PARP1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Gene Symbol	PARP1
Entrez Gene ID	396199
Full Name	poly (ADP-ribose) polymerase 1
Synonyms	ADPRT,ARTD1,PARP-1
General protein information	Preferred Names poly (ADP-ribose) polymerase 1 Names poly [ADP-ribose] polymerase 1 ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase diphtheria toxin-like 1 ADPRT 1 NAD(+) ADP-ribosyltransferase 1 poly (ADP-ribose) polymerase family, member 1 poly(ADP-ribose) polymerase poly[ADP-ribose] synthase 1 poly[ADP-ribose] synthetase 1
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA Protein Name

NM_205263.2 NP_990594.2 poly [ADP-ribose] polymerase 1
Pathways from BioSystems

mRNA	Protein	Name
NM_205263.2	NP_990594.2	poly [ADP-ribose] polymerase 1

Homologies

Drosophila melanogaster (fruit fly)	Parp	NP_001104452.1
Arabidopsis thaliana (thale cress)	PARP1	NP_850165.1
Oryza sativa (rice)	Os07g0413700	NP_001059453.1
Homo sapiens (human)	PARP1	NP_001609.2
Pan troglodytes (chimpanzee)	PARP1	XP_003949754.1
Canis lupus familiaris (dog)	PARP1	XP_547506.3
Bos taurus (cattle)	PARP1	NP_777176.1
	PARP1	XP_001090984.1
Gallus gallus (chicken)	PARP1	NP_990594.1
Xenopus tropicalis (tropical clawed frog)	parp1	XP_002941174.2
Danio rerio (zebrafish)	parp1	NP_001038407.1
Caenorhabditis elegans (roundworm)	pme-1	NP_491072.1
Mus musculus (house mouse)	Parp1	NP_031441.2
Rattus norvegicus (Norway rat)	Parp1	NP_037195.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003230	XP_312938.4

Gene Ontology
Bibliography

Related articles in PubMed

Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP).
Diani-Moore S, Zhang S, Ram P, Rifkind AB
The Journal of biological chemistry288(30)21514-25(2013 Jul)

Poly(ADP-ribose) polymerase 1 promotes transcriptional repression of integrated retroviruses.
Bueno MT, Reyes D, Valdes L, Saheba A, Urias E, Mendoza C, Fregoso OI, Llano M
Journal of virology87(5)2496-507(2013 Mar)

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase.
Fisher AE, Hochegger H, Takeda S, Caldecott KW
Molecular and cellular biology27(15)5597-605(2007 Aug)

RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.
Saberi A, Hochegger H, Szuts D, Lan L, Yasui A, Sale JE, Taniguchi Y, Murakawa Y, Zeng W, Yokomori K, Helleday T, Teraoka H, Arakawa H, Buerstedde JM, Takeda S
Molecular and cellular biology27(7)2562-71(2007 Apr)

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.
Yu M, Schreek S, Cerni C, Schamberger C, Lesniewicz K, Poreba E, Vervoorts J, Walsemann G, Gr?tzinger J, Kremmer E, Mehraein Y, Mertsching J, Kraft R, Austen M, L?scher-Firzlaff J, L?scher B
Oncogene24(12)1982-93(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that aryl hydrocarbon receptor (AHR) enhances phosphoenolpyruvate carboxykinase (PEPCK) ADP-ribosylation through TiPARP TiPARP (TCDD-inducible poly(ADP-ribose) polymerase).
Title: Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP).

data indicate a novel role of PARP-1 in the transcriptional repression of integrated retroviruses
Title: Poly(ADP-ribose) polymerase 1 promotes transcriptional repression of integrated retroviruses.

PARG is identified as a novel and critical component of single-strand break repair that accelerates this process in concert with PARP-1.
Title: Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase.

Higher-eukaryotic cells separately employ PARP1 and Rad18 to suppress the toxic effects of NHEJ during the HR reaction at stalled replication forks.
Title: RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.

