Gene Symbol | FTO |
Entrez Gene ID | 415718 |
Full Name | FTO, alpha-ketoglutarate dependent dioxygenase |
General protein information |
|
Gene Type | protein-coding |
Organism | Gallus gallus(chicken) |
ORF » Species Summary » Gallus gallus » FTO cDNA ORF clone
Gene Symbol | FTO |
Entrez Gene ID | 415718 |
Full Name | FTO, alpha-ketoglutarate dependent dioxygenase |
General protein information |
|
Gene Type | protein-coding |
Organism | Gallus gallus(chicken) |
mRNA | Protein | Name |
---|---|---|
NM_001185147.1 | NP_001172076.1 | alpha-ketoglutarate-dependent dioxygenase FTO |
Xenopus tropicalis (tropical clawed frog) | fto | NP_001017273.1 |
Homo sapiens (human) | FTO | NP_001073901.1 |
Pan troglodytes (chimpanzee) | FTO | XP_510968.2 |
Gallus gallus (chicken) | FTO | NP_001172076.1 |
Bos taurus (cattle) | FTO | NP_001091611.1 |
Rattus norvegicus (Norway rat) | Fto | NP_001034802.1 |
FTO | XP_001092038.1 | |
Danio rerio (zebrafish) | fto | XP_001345910.4 |
Canis lupus familiaris (dog) | FTO | XP_535301.4 |
Mus musculus (house mouse) | Fto | NP_036066.2 |
Tissue- and breed-specific expression of the chicken fat mass- and obesity-associated gene (FTO).
Song C, Song WT, Shu JT, Tao ZY, Zhu WQ, Di C, Li HF
Genetics and molecular research : GMR14(3)10500-6(2015 Sep)
Fatmass and obesity associated (FTO) gene regulates gluconeogenesis in chicken embryo fibroblast cells.
Guo F, Zhang Y, Zhang C, Wang S, Ni Y, Zhao R
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology179149-56(2015 Jan)
Expression of miR-33 from an SREBF2 intron targets the FTO gene in the chicken.
Shao F, Wang X, Yu J, Jiang H, Zhu B, Gu Z
PloS one9(3)e91236(2014)
Chicken FTO gene: tissue-specific expression, brain distribution, breed difference and effect of fasting.
Wang Y, Rao K, Yuan L, Everaert N, Buyse J, Grossmann R, Zhao R
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology163(3-4)246-52(2012 Nov)
Variation in sequence and expression of the avian FTO, and association with glucose metabolism, body weight, fatness and body composition in chickens.
Jia X, Nie Q, Lamont SJ, Zhang X
International journal of obesity (2005)36(8)1054-61(2012 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
FTO expression displays tissue- and breed-specific expression patterns.
Title: Tissue- and breed-specific expression of the chicken fat mass- and obesity-associated gene (FTO).
chicken FTO regulates gluconeogenesis in DF-1 cells through enhanced transcriptional regulation of G6PC gene by C/EBP-beta and phospho-CREB1.
Title: Fatmass and obesity associated (FTO) gene regulates gluconeogenesis in chicken embryo fibroblast cells.
miR-33 from an SREBF2 intron might play an important role in lipid metabolism in the chicken liver by negatively regulating the expression of the FTO gene
Title: Expression of miR-33 from an SREBF2 intron targets the FTO gene in the chicken.
Adult layers expressed higher FTO mRNA in liver and visceral fat, while adult broilers showed higher expression in hypothalamus and cerebellum.
Title: Chicken FTO gene: tissue-specific expression, brain distribution, breed difference and effect of fasting.
These data collectively indicate that FTO is related to glucose metabolism, body weight, fatness and body composition in birds, thus expanding knowledge of FTO function to non-mammalian species.
Title: Variation in sequence and expression of the avian FTO, and association with glucose metabolism, body weight, fatness and body composition in chickens.
The following FTO gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FTO cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OGa25736 | |
Clone ID Related Accession (Same CDS sequence) | NM_001185147.1 | |
Accession Version | NM_001185147.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-12-15 | |
Organism | Gallus gallus(chicken) | |
Product | alpha-ketoglutarate-dependent dioxygenase FTO | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from HM050377.1. On Jun 8, 2010 this sequence version replaced XM_414084.1. ##Evidence-Data-START## Transcript exon combination :: HM050377.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGAAGAGGA GAGCAGGGGA GCGGGAGAAG GAACTGAAGA AAAAAAAGCT TCTTGAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001172076.1 |
CDS | 81..1604 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001185147.1 |
1 | ATGAAGAGGA GAGCAGGGGA GCGGGAGAAG GAACTGAAGA AAAAAAAGCT TCTTGAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Tissue- and breed-specific expression of the chicken fat mass- and obesity-associated gene (FTO). |
Fatmass and obesity associated (FTO) gene regulates gluconeogenesis in chicken embryo fibroblast cells. |
Expression of miR-33 from an SREBF2 intron targets the FTO gene in the chicken. |
Chicken FTO gene: tissue-specific expression, brain distribution, breed difference and effect of fasting. |
Variation in sequence and expression of the avian FTO, and association with glucose metabolism, body weight, fatness and body composition in chickens. |