 |
Protein phosphatase | 288 |
Neutral zinc metallopeptidase | 225 |
Protease inhibitor | 201 |
Phospholipase | 183 |
Growth factor | 173 |
Hormone activity | 135 |
ABC transporter | 134 |
B30_2 SPRY domain | 89 |
Nuclear hormone receptor | 77 |
RNA directed DNA polymerase | 69 |
Lipid kinase | 67 |
Methyl transferase | 62 |
Cytochrome P450 | 57 |
Short chain dehydrogenase reductase | 53 |
Exchanger | 46 |
Drug metabolism | 45 |
Lipase | 45 |
Fibrinogen | 32 |
Thioredoxin | 30 |
Phosphatidylinositol 3 kinase | 24 |
Myotubularin related protein phosphatase | 16 |
PTEN family | 7 |
DNA directed RNA polymerase | 6 |