Results show that the 40 kDa carboxy terminus of poly(ADP-ribose) polymerase-1 forms a competent catalytic dimer in the absence of DNA, and that its automodification reaction is intermolecular.
Title: The 40 kDa carboxy-terminal domain of poly(ADP-ribose) polymerase-1 forms catalytically competent homo- and heterodimers in the absence of DNA.

The following PARP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PARP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa28412	NM_205263.2 Latest version!	Gallus gallus poly(ADP-ribose) polymerase 1 (PARP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PARP1 ( NM_205263.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990594.2 Gallus gallus poly(ADP-ribose) polymerase 1 (PARP1), mRNA.

Price & Availability↑

CloneID	OGa28412
Clone ID Related Accession (Same CDS sequence)	NM_205263.2
Accession Version	NM_205263.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3036bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-02
Organism	Gallus gallus(chicken)
Product	poly [ADP-ribose] polymerase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000005.1. On Mar 5, 2015 this sequence version replaced NM_205263.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: X52690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201358, SAMEA2201359 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGA CGGGGGACAA GCCGTACCGC GCGGAGTACG CCAAGAGCGG GCGGGCGTCG 
TGCAAGAAGT GCGGCGAGAG CATCGCCAAG GACTCGCTGC GCCTGGCCCT CATGGTGCAG 
TCGCCCATGT TCGATGGCAA AGTCCCTCAC TGGCACCACT ACAGCTGCTT CTGGAAGCGG 
GCGCGGATCG TGTCCCACAC AGACATCGAT GGCTTCCCTG AGCTCCGCTG GGAGGACCAG 
GAGAAAATCA AGAAGGCTAT TGAAACCGGA GGCCCTGCAG GAGGAAAAGG GGGGGACCAG 
GAAGGAGGTG GCAAGGCTGA GAAGAGCCTA ACTGACTTTG CTGCAGAGTA TGCCAAGTCT 
AACAGGAGTA CTTGCAAAGG CTGTGAGCAG AAAATAGAAA AGGGCCAGAT TCGGATTTCC 
AAGAAGATGG TGCATCCTGA GAAACCACAG CTGGGGATGA TCGATAACTG GTACCACCCG 
GACTGCTTCG TCAGCCGCCG GGCAGAGCTG GGCTTCCTCC CAGCATATGG GGCCACACAG 
