• English
  • Sign In
    Please Sign In
    Sign In
    New to GenScript?
    Register
  • Contact Us
×
Contact us now: +1-877-436-7274

SNRNP35 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol SNRNP35
Entrez Gene ID 11066
Full Name small nuclear ribonucleoprotein U11/U12 subunit 35
Synonyms HM-1,U1SNRNPBP
General protein information
Preferred Names

small nuclear ribonucleoprotein U11/U12 subunit 35

Names

U11/U12 small nuclear ribonucleoprotein 35 kDa protein
U1 snRNP-binding protein homolog
U11/U12 snRNP 35 kDa protein
U11/U12 snRNP 35K
U11/U12-35K
protein HM-1
small nuclear ribonucleoprotein 35kDa (U11/U12)
small nuclear ribonucleoprotein, U11/U12 35kDa subunit
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

12

12q24.31
Summary The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant. [provided by RefSeq, Aug 2013].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_180699.3 NP_851030.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform b
NM_022717.3 NP_073208.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform a
XM_006719204.2 XP_006719267.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1
XM_017018724.1 XP_016874213.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X2
XM_017018724.2 XP_016874213.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1
XM_006719204.3 XP_006719267.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X3
XM_011537780.2 XP_011536082.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1
NM_022717.4 NP_073208.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform a
XM_006719204.4 XP_006719267.1 U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X2

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) SNRNP35 XP_509463.2
Canis lupus familiaris (dog) SNRNP35 XP_534648.2
Mus musculus (house mouse) Snrnp35 NP_083808.1
Rattus norvegicus (Norway rat) Snrnp35 NP_001014149.1
LOC702933 XP_001089715.1
Xenopus tropicalis (tropical clawed frog) snrnp35 NP_001136383.1
Homo sapiens (human) SNRNP35 NP_851030.1
Danio rerio (zebrafish) snrnp35 NP_001025412.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP012250 XP_320292.3
Oryza sativa (rice) Os09g0513700 NP_001063653.1
Bos taurus (cattle) SNRNP35 NP_001069024.1
Gallus gallus (chicken) SNRNP35 NP_001264104.1
Arabidopsis thaliana (thale cress) AT2G43370 NP_850395.1

Gene Ontology


Bibliography

Related articles in PubMed

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
Rietveld CA, Esko T, Davies G, Pers TH, Turley P, Benyamin B, Chabris CF, Emilsson V, Johnson AD, Lee JJ, de Leeuw C, Marioni RE, Medland SE, Miller MB, Rostapshova O, van der Lee SJ, Vinkhuyzen AA, Amin N, Conley D, Derringer J, van Duijn CM, Fehrmann R, Franke L, Glaeser EL, Hansell NK, Hayward C, Iacono WG, Ibrahim-Verbaas C, Jaddoe V, Karjalainen J, Laibson D, Lichtenstein P, Liewald DC, Magnusson PK, Martin NG, McGue M, McMahon G, Pedersen NL, Pinker S, Porteous DJ, Posthuma D, Rivadeneira F, Smith BH, Starr JM, Tiemeier H, Timpson NJ, Trzaskowski M, Uitterlinden AG, Verhulst FC, Ward ME, Wright MJ, Davey Smith G, Deary IJ, Johannesson M, Plomin R, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD
Proceedings of the National Academy of Sciences of the United States of America111(38)13790-4(2014 Sep)

Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
White GE, McNeill E, Christou I, Channon KM, Greaves DR
Molecular pharmacology80(2)328-36(2011 Aug)

Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis.
Fertig N, Domsic RT, Rodriguez-Reyna T, Kuwana M, Lucas M, Medsger TA Jr, Feghali-Bostwick CA
Arthritis and rheumatism61(7)958-65(2009 Jul)

Minor spliceosome components are predominantly localized in the nucleus.
Pessa HK, Will CL, Meng X, Schneider C, Watkins NJ, Per?l? N, Nymark M, Turunen JJ, L?hrmann R, Frilander MJ
Proceedings of the National Academy of Sciences of the United States of America105(25)8655-60(2008 Jun)

The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.
Will CL, Schneider C, Hossbach M, Urlaub H, Rauhut R, Elbashir S, Tuschl T, L?hrmann R
RNA (New York, N.Y.)10(6)929-41(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

An Fc-fusion protein of 35kDa with a modified human immunoglobulin IgG1 Fc domain is capable of inhibiting CC chemokine-induced calcium flux, chemotaxis, and beta-arrestin recruitment in primary macrophages and transfected cells.
Title: Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.

Anti-U11/U12 RNP antibodies are present in the sera of approximately 3% of patients with systemic sclerosis and are a marker for lung fibrosis, which is often severe.
Title: Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis.

The following SNRNP35 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNRNP35 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu00502 NM_022717.4
Latest version!		 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $99.50-$139.30
$199.00
OHu07541 NM_180699.3
Latest version!		 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu00502 XM_006719204.4
Latest version!		 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $99.50-$139.30
$199.00
OHu07541 XM_017018724.2
Latest version!		 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu46268 XM_011537780.2
Latest version!		 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $99.50-$139.30
$199.00
View Old Accession Versions >>
OHu07541 XM_017018724.1 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu00502 XM_006719204.2 Homo sapiens small nuclear ribonucleoprotein 35kDa (U11/U12) (SNRNP35), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $99.50-$139.30
$199.00
OHu00502 NM_022717.3 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $99.50-$139.30
$199.00
OHu00502 XM_006719204.3 Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $99.50-$139.30
$199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu00502
Clone ID Related Accession (Same CDS sequence) NM_022717.3 , XM_006719204.2 , XM_006719204.3 , NM_022717.4 , XM_006719204.4
Accession Version NM_022717.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-06-29
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform a
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM714052.1 and BC047678.1. On Aug 21, 2013 this sequence version replaced NM_022717.2. Transcript Variant: This variant (2) encodes the shorter isoform (a). ##Evidence-Data-START## Transcript exon combination :: BM714052.1, BC028485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_073208.1
CDS117..857
Translation

Target ORF information:

RefSeq Version NM_022717.3
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_022717.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu00502
Clone ID Related Accession (Same CDS sequence) NM_022717.3 , XM_006719204.2 , XM_006719204.3 , NM_022717.4 , XM_006719204.4
Accession Version NM_022717.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-11-18
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform a
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM714052.1, BC047678.1 and AC145423.8. On May 17, 2019 this sequence version replaced NM_022717.3. Transcript Variant: This variant (2) encodes the shorter isoform (a). ##Evidence-Data-START## Transcript exon combination :: SRR7410570.510716.1, SRR5189661.165690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000526639.3/ ENSP00000432595.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_073208.1
CDS82..822
Translation

Target ORF information:

RefSeq Version NM_022717.4
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_022717.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07541
Clone ID Related Accession (Same CDS sequence) NM_180699.3 , XM_017018724.1 , XM_017018724.2
Accession Version NM_180699.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 756bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-11-15
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform b
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC047678.1. On Aug 21, 2013 this sequence version replaced NM_180699.2. Transcript Variant: This variant (3) includes an alternate exon and initiates translation at an alternate start codon, compared to variant 2. The full extent of the 5' UTR of this variant has not been determined. The encoded isoform (b) has a longer N-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.232297.1, SRR1660807.140783.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAACCAG CTAACATGAA CGATTGGATG CCCATCGCCA AGGAGTATGA TCCACTCAAA 
GCGGGCAGCA TTGATGGCAC CGATGAAGAC CCACACGACC GCGCGGTCTG GAGGGCAATG 
CTGGCACGAT ATGTCCCCAA CAAAGGTGTC ATAGGAGATC CCCTCCTCAC CCTGTTTGTG 
GCCAGACTAA ACTTGCAGAC CAAGGAGGAC AAATTAAAGG AAGTCTTTTC CCGCTATGGT 
GACATCCGGC GGCTTCGGCT GGTCAGGGAC TTGGTCACAG GTTTTTCAAA GGGCTACGCC 
TTCATCGAAT ACAAGGAGGA GCGTGCCGTG ATCAAAGCTT ACCGAGATGC TGATGGCCTG 
GTTATTGACC AGCATGAGAT ATTTGTGGAC TACGAGCTGG AAAGGACTCT CAAAGGGTGG 
ATCCCTCGGC GACTTGGAGG CGGTCTTGGG GGAAAAAAGG AGTCTGGGCA ACTGAGATTT 
GGGGGACGGG ACCGGCCTTT TCGAAAACCT ATTAACTTGC CAGTTGTTAA AAACGACCTC 
TATAGAGAGG GAAAACGGGA AAGGCGGGAG CGATCTCGAT CCCGAGAAAG ACACTGGGAC 
TCGAGGACAA GGGATCGAGA CCATGACAGG GGCCGGGAGA AGAGATGGCA AGAAAGAGAG 
CCGACCAGGG TGTGGCCCGA CAATGACTGG GAGAGAGAGA GGGACTTCAG AGATGACAGG 
ATCAAGGGGA GGGAGAAGAA GGAAAGAGGC AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851030.1
CDS186..941
Translation

Target ORF information:

RefSeq Version NM_180699.3
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_180699.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAACCAG CTAACATGAA CGATTGGATG CCCATCGCCA AGGAGTATGA TCCACTCAAA 
GCGGGCAGCA TTGATGGCAC CGATGAAGAC CCACACGACC GCGCGGTCTG GAGGGCAATG 
CTGGCACGAT ATGTCCCCAA CAAAGGTGTC ATAGGAGATC CCCTCCTCAC CCTGTTTGTG 
GCCAGACTAA ACTTGCAGAC CAAGGAGGAC AAATTAAAGG AAGTCTTTTC CCGCTATGGT 
GACATCCGGC GGCTTCGGCT GGTCAGGGAC TTGGTCACAG GTTTTTCAAA GGGCTACGCC 
TTCATCGAAT ACAAGGAGGA GCGTGCCGTG ATCAAAGCTT ACCGAGATGC TGATGGCCTG 
GTTATTGACC AGCATGAGAT ATTTGTGGAC TACGAGCTGG AAAGGACTCT CAAAGGGTGG 
ATCCCTCGGC GACTTGGAGG CGGTCTTGGG GGAAAAAAGG AGTCTGGGCA ACTGAGATTT 
GGGGGACGGG ACCGGCCTTT TCGAAAACCT ATTAACTTGC CAGTTGTTAA AAACGACCTC 
TATAGAGAGG GAAAACGGGA AAGGCGGGAG CGATCTCGAT CCCGAGAAAG ACACTGGGAC 
TCGAGGACAA GGGATCGAGA CCATGACAGG GGCCGGGAGA AGAGATGGCA AGAAAGAGAG 
CCGACCAGGG TGTGGCCCGA CAATGACTGG GAGAGAGAGA GGGACTTCAG AGATGACAGG 
ATCAAGGGGA GGGAGAAGAA GGAAAGAGGC AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu00502
Clone ID Related Accession (Same CDS sequence) NM_022717.3 , XM_006719204.2 , XM_006719204.3 , NM_022717.4 , XM_006719204.4
Accession Version XM_006719204.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-03-11
Organism Homo sapiens(Human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006719267.1
Translation

Target ORF information:

RefSeq Version XM_006719204.2
Organism Homo sapiens(Human)
Definition Homo sapiens small nuclear ribonucleoprotein 35kDa (U11/U12) (SNRNP35), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006719204.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu00502
Clone ID Related Accession (Same CDS sequence) NM_022717.3 , XM_006719204.2 , XM_006719204.3 , NM_022717.4 , XM_006719204.4
Accession Version XM_006719204.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006719204.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006719267.1
CDS1300..2040
Translation

Target ORF information:

RefSeq Version XM_006719204.3
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006719204.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu00502
Clone ID Related Accession (Same CDS sequence) NM_022717.3 , XM_006719204.2 , XM_006719204.3 , NM_022717.4 , XM_006719204.4
Accession Version XM_006719204.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006719204.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006719267.1
CDS767..1507
Translation

Target ORF information:

RefSeq Version XM_006719204.4
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006719204.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAACGATT GGATGCCCAT CGCCAAGGAG TATGATCCAC TCAAAGCGGG CAGCATTGAT 
GGCACCGATG AAGACCCACA CGACCGCGCG GTCTGGAGGG CAATGCTGGC ACGATATGTC 
CCCAACAAAG GTGTCATAGG AGATCCCCTC CTCACCCTGT TTGTGGCCAG ACTAAACTTG 
CAGACCAAGG AGGACAAATT AAAGGAAGTC TTTTCCCGCT ATGGTGACAT CCGGCGGCTT 
CGGCTGGTCA GGGACTTGGT CACAGGTTTT TCAAAGGGCT ACGCCTTCAT CGAATACAAG 
GAGGAGCGTG CCGTGATCAA AGCTTACCGA GATGCTGATG GCCTGGTTAT TGACCAGCAT 
GAGATATTTG TGGACTACGA GCTGGAAAGG ACTCTCAAAG GGTGGATCCC TCGGCGACTT 
GGAGGCGGTC TTGGGGGAAA AAAGGAGTCT GGGCAACTGA GATTTGGGGG ACGGGACCGG 
CCTTTTCGAA AACCTATTAA CTTGCCAGTT GTTAAAAACG ACCTCTATAG AGAGGGAAAA 
CGGGAAAGGC GGGAGCGATC TCGATCCCGA GAAAGACACT GGGACTCGAG GACAAGGGAT 
CGAGACCATG ACAGGGGCCG GGAGAAGAGA TGGCAAGAAA GAGAGCCGAC CAGGGTGTGG 
CCCGACAATG ACTGGGAGAG AGAGAGGGAC TTCAGAGATG ACAGGATCAA GGGGAGGGAG 
AAGAAGGAAA GAGGCAAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07541
Clone ID Related Accession (Same CDS sequence) NM_180699.3 , XM_017018724.1 , XM_017018724.2
Accession Version XM_017018724.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 756bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAACCAG CTAACATGAA CGATTGGATG CCCATCGCCA AGGAGTATGA TCCACTCAAA 
GCGGGCAGCA TTGATGGCAC CGATGAAGAC CCACACGACC GCGCGGTCTG GAGGGCAATG 
CTGGCACGAT ATGTCCCCAA CAAAGGTGTC ATAGGAGATC CCCTCCTCAC CCTGTTTGTG 
GCCAGACTAA ACTTGCAGAC CAAGGAGGAC AAATTAAAGG AAGTCTTTTC CCGCTATGGT 
GACATCCGGC GGCTTCGGCT GGTCAGGGAC TTGGTCACAG GTTTTTCAAA GGGCTACGCC 
TTCATCGAAT ACAAGGAGGA GCGTGCCGTG ATCAAAGCTT ACCGAGATGC TGATGGCCTG 
GTTATTGACC AGCATGAGAT ATTTGTGGAC TACGAGCTGG AAAGGACTCT CAAAGGGTGG 
ATCCCTCGGC GACTTGGAGG CGGTCTTGGG GGAAAAAAGG AGTCTGGGCA ACTGAGATTT 
GGGGGACGGG ACCGGCCTTT TCGAAAACCT ATTAACTTGC CAGTTGTTAA AAACGACCTC 
TATAGAGAGG GAAAACGGGA AAGGCGGGAG CGATCTCGAT CCCGAGAAAG ACACTGGGAC 
TCGAGGACAA GGGATCGAGA CCATGACAGG GGCCGGGAGA AGAGATGGCA AGAAAGAGAG 
CCGACCAGGG TGTGGCCCGA CAATGACTGG GAGAGAGAGA GGGACTTCAG AGATGACAGG 
ATCAAGGGGA GGGAGAAGAA GGAAAGAGGC AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016874213.1
CDS1013..1768
Translation

Target ORF information:

RefSeq Version XM_017018724.1
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017018724.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAACCAG CTAACATGAA CGATTGGATG CCCATCGCCA AGGAGTATGA TCCACTCAAA 
GCGGGCAGCA TTGATGGCAC CGATGAAGAC CCACACGACC GCGCGGTCTG GAGGGCAATG 
CTGGCACGAT ATGTCCCCAA CAAAGGTGTC ATAGGAGATC CCCTCCTCAC CCTGTTTGTG 
GCCAGACTAA ACTTGCAGAC CAAGGAGGAC AAATTAAAGG AAGTCTTTTC CCGCTATGGT 
GACATCCGGC GGCTTCGGCT GGTCAGGGAC TTGGTCACAG GTTTTTCAAA GGGCTACGCC 
TTCATCGAAT ACAAGGAGGA GCGTGCCGTG ATCAAAGCTT ACCGAGATGC TGATGGCCTG 
GTTATTGACC AGCATGAGAT ATTTGTGGAC TACGAGCTGG AAAGGACTCT CAAAGGGTGG 
ATCCCTCGGC GACTTGGAGG CGGTCTTGGG GGAAAAAAGG AGTCTGGGCA ACTGAGATTT 
GGGGGACGGG ACCGGCCTTT TCGAAAACCT ATTAACTTGC CAGTTGTTAA AAACGACCTC 
TATAGAGAGG GAAAACGGGA AAGGCGGGAG CGATCTCGAT CCCGAGAAAG ACACTGGGAC 
TCGAGGACAA GGGATCGAGA CCATGACAGG GGCCGGGAGA AGAGATGGCA AGAAAGAGAG 
CCGACCAGGG TGTGGCCCGA CAATGACTGG GAGAGAGAGA GGGACTTCAG AGATGACAGG 
ATCAAGGGGA GGGAGAAGAA GGAAAGAGGC AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07541
Clone ID Related Accession (Same CDS sequence) NM_180699.3 , XM_017018724.1 , XM_017018724.2
Accession Version XM_017018724.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 756bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017018724.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAACCAG CTAACATGAA CGATTGGATG CCCATCGCCA AGGAGTATGA TCCACTCAAA 
GCGGGCAGCA TTGATGGCAC CGATGAAGAC CCACACGACC GCGCGGTCTG GAGGGCAATG 
CTGGCACGAT ATGTCCCCAA CAAAGGTGTC ATAGGAGATC CCCTCCTCAC CCTGTTTGTG 
GCCAGACTAA ACTTGCAGAC CAAGGAGGAC AAATTAAAGG AAGTCTTTTC CCGCTATGGT 
GACATCCGGC GGCTTCGGCT GGTCAGGGAC TTGGTCACAG GTTTTTCAAA GGGCTACGCC 
TTCATCGAAT ACAAGGAGGA GCGTGCCGTG ATCAAAGCTT ACCGAGATGC TGATGGCCTG 
GTTATTGACC AGCATGAGAT ATTTGTGGAC TACGAGCTGG AAAGGACTCT CAAAGGGTGG 
ATCCCTCGGC GACTTGGAGG CGGTCTTGGG GGAAAAAAGG AGTCTGGGCA ACTGAGATTT 
GGGGGACGGG ACCGGCCTTT TCGAAAACCT ATTAACTTGC CAGTTGTTAA AAACGACCTC 
TATAGAGAGG GAAAACGGGA AAGGCGGGAG CGATCTCGAT CCCGAGAAAG ACACTGGGAC 
TCGAGGACAA GGGATCGAGA CCATGACAGG GGCCGGGAGA AGAGATGGCA AGAAAGAGAG 
CCGACCAGGG TGTGGCCCGA CAATGACTGG GAGAGAGAGA GGGACTTCAG AGATGACAGG 
ATCAAGGGGA GGGAGAAGAA GGAAAGAGGC AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016874213.1
CDS1042..1797
Translation

Target ORF information:

