FGF4 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Gene Symbol	FGF4
Entrez Gene ID	428857
Full Name	fibroblast growth factor 4
General protein information	Preferred Names fibroblast growth factor 4 Names fibroblast growth factor 4 FGF-4 HBGF-4 fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) heparin-binding growth factor 4
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA Protein Name

NM_001031546.2 NP_001026717.2 fibroblast growth factor 4 precursor
Pathways from BioSystems

mRNA	Protein	Name
NM_001031546.2	NP_001026717.2	fibroblast growth factor 4 precursor

Homologies

	FGF4	XP_001100747.1
Xenopus tropicalis (tropical clawed frog)	fgf4	NP_001136294.1
Homo sapiens (human)	FGF4	NP_001998.1
Bos taurus (cattle)	FGF4	NP_001035695.2
Danio rerio (zebrafish)	fgf4	NP_571710.1
Pan troglodytes (chimpanzee)	FGF4	XP_001173970.1
Canis lupus familiaris (dog)	FGF4	XP_540801.2
Mus musculus (house mouse)	Fgf4	NP_034332.2
Rattus norvegicus (Norway rat)	Fgf4	NP_446261.1
Gallus gallus (chicken)	FGF4	NP_001026717.1

Gene Ontology
Bibliography

Related articles in PubMed

Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis.
Bayha E, J?rgensen MC, Serup P, Grapin-Botton A
PloS one4(6)e5845(2009 Jun)

BMP and FGF regulatory pathways in semilunar valve precursor cells.
Zhao B, Etter L, Hinton RB Jr, Benson DW
Developmental dynamics : an official publication of the American Association of Anatomists236(4)971-80(2007 Apr)

NOGO-A induction and localization during chick brain development indicate a role disparate from neurite outgrowth inhibition.
Caltharp SA, Pira CU, Mishima N, Youngdale EN, McNeill DS, Liwnicz BH, Oberg KC
BMC developmental biology732(2007 Apr)

Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation.
Kavanagh E, Church VL, Osborne AC, Lamb KJ, Archer CW, Francis-West PH, Pitsillides AA
Developmental dynamics : an official publication of the American Association of Anatomists235(3)826-34(2006 Mar)

FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo.
Dessimoz J, Opoka R, Kordich JJ, Grapin-Botton A, Wells JM
Mechanisms of development123(1)42-55(2006 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the RA pathway acts synergistically with FGF4 in endoderm patterning rather than mediating FGF4 activity
Title: Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis.

FGF4 treatment increased phosphorylated MAPK (dpERK) signaling and promoted expression of scleraxis and tenascin in embryonic valves.
Title: BMP and FGF regulatory pathways in semilunar valve precursor cells.

NOGO-A is up-regulated by FGF4 during brain development.
Title: NOGO-A induction and localization during chick brain development indicate a role disparate from neurite outgrowth inhibition.

Role of FGF4 in cavitation was shown.
Title: Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation.

FGF4-mediated signaling is required for establishing gut tube domains along the A-P axis
Title: FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo.

The following FGF4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGF4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa28652	NM_001031546.2 Latest version!	Gallus gallus fibroblast growth factor 4 (FGF4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FGF4 ( NM_001031546.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001026717.2 Gallus gallus fibroblast growth factor 4 (FGF4), mRNA.

Price & Availability↑

CloneID	OGa28652
Clone ID Related Accession (Same CDS sequence)	NM_001031546.2
Accession Version	NM_001031546.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-26
Organism	Gallus gallus(chicken)
Product	fibroblast growth factor 4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN03004474.1 and U14654.1. On Mar 18, 2015 this sequence version replaced NM_001031546.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SRS352360, SRS353381 [ECO:0000350] ##Evidence-Data-END##