CTCCTGGGTT TCAGCATCTT GAAAGCTGAA GATAAAGAAA CTCTGAAGAA ACAGCTACCA 
GCTACTAAGA CTGAAGGAAA GAGAAAAGGA GAAGAGGTAG ATGGAAATGT GGTTGCAAAA 
AAGAAATCAA GAAAAGAAAA AGAAAAAGAA TCAAAGCAGG AAAAACAGCT GAAGGAGCAG 
ACAGAGCTGA TCTGGGGCAT CAAGGATGAG CTGAGGAAGG TCTGCTCCAC GAATGACCTG 
AAAGAGCTGC TGATCGCCAA CAAGCAGGAG GTGCCTTCAG GGGAGAATGC AATCTTGGAC 
AGAGTGGCAG ACGGGATGGC GTTTGGAGCT CTGCTTCCTT GTGAGGAGTG TAAAGGGCAG 
TTTGTGTTCA AGAGCGATGC ATACTACTGC TCAGGGGACA TTACTGCCTG GACTAAGTGT 
GTGGCTAAAA CACAGACTCC CAATAGGAAA GACTGGGTAA TCCCGAAGGA ATTTCGTGAG 
ATTCCTTATC TCAAAAAATT TAAGTGTAAG AAGCAGGATA GGATATTCCC TCCTGAGGCT 
GCAACTGTGA ACTCTGCACC GCCTCCATCT GCATCCGCTC CATTGACAGA GACTGTCACT 
GCACCCCAAG AGAAACCACT GACCAACATG AAGATCCTGA CTCTTGGAAA GCTGTCCAAG 
AACAAGGAGG AAGTGAAGAA TATTGTGGAG GAGCTGGGAG GAAAGATGAC AACAACAGCT 
AACAAGGCCA CCCTGTGCAT CAGCACACAA AAGGAGGTGG AGAAAATGAG CAAGAAGATG 
GAAGAAGTGA AGGATGCCAA AGTTCGTGTG GTCTCAGAGG AGTTTCTTAA GGATGTGAAA 
TCTTCCAGCA AGGGCTTTCA GGAGCTTCTC TCTCTCCATG CAATTTCACC TTGGGGTGCA 
GAGGTGAAAA CGGAGCACCA GGAGGTGGCG GTGGATGGGA AGTGCAGCAA GCCTGCAAAT 
ATGAAGAGTG CTGGGAAGGT CAAAGAAGAA CAAGGACCTA GCAAGTCTGA GAAGAAAATG 
AAGCTAACAG TTAAAGGTGG AGCAGCAGTA GATCCTGATT CCGGCTTGGA GGATTCTGCT 
CATGTCTTTG AAAAAGGTGG GAAGATTTTC AGTGCAACTC TTGGCCTAGT GGATATTGTG 
AAAGGAACAA ATTCCTATTA CAAACTGCAG CTGCTGGAGG ATGACAGAGA GAGCAGGTAC 
TGGGTGTTCA GATCCTGGGG TCGTGTGGGC ACTGTCATTG GGAGTAACAA GCTGGAGCAG 
ATGCCATCAA AAGAAGATGC TGTTGAACAC TTCCTAAATT TGTACGAAGA GAAAACTGGC 
AATTCTTGGC ATTCAAAGAA CTTCACTAAA TATCCCAAAA AATTCTACCC ACTGGAAATA 
GATTATGGAC AGGATGAAGA AGCTGTCAGG AAACTGACAG TGAGTGCTGG GACTAAATCG 
AAGCTTGCTA AGCCAATCCA AGACCTTATT AAGATGATTT TTGATGTGGA GAGCATGAAG 
AAAGCCATGG TGGAATTTGA GATTGACCTG CAGAAGATGC CACTGGGGAA ACTGAGCAAG 
CGACAGATCC AAAGTGCATA CTCCATCCTT AACGAGGTTC AGCAGGCGGT TTCTGACGGT 
GGTTCTGAAT CCCAGATCTT GGACCTCTCA AACCGCTTCT ATACTCTGAT CCCTCATGAC 
TTTGGGATGA AGAAACCACC TCTTCTCAGT AACTTGGAAT ACATTCAGGC TAAAGTGCAG 
