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WDR3 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol WDR3
Entrez Gene ID 10885
Full Name WD repeat domain 3
Synonyms DIP2,UTP12
General protein information
Preferred Names

WD repeat domain 3

Names

WD repeat-containing protein 3
dJ776P7.2 (WD repeat domain 3)
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

1

1p12
Summary This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008].
Disorder MIM:

604737


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_006784.3 NP_006775.1 WD repeat-containing protein 3
NM_006784.2 NP_006775.1 WD repeat-containing protein 3

Pathways from BioSystems


Homologies


Gallus gallus (chicken) WDR3 NP_001026656.1
Drosophila melanogaster (fruit fly) CG8064 NP_650705.1
Caenorhabditis elegans (roundworm) F13H8.2 NP_495256.1
Eremothecium gossypii AGOS_AGL196C NP_986471.2
Saccharomyces cerevisiae (baker's yeast) DIP2 NP_013230.1
Neurospora crassa NCU03051 XP_963715.1
Pan troglodytes (chimpanzee) WDR3 XP_524820.3
Magnaporthe oryzae (rice blast fungus) MGG_04746 XP_003713707.1
Xenopus tropicalis (tropical clawed frog) wdr3 NP_989242.1
Homo sapiens (human) WDR3 NP_006775.1
WDR3 XP_001113399.1
Bos taurus (cattle) WDR3 NP_001179317.1
Mus musculus (house mouse) Wdr3 NP_780761.1
Rattus norvegicus (Norway rat) Wdr3 NP_001101175.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP001146 XP_322015.3
Schizosaccharomyces pombe (fission yeast) SPBC3D6.12 NP_595524.1
Canis lupus familiaris (dog) WDR3 XP_540261.2
Danio rerio (zebrafish) wdr3 NP_942574.1
Kluyveromyces lactis KLLA0D16390g XP_453783.1
Arabidopsis thaliana (thale cress) AT3G21540 NP_188791.3
Oryza sativa (rice) Os03g0151700 NP_001048986.1

Gene Ontology


Bibliography

Related articles in PubMed

Association studies of WD repeat domain 3 and chitobiosyldiphosphodolichol beta-mannosyltransferase genes with schizophrenia in a Japanese population.
Kobayashi M, Jitoku D, Iwayama Y, Yamamoto N, Toyota T, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Kurumaji A, Yoshikawa T, Nishikawa T
PloS one13(1)e0190991(2018)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Possible role of the WDR3 gene on genome stability in thyroid cancer patients.
Garc?a-Quispes WA, Pastor S, Galofr? P, Biarn?s J, Castell J, Vel?zquez A, Marcos R
PloS one7(9)e44288(2012)

WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.
Akdi A, Gim?nez EM, Garc?a-Quispes W, Pastor S, Castell J, Biarn?s J, Marcos R, Vel?zquez A
Thyroid : official journal of the American Thyroid Association20(7)803-9(2010 Jul)

Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation.
McMahon M, Ayll?n V, Panov KI, O'Connor R
The Journal of biological chemistry285(24)18309-18(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

WDR3 can modulate genome stability in thyroid cancer patients.
Title: Possible role of the WDR3 gene on genome stability in thyroid cancer patients.

Observational study of gene-disease association. (HuGE Navigator)
Title: WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.

WDR3 has an essential function in 40 S ribosomal subunit synthesis and in ribosomal stress signaling to p53-mediated regulation of cell cycle progression in cancer cells
Title: Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation.