ATGCCTCTCC CCGCGGCGCT GCTACCGGCG CTGCTCCTGG GGCTGCTGTG GCCGGGGGCG 
GTGCGCGGCC GGCCGCCCCC GGGCCGCCTC CCCGCCGGGC CCCGCCAGCG GCGCTGGGAC 
GCGGCTCTCT TCGCCCGCTC CGTGGCACGT CTCCCGGCCG AGCGCCGCGA CGCCGCCCGC 
GACGGCGACT ACCTCCTGGG CTACAAGCGG CTGCGGCGTC TCTATTGCAA CGTGGGCATC 
GGCTTCCACA TCCAGGTCCT GCCCGACGGC CGGATCGACG GGATCCACAG CGAGAACCGA 
TACAGTCTGC TGGAAATCTC CCCTGTGGAA AGAGGAGTGG TGAGCATATT TGGTGTTAGA 
AGTGGACTCT TCGTGGCCAT GAATAGCAAA GGCAAACTCT ATGGATCTAC CCATGTCAAT 
GATGAGTGCA AATTCAAAGA GATCCTCCTG CCAAACAACT ACAATGCTTA CGAATCCAGG 
ATTTATCCCG GGATGTACAT AGCCCTGAGC AAAAACGGAA GAACAAAGAA AGGCAATAAA 
GTATCTCCCA CAATGACGGT GACACATTTT CTTCCTAGAA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026717.2
CDS	1..585
Translation	MPLPAALLPALLLGLLWPGAVRGRPPPGRLPAGPRQRRWDAALFARSVARLPAERRDAARDGDYLLGYKRLRRLYCNVGIGFHIQVLPDGRIDGIHSENRYSLLEISPVERGVVSIFGVRSGLFVAMNSKGKLYGSTHVNDECKFKEILLPNNYNAYESRIYPGMYIALSKNGRTKKGNKVSPTMTVTHFLPRI

Target ORF information:

RefSeq Version	NM_001031546.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus fibroblast growth factor 4 (FGF4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001031546.2

ORF Insert Sequence:

ATGCCTCTCC CCGCGGCGCT GCTACCGGCG CTGCTCCTGG GGCTGCTGTG GCCGGGGGCG 
GTGCGCGGCC GGCCGCCCCC GGGCCGCCTC CCCGCCGGGC CCCGCCAGCG GCGCTGGGAC 
GCGGCTCTCT TCGCCCGCTC CGTGGCACGT CTCCCGGCCG AGCGCCGCGA CGCCGCCCGC 
GACGGCGACT ACCTCCTGGG CTACAAGCGG CTGCGGCGTC TCTATTGCAA CGTGGGCATC 
GGCTTCCACA TCCAGGTCCT GCCCGACGGC CGGATCGACG GGATCCACAG CGAGAACCGA 
TACAGTCTGC TGGAAATCTC CCCTGTGGAA AGAGGAGTGG TGAGCATATT TGGTGTTAGA 
AGTGGACTCT TCGTGGCCAT GAATAGCAAA GGCAAACTCT ATGGATCTAC CCATGTCAAT 
GATGAGTGCA AATTCAAAGA GATCCTCCTG CCAAACAACT ACAATGCTTA CGAATCCAGG 
ATTTATCCCG GGATGTACAT AGCCCTGAGC AAAAACGGAA GAACAAAGAA AGGCAATAAA 
GTATCTCCCA CAATGACGGT GACACATTTT CTTCCTAGAA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis.
PloS one4(6)e5845(2009 Jun)
Bayha E,J?rgensen MC,Serup P,Grapin-Botton A

BMP and FGF regulatory pathways in semilunar valve precursor cells.
Developmental dynamics : an official publication of the American Association of Anatomists236(4)971-80(2007 Apr)
Zhao B,Etter L,Hinton RB Jr,Benson DW

NOGO-A induction and localization during chick brain development indicate a role disparate from neurite outgrowth inhibition.
BMC developmental biology732(2007 Apr)
Caltharp SA,Pira CU,Mishima N,Youngdale EN,McNeill DS,Liwnicz BH,Oberg KC

Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation.
Developmental dynamics : an official publication of the American Association of Anatomists235(3)826-34(2006 Mar)
Kavanagh E,Church VL,Osborne AC,Lamb KJ,Archer CW,Francis-West PH,Pitsillides AA

FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo.
Mechanisms of development123(1)42-55(2006 Jan)
Dessimoz J,Opoka R,Kordich JJ,Grapin-Botton A,Wells JM

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FGF4 cDNA ORF clone, Gallus gallus(chicken)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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