Gene Symbol | CRYAA2 |
Entrez Gene ID | 102724652 |
Full Name | crystallin alpha A2 |
Synonyms | CRYAA |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » CRYAA2 cDNA ORF clone
Gene Symbol | CRYAA2 |
Entrez Gene ID | 102724652 |
Full Name | crystallin alpha A2 |
Synonyms | CRYAA |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001314050.2 | NP_001300979.1 | alpha-crystallin A2 chain isoform 1 |
NM_001320719.1 | NP_001307648.1 | alpha-crystallin A2 chain isoform 2 |
NM_001314050.4 | NP_001300979.1 | alpha-crystallin A2 chain isoform 1 |
Homo sapiens (human) | CRYAA | NP_000385.1 |
Pan troglodytes (chimpanzee) | CRYAA | XP_514927.2 |
Canis lupus familiaris (dog) | CRYAA | NP_001074367.1 |
Mus musculus (house mouse) | Cryaa | NP_038529.1 |
Gallus gallus (chicken) | CRYAA | NP_001025968.1 |
Homo sapiens (human) | LOC102724652 | XP_006723993.1 |
Danio rerio (zebrafish) | cryaa | NP_694482.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007159 | XP_308609.4 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005548 | XP_315550.4 |
Bos taurus (cattle) | CRYAA | NP_776714.1 |
Rattus norvegicus (Norway rat) | Cryaa | NP_036666.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007158 | XP_308610.4 |
Xenopus tropicalis (tropical clawed frog) | LOC100488185 | XP_002944595.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005547 | XP_315549.4 |
CRISPR/Cas9-Mediated Mutation of ?A-Crystallin Gene Induces Congenital Cataracts in Rabbits.
Yuan L, Yao H, Xu Y, Chen M, Deng J, Song Y, Sui T, Wang Y, Huang Y, Li Z, Lai L
Investigative ophthalmology & visual science58(6)BIO34-BIO41(2017 May)
Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts.
Wistow G, Bernstein SL, Wyatt MK, Ray S, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K
Molecular vision8196-204(2002 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
CRISPR/Cas9-mediated mutation of the alphaA-crystallin gene in rabbits recapitulates phenotypes of congenital cataracts, microphthalmia, obscurity, and early atrophy of the lens, and failed differentiation of lens fibers.
Title: CRISPR/Cas9-Mediated Mutation of ?A-Crystallin Gene Induces Congenital Cataracts in Rabbits.
The following CRYAA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CRYAA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu53183 | |
Clone ID Related Accession (Same CDS sequence) | NM_001314050.2 , NM_001314050.4 | |
Accession Version | NM_001314050.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-30 | |
Organism | Homo sapiens(human) | |
Product | alpha-crystallin A2 chain isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF726318.1, BC069528.1 and BM671946.1. On Mar 4, 2016 this sequence version replaced NM_001314050.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: ERR279859.771.1, ERR279871.3999.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, longest protein ##RefSeq-Attributes-END## |
1 | ATGGATGTGA CCATCCAGCA CCCCTGGTTC AAGCGCACCC TGGGGCCCTT CTACCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300979.1 |
CDS | 60..581 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001314050.2 |
1 | ATGGATGTGA CCATCCAGCA CCCCTGGTTC AAGCGCACCC TGGGGCCCTT CTACCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53184 | |
Clone ID Related Accession (Same CDS sequence) | NM_001320719.1 | |
Accession Version | NM_001320719.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Homo sapiens(human) | |
Product | alpha-crystallin A2 chain isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ640485.1 and BM671946.1. On or before Mar 4, 2016 this sequence version replaced XM_006723931.2, XM_006726802.2. ##Evidence-Data-START## Transcript exon combination :: ERR279833.1640.1, ERR279843.8427.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCTGTCT GTCCAGGAGA CAGTCACAGG CCCCCGAAAG CTCTGCCCCA CTTGGTGTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001307648.1 |
CDS | 97..507 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001320719.1 |
1 | ATGCCTGTCT GTCCAGGAGA CAGTCACAGG CCCCCGAAAG CTCTGCCCCA CTTGGTGTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53183 | |
Clone ID Related Accession (Same CDS sequence) | NM_001314050.2 , NM_001314050.4 | |
Accession Version | NM_001314050.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-02 | |
Organism | Homo sapiens(human) | |
Product | alpha-crystallin A2 chain isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FP236240.8. On Jan 3, 2020 this sequence version replaced NM_001314050.3. ##Evidence-Data-START## Transcript exon combination :: KM220589.1, ERR279875.6795.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, longest protein ##RefSeq-Attributes-END## |
1 | ATGGATGTGA CCATCCAGCA CCCCTGGTTC AAGCGCACCC TGGGGCCCTT CTACCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300979.1 |
CDS | 68..589 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001314050.4 |
1 | ATGGATGTGA CCATCCAGCA CCCCTGGTTC AAGCGCACCC TGGGGCCCTT CTACCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CRISPR/Cas9-Mediated Mutation of ?A-Crystallin Gene Induces Congenital Cataracts in Rabbits. |
Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts. |