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IL1RAPL1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol IL1RAPL1
Entrez Gene ID 11141
Full Name interleukin 1 receptor accessory protein like 1
Synonyms IL-1-RAPL-1,IL-1RAPL-1,IL1R8,IL1RAPL,IL1RAPL-1,MRX10,MRX21,MRX34,OPHN4,TIGIRR-2
General protein information
Preferred Names

interleukin 1 receptor accessory protein like 1

Names

interleukin-1 receptor accessory protein-like 1
X-linked interleukin-1 receptor accessory protein-like 1
interleukin 1 receptor-8
mental retardation, X-linked 10
oligophrenin-4
three immunoglobulin domain-containing IL-1 receptor-related 2

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

X

Xp21.3-p21.2

Summary The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. [provided by RefSeq, Jul 2008].
Disorder MIM:

300206

Disorder Html: Mental retardation, X-linked, 21/34, 300143 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_017029240.1 XP_016884729.1 interleukin-1 receptor accessory protein-like 1 isoform X1
XM_011545445.1 XP_011543747.1 interleukin-1 receptor accessory protein-like 1 isoform X1
XM_017029241.1 XP_016884730.1 interleukin-1 receptor accessory protein-like 1 isoform X2
NM_014271.3 NP_055086.1 interleukin-1 receptor accessory protein-like 1 precursor
XM_005274441.1 XP_005274498.1 interleukin-1 receptor accessory protein-like 1 isoform X1



Bos taurus (cattle) IL1RAPL1 XP_002700320.2
Mus musculus (house mouse) Il1rapl1 NP_001153875.1
Xenopus tropicalis (tropical clawed frog) il1rapl1 XP_002933660.1
Canis lupus familiaris (dog) IL1RAPL1 XP_548919.3
Rattus norvegicus (Norway rat) Il1rapl1 NP_808796.1
Gallus gallus (chicken) IL1RAPL1 XP_425563.3
Homo sapiens (human) IL1RAPL1 NP_055086.1
Pan troglodytes (chimpanzee) IL1RAPL1 NP_001009038.1
Danio rerio (zebrafish) il1rapl1b NP_001136054.1
Macaca mulatta (rhesus monkey) IL1RAPL1 XP_001094959.1


Related articles in PubMed

[Phenotypic analysis of IL1RAPL1 knockout mice].
Yasumura M, Yoshida T, Mishina M
Nihon yakurigaku zasshi. Folia pharmacologica Japonica145(4)187-92(2015 Apr)

Novel IL1RAPL1 mutations associated with intellectual disability impair synaptogenesis.
Ramos-Brossier M, Montani C, Lebrun N, Gritti L, Martin C, Seminatore-Nole C, Toussaint A, Moreno S, Poirier K, Dorseuil O, Chelly J, Hackett A, Gecz J, Bieth E, Faudet A, Heron D, Frank Kooy R, Loeys B, Humeau Y, Sala C, Billuart P
Human molecular genetics24(4)1106-18(2015 Feb)

The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2.
Valnegri P, Montrasio C, Brambilla D, Ko J, Passafaro M, Sala C
Human molecular genetics20(24)4797-809(2011 Dec)

IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ.
Yoshida T, Yasumura M, Uemura T, Lee SJ, Ra M, Taguchi R, Iwakura Y, Mishina M
The Journal of neuroscience : the official journal of the Society for Neuroscience31(38)13485-99(2011 Sep)

No evidence for IL1RAPL1 involvement in selected high-risk autism pedigrees from the AGRE data set.
Allen-Brady K, Cai G, Cannon D, Robison R, McMahon WM, Coon H, Buxbaum JD
Autism research : official journal of the International Society for Autism Research4(4)293-6(2011 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

rs12007907 variant in IL1RAPL gene was negatively associated with asthma and IL-13 production in Latin American children.
Title: Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children.

Our study expands the molecular repertoire of IL1RAPL1 mutations in intellectual disability and points out the need of more accurate clinical descriptions to better define the related phenotype
Title: Clinical and molecular characterization of a boy with intellectual disability, facial dysmorphism, minor digital anomalies and a complex IL1RAPL1 intragenic rearrangement.

It was indicated that a defect in IL1RAPL1 that controls excitatory synapsis formation results in the excitation-inhibition balance affecting various cerebral functions.
Title: [Phenotypic analysis of IL1RAPL1 knockout mice].

Novel IL1RAPL1 mutations associated with intellectual disability impair synaptogenesis.
Title: Novel IL1RAPL1 mutations associated with intellectual disability impair synaptogenesis.