ATGTTGGACA ACTTGCTCGA TATTGAGGTT GCTTACAGTC TTCTCAGAGG TGGAAATGAA 
GATGGAGACA AAGACCCAAT TGATATCAAT TATGAAAAGC TCCGAACTGA TATTAAGGTG 
GTTGACAAAG ATTCAGAAGA AGCCAAGATT ATTAAACAAT ACGTGAAAAA TACTCATGCT 
GCTACTCACA ATGCATATGA CCTCAAAGTT GTGGAAATCT TCAGGATTGA ACGTGAAGGA 
GAGAGTCAGC GTTACAAGCC ATTTAAGCAG CTTCATAATC GCCAGCTGCT GTGGCACGGT 
TCCCGCACCA CCAACTTCGC TGGTATCCTC TCACAGGGTC TCCGGATAGC TCCCCCTGAA 
GCTCCTGTGA CCGGCTACAT GTTTGGGAAG GGCATCTACT TTGCAGATAT GGTTTCCAAG 
AGTGCCAACT ACTGTCACAC ATCTCAAGCT GATCCAATTG GGTTAATACT ACTGGGAGAA 
GTTGCCCTCG GAAATATGTA TGAGCTAAAG AATGCTTCTC ACATAACAAA ATTGCCCAAG 
GGAAAACATA GTGTGAAAGG CTTGGGCAAA ACTGCACCTG ATCCCACAGC CACTACAACC 
CTTGATGGTG TAGAAGTTCC CTTAGGGAAT GGGATCTCAA CAGGAATTAA TGATACTTGT 
CTGCTGTACA ATGAATATAT TGTGTATGAT GTTGCTCAGG TAAATCTGAA GTACCTGCTG 
AAACTGAAAT TCAACTATAA GACATCACTC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990594.2
CDS	90..3125
Translation	MAETGDKPYRAEYAKSGRASCKKCGESIAKDSLRLALMVQSPMFDGKVPHWHHYSCFWKRARIVSHTDIDGFPELRWEDQEKIKKAIETGGPAGGKGGDQEGGGKAEKSLTDFAAEYAKSNRSTCKGCEQKIEKGQIRISKKMVHPEKPQLGMIDNWYHPDCFVSRRAELGFLPAYGATQLLGFSILKAEDKETLKKQLPATKTEGKRKGEEVDGNVVAKKKSRKEKEKESKQEKQLKEQTELIWGIKDELRKVCSTNDLKELLIANKQEVPSGENAILDRVADGMAFGALLPCEECKGQFVFKSDAYYCSGDITAWTKCVAKTQTPNRKDWVIPKEFREIPYLKKFKCKKQDRIFPPEAATVNSAPPPSASAPLTETVTAPQEKPLTNMKILTLGKLSKNKEEVKNIVEELGGKMTTTANKATLCISTQKEVEKMSKKMEEVKDAKVRVVSEEFLKDVKSSSKGFQELLSLHAISPWGAEVKTEHQEVAVDGKCSKPANMKSAGKVKEEQGPSKSEKKMKLTVKGGAAVDPDSGLEDSAHVFEKGGKIFSATLGLVDIVKGTNSYYKLQLLEDDRESRYWVFRSWGRVGTVIGSNKLEQMPSKEDAVEHFLNLYEEKTGNSWHSKNFTKYPKKFYPLEIDYGQDEEAVRKLTVSAGTKSKLAKPIQDLIKMIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSILNEVQQAVSDGGSESQILDLSNRFYTLIPHDFGMKKPPLLSNLEYIQAKVQMLDNLLDIEVAYSLLRGGNEDGDKDPIDINYEKLRTDIKVVDKDSEEAKIIKQYVKNTHAATHNAYDLKVVEIFRIEREGESQRYKPFKQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQADPIGLILLGEVALGNMYELKNASHITKLPKGKHSVKGLGKTAPDPTATTTLDGVEVPLGNGISTGINDTCLLYNEYIVYDVAQVNLKYLLKLKFNYKTSLW

