| Gene Symbol | FGA |
| Entrez Gene ID | 396307 |
| Full Name | fibrinogen alpha chain |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Gallus gallus(chicken) |
The following FGA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OGa00158 | |
| Clone ID Related Accession (Same CDS sequence) | NM_205356.2 | |
| Accession Version | NM_205356.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-23 | |
| Organism | Gallus gallus(chicken) | |
| Product | fibrinogen alpha chain isoform 2 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG641954.1, M34096.1, AADN05000019.1 and BU125048.1. On Dec 12, 2012 this sequence version replaced NM_205356.1. Transcript Variant: This variant (2) differs in the 3' UTR, and uses an alternate exon structure in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to variant 1. Sequence Note: This RefSeq record was created from transcripts of different breeds and genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BG641954.1, M34096.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201370, SAMEA2201378 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGATACCAG TGACGATACT CTGTGTGTTG CTCTGCCTCA ATTTAGCTTG GGCTCAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_990687.2 |
| CDS | 28..1557 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_205356.2 |
1 | ATGATACCAG TGACGATACT CTGTGTGTTG CTCTGCCTCA ATTTAGCTTG GGCTCAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OGa00028 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001271911.1 | |
| Accession Version | NM_001271911.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2226bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Gallus gallus(chicken) | |
| Product | fibrinogen alpha chain isoform 1 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG641954.1, AADN05000019.1, BU251255.1, BU124839.1 and BU125048.1. On Dec 13, 2012 this sequence version replaced XM_001232366.2. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcripts of different breeds and genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2201370 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## | |
1 | ATGATACCAG TGACGATACT CTGTGTGTTG CTCTGCCTCA ATTTAGCTTG GGCTCAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001258840.1 |
| CDS | 28..2253 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001271911.1 |
1 | ATGATACCAG TGACGATACT CTGTGTGTTG CTCTGCCTCA ATTTAGCTTG GGCTCAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Substitution of the human ?C region with the analogous chicken domain generates a fibrinogen with severely impaired lateral aggregation: fibrin monomers assemble into protofibrils but protofibrils do not assemble into fibers. |
Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index. |
A comprehensive collection of chicken cDNAs. |
Crystal structure of native chicken fibrinogen at 2.7 A resolution. |
Crystal structure of native chicken fibrinogen at 5.5-A resolution. |