The following WDR3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WDR3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu05794 NM_006784.3
Latest version!		 Homo sapiens WD repeat domain 3 (WDR3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $657.30
$939.00
View Old Accession Versions >>
OHu05794 NM_006784.2 Homo sapiens WD repeat domain 3 (WDR3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $657.30
$939.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu05794
Clone ID Related Accession (Same CDS sequence) NM_006784.3 , NM_006784.2
Accession Version NM_006784.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2832bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-26
Organism Homo sapiens(human)
Product WD repeat-containing protein 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121993.7, BP281064.1, AK292438.1, AF083217.1, BU685597.1 and AA258068.1. On Nov 22, 2018 this sequence version replaced NM_006784.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.27264.1, SRR1660807.233060.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000349139.6/ ENSP00000308179.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGGGGCTCA CCAAGCAGTA CCTACGCTAT GTTGCTAGTG CGGTCTTTGG CGTTATCGGC 
AGCCAAAAAG GTAATATTGT CTTTGTGACA CTTCGTGGTG AGAAAGGACG TTATGTGGCA 
GTACCAGCTT GTGAACACGT TTTCATCTGG GACTTAAGGA AAGGAGAGAA GATTCTTATC 
CTTCAGGGGC TTAAACAAGA AGTTACTTGC TTATGCCCCT CCCCAGATGG GCTACACTTA 
GCTGTTGGGT ATGAGGATGG GTCGATCCGA ATCTTCAGTC TCCTGAGTGG GGAAGGAAAT 
GTGACCTTCA ATGGTCACAA AGCAGCTATC ACTACCTTGA AGTATGATCA GCTAGGAGGC 
AGACTGGCAT CTGGGTCCAA GGACACAGAT ATTATTGTAT GGGATGTGAT CAATGAAAGT 
GGTCTGTACC GTCTAAAGGG GCACAAGGAT GCCATCACAC AAGCATTGTT TCTACGAGAA 
AAGAACCTGC TAGTTACTAG TGGGAAAGAT ACCATGGTGA AATGGTGGGA CCTTGATACT 
CAGCACTGCT TTAAAACAAT GGTTGGCCAC CGGACTGAGG TATGGGGGTT GGTTCTGTTG 
TCAGAAGAAA AGCGACTCAT CACTGGGGCC TCAGACAGTG AACTGAGGGT ATGGGACATA 
GCTTATCTGC AAGAGATTGA AGACCCGGAA GAACCAGACC CCAAGAAAAT CAAAGGATCT 
TCTCCTGGAA TACAAGATAC TCTTGAGGCA GAGGATGGTG CCTTTGAGAC GGATGAAGCC 
CCTGAGGATC GAATCCTTTC ATGCAGAAAA GCTGGTTCCA TAATGCGGGA AGGAAGAGAC 
AGAGTTGTAA ACCTTGCAGT CGACAAGACA GGCAGGATTC TTGCTTGCCA TGGAACTGAC 
TCTGTGCTAG AATTGTTTTG TATCCTTTCC AAAAAGGAAA TTCAGAAGAA AATGGATAAG 
AAGATGAAGA AAGCTAGAAA GAAAGCAAAA TTACATTCTA GCAAAGGAGA GGAGGAAGAT 
CCTGAGGTTA ATGTTGAAAT GAGTCTGCAA GATGAAATCC AGCGGGTGAC TAATATAAAA 
ACTTCTGCCA AAATCAAGTC CTTTGACTTG ATTCATTCAC CTCACGGAGA GTTAAAGGCT 
GTCTTCCTGC TGCAGAACAA CCTGGTGGAA TTGTATTCAC TGAATCCATC CTTGCCTACT 
CCTCAGCCTG TCAGGACAAG CAGAATCACT ATTGGGGGTC ATCGCAGTGA TGTGCGGACT 
TTGTCATTCA GCTCAGACAA TATTGCTGTT CTTTCAGCTG CAGCTGATTC CATTAAAATA 
TGGAACAGGT CTACACTGCA GTGTATTCGC ACAATGACCT GTGAATATGC ACTTTGCTCA 
TTCTTTGTAC CTGGTGATAG ACAGGTAGTC ATAGGAACAA AGACAGGGAA GCTGCAGCTT 
TATGACTTGG CTTCAGGGAA TCTGCTGGAG ACAATAGATG CACATGATGG AGCTTTGTGG 
TCCATGTCCC TCTCTCCAGA TCAGCGTGGC TTTGTGACAG GTGGTGCAGA TAAATCTGTC 
AAATTCTGGG ATTTTGAGTT AGTGAAAGAT GAAAATAGTA CCCAAAAGAG ACTTTCTGTG 
AAGCAAACCC GAACTTTGCA ACTAGATGAA GATGTTCTGT GTGTCAGTTA CTCTCCCAAT 
CAAAAGCTAT TGGCTGTGTC TTTGCTGGAC TGTACTGTGA AAATTTTCTA CGTTGATACT 
TTAAAGTTTT TTCTGTCACT GTATGGACAC AAACTGCCTG TTATATGCAT GGACATCTCT 
CATGATGGAG CACTCATAGC AACTGGCTCC GCTGATAGGA ATGTGAAAAT CTGGGGTTTG 
GACTTTGGGG ACTGCCACAA GTCTCTCTTT GCACATGATG ACAGTGTGAT GTACCTACAG 
TTTGTACCCA AGTCTCACCT CTTCTTCACT GCCGGAAAAG ATCATAAGAT TAAACAGTGG 
GATGCAGACA AATTTGAACA CATACAGACT CTGGAGGGTC ATCACCAGGA AATATGGTGT 
TTGGCTGTAA GCCCCAGTGG AGACTATGTT GTATCATCGT CCCATGACAA ATCTCTGAGA 
CTTTGGGAGA GAACAAGGGA GCCTCTTATT CTTGAGGAAG AAAGGGAGAT GGAAAGAGAA 
GCAGAATATG AGGAGAGTGT GGCCAAAGAA GACCAACCAG CAGTTCCAGG AGAGACTCAA 
GGTGACAGTT ACTTTACTGG AAAGAAAACT ATTGAAACAG TGAAAGCAGC TGAGAGGATT 
ATGGAGGCTA TTGAGTTGTA CCGAGAAGAA ACTGCAAAAA TGAAGGAACA CAAAGCCATT 
TGTAAAGCTG CAGGGAAAGA GGTTCCACTT CCCAGCAACC CCATCCTAAT GGCTTATGGC 
AGTATCTCAC CTTCAGCTTA TGTATTAGAG ATTTTTAAAG GGATCAAGTC GAGTGAGCTG 
GAAGAATCTC TACTTGTGCT GCCTTTCTCT TATGTCCCAG ACATTCTTAA ACTCTTTAAC 
GAATTCATTC AGCTGGGCTC TGATGTTGAA CTTATATGCC GGTGCCTCTT CTTCCTCCTT 
AGGATTCACT TTGGACAGAT CACTAGCAAT CAAATGCTTG TGCCAGTGAT AGAAAAATTA 
AGGGAAACAA CTATTTCAAA AGTCAGCCAA GTCCGGGATG TTATCGGCTT CAATATGGCT 
GGTCTTGATT ATCTCAAGAG GGAATGCGAG GCAAAAAGTG AAGTTATGTT TTTTGCTGAT 
GCTACTAGCC ACTTGGAAGA GAAGAAGAGG AAGAGGAAAA AGAGGGAGAA GTTGATTCTA 
ACGTTGACTT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_006775.1
CDS77..2908
Translation

