Gene Symbol | TMEM147 |
Entrez Gene ID | 10430 |
Full Name | transmembrane protein 147 |
Synonyms | NIFIE14 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » TMEM147 cDNA ORF clone
Gene Symbol | TMEM147 |
Entrez Gene ID | 10430 |
Full Name | transmembrane protein 147 |
Synonyms | NIFIE14 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001242598.1 | NP_001229527.1 | transmembrane protein 147 isoform 3 |
NM_032635.4 | NP_116024.1 | transmembrane protein 147 isoform 1 |
NM_001242597.1 | NP_001229526.1 | transmembrane protein 147 isoform 2 |
NM_032635.3 | NP_116024.1 | transmembrane protein 147 isoform 1 |
NM_001242598.2 | NP_001229527.1 | transmembrane protein 147 isoform 3 |
NM_001242597.2 | NP_001229526.1 | transmembrane protein 147 isoform 2 |
Mus musculus (house mouse) | Tmem147 | NP_081491.2 |
Danio rerio (zebrafish) | tmem147 | NP_001002484.1 |
Caenorhabditis elegans (roundworm) | ZK418.5 | NP_498544.1 |
Homo sapiens (human) | TMEM147 | NP_116024.1 |
TMEM147 | XP_001095445.1 | |
Rattus norvegicus (Norway rat) | Tmem147 | NP_001033583.1 |
Oryza sativa (rice) | Os03g0766000 | NP_001051379.2 |
Canis lupus familiaris (dog) | TMEM147 | XP_533692.1 |
Bos taurus (cattle) | TMEM147 | NP_001029796.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008757 | XP_314877.2 |
Drosophila melanogaster (fruit fly) | CG5861 | NP_609789.1 |
Arabidopsis thaliana (thale cress) | AT1G47640 | NP_564509.1 |
Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)
Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex.
Dettmer U, Kuhn PH, Abou-Ajram C, Lichtenthaler SF, Kr?ger M, Kremmer E, Haass C, Haffner C
The Journal of biological chemistry285(34)26174-81(2010 Aug)
Transcriptome analysis of human gastric cancer.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)
Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.
Lehner B, Semple JI, Brown SE, Counsell D, Campbell RD, Sanderson CM
Genomics83(1)153-67(2004 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TMEM147 is a novel core component of the Nicalin-NOMO complex, further emphasizing its similarity with gamma-secretase.
Title: Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex.
The following TMEM147 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM147 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu55834 | |
Clone ID Related Accession (Same CDS sequence) | NM_001242597.1 , NM_001242597.2 | |
Accession Version | NM_001242597.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-24 | |
Organism | Homo sapiens(human) | |
Product | transmembrane protein 147 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM423809.1, BG697070.1, AW473288.1 and AW130399.1. Transcript Variant: This variant (2) lacks a splice site in the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.47134.1, SRR1163658.279395.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTGTTCT TGGCCACTTT CTTTCCCACC TGGGAAGGCG GCATCTATGA CTTCATTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001229526.1 |
CDS | 359..886 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001242597.1 |
1 | ATGCTGTTCT TGGCCACTTT CTTTCCCACC TGGGAAGGCG GCATCTATGA CTTCATTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu55834 | |
Clone ID Related Accession (Same CDS sequence) | NM_001242597.1 , NM_001242597.2 | |
Accession Version | NM_001242597.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-10 | |
Organism | Homo sapiens(human) | |
Product | transmembrane protein 147 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM423809.1, BG697070.1, AW473288.1 and AW130399.1. On May 31, 2019 this sequence version replaced NM_001242597.1. Transcript Variant: This variant (2) lacks a splice site in the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.226436.1, SRR1163657.26227.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTGTTCT TGGCCACTTT CTTTCCCACC TGGGAAGGCG GCATCTATGA CTTCATTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001229526.1 |
CDS | 333..860 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001242597.2 |
1 | ATGCTGTTCT TGGCCACTTT CTTTCCCACC TGGGAAGGCG GCATCTATGA CTTCATTGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu55915 | |
Clone ID Related Accession (Same CDS sequence) | NM_032635.4 , NM_032635.3 | |
Accession Version | NM_032635.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-09 | |
Organism | Homo sapiens(human) | |
Product | transmembrane protein 147 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM423809.1, BC001118.2 and AW130399.1. On Nov 23, 2018 this sequence version replaced NM_032635.3. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR5189658.62246.1, SRR1163655.97135.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000222284.10/ ENSP00000222284.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_116024.1 |
CDS | 115..789 |
Translation |
Target ORF information:
Target ORF information:
|
NM_032635.4 |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu55915 | |
Clone ID Related Accession (Same CDS sequence) | NM_032635.4 , NM_032635.3 | |
Accession Version | NM_032635.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | transmembrane protein 147 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM423809.1, BC001118.2 and AW130399.1. On Jun 16, 2011 this sequence version replaced NM_032635.2. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1163657.269744.1, SRR1163655.444231.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_116024.1 |
CDS | 141..815 |
Translation |
Target ORF information:
Target ORF information:
|
NM_032635.3 |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06928 | |
Clone ID Related Accession (Same CDS sequence) | NM_001242598.1 , NM_001242598.2 | |
Accession Version | NM_001242598.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-24 | |
Organism | Homo sapiens(human) | |
Product | transmembrane protein 147 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM423809.1, BM765457.1 and AW130399.1. Transcript Variant: This variant (3) lacks two consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BM765457.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001229527.1 |
CDS | 141..593 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001242598.1 |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06928 | |
Clone ID Related Accession (Same CDS sequence) | NM_001242598.1 , NM_001242598.2 | |
Accession Version | NM_001242598.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-10 | |
Organism | Homo sapiens(human) | |
Product | transmembrane protein 147 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM423809.1, BM765457.1 and AW130399.1. On May 31, 2019 this sequence version replaced NM_001242598.1. Transcript Variant: This variant (3) lacks two consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BM765457.1, DRR138512.395010.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001229527.1 |
CDS | 115..567 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001242598.2 |
1 | ATGACCCTGT TTCACTTCGG GAACTGCTTC GCTCTTGCCT ACTTCCCCTA CTTCATCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Architecture of the human interactome defines protein communities and disease networks. |
Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex. |
Transcriptome analysis of human gastric cancer. |
Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |