Gene Symbol | SOCS3 |
Entrez Gene ID | 395299 |
Full Name | suppressor of cytokine signaling 3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Gallus gallus(chicken) |
ORF » Species Summary » Gallus gallus » SOCS3 cDNA ORF clone
gRNAs
Gene Symbol | SOCS3 |
Entrez Gene ID | 395299 |
Full Name | suppressor of cytokine signaling 3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Gallus gallus(chicken) |
mRNA | Protein | Name |
---|---|---|
NM_204600.1 | NP_989931.1 | suppressor of cytokine signaling 3 |
Bos taurus (cattle) | SOCS3 | NP_776891.1 |
Mus musculus (house mouse) | Socs3 | NP_031733.1 |
Danio rerio (zebrafish) | socs3a | NP_956244.1 |
Xenopus tropicalis (tropical clawed frog) | socs3 | NP_001005696.1 |
Canis lupus familiaris (dog) | SOCS3 | NP_001026801.1 |
Rattus norvegicus (Norway rat) | Socs3 | NP_446017.1 |
Pan troglodytes (chimpanzee) | SOCS3 | XP_001157032.1 |
Homo sapiens (human) | SOCS3 | NP_003946.3 |
SOCS3 | XP_001106015.2 | |
Gallus gallus (chicken) | SOCS3 | NP_989931.1 |
Danio rerio (zebrafish) | socs3b | NP_998469.1 |
Effect of chicken leptin recptor short hairpin RNA on expression of JAK2, STAT3, SOCS3 and CPT1 genes in chicken preadipocytes.
Ban Q, Hui W, Cheng F, Liu D, Liu X
Animal science journal = Nihon chikusan Gakkaiho88(3)559-564(2017 Mar)
SOCS3 promotes inflammation and apoptosis via inhibiting JAK2/STAT3 signaling pathway in 3T3-L1 adipocyte.
Liu Z, Gan L, Zhou Z, Jin W, Sun C
Immunobiology220(8)947-53(2015 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
It is a gene related to signal transduction.
Title: Effect of chicken leptin recptor short hairpin RNA on expression of JAK2, STAT3, SOCS3 and CPT1 genes in chicken preadipocytes.
these results inferred that SOCS3 promotes adipocyte apoptosis by both aggravating inflammation and inhibiting the activity of JAK2/STAT3 signaling pathway.
Title: SOCS3 promotes inflammation and apoptosis via inhibiting JAK2/STAT3 signaling pathway in 3T3-L1 adipocyte.
The following SOCS3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SOCS3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OGa23756 | |
Clone ID Related Accession (Same CDS sequence) | NM_204600.1 | |
Accession Version | NM_204600.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-11-10 | |
Organism | Gallus gallus(chicken) | |
Product | suppressor of cytokine signaling 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF424806.1. Sequence Note: This sequence has been modified as follows: removed 32 bp suspected to be vector contamination from the 3' end. ##Evidence-Data-START## Transcript exon combination :: AF424806.1, BQ484596.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGGTCACCC ACAGCAAGTT CCCCGCCGCC GGGATGAGCC GCCCCCTGGA CACCAGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_989931.1 |
CDS | 142..771 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGTCACCC ACAGCAAGTT CCCCGCCGCC GGGATGAGCC GCCCCCTGGA CACCAGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Effect of chicken leptin recptor short hairpin RNA on expression of JAK2, STAT3, SOCS3 and CPT1 genes in chicken preadipocytes. |
SOCS3 promotes inflammation and apoptosis via inhibiting JAK2/STAT3 signaling pathway in 3T3-L1 adipocyte. |