Target ORF information:

RefSeq Version NM_006784.3
Organism Homo sapiens(human)
Definition Homo sapiens WD repeat domain 3 (WDR3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_006784.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGGGGCTCA CCAAGCAGTA CCTACGCTAT GTTGCTAGTG CGGTCTTTGG CGTTATCGGC 
AGCCAAAAAG GTAATATTGT CTTTGTGACA CTTCGTGGTG AGAAAGGACG TTATGTGGCA 
GTACCAGCTT GTGAACACGT TTTCATCTGG GACTTAAGGA AAGGAGAGAA GATTCTTATC 
CTTCAGGGGC TTAAACAAGA AGTTACTTGC TTATGCCCCT CCCCAGATGG GCTACACTTA 
GCTGTTGGGT ATGAGGATGG GTCGATCCGA ATCTTCAGTC TCCTGAGTGG GGAAGGAAAT 
GTGACCTTCA ATGGTCACAA AGCAGCTATC ACTACCTTGA AGTATGATCA GCTAGGAGGC 
AGACTGGCAT CTGGGTCCAA GGACACAGAT ATTATTGTAT GGGATGTGAT CAATGAAAGT 
GGTCTGTACC GTCTAAAGGG GCACAAGGAT GCCATCACAC AAGCATTGTT TCTACGAGAA 
AAGAACCTGC TAGTTACTAG TGGGAAAGAT ACCATGGTGA AATGGTGGGA CCTTGATACT 
CAGCACTGCT TTAAAACAAT GGTTGGCCAC CGGACTGAGG TATGGGGGTT GGTTCTGTTG 
TCAGAAGAAA AGCGACTCAT CACTGGGGCC TCAGACAGTG AACTGAGGGT ATGGGACATA 
GCTTATCTGC AAGAGATTGA AGACCCGGAA GAACCAGACC CCAAGAAAAT CAAAGGATCT 
TCTCCTGGAA TACAAGATAC TCTTGAGGCA GAGGATGGTG CCTTTGAGAC GGATGAAGCC 
CCTGAGGATC GAATCCTTTC ATGCAGAAAA GCTGGTTCCA TAATGCGGGA AGGAAGAGAC 
AGAGTTGTAA ACCTTGCAGT CGACAAGACA GGCAGGATTC TTGCTTGCCA TGGAACTGAC 
TCTGTGCTAG AATTGTTTTG TATCCTTTCC AAAAAGGAAA TTCAGAAGAA AATGGATAAG 
AAGATGAAGA AAGCTAGAAA GAAAGCAAAA TTACATTCTA GCAAAGGAGA GGAGGAAGAT 
CCTGAGGTTA ATGTTGAAAT GAGTCTGCAA GATGAAATCC AGCGGGTGAC TAATATAAAA 
ACTTCTGCCA AAATCAAGTC CTTTGACTTG ATTCATTCAC CTCACGGAGA GTTAAAGGCT 
GTCTTCCTGC TGCAGAACAA CCTGGTGGAA TTGTATTCAC TGAATCCATC CTTGCCTACT 
CCTCAGCCTG TCAGGACAAG CAGAATCACT ATTGGGGGTC ATCGCAGTGA TGTGCGGACT 
TTGTCATTCA GCTCAGACAA TATTGCTGTT CTTTCAGCTG CAGCTGATTC CATTAAAATA 
TGGAACAGGT CTACACTGCA GTGTATTCGC ACAATGACCT GTGAATATGC ACTTTGCTCA 
TTCTTTGTAC CTGGTGATAG ACAGGTAGTC ATAGGAACAA AGACAGGGAA GCTGCAGCTT 
TATGACTTGG CTTCAGGGAA TCTGCTGGAG ACAATAGATG CACATGATGG AGCTTTGTGG 
TCCATGTCCC TCTCTCCAGA TCAGCGTGGC TTTGTGACAG GTGGTGCAGA TAAATCTGTC 
AAATTCTGGG ATTTTGAGTT AGTGAAAGAT GAAAATAGTA CCCAAAAGAG ACTTTCTGTG 
AAGCAAACCC GAACTTTGCA ACTAGATGAA GATGTTCTGT GTGTCAGTTA CTCTCCCAAT 
CAAAAGCTAT TGGCTGTGTC TTTGCTGGAC TGTACTGTGA AAATTTTCTA CGTTGATACT 
TTAAAGTTTT TTCTGTCACT GTATGGACAC AAACTGCCTG TTATATGCAT GGACATCTCT 
CATGATGGAG CACTCATAGC AACTGGCTCC GCTGATAGGA ATGTGAAAAT CTGGGGTTTG 
GACTTTGGGG ACTGCCACAA GTCTCTCTTT GCACATGATG ACAGTGTGAT GTACCTACAG 
TTTGTACCCA AGTCTCACCT CTTCTTCACT GCCGGAAAAG ATCATAAGAT TAAACAGTGG 
