IGF1R cDNA ORF clone, Gallus gallus(chicken)
| Gene Symbol | IGF1R |
| Entrez Gene ID | 395889 |
| Full Name | insulin like growth factor 1 receptor |
| Synonyms | IGF-1R |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Gallus gallus(chicken) |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_205032.1 | NP_990363.1 | insulin-like growth factor 1 receptor precursor |
| Pan troglodytes (chimpanzee) | IGF1R | XP_510613.2 |
| Canis lupus familiaris (dog) | IGF1R | XP_545828.2 |
| Mus musculus (house mouse) | Igf1r | NP_034643.2 |
| Gallus gallus (chicken) | IGF1R | NP_990363.1 |
| Bos taurus (cattle) | IGF1R | NP_001231541.1 |
| Danio rerio (zebrafish) | igf1ra | NP_694500.1 |
| Caenorhabditis elegans (roundworm) | daf-2 | NP_497650.4 |
| Homo sapiens (human) | IGF1R | NP_000866.1 |
| Rattus norvegicus (Norway rat) | Igf1r | NP_434694.1 |
| Danio rerio (zebrafish) | igf1rb | NP_694501.1 |
| Anopheles gambiae (African malaria mosquito) | INR | XP_320130.3 |
| Xenopus tropicalis (tropical clawed frog) | igf1r | XP_002933351.1 |
| IGF1R | XP_001100407.1 | |
| Drosophila melanogaster (fruit fly) | InR | NP_001138093.1 |
Related articles in PubMed
Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens.
Jin S, Chen S, Li H, Lu Y, Xu G, Yang N
Molecular biology reports41(6)3973-9(2014 Jun)
?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation.
Basu S, Rajakaruna S, De Arcangelis A, Zhang L, Georges-Labouesse E, Menko AS
The Journal of biological chemistry289(7)3842-55(2014 Feb)
Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.
Basu S, Rajakaruna S, Menko AS
The Journal of biological chemistry287(11)8384-97(2012 Mar)
Insulin, insulin-like growth factor-1, insulin receptor, and insulin-like growth factor-1 receptor expression in the chick eye and their regulation with imposed myopic or hyperopic defocus.
Penha AM, Schaeffel F, Feldkaemper M
Molecular vision171436-48(2011)
Polymorphisms of the IGF1R gene and their genetic effects on chicken early growth and carcass traits.
Lei M, Peng X, Zhou M, Luo C, Nie Q, Zhang X
BMC genetics970(2008 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rs14011780 of IGF1R was strongly associated with body weight (BW), body weight gain and FCR (P < 0.05)
Title: Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens.
alpha6 integrin is an essential upstream regulator of the IGF-1R survival pathway that regulates the activity level of caspase-3 for it to signal differentiation initiation of lens epithelial cells.
Title: ?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation.
the IGF-1R/NFkappaB cell survival signal is a crucial regulator of the level of caspase-3 activation for its non-apoptotic function in signaling cell differentiation.
Title: Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.
The differential regulation of insulin receptor and insulin-like growth factor-1 receptor in the the retinal pigment epithelium (RPE), choroid, and fibrous sclera is consistent with their involvement in a signaling cascade for emmetropization.
Title: Insulin, insulin-like growth factor-1, insulin receptor, and insulin-like growth factor-1 receptor expression in the chick eye and their regulation with imposed myopic or hyperopic defocus.
6 SNPs in the IGF1R gene are associated with chicken early growth and carcass traits.
Title: Polymorphisms of the IGF1R gene and their genetic effects on chicken early growth and carcass traits.
The following IGF1R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IGF1R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OGa00381 | |
| Clone ID Related Accession (Same CDS sequence) | NM_205032.1 | |
| Accession Version | NM_205032.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4092bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ® Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-11-06 | |
| Organism | Gallus gallus(chicken) | |
| Product | insulin-like growth factor 1 receptor precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ223164.1. ##Evidence-Data-START## Transcript exon combination :: AJ223164.1 [ECO:0000332] ##Evidence-Data-END## | |
1 | ATGAAGTCTG GCGCTGGAGG AGGGACCCTC GCCGTCTTCT GCGGGTTGCT GCTCGCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_990363.1 |
| CDS | 146..4237 |
| Misc Feature(1) | 296..628 |
| Misc Feature(2) | 668..1135 |
| Misc Feature(3) | 833..976 |
| Misc Feature(4) | 1196..1537 |
| Misc Feature(5) | 1628..1960 |
| Misc Feature(6) | order(1925..1930,1934..1939) |
| Misc Feature(7) | 1973..>2104 |
| Misc Feature(8) | 2648..2917 |
| Misc Feature(9) | order(2882..2887,2891..2896) |
| Misc Feature(10) | 3122..3952 |
| Misc Feature(11) | 3143..3946 |
| Misc Feature(12) | order(3161..3163,3167..3175,3185..3187,3239..3241,3245..3247,3386..3388,3392..3394,3404..3406,3551..3553,3563..3568,3572..3574,3605..3607,3656..3664,3668..3673,3698..3700,3704..3706,3800..3802) |
| Misc Feature(13) | order(3161..3163,3167..3175,3185..3187,3239..3241,3245..3247,3386..3388,3392..3394,3404..3406,3566..3568,3572..3574,3605..3607) |
| Misc Feature(14) | order(3551..3553,3563..3565,3656..3664,3668..3673,3698..3700,3704..3706,3800..3802) |
| Misc Feature(15) | 3602..3679 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_205032.1 |
ORF Insert Sequence:
1 | ATGAAGTCTG GCGCTGGAGG AGGGACCCTC GCCGTCTTCT GCGGGTTGCT GCTCGCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens. |
|
?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation. |
|
Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation. |
|
Insulin, insulin-like growth factor-1, insulin receptor, and insulin-like growth factor-1 receptor expression in the chick eye and their regulation with imposed myopic or hyperopic defocus. |
|
Polymorphisms of the IGF1R gene and their genetic effects on chicken early growth and carcass traits. |