The interaction of the IL1RAPL1 family of proteins with PTPdelta and RhoGAP2 reveals a pathophysiological mechanism of cognitive impairment associated with a novel type of trans-synaptic signaling.
Title: The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2.

The following IL1RAPL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL1RAPL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu19152 NM_014271.3
Latest version!
Homo sapiens interleukin 1 receptor accessory protein like 1 (IL1RAPL1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu19152 XM_017029240.1
Latest version!
Homo sapiens interleukin 1 receptor accessory protein like 1 (IL1RAPL1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu19152 XM_011545445.1
Latest version!
Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu19152 XM_005274441.1
Latest version!
Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu99134 XM_017029241.1
Latest version!
Homo sapiens interleukin 1 receptor accessory protein like 1 (IL1RAPL1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 10-12 $307.30
$439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19152
Clone ID Related Accession (Same CDS sequence) XM_017029240.1 , XM_011545445.1 , NM_014271.3 , XM_005274441.1
Accession Version NM_014271.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2091bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-03
Organism Homo sapiens(Human)
Product interleukin-1 receptor accessory protein-like 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ243874.1, AC112495.2, DN994486.1 and AF284435.1. This sequence is a reference standard in the RefSeqGene project. On Apr 17, 2008 this sequence version replaced NM_014271.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF284435.1, AJ243874.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_055086.1
CDS509..2599
Misc Feature(1)464..466
Misc Feature(2)533..1510
Misc Feature(3)602..913
Misc Feature(4)order(608..610,614..631)
Misc Feature(5)950..1210
Misc Feature(6)1286..1531
Misc Feature(7)1580..1642
Misc Feature(8)1721..2185
Misc Feature(9)2153..2440
Exon (1)1..484
Exon (2)485..590
Exon (3)591..870
Exon (4)871..1057
Exon (5)1058..1211
Exon (6)1212..1286
Exon (7)1287..1419
Exon (8)1420..1565
Exon (9)1566..1709
Exon (10)1710..1880
Exon (11)1881..2679
Translation

Target ORF information:

RefSeq Version NM_014271.3
Organism Homo sapiens(Human)
Definition Homo sapiens interleukin 1 receptor accessory protein like 1 (IL1RAPL1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_014271.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19152
Clone ID Related Accession (Same CDS sequence) XM_017029240.1 , XM_011545445.1 , NM_014271.3 , XM_005274441.1
Accession Version XM_017029240.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2091bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product interleukin-1 receptor accessory protein-like 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016884729.1
CDS965..3055
Misc Feature(1)989..1966
Misc Feature(2)1058..1369
Misc Feature(3)order(1064..1066,1070..1087)
Misc Feature(4)1406..1666
Misc Feature(5)1742..1987
Misc Feature(6)2177..2641
Translation

Target ORF information:

RefSeq Version XM_017029240.1
Organism Homo sapiens(Human)
Definition Homo sapiens interleukin 1 receptor accessory protein like 1 (IL1RAPL1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017029240.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19152
Clone ID Related Accession (Same CDS sequence) XM_017029240.1 , XM_011545445.1 , NM_014271.3 , XM_005274441.1
Accession Version XM_011545445.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2091bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product interleukin-1 receptor accessory protein-like 1 isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011543747.1
Translation

Target ORF information:

RefSeq Version XM_011545445.1
Organism Homo sapiens(Human)
Definition Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545445.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19152
Clone ID Related Accession (Same CDS sequence) XM_017029240.1 , XM_011545445.1 , NM_014271.3 , XM_005274441.1
Accession Version XM_005274441.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2091bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product interleukin-1 receptor accessory protein-like 1 isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005274498.1
Translation

Target ORF information:

RefSeq Version XM_005274441.1
Organism Homo sapiens(Human)
Definition Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005274441.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAAAGCTC CGATTCCACA CTTGATTCTC TTATACGCTA CTTTTACTCA GAGTTTGAAG 
GTTGTGACCA AAAGAGGCTC CGCCGATGGA TGCACTGACT GGTCTATCGA TATCAAGAAA
TATCAAGTTT TGGTGGGAGA GCCTGTTCGA ATCAAATGTG CACTCTTTTA TGGTTATATC
AGAACAAATT ACTCCCTTGC CCAAAGTGCT GGACTCAGTT TGATGTGGTA CAAAAGTTCT
GGTCCTGGAG ACTTTGAAGA GCCAATAGCC TTTGACGGAA GTAGAATGAG CAAAGAAGAA
GACTCCATTT GGTTCCGGCC AACATTGCTA CAGGACAGTG GTCTCTACGC CTGTGTCATC
AGAAACTCCA CTTACTGTAT GAAAGTATCC ATCTCACTGA CAGTGGGTGA AAATGACACT
GGACTCTGCT ATAATTCCAA GATGAAGTAT TTTGAAAAAG CTGAACTTAG CAAAAGCAAG
GAAATTTCAT GCCGTGACAT AGAGGATTTT CTACTGCCAA CCAGAGAACC TGAAATCCTT
TGGTACAAGG AATGCAGGAC AAAAACATGG AGGCCAAGTA TTGTATTCAA AAGAGATACT
CTGCTTATAA GAGAAGTCAG AGAAGATGAC ATTGGAAATT ATACCTGTGA ATTAAAATAT
GGAGGCTTTG TTGTGAGAAG AACTACTGAA TTAACTGTTA CAGCCCCTCT GACTGATAAG
CCACCCAAGC TTTTGTATCC TATGGAAAGT AAACTGACAA TTCAGGAGAC CCAGCTGGGT
GACTCTGCTA ATCTAACCTG CAGAGCTTTC TTTGGGTACA GCGGAGATGT CAGTCCTTTA
ATTTACTGGA TGAAAGGAGA AAAATTTATT GAAGATCTGG ATGAAAATCG AGTTTGGGAA
AGTGACATTA GAATTCTTAA GGAGCATCTT GGGGAACAGG AAGTTTCCAT CTCATTAATT
GTGGACTCTG TGGAAGAAGG TGACTTGGGA AATTACTCCT GTTATGTTGA AAATGGAAAT
GGACGTCGAC ACGCCAGCGT TCTCCTTCAT AAACGAGAGC TAATGTACAC AGTGGAACTT
GCTGGAGGCC TTGGTGCTAT ACTCTTGCTG CTTGTATGTT TGGTGACCAT CTACAAGTGT
TACAAGATAG AAATCATGCT CTTCTACAGG AATCATTTTG GAGCTGAAGA GCTCGATGGA
GACAATAAAG ATTATGATGC ATACTTATCA TACACCAAAG TGGATCCTGA CCAGTGGAAT
CAAGAGACTG GGGAAGAAGA ACGTTTTGCC CTTGAAATCC TACCTGATAT GCTTGAAAAG
CATTATGGAT ATAAGTTGTT TATACCAGAT AGAGATTTAA TCCCAACTGG AACATACATT
GAAGATGTGG CAAGATGTGT AGATCAAAGC AAGCGGCTGA TTATTGTCAT GACCCCAAAT
TACGTAGTTA GAAGGGGCTG GAGCATCTTT GAGCTGGAAA CCAGACTTCG AAATATGCTT
GTGACTGGAG AAATTAAAGT GATTCTAATT GAATGCAGTG AACTGAGAGG AATTATGAAC
TACCAGGAGG TGGAGGCCCT GAAGCACACC ATCAAGCTCC TGACGGTCAT TAAATGGCAT
GGACCAAAAT GCAACAAGTT GAACTCCAAG TTCTGGAAAC GTTTACAGTA TGAAATGCCT
TTTAAGAGGA TAGAACCCAT TACACATGAG CAGGCTTTAG ATGTCAGTGA GCAAGGGCCT
TTTGGGGAGC TGCAGACTGT CTCGGCCATT TCCATGGCCG CGGCCACCTC CACAGCTCTA
GCCACTGCCC ATCCAGATCT CCGTTCTACC TTTCACAACA CGTACCATTC ACAAATGCGT
CAGAAACACT ACTACCGAAG CTATGAGTAC GACGTACCTC CTACCGGCAC CCTGCCTCTT
ACCTCCATAG GCAATCAGCA TACCTACTGT AACATCCCTA TGACACTCAT CAACGGGCAG
CGGCCACAGA CAAAATCGAG CAGGGAGCAG AATCCAGATG AGGCCCACAC AAACAGTGCC
ATCCTGCCGC TGTTGCCAAG GGAGACCAGT ATATCCAGTG TGATATGGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu99134
Clone ID Related Accession (Same CDS sequence) XM_017029241.1
Accession Version XM_017029241.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1713bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product interleukin-1 receptor accessory protein-like 1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGAAAGTAT CCATCTCACT GACAGTGGGT GAAAATGACA CTGGACTCTG CTATAATTCC 
AAGATGAAGT ATTTTGAAAA AGCTGAACTT AGCAAAAGCA AGGAAATTTC ATGCCGTGAC
ATAGAGGATT TTCTACTGCC AACCAGAGAA