Target ORF information:

RefSeq Version	NM_205263.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus poly(ADP-ribose) polymerase 1 (PARP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205263.2

ORF Insert Sequence:

ATGGCGGAGA CGGGGGACAA GCCGTACCGC GCGGAGTACG CCAAGAGCGG GCGGGCGTCG 
TGCAAGAAGT GCGGCGAGAG CATCGCCAAG GACTCGCTGC GCCTGGCCCT CATGGTGCAG 
TCGCCCATGT TCGATGGCAA AGTCCCTCAC TGGCACCACT ACAGCTGCTT CTGGAAGCGG 
GCGCGGATCG TGTCCCACAC AGACATCGAT GGCTTCCCTG AGCTCCGCTG GGAGGACCAG 
GAGAAAATCA AGAAGGCTAT TGAAACCGGA GGCCCTGCAG GAGGAAAAGG GGGGGACCAG 
GAAGGAGGTG GCAAGGCTGA GAAGAGCCTA ACTGACTTTG CTGCAGAGTA TGCCAAGTCT 
AACAGGAGTA CTTGCAAAGG CTGTGAGCAG AAAATAGAAA AGGGCCAGAT TCGGATTTCC 
AAGAAGATGG TGCATCCTGA GAAACCACAG CTGGGGATGA TCGATAACTG GTACCACCCG 
GACTGCTTCG TCAGCCGCCG GGCAGAGCTG GGCTTCCTCC CAGCATATGG GGCCACACAG 
CTCCTGGGTT TCAGCATCTT GAAAGCTGAA GATAAAGAAA CTCTGAAGAA ACAGCTACCA 
GCTACTAAGA CTGAAGGAAA GAGAAAAGGA GAAGAGGTAG ATGGAAATGT GGTTGCAAAA 
AAGAAATCAA GAAAAGAAAA AGAAAAAGAA TCAAAGCAGG AAAAACAGCT GAAGGAGCAG 
ACAGAGCTGA TCTGGGGCAT CAAGGATGAG CTGAGGAAGG TCTGCTCCAC GAATGACCTG 
AAAGAGCTGC TGATCGCCAA CAAGCAGGAG GTGCCTTCAG GGGAGAATGC AATCTTGGAC 
AGAGTGGCAG ACGGGATGGC GTTTGGAGCT CTGCTTCCTT GTGAGGAGTG TAAAGGGCAG 
TTTGTGTTCA AGAGCGATGC ATACTACTGC TCAGGGGACA TTACTGCCTG GACTAAGTGT 
GTGGCTAAAA CACAGACTCC CAATAGGAAA GACTGGGTAA TCCCGAAGGA ATTTCGTGAG 
ATTCCTTATC TCAAAAAATT TAAGTGTAAG AAGCAGGATA GGATATTCCC TCCTGAGGCT 
GCAACTGTGA ACTCTGCACC GCCTCCATCT GCATCCGCTC CATTGACAGA GACTGTCACT 
GCACCCCAAG AGAAACCACT GACCAACATG AAGATCCTGA CTCTTGGAAA GCTGTCCAAG 
AACAAGGAGG AAGTGAAGAA TATTGTGGAG GAGCTGGGAG GAAAGATGAC AACAACAGCT 
AACAAGGCCA CCCTGTGCAT CAGCACACAA AAGGAGGTGG AGAAAATGAG CAAGAAGATG 
GAAGAAGTGA AGGATGCCAA AGTTCGTGTG GTCTCAGAGG AGTTTCTTAA GGATGTGAAA 
TCTTCCAGCA AGGGCTTTCA GGAGCTTCTC TCTCTCCATG CAATTTCACC TTGGGGTGCA 
GAGGTGAAAA CGGAGCACCA GGAGGTGGCG GTGGATGGGA AGTGCAGCAA GCCTGCAAAT 
ATGAAGAGTG CTGGGAAGGT CAAAGAAGAA CAAGGACCTA GCAAGTCTGA GAAGAAAATG 
AAGCTAACAG TTAAAGGTGG AGCAGCAGTA GATCCTGATT CCGGCTTGGA GGATTCTGCT 
CATGTCTTTG AAAAAGGTGG GAAGATTTTC AGTGCAACTC TTGGCCTAGT GGATATTGTG 
AAAGGAACAA ATTCCTATTA CAAACTGCAG CTGCTGGAGG ATGACAGAGA GAGCAGGTAC 
TGGGTGTTCA GATCCTGGGG TCGTGTGGGC ACTGTCATTG GGAGTAACAA GCTGGAGCAG 
ATGCCATCAA AAGAAGATGC TGTTGAACAC TTCCTAAATT TGTACGAAGA GAAAACTGGC 
AATTCTTGGC ATTCAAAGAA CTTCACTAAA TATCCCAAAA AATTCTACCC ACTGGAAATA 
GATTATGGAC AGGATGAAGA AGCTGTCAGG AAACTGACAG TGAGTGCTGG GACTAAATCG 