GATGCAGACA AATTTGAACA CATACAGACT CTGGAGGGTC ATCACCAGGA AATATGGTGT 
TTGGCTGTAA GCCCCAGTGG AGACTATGTT GTATCATCGT CCCATGACAA ATCTCTGAGA 
CTTTGGGAGA GAACAAGGGA GCCTCTTATT CTTGAGGAAG AAAGGGAGAT GGAAAGAGAA 
GCAGAATATG AGGAGAGTGT GGCCAAAGAA GACCAACCAG CAGTTCCAGG AGAGACTCAA 
GGTGACAGTT ACTTTACTGG AAAGAAAACT ATTGAAACAG TGAAAGCAGC TGAGAGGATT 
ATGGAGGCTA TTGAGTTGTA CCGAGAAGAA ACTGCAAAAA TGAAGGAACA CAAAGCCATT 
TGTAAAGCTG CAGGGAAAGA GGTTCCACTT CCCAGCAACC CCATCCTAAT GGCTTATGGC 
AGTATCTCAC CTTCAGCTTA TGTATTAGAG ATTTTTAAAG GGATCAAGTC GAGTGAGCTG 
GAAGAATCTC TACTTGTGCT GCCTTTCTCT TATGTCCCAG ACATTCTTAA ACTCTTTAAC 
GAATTCATTC AGCTGGGCTC TGATGTTGAA CTTATATGCC GGTGCCTCTT CTTCCTCCTT 
AGGATTCACT TTGGACAGAT CACTAGCAAT CAAATGCTTG TGCCAGTGAT AGAAAAATTA 
AGGGAAACAA CTATTTCAAA AGTCAGCCAA GTCCGGGATG TTATCGGCTT CAATATGGCT 
GGTCTTGATT ATCTCAAGAG GGAATGCGAG GCAAAAAGTG AAGTTATGTT TTTTGCTGAT 
GCTACTAGCC ACTTGGAAGA GAAGAAGAGG AAGAGGAAAA AGAGGGAGAA GTTGATTCTA 
ACGTTGACTT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu05794
Clone ID Related Accession (Same CDS sequence) NM_006784.3 , NM_006784.2
Accession Version NM_006784.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2832bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product WD repeat-containing protein 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP281064.1, AK292438.1, AF083217.1, BU685597.1 and AA258068.1. On Aug 27, 2008 this sequence version replaced NM_006784.1. ##Evidence-Data-START## Transcript exon combination :: AF083217.1, SRR1803614.144149.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGGGGCTCA CCAAGCAGTA CCTACGCTAT GTTGCTAGTG CGGTCTTTGG CGTTATCGGC 
AGCCAAAAAG GTAATATTGT CTTTGTGACA CTTCGTGGTG AGAAAGGACG TTATGTGGCA 
GTACCAGCTT GTGAACACGT TTTCATCTGG GACTTAAGGA AAGGAGAGAA GATTCTTATC 
CTTCAGGGGC TTAAACAAGA AGTTACTTGC TTATGCCCCT CCCCAGATGG GCTACACTTA 
GCTGTTGGGT ATGAGGATGG GTCGATCCGA ATCTTCAGTC TCCTGAGTGG GGAAGGAAAT 
GTGACCTTCA ATGGTCACAA AGCAGCTATC ACTACCTTGA AGTATGATCA GCTAGGAGGC 
AGACTGGCAT CTGGGTCCAA GGACACAGAT ATTATTGTAT GGGATGTGAT CAATGAAAGT 
GGTCTGTACC GTCTAAAGGG GCACAAGGAT GCCATCACAC AAGCATTGTT TCTACGAGAA 
AAGAACCTGC TAGTTACTAG TGGGAAAGAT ACCATGGTGA AATGGTGGGA CCTTGATACT 
CAGCACTGCT TTAAAACAAT GGTTGGCCAC CGGACTGAGG TATGGGGGTT GGTTCTGTTG 
TCAGAAGAAA AGCGACTCAT CACTGGGGCC TCAGACAGTG AACTGAGGGT ATGGGACATA 
GCTTATCTGC AAGAGATTGA AGACCCGGAA GAACCAGACC CCAAGAAAAT CAAAGGATCT 
