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GTF2A1L cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol GTF2A1L
Entrez Gene ID 11036
Full Name general transcription factor IIA subunit 1 like
Synonyms ALF
General protein information
Preferred Names

general transcription factor IIA subunit 1 like

Names

TFIIA-alpha and beta-like factor
GTF2A1-like factor
TFIIA large subunit isoform ALF
TFIIA-alpha/beta-like factor
general transcription factor II A, 1-like factor
general transcription factor IIA 1-like
testis secretory sperm-binding protein Li 230m
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

2

2p16.3
Summary The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Mar 2014].
Disorder MIM:

605358


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_006872.4 NP_006863.2 TFIIA-alpha and beta-like factor isoform 1
NM_001193487.2 NP_001180416.1 TFIIA-alpha and beta-like factor isoform 2
NM_006872.5 NP_006863.2 TFIIA-alpha and beta-like factor isoform 1

Pathways from BioSystems


Homologies


Danio rerio (zebrafish) gtf2a1l NP_001070039.1
Xenopus tropicalis (tropical clawed frog) gtf2a1l NP_001039213.1
Rattus norvegicus (Norway rat) Gtf2a1l NP_001012136.1
Canis lupus familiaris (dog) GTF2A1L NP_001191772.1
Mus musculus (house mouse) Gtf2a1l NP_076119.2
Gallus gallus (chicken) GTF2A1L NP_001191795.1
Homo sapiens (human) GTF2A1L NP_006863.2
Pan troglodytes (chimpanzee) GTF2A1L NP_001191755.1

Gene Ontology


Bibliography

Related articles in PubMed

Association of single nucleotide polymorphisms in the USF1, GTF2A1L and OR2W3 genes with non-obstructive azoospermia in the Chinese population.
Zhang Y, He XJ, Song B, Ye L, Xie XS, Ruan J, Zhou FS, Zuo XB, Cao YX, Du WD
Journal of assisted reproduction and genetics32(1)95-101(2015 Jan)

Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Swaminathan S, Huentelman MJ, Corneveaux JJ, Myers AJ, Faber KM, Foroud T, Mayeux R, Shen L, Kim S, Turk M, Hardy J, Reiman EM, Saykin AJ,
PloS one7(12)e50640(2012)

Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3.
Chen ZJ, Zhao H, He L, Shi Y, Qin Y, Shi Y, Li Z, You L, Zhao J, Liu J, Liang X, Zhao X, Zhao J, Sun Y, Zhang B, Jiang H, Zhao D, Bian Y, Gao X, Geng L, Li Y, Zhu D, Sun X, Xu JE, Hao C, Ren CE, Zhang Y, Chen S, Zhang W, Yang A, Yan J, Li Y, Ma J, Zhao Y
Nature genetics43(1)55-9(2011 Jan)

Regulatory factor interactions and somatic silencing of the germ cell-specific ALF gene.
Kim M, Li D, Cui Y, Mueller K, Chears WC, DeJong J
The Journal of biological chemistry281(45)34288-98(2006 Nov)

Transcription Factor IIA tau is associated with undifferentiated cells and its gene expression is repressed in primary neurons at the chromatin level in vivo.
Howe ML, Mehmud ZF, Saha S, Buratovich M, Stutius EA, Schmidt HD, Lenon AL, Reddicks C, Ivanov GS, Przyborski SA, Ozer JS
Stem cells and development15(2)175-90(2006 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results provided a new insight into susceptibility of USF1 variant with male infertility. rs11204546 of OR2W3 and rs11677854 of GTF2A1L might be additional valuable molecular predictive markers
Title: Association of single nucleotide polymorphisms in the USF1, GTF2A1L and OR2W3 genes with non-obstructive azoospermia in the Chinese population.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

TFIIA tau is associated with undifferentiated cells during development, yet is down-regulated at the chromatin level upon cellular differentiation.
Title: Transcription Factor IIA tau is associated with undifferentiated cells and its gene expression is repressed in primary neurons at the chromatin level in vivo.

Results identified ALF as a human spermatogenesis related gene, the abnormal expression of ALF might be the partial cause for human infertility.
Title: Involvement of ALF in human spermatogenesis and male infertility.

A unique CpG-specific methylation pattern at the ALF promoter precedes expression in pachytene spermatocytes.
Title: Regulation of ALF gene expression in somatic and male germ line tissues involves partial and site-specific patterns of methylation.

The following GTF2A1L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GTF2A1L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu12969 NM_006872.5
Latest version!		 Homo sapiens general transcription factor IIA subunit 1 like (GTF2A1L), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
OHu12972 NM_001193487.2
Latest version!		 Homo sapiens general transcription factor IIA subunit 1 like (GTF2A1L), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
View Old Accession Versions >>
OHu12969 NM_006872.4 Homo sapiens general transcription factor IIA subunit 1 like (GTF2A1L), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu12969
Clone ID Related Accession (Same CDS sequence) NM_006872.4 , NM_006872.5
Accession Version NM_006872.4 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1437bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-02
Organism Homo sapiens(human)
Product TFIIA-alpha and beta-like factor isoform 1
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY049561.1, AC073082.6, BC025991.1 and BG207854.1. On Mar 12, 2014 this sequence version replaced NM_006872.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM005643.1, BC025991.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGCCTGCC TCAACCCGGT GCCTAAACTC TACAGATCTG TAATTGAAGA TGTAATTGAA 
GGAGTTCGGA ATCTATTTGC TGAAGAAGGT ATAGAGGAAC AAGTTTTAAA AGACTTGAAG 
CAGCTCTGGG AAACCAAGGT TTTGCAGTCT AAAGCAACAG AAGACTTCTT CAGAAATAGC 
ATCCAATCAC CTCTGTTTAC TCTTCAGTTG CCGCACAGCT TGCACCAAAC ATTGCAATCG 
TCAACAGCAT CATTAGTTAT TCCTGCTGGT AGAACTCTTC CAAGTTTTAC CACAGCAGAA 
CTGGGCACTT CAAACTCCAG TGCAAACTTT ACTTTTCCTG GTTATCCCAT TCATGTACCA 
GCAGGTGTGA CACTACAGAC TGTATCTGGT CACCTTTATA AAGTCAATGT ACCAATTATG 
GTGACAGAGA CTTCTGGAAG AGCAGGTATT CTTCAGCATC CAATTCAGCA AGTATTTCAA 
CAGCTTGGCC AGCCTTCAGT AATACAAACT AGTGTTCCAC AATTGAATCC ATGGTCTCTT 
CAAGCAACTA CTGAAAAATC ACAGAGAATT GAAACCGTGC TACAGCAACC CGCAATTCTA 
CCTTCTGGGC CAGTAGATAG GAAACACTTA GAAAATGCCA CCAGTGATAT ACTTGTATCT 
CCTGGAAATG AGCATAAAAT CGTGCCTGAA GCTTTGTTGT GTCATCAGGA AAGTTCTCAC 
TATATCAGTC TTCCAGGTGT TGTATTTTCT CCACAGGTCT CTCAAACAAA TTCTAATGTG 
GAGTCAGTGC TCAGTGGTTC AGCTAGCATG GCTCAAAATC TGCATGATGA GTCCCTCTCC 
ACAAGCCCTC ATGGGGCTCT CCACCAGCAC GTGACTGATA TTCAGCTTCA TATTCTTAAA 
AATAGGATGT ATGGATGTGA TTCTGTAAAG CAACCAAGAA ATATAGAGGA ACCCAGCAAC 
ATACCTGTAT CAGAGAAGGA TTCTAATTCT CAGGTGGATT TAAGCATTCG GGTTACTGAT 
GATGATATTG GTGAAATAAT TCAAGTAGAT GGAAGCGGTG ATACATCTTC CAATGAAGAA 
ATAGGAAGTA CAAGAGATGC AGATGAGAAT GAATTTCTAG GGAATATTGA CGGGGGAGAT 
CTGAAGGTAC CTGAAGAAGA AGCTGACAGT ATTTCAAATG AGGATTCAGC CACAAACAGT 
AGTGATAATG AAGACCCTCA AGTAAACATT GTAGAAGAGG ACCCTTTAAA TTCTGGAGAT 
GATGTTAGTG AACAGGATGT GCCAGACCTG TTTGACACGG ATAATGTTAT TGTCTGTCAG 
TATGATAAGA TTCATCGAAG CAAGAACAAA TGGAAATTCT ATTTGAAAGA TGGTGTTATG 
TGTTTTGGAG GGAGAGACTA TGTATTTGCA AAAGCCATTG GTGATGCAGA GTGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_006863.2
CDS96..1532
Translation

Target ORF information:

RefSeq Version NM_006872.4
Organism Homo sapiens(human)
Definition Homo sapiens general transcription factor IIA subunit 1 like (GTF2A1L), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_006872.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGCCTGCC TCAACCCGGT GCCTAAACTC TACAGATCTG TAATTGAAGA TGTAATTGAA 
GGAGTTCGGA ATCTATTTGC TGAAGAAGGT ATAGAGGAAC AAGTTTTAAA AGACTTGAAG 
CAGCTCTGGG AAACCAAGGT TTTGCAGTCT AAAGCAACAG AAGACTTCTT CAGAAATAGC 
ATCCAATCAC CTCTGTTTAC TCTTCAGTTG CCGCACAGCT TGCACCAAAC ATTGCAATCG 
TCAACAGCAT CATTAGTTAT TCCTGCTGGT AGAACTCTTC CAAGTTTTAC CACAGCAGAA 
CTGGGCACTT CAAACTCCAG TGCAAACTTT ACTTTTCCTG GTTATCCCAT TCATGTACCA 
GCAGGTGTGA CACTACAGAC TGTATCTGGT CACCTTTATA AAGTCAATGT ACCAATTATG 
GTGACAGAGA CTTCTGGAAG AGCAGGTATT CTTCAGCATC CAATTCAGCA AGTATTTCAA 
CAGCTTGGCC AGCCTTCAGT AATACAAACT AGTGTTCCAC AATTGAATCC ATGGTCTCTT 
CAAGCAACTA CTGAAAAATC ACAGAGAATT GAAACCGTGC TACAGCAACC CGCAATTCTA 
CCTTCTGGGC CAGTAGATAG GAAACACTTA GAAAATGCCA CCAGTGATAT ACTTGTATCT 
CCTGGAAATG AGCATAAAAT CGTGCCTGAA GCTTTGTTGT GTCATCAGGA AAGTTCTCAC 
TATATCAGTC TTCCAGGTGT TGTATTTTCT CCACAGGTCT CTCAAACAAA TTCTAATGTG 
GAGTCAGTGC TCAGTGGTTC AGCTAGCATG GCTCAAAATC TGCATGATGA GTCCCTCTCC 
ACAAGCCCTC ATGGGGCTCT CCACCAGCAC GTGACTGATA TTCAGCTTCA TATTCTTAAA 
AATAGGATGT ATGGATGTGA TTCTGTAAAG CAACCAAGAA ATATAGAGGA ACCCAGCAAC 
ATACCTGTAT CAGAGAAGGA TTCTAATTCT CAGGTGGATT TAAGCATTCG GGTTACTGAT 
GATGATATTG GTGAAATAAT TCAAGTAGAT GGAAGCGGTG ATACATCTTC CAATGAAGAA 
ATAGGAAGTA CAAGAGATGC AGATGAGAAT GAATTTCTAG GGAATATTGA CGGGGGAGAT 
CTGAAGGTAC CTGAAGAAGA AGCTGACAGT ATTTCAAATG AGGATTCAGC CACAAACAGT 
AGTGATAATG AAGACCCTCA AGTAAACATT GTAGAAGAGG ACCCTTTAAA TTCTGGAGAT 
GATGTTAGTG AACAGGATGT GCCAGACCTG TTTGACACGG ATAATGTTAT TGTCTGTCAG 
TATGATAAGA TTCATCGAAG CAAGAACAAA TGGAAATTCT ATTTGAAAGA TGGTGTTATG 
TGTTTTGGAG GGAGAGACTA TGTATTTGCA AAAGCCATTG GTGATGCAGA GTGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu12969
Clone ID Related Accession (Same CDS sequence) NM_006872.4 , NM_006872.5
Accession Version NM_006872.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1437bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-01
Organism Homo sapiens(human)
Product TFIIA-alpha and beta-like factor isoform 1
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC025991.1 and BG207854.1. On Nov 22, 2018 this sequence version replaced NM_006872.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223350.1, SRR5189667.205351.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000403751.8/ ENSP00000384597.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGCCTGCC TCAACCCGGT GCCTAAACTC TACAGATCTG TAATTGAAGA TGTAATTGAA 
GGAGTTCGGA ATCTATTTGC TGAAGAAGGT ATAGAGGAAC AAGTTTTAAA AGACTTGAAG 
CAGCTCTGGG AAACCAAGGT TTTGCAGTCT AAAGCAACAG AAGACTTCTT CAGAAATAGC 
ATCCAATCAC CTCTGTTTAC TCTTCAGTTG CCGCACAGCT TGCACCAAAC ATTGCAATCG 
TCAACAGCAT CATTAGTTAT TCCTGCTGGT AGAACTCTTC CAAGTTTTAC CACAGCAGAA 
CTGGGCACTT CAAACTCCAG TGCAAACTTT ACTTTTCCTG GTTATCCCAT TCATGTACCA 
GCAGGTGTGA CACTACAGAC TGTATCTGGT CACCTTTATA AAGTCAATGT ACCAATTATG 
GTGACAGAGA CTTCTGGAAG AGCAGGTATT CTTCAGCATC CAATTCAGCA AGTATTTCAA 
CAGCTTGGCC AGCCTTCAGT AATACAAACT AGTGTTCCAC AATTGAATCC ATGGTCTCTT 
CAAGCAACTA CTGAAAAATC ACAGAGAATT GAAACCGTGC TACAGCAACC CGCAATTCTA 
CCTTCTGGGC CAGTAGATAG GAAACACTTA GAAAATGCCA CCAGTGATAT ACTTGTATCT 
CCTGGAAATG AGCATAAAAT CGTGCCTGAA GCTTTGTTGT GTCATCAGGA AAGTTCTCAC 
TATATCAGTC TTCCAGGTGT TGTATTTTCT CCACAGGTCT CTCAAACAAA TTCTAATGTG 
GAGTCAGTGC TCAGTGGTTC AGCTAGCATG GCTCAAAATC TGCATGATGA GTCCCTCTCC 
ACAAGCCCTC ATGGGGCTCT CCACCAGCAC GTGACTGATA TTCAGCTTCA TATTCTTAAA 
AATAGGATGT ATGGATGTGA TTCTGTAAAG CAACCAAGAA ATATAGAGGA ACCCAGCAAC 
ATACCTGTAT CAGAGAAGGA TTCTAATTCT CAGGTGGATT TAAGCATTCG GGTTACTGAT 
GATGATATTG GTGAAATAAT TCAAGTAGAT GGAAGCGGTG ATACATCTTC CAATGAAGAA 
ATAGGAAGTA CAAGAGATGC AGATGAGAAT GAATTTCTAG GGAATATTGA CGGGGGAGAT 
CTGAAGGTAC CTGAAGAAGA AGCTGACAGT ATTTCAAATG AGGATTCAGC CACAAACAGT 
AGTGATAATG AAGACCCTCA AGTAAACATT GTAGAAGAGG ACCCTTTAAA TTCTGGAGAT 
GATGTTAGTG AACAGGATGT GCCAGACCTG TTTGACACGG ATAATGTTAT TGTCTGTCAG 
TATGATAAGA TTCATCGAAG CAAGAACAAA TGGAAATTCT ATTTGAAAGA TGGTGTTATG 
TGTTTTGGAG GGAGAGACTA TGTATTTGCA AAAGCCATTG GTGATGCAGA GTGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_006863.2
CDS20..1456
Translation

Target ORF information:

RefSeq Version NM_006872.5
Organism Homo sapiens(human)
Definition Homo sapiens general transcription factor IIA subunit 1 like (GTF2A1L), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_006872.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGCCTGCC TCAACCCGGT GCCTAAACTC TACAGATCTG TAATTGAAGA TGTAATTGAA 
GGAGTTCGGA ATCTATTTGC TGAAGAAGGT ATAGAGGAAC AAGTTTTAAA AGACTTGAAG 
CAGCTCTGGG AAACCAAGGT TTTGCAGTCT AAAGCAACAG AAGACTTCTT CAGAAATAGC 
ATCCAATCAC CTCTGTTTAC TCTTCAGTTG CCGCACAGCT TGCACCAAAC ATTGCAATCG 
TCAACAGCAT CATTAGTTAT TCCTGCTGGT AGAACTCTTC CAAGTTTTAC CACAGCAGAA 
CTGGGCACTT CAAACTCCAG TGCAAACTTT ACTTTTCCTG GTTATCCCAT TCATGTACCA 
GCAGGTGTGA CACTACAGAC TGTATCTGGT CACCTTTATA AAGTCAATGT ACCAATTATG 
GTGACAGAGA CTTCTGGAAG AGCAGGTATT CTTCAGCATC CAATTCAGCA AGTATTTCAA 
CAGCTTGGCC AGCCTTCAGT AATACAAACT AGTGTTCCAC AATTGAATCC ATGGTCTCTT 
CAAGCAACTA CTGAAAAATC ACAGAGAATT GAAACCGTGC TACAGCAACC CGCAATTCTA 
CCTTCTGGGC CAGTAGATAG GAAACACTTA GAAAATGCCA CCAGTGATAT ACTTGTATCT 
CCTGGAAATG AGCATAAAAT CGTGCCTGAA GCTTTGTTGT GTCATCAGGA AAGTTCTCAC 
TATATCAGTC TTCCAGGTGT TGTATTTTCT CCACAGGTCT CTCAAACAAA TTCTAATGTG 
GAGTCAGTGC TCAGTGGTTC AGCTAGCATG GCTCAAAATC TGCATGATGA GTCCCTCTCC 
ACAAGCCCTC ATGGGGCTCT CCACCAGCAC GTGACTGATA TTCAGCTTCA TATTCTTAAA 
AATAGGATGT ATGGATGTGA TTCTGTAAAG CAACCAAGAA ATATAGAGGA ACCCAGCAAC 
ATACCTGTAT CAGAGAAGGA TTCTAATTCT CAGGTGGATT TAAGCATTCG GGTTACTGAT 
GATGATATTG GTGAAATAAT TCAAGTAGAT GGAAGCGGTG ATACATCTTC CAATGAAGAA 
ATAGGAAGTA CAAGAGATGC AGATGAGAAT GAATTTCTAG GGAATATTGA CGGGGGAGAT 
CTGAAGGTAC CTGAAGAAGA AGCTGACAGT ATTTCAAATG AGGATTCAGC CACAAACAGT 
AGTGATAATG AAGACCCTCA AGTAAACATT GTAGAAGAGG ACCCTTTAAA TTCTGGAGAT 
GATGTTAGTG AACAGGATGT GCCAGACCTG TTTGACACGG ATAATGTTAT TGTCTGTCAG 
TATGATAAGA TTCATCGAAG CAAGAACAAA TGGAAATTCT ATTTGAAAGA TGGTGTTATG 
TGTTTTGGAG GGAGAGACTA TGTATTTGCA AAAGCCATTG GTGATGCAGA GTGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu12972
Clone ID Related Accession (Same CDS sequence) NM_001193487.2
Accession Version NM_001193487.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1335bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-02
Organism Homo sapiens(human)
Product TFIIA-alpha and beta-like factor isoform 2
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY049561.1, AK302220.1 and BG207854.1. On Mar 12, 2014 this sequence version replaced NM_001193487.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCCTGCC TCAACCCGGT GCTCTGGGAA ACCAAGGTTT TGCAGTCTAA AGCAACAGAA 
GACTTCTTCA GAAATAGCAT CCAATCACCT CTGTTTACTC TTCAGTTGCC GCACAGCTTG 
CACCAAACAT TGCAATCGTC AACAGCATCA TTAGTTATTC CTGCTGGTAG AACTCTTCCA 
AGTTTTACCA CAGCAGAACT GGGCACTTCA AACTCCAGTG CAAACTTTAC TTTTCCTGGT 
TATCCCATTC ATGTACCAGC AGGTGTGACA CTACAGACTG TATCTGGTCA CCTTTATAAA 
GTCAATGTAC CAATTATGGT GACAGAGACT TCTGGAAGAG CAGGTATTCT TCAGCATCCA 
ATTCAGCAAG TATTTCAACA GCTTGGCCAG CCTTCAGTAA TACAAACTAG TGTTCCACAA 
TTGAATCCAT GGTCTCTTCA AGCAACTACT GAAAAATCAC AGAGAATTGA AACCGTGCTA 
CAGCAACCCG CAATTCTACC TTCTGGGCCA GTAGATAGGA AACACTTAGA AAATGCCACC 
AGTGATATAC TTGTATCTCC TGGAAATGAG CATAAAATCG TGCCTGAAGC TTTGTTGTGT 
CATCAGGAAA GTTCTCACTA TATCAGTCTT CCAGGTGTTG TATTTTCTCC ACAGGTCTCT 
CAAACAAATT CTAATGTGGA GTCAGTGCTC AGTGGTTCAG CTAGCATGGC TCAAAATCTG 
CATGATGAGT CCCTCTCCAC AAGCCCTCAT GGGGCTCTCC ACCAGCACGT GACTGATATT 
CAGCTTCATA TTCTTAAAAA TAGGATGTAT GGATGTGATT CTGTAAAGCA ACCAAGAAAT 
ATAGAGGAAC CCAGCAACAT ACCTGTATCA GAGAAGGATT CTAATTCTCA GGTGGATTTA 
AGCATTCGGG TTACTGATGA TGATATTGGT GAAATAATTC AAGTAGATGG AAGCGGTGAT 
ACATCTTCCA ATGAAGAAAT AGGAAGTACA AGAGATGCAG ATGAGAATGA ATTTCTAGGG 
AATATTGACG GGGGAGATCT GAAGGTACCT GAAGAAGAAG CTGACAGTAT TTCAAATGAG 
GATTCAGCCA CAAACAGTAG TGATAATGAA GACCCTCAAG TAAACATTGT AGAAGAGGAC 
CCTTTAAATT CTGGAGATGA TGTTAGTGAA CAGGATGTGC CAGACCTGTT TGACACGGAT 
AATGTTATTG TCTGTCAGTA TGATAAGATT CATCGAAGCA AGAACAAATG GAAATTCTAT 
TTGAAAGATG GTGTTATGTG TTTTGGAGGG AGAGACTATG TATTTGCAAA AGCCATTGGT 
GATGCAGAGT GGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001180416.1
CDS96..1430
Translation

Target ORF information:

RefSeq Version NM_001193487.2
Organism Homo sapiens(human)
Definition Homo sapiens general transcription factor IIA subunit 1 like (GTF2A1L), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001193487.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCCTGCC TCAACCCGGT GCTCTGGGAA ACCAAGGTTT TGCAGTCTAA AGCAACAGAA 
GACTTCTTCA GAAATAGCAT CCAATCACCT CTGTTTACTC TTCAGTTGCC GCACAGCTTG 
CACCAAACAT TGCAATCGTC AACAGCATCA TTAGTTATTC CTGCTGGTAG AACTCTTCCA 
AGTTTTACCA CAGCAGAACT GGGCACTTCA AACTCCAGTG CAAACTTTAC TTTTCCTGGT 
TATCCCATTC ATGTACCAGC AGGTGTGACA CTACAGACTG TATCTGGTCA CCTTTATAAA 
GTCAATGTAC CAATTATGGT GACAGAGACT TCTGGAAGAG CAGGTATTCT TCAGCATCCA 
ATTCAGCAAG TATTTCAACA GCTTGGCCAG CCTTCAGTAA TACAAACTAG TGTTCCACAA 
TTGAATCCAT GGTCTCTTCA AGCAACTACT GAAAAATCAC AGAGAATTGA AACCGTGCTA 
CAGCAACCCG CAATTCTACC TTCTGGGCCA GTAGATAGGA AACACTTAGA AAATGCCACC 
AGTGATATAC TTGTATCTCC TGGAAATGAG CATAAAATCG TGCCTGAAGC TTTGTTGTGT 
CATCAGGAAA GTTCTCACTA TATCAGTCTT CCAGGTGTTG TATTTTCTCC ACAGGTCTCT 
CAAACAAATT CTAATGTGGA GTCAGTGCTC AGTGGTTCAG CTAGCATGGC TCAAAATCTG 
CATGATGAGT CCCTCTCCAC AAGCCCTCAT GGGGCTCTCC ACCAGCACGT GACTGATATT 
CAGCTTCATA TTCTTAAAAA TAGGATGTAT GGATGTGATT CTGTAAAGCA ACCAAGAAAT 
ATAGAGGAAC CCAGCAACAT ACCTGTATCA GAGAAGGATT CTAATTCTCA GGTGGATTTA 
AGCATTCGGG TTACTGATGA TGATATTGGT GAAATAATTC AAGTAGATGG AAGCGGTGAT 
ACATCTTCCA ATGAAGAAAT AGGAAGTACA AGAGATGCAG ATGAGAATGA ATTTCTAGGG 
AATATTGACG GGGGAGATCT GAAGGTACCT GAAGAAGAAG CTGACAGTAT TTCAAATGAG 
GATTCAGCCA CAAACAGTAG TGATAATGAA GACCCTCAAG TAAACATTGT AGAAGAGGAC 
CCTTTAAATT CTGGAGATGA TGTTAGTGAA CAGGATGTGC CAGACCTGTT TGACACGGAT 
AATGTTATTG TCTGTCAGTA TGATAAGATT CATCGAAGCA AGAACAAATG GAAATTCTAT 
TTGAAAGATG GTGTTATGTG TTTTGGAGGG AGAGACTATG TATTTGCAAA AGCCATTGGT 
GATGCAGAGT GGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Association of single nucleotide polymorphisms in the USF1, GTF2A1L and OR2W3 genes with non-obstructive azoospermia in the Chinese population.
Journal of assisted reproduction and genetics32(1)95-101(2015 Jan)
Zhang Y,He XJ,Song B,Ye L,Xie XS,Ruan J,Zhou FS,Zuo XB,Cao YX,Du WD


book

Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
PloS one7(12)e50640(2012)
Swaminathan S,Huentelman MJ,Corneveaux JJ,Myers AJ,Faber KM,Foroud T,Mayeux R,Shen L,Kim S,Turk M,Hardy J,Reiman EM,Saykin AJ,


book

Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3.
Nature genetics43(1)55-9(2011 Jan)
Chen ZJ,Zhao H,He L,Shi Y,Qin Y,Shi Y,Li Z,You L,Zhao J,Liu J,Liang X,Zhao X,Zhao J,Sun Y,Zhang B,Jiang H,Zhao D,Bian Y,Gao X,Geng L,Li Y,Zhu D,Sun X,Xu JE,Hao C,Ren CE,Zhang Y,Chen S,Zhang W,Yang A,Yan J,Li Y,Ma J,Zhao Y


book

Regulatory factor interactions and somatic silencing of the germ cell-specific ALF gene.
The Journal of biological chemistry281(45)34288-98(2006 Nov)
Kim M,Li D,Cui Y,Mueller K,Chears WC,DeJong J


book

Transcription Factor IIA tau is associated with undifferentiated cells and its gene expression is repressed in primary neurons at the chromatin level in vivo.
Stem cells and development15(2)175-90(2006 Apr)
Howe ML,Mehmud ZF,Saha S,Buratovich M,Stutius EA,Schmidt HD,Lenon AL,Reddicks C,Ivanov GS,Przyborski SA,Ozer JS