AAGCTTGCTA AGCCAATCCA AGACCTTATT AAGATGATTT TTGATGTGGA GAGCATGAAG 
AAAGCCATGG TGGAATTTGA GATTGACCTG CAGAAGATGC CACTGGGGAA ACTGAGCAAG 
CGACAGATCC AAAGTGCATA CTCCATCCTT AACGAGGTTC AGCAGGCGGT TTCTGACGGT 
GGTTCTGAAT CCCAGATCTT GGACCTCTCA AACCGCTTCT ATACTCTGAT CCCTCATGAC 
TTTGGGATGA AGAAACCACC TCTTCTCAGT AACTTGGAAT ACATTCAGGC TAAAGTGCAG 
ATGTTGGACA ACTTGCTCGA TATTGAGGTT GCTTACAGTC TTCTCAGAGG TGGAAATGAA 
GATGGAGACA AAGACCCAAT TGATATCAAT TATGAAAAGC TCCGAACTGA TATTAAGGTG 
GTTGACAAAG ATTCAGAAGA AGCCAAGATT ATTAAACAAT ACGTGAAAAA TACTCATGCT 
GCTACTCACA ATGCATATGA CCTCAAAGTT GTGGAAATCT TCAGGATTGA ACGTGAAGGA 
GAGAGTCAGC GTTACAAGCC ATTTAAGCAG CTTCATAATC GCCAGCTGCT GTGGCACGGT 
TCCCGCACCA CCAACTTCGC TGGTATCCTC TCACAGGGTC TCCGGATAGC TCCCCCTGAA 
GCTCCTGTGA CCGGCTACAT GTTTGGGAAG GGCATCTACT TTGCAGATAT GGTTTCCAAG 
AGTGCCAACT ACTGTCACAC ATCTCAAGCT GATCCAATTG GGTTAATACT ACTGGGAGAA 
GTTGCCCTCG GAAATATGTA TGAGCTAAAG AATGCTTCTC ACATAACAAA ATTGCCCAAG 
GGAAAACATA GTGTGAAAGG CTTGGGCAAA ACTGCACCTG ATCCCACAGC CACTACAACC 
CTTGATGGTG TAGAAGTTCC CTTAGGGAAT GGGATCTCAA CAGGAATTAA TGATACTTGT 
CTGCTGTACA ATGAATATAT TGTGTATGAT GTTGCTCAGG TAAATCTGAA GTACCTGCTG 
AAACTGAAAT TCAACTATAA GACATCACTC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP).
The Journal of biological chemistry288(30)21514-25(2013 Jul)
Diani-Moore S,Zhang S,Ram P,Rifkind AB

Poly(ADP-ribose) polymerase 1 promotes transcriptional repression of integrated retroviruses.
Journal of virology87(5)2496-507(2013 Mar)
Bueno MT,Reyes D,Valdes L,Saheba A,Urias E,Mendoza C,Fregoso OI,Llano M

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase.
Molecular and cellular biology27(15)5597-605(2007 Aug)
Fisher AE,Hochegger H,Takeda S,Caldecott KW

RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.
Molecular and cellular biology27(7)2562-71(2007 Apr)
Saberi A,Hochegger H,Szuts D,Lan L,Yasui A,Sale JE,Taniguchi Y,Murakawa Y,Zeng W,Yokomori K,Helleday T,Teraoka H,Arakawa H,Buerstedde JM,Takeda S

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.
Oncogene24(12)1982-93(2005 Mar)
Yu M,Schreek S,Cerni C,Schamberger C,Lesniewicz K,Poreba E,Vervoorts J,Walsemann G,Gr?tzinger J,Kremmer E,Mehraein Y,Mertsching J,Kraft R,Austen M,L?scher-Firzlaff J,L?scher B

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PARP1 cDNA ORF clone, Gallus gallus(chicken)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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