TCTCCTGGAA TACAAGATAC TCTTGAGGCA GAGGATGGTG CCTTTGAGAC GGATGAAGCC 
CCTGAGGATC GAATCCTTTC ATGCAGAAAA GCTGGTTCCA TAATGCGGGA AGGAAGAGAC 
AGAGTTGTAA ACCTTGCAGT CGACAAGACA GGCAGGATTC TTGCTTGCCA TGGAACTGAC 
TCTGTGCTAG AATTGTTTTG TATCCTTTCC AAAAAGGAAA TTCAGAAGAA AATGGATAAG 
AAGATGAAGA AAGCTAGAAA GAAAGCAAAA TTACATTCTA GCAAAGGAGA GGAGGAAGAT 
CCTGAGGTTA ATGTTGAAAT GAGTCTGCAA GATGAAATCC AGCGGGTGAC TAATATAAAA 
ACTTCTGCCA AAATCAAGTC CTTTGACTTG ATTCATTCAC CTCACGGAGA GTTAAAGGCT 
GTCTTCCTGC TGCAGAACAA CCTGGTGGAA TTGTATTCAC TGAATCCATC CTTGCCTACT 
CCTCAGCCTG TCAGGACAAG CAGAATCACT ATTGGGGGTC ATCGCAGTGA TGTGCGGACT 
TTGTCATTCA GCTCAGACAA TATTGCTGTT CTTTCAGCTG CAGCTGATTC CATTAAAATA 
TGGAACAGGT CTACACTGCA GTGTATTCGC ACAATGACCT GTGAATATGC ACTTTGCTCA 
TTCTTTGTAC CTGGTGATAG ACAGGTAGTC ATAGGAACAA AGACAGGGAA GCTGCAGCTT 
TATGACTTGG CTTCAGGGAA TCTGCTGGAG ACAATAGATG CACATGATGG AGCTTTGTGG 
TCCATGTCCC TCTCTCCAGA TCAGCGTGGC TTTGTGACAG GTGGTGCAGA TAAATCTGTC 
AAATTCTGGG ATTTTGAGTT AGTGAAAGAT GAAAATAGTA CCCAAAAGAG ACTTTCTGTG 
AAGCAAACCC GAACTTTGCA ACTAGATGAA GATGTTCTGT GTGTCAGTTA CTCTCCCAAT 
CAAAAGCTAT TGGCTGTGTC TTTGCTGGAC TGTACTGTGA AAATTTTCTA CGTTGATACT 
TTAAAGTTTT TTCTGTCACT GTATGGACAC AAACTGCCTG TTATATGCAT GGACATCTCT 
CATGATGGAG CACTCATAGC AACTGGCTCC GCTGATAGGA ATGTGAAAAT CTGGGGTTTG 
GACTTTGGGG ACTGCCACAA GTCTCTCTTT GCACATGATG ACAGTGTGAT GTACCTACAG 
TTTGTACCCA AGTCTCACCT CTTCTTCACT GCCGGAAAAG ATCATAAGAT TAAACAGTGG 
GATGCAGACA AATTTGAACA CATACAGACT CTGGAGGGTC ATCACCAGGA AATATGGTGT 
TTGGCTGTAA GCCCCAGTGG AGACTATGTT GTATCATCGT CCCATGACAA ATCTCTGAGA 
CTTTGGGAGA GAACAAGGGA GCCTCTTATT CTTGAGGAAG AAAGGGAGAT GGAAAGAGAA 
GCAGAATATG AGGAGAGTGT GGCCAAAGAA GACCAACCAG CAGTTCCAGG AGAGACTCAA 
GGTGACAGTT ACTTTACTGG AAAGAAAACT ATTGAAACAG TGAAAGCAGC TGAGAGGATT 
ATGGAGGCTA TTGAGTTGTA CCGAGAAGAA ACTGCAAAAA TGAAGGAACA CAAAGCCATT 
TGTAAAGCTG CAGGGAAAGA GGTTCCACTT CCCAGCAACC CCATCCTAAT GGCTTATGGC 
AGTATCTCAC CTTCAGCTTA TGTATTAGAG ATTTTTAAAG GGATCAAGTC GAGTGAGCTG 
GAAGAATCTC TACTTGTGCT GCCTTTCTCT TATGTCCCAG ACATTCTTAA ACTCTTTAAC 
GAATTCATTC AGCTGGGCTC TGATGTTGAA CTTATATGCC GGTGCCTCTT CTTCCTCCTT 
AGGATTCACT TTGGACAGAT CACTAGCAAT CAAATGCTTG TGCCAGTGAT AGAAAAATTA 
AGGGAAACAA CTATTTCAAA AGTCAGCCAA GTCCGGGATG TTATCGGCTT CAATATGGCT 
GGTCTTGATT ATCTCAAGAG GGAATGCGAG GCAAAAAGTG AAGTTATGTT TTTTGCTGAT 
GCTACTAGCC ACTTGGAAGA GAAGAAGAGG AAGAGGAAAA AGAGGGAGAA GTTGATTCTA 
ACGTTGACTT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_006775.1
CDS67..2898
Translation