RefSeq Version XM_017018724.2
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017018724.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAACCAG CTAACATGAA CGATTGGATG CCCATCGCCA AGGAGTATGA TCCACTCAAA 
GCGGGCAGCA TTGATGGCAC CGATGAAGAC CCACACGACC GCGCGGTCTG GAGGGCAATG 
CTGGCACGAT ATGTCCCCAA CAAAGGTGTC ATAGGAGATC CCCTCCTCAC CCTGTTTGTG 
GCCAGACTAA ACTTGCAGAC CAAGGAGGAC AAATTAAAGG AAGTCTTTTC CCGCTATGGT 
GACATCCGGC GGCTTCGGCT GGTCAGGGAC TTGGTCACAG GTTTTTCAAA GGGCTACGCC 
TTCATCGAAT ACAAGGAGGA GCGTGCCGTG ATCAAAGCTT ACCGAGATGC TGATGGCCTG 
GTTATTGACC AGCATGAGAT ATTTGTGGAC TACGAGCTGG AAAGGACTCT CAAAGGGTGG 
ATCCCTCGGC GACTTGGAGG CGGTCTTGGG GGAAAAAAGG AGTCTGGGCA ACTGAGATTT 
GGGGGACGGG ACCGGCCTTT TCGAAAACCT ATTAACTTGC CAGTTGTTAA AAACGACCTC 
TATAGAGAGG GAAAACGGGA AAGGCGGGAG CGATCTCGAT CCCGAGAAAG ACACTGGGAC 
TCGAGGACAA GGGATCGAGA CCATGACAGG GGCCGGGAGA AGAGATGGCA AGAAAGAGAG 
CCGACCAGGG TGTGGCCCGA CAATGACTGG GAGAGAGAGA GGGACTTCAG AGATGACAGG 
ATCAAGGGGA GGGAGAAGAA GGAAAGAGGC AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu46268
Clone ID Related Accession (Same CDS sequence) XM_011537780.2
Accession Version XM_011537780.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 924bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011537780.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGATAACAC CCTCGTTGCG TGGGAGTAAA ATTTTAAAGG TAAAACAAAC AGGAAACGAG 
CGTCGGCGGC GAATCTGCTG CTACCAATGT AAAGGTCAGG CCGAGGCCGG CGCGGAGAAT 
CTGCTGTCGC CTGCAGCTGC TCGCCTGTCT CCGTCGGAAG GGAGCCCAAG CTTTGCAGAG 
AACATGAACG ATTGGATGCC CATCGCCAAG GAGTATGATC CACTCAAAGC GGGCAGCATT 
GATGGCACCG ATGAAGACCC ACACGACCGC GCGGTCTGGA GGGCAATGCT GGCACGATAT 
GTCCCCAACA AAGGTGTCAT AGGAGATCCC CTCCTCACCC TGTTTGTGGC CAGACTAAAC 
TTGCAGACCA AGGAGGACAA ATTAAAGGAA GTCTTTTCCC GCTATGGTGA CATCCGGCGG 
CTTCGGCTGG TCAGGGACTT GGTCACAGGT TTTTCAAAGG GCTACGCCTT CATCGAATAC 
AAGGAGGAGC GTGCCGTGAT CAAAGCTTAC CGAGATGCTG ATGGCCTGGT TATTGACCAG 
CATGAGATAT TTGTGGACTA CGAGCTGGAA AGGACTCTCA AAGGGTGGAT CCCTCGGCGA 
CTTGGAGGCG GTCTTGGGGG AAAAAAGGAG TCTGGGCAAC TGAGATTTGG GGGACGGGAC 
CGGCCTTTTC GAAAACCTAT TAACTTGCCA GTTGTTAAAA ACGACCTCTA TAGAGAGGGA 
AAACGGGAAA GGCGGGAGCG ATCTCGATCC CGAGAAAGAC ACTGGGACTC GAGGACAAGG 
GATCGAGACC ATGACAGGGG CCGGGAGAAG AGATGGCAAG AAAGAGAGCC GACCAGGGTG 
TGGCCCGACA ATGACTGGGA GAGAGAGAGG GACTTCAGAG ATGACAGGAT CAAGGGGAGG 
GAGAAGAAGG AAAGAGGCAA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011536082.1
CDS394..1317
Translation

Target ORF information:

RefSeq Version XM_011537780.2
Organism Homo sapiens(human)
Definition Homo sapiens small nuclear ribonucleoprotein U11/U12 subunit 35 (SNRNP35), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011537780.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGATAACAC CCTCGTTGCG TGGGAGTAAA ATTTTAAAGG TAAAACAAAC AGGAAACGAG 
CGTCGGCGGC GAATCTGCTG CTACCAATGT AAAGGTCAGG CCGAGGCCGG CGCGGAGAAT 
CTGCTGTCGC CTGCAGCTGC TCGCCTGTCT CCGTCGGAAG GGAGCCCAAG CTTTGCAGAG 
AACATGAACG ATTGGATGCC CATCGCCAAG GAGTATGATC CACTCAAAGC GGGCAGCATT 
GATGGCACCG ATGAAGACCC ACACGACCGC GCGGTCTGGA GGGCAATGCT GGCACGATAT 
GTCCCCAACA AAGGTGTCAT AGGAGATCCC CTCCTCACCC TGTTTGTGGC CAGACTAAAC 
TTGCAGACCA AGGAGGACAA ATTAAAGGAA GTCTTTTCCC GCTATGGTGA CATCCGGCGG 
CTTCGGCTGG TCAGGGACTT GGTCACAGGT TTTTCAAAGG GCTACGCCTT CATCGAATAC 
AAGGAGGAGC GTGCCGTGAT CAAAGCTTAC CGAGATGCTG ATGGCCTGGT TATTGACCAG 
CATGAGATAT TTGTGGACTA CGAGCTGGAA AGGACTCTCA AAGGGTGGAT CCCTCGGCGA 
CTTGGAGGCG GTCTTGGGGG AAAAAAGGAG TCTGGGCAAC TGAGATTTGG GGGACGGGAC 
CGGCCTTTTC GAAAACCTAT TAACTTGCCA GTTGTTAAAA ACGACCTCTA TAGAGAGGGA 
AAACGGGAAA GGCGGGAGCG ATCTCGATCC CGAGAAAGAC ACTGGGACTC GAGGACAAGG 
GATCGAGACC ATGACAGGGG CCGGGAGAAG AGATGGCAAG AAAGAGAGCC GACCAGGGTG 
TGGCCCGACA ATGACTGGGA GAGAGAGAGG GACTTCAGAG ATGACAGGAT CAAGGGGAGG 
GAGAAGAAGG AAAGAGGCAA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
Proceedings of the National Academy of Sciences of the United States of America111(38)13790-4(2014 Sep)
Rietveld CA,Esko T,Davies G,Pers TH,Turley P,Benyamin B,Chabris CF,Emilsson V,Johnson AD,Lee JJ,de Leeuw C,Marioni RE,Medland SE,Miller MB,Rostapshova O,van der Lee SJ,Vinkhuyzen AA,Amin N,Conley D,Derringer J,van Duijn CM,Fehrmann R,Franke L,Glaeser EL,Hansell NK,Hayward C,Iacono WG,Ibrahim-Verbaas C,Jaddoe V,Karjalainen J,Laibson D,Lichtenstein P,Liewald DC,Magnusson PK,Martin NG,McGue M,McMahon G,Pedersen NL,Pinker S,Porteous DJ,Posthuma D,Rivadeneira F,Smith BH,Starr JM,Tiemeier H,Timpson NJ,Trzaskowski M,Uitterlinden AG,Verhulst FC,Ward ME,Wright MJ,Davey Smith G,Deary IJ,Johannesson M,Plomin R,Visscher PM,Benjamin DJ,Cesarini D,Koellinger PD


book

Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
Molecular pharmacology80(2)328-36(2011 Aug)
White GE,McNeill E,Christou I,Channon KM,Greaves DR


book

Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis.
Arthritis and rheumatism61(7)958-65(2009 Jul)
Fertig N,Domsic RT,Rodriguez-Reyna T,Kuwana M,Lucas M,Medsger TA Jr,Feghali-Bostwick CA


book

Minor spliceosome components are predominantly localized in the nucleus.
Proceedings of the National Academy of Sciences of the United States of America105(25)8655-60(2008 Jun)
Pessa HK,Will CL,Meng X,Schneider C,Watkins NJ,Per?l? N,Nymark M,Turunen JJ,L?hrmann R,Frilander MJ


book

The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.
RNA (New York, N.Y.)10(6)929-41(2004 Jun)
Will CL,Schneider C,Hossbach M,Urlaub H,Rauhut R,Elbashir S,Tuschl T,L?hrmann R