Target ORF information:

RefSeq Version NM_006784.2
Organism Homo sapiens(human)
Definition Homo sapiens WD repeat domain 3 (WDR3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_006784.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGGGGCTCA CCAAGCAGTA CCTACGCTAT GTTGCTAGTG CGGTCTTTGG CGTTATCGGC 
AGCCAAAAAG GTAATATTGT CTTTGTGACA CTTCGTGGTG AGAAAGGACG TTATGTGGCA 
GTACCAGCTT GTGAACACGT TTTCATCTGG GACTTAAGGA AAGGAGAGAA GATTCTTATC 
CTTCAGGGGC TTAAACAAGA AGTTACTTGC TTATGCCCCT CCCCAGATGG GCTACACTTA 
GCTGTTGGGT ATGAGGATGG GTCGATCCGA ATCTTCAGTC TCCTGAGTGG GGAAGGAAAT 
GTGACCTTCA ATGGTCACAA AGCAGCTATC ACTACCTTGA AGTATGATCA GCTAGGAGGC 
AGACTGGCAT CTGGGTCCAA GGACACAGAT ATTATTGTAT GGGATGTGAT CAATGAAAGT 
GGTCTGTACC GTCTAAAGGG GCACAAGGAT GCCATCACAC AAGCATTGTT TCTACGAGAA 
AAGAACCTGC TAGTTACTAG TGGGAAAGAT ACCATGGTGA AATGGTGGGA CCTTGATACT 
CAGCACTGCT TTAAAACAAT GGTTGGCCAC CGGACTGAGG TATGGGGGTT GGTTCTGTTG 
TCAGAAGAAA AGCGACTCAT CACTGGGGCC TCAGACAGTG AACTGAGGGT ATGGGACATA 
GCTTATCTGC AAGAGATTGA AGACCCGGAA GAACCAGACC CCAAGAAAAT CAAAGGATCT 
TCTCCTGGAA TACAAGATAC TCTTGAGGCA GAGGATGGTG CCTTTGAGAC GGATGAAGCC 
CCTGAGGATC GAATCCTTTC ATGCAGAAAA GCTGGTTCCA TAATGCGGGA AGGAAGAGAC 
AGAGTTGTAA ACCTTGCAGT CGACAAGACA GGCAGGATTC TTGCTTGCCA TGGAACTGAC 
TCTGTGCTAG AATTGTTTTG TATCCTTTCC AAAAAGGAAA TTCAGAAGAA AATGGATAAG 
AAGATGAAGA AAGCTAGAAA GAAAGCAAAA TTACATTCTA GCAAAGGAGA GGAGGAAGAT 
CCTGAGGTTA ATGTTGAAAT GAGTCTGCAA GATGAAATCC AGCGGGTGAC TAATATAAAA 
ACTTCTGCCA AAATCAAGTC CTTTGACTTG ATTCATTCAC CTCACGGAGA GTTAAAGGCT 
GTCTTCCTGC TGCAGAACAA CCTGGTGGAA TTGTATTCAC TGAATCCATC CTTGCCTACT 
CCTCAGCCTG TCAGGACAAG CAGAATCACT ATTGGGGGTC ATCGCAGTGA TGTGCGGACT 
TTGTCATTCA GCTCAGACAA TATTGCTGTT CTTTCAGCTG CAGCTGATTC CATTAAAATA 
TGGAACAGGT CTACACTGCA GTGTATTCGC ACAATGACCT GTGAATATGC ACTTTGCTCA 
TTCTTTGTAC CTGGTGATAG ACAGGTAGTC ATAGGAACAA AGACAGGGAA GCTGCAGCTT 
TATGACTTGG CTTCAGGGAA TCTGCTGGAG ACAATAGATG CACATGATGG AGCTTTGTGG 
TCCATGTCCC TCTCTCCAGA TCAGCGTGGC TTTGTGACAG GTGGTGCAGA TAAATCTGTC 
AAATTCTGGG ATTTTGAGTT AGTGAAAGAT GAAAATAGTA CCCAAAAGAG ACTTTCTGTG 
AAGCAAACCC GAACTTTGCA ACTAGATGAA GATGTTCTGT GTGTCAGTTA CTCTCCCAAT 
CAAAAGCTAT TGGCTGTGTC TTTGCTGGAC TGTACTGTGA AAATTTTCTA CGTTGATACT 
TTAAAGTTTT TTCTGTCACT GTATGGACAC AAACTGCCTG TTATATGCAT GGACATCTCT 
CATGATGGAG CACTCATAGC AACTGGCTCC GCTGATAGGA ATGTGAAAAT CTGGGGTTTG 
GACTTTGGGG ACTGCCACAA GTCTCTCTTT GCACATGATG ACAGTGTGAT GTACCTACAG 
TTTGTACCCA AGTCTCACCT CTTCTTCACT GCCGGAAAAG ATCATAAGAT TAAACAGTGG 
GATGCAGACA AATTTGAACA CATACAGACT CTGGAGGGTC ATCACCAGGA AATATGGTGT 
TTGGCTGTAA GCCCCAGTGG AGACTATGTT GTATCATCGT CCCATGACAA ATCTCTGAGA 
CTTTGGGAGA GAACAAGGGA GCCTCTTATT CTTGAGGAAG AAAGGGAGAT GGAAAGAGAA 
GCAGAATATG AGGAGAGTGT GGCCAAAGAA GACCAACCAG CAGTTCCAGG AGAGACTCAA 
GGTGACAGTT ACTTTACTGG AAAGAAAACT ATTGAAACAG TGAAAGCAGC TGAGAGGATT 
ATGGAGGCTA TTGAGTTGTA CCGAGAAGAA ACTGCAAAAA TGAAGGAACA CAAAGCCATT 
TGTAAAGCTG CAGGGAAAGA GGTTCCACTT CCCAGCAACC CCATCCTAAT GGCTTATGGC 
AGTATCTCAC CTTCAGCTTA TGTATTAGAG ATTTTTAAAG GGATCAAGTC GAGTGAGCTG 
GAAGAATCTC TACTTGTGCT GCCTTTCTCT TATGTCCCAG ACATTCTTAA ACTCTTTAAC 
GAATTCATTC AGCTGGGCTC TGATGTTGAA CTTATATGCC GGTGCCTCTT CTTCCTCCTT 
AGGATTCACT TTGGACAGAT CACTAGCAAT CAAATGCTTG TGCCAGTGAT AGAAAAATTA 
AGGGAAACAA CTATTTCAAA AGTCAGCCAA GTCCGGGATG TTATCGGCTT CAATATGGCT 
GGTCTTGATT ATCTCAAGAG GGAATGCGAG GCAAAAAGTG AAGTTATGTT TTTTGCTGAT 
GCTACTAGCC ACTTGGAAGA GAAGAAGAGG AAGAGGAAAA AGAGGGAGAA GTTGATTCTA 
ACGTTGACTT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Association studies of WD repeat domain 3 and chitobiosyldiphosphodolichol beta-mannosyltransferase genes with schizophrenia in a Japanese population.
PloS one13(1)e0190991(2018)
Kobayashi M,Jitoku D,Iwayama Y,Yamamoto N,Toyota T,Suzuki K,Kikuchi M,Hashimoto T,Kanahara N,Kurumaji A,Yoshikawa T,Nishikawa T


book

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW


book

Possible role of the WDR3 gene on genome stability in thyroid cancer patients.
PloS one7(9)e44288(2012)
Garc?a-Quispes WA,Pastor S,Galofr? P,Biarn?s J,Castell J,Vel?zquez A,Marcos R


book

WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.
Thyroid : official journal of the American Thyroid Association20(7)803-9(2010 Jul)
Akdi A,Gim?nez EM,Garc?a-Quispes W,Pastor S,Castell J,Biarn?s J,Marcos R,Vel?zquez A


book

Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation.
The Journal of biological chemistry285(24)18309-18(2010 Jun)
McMahon M,Ayll?n V,Panov KI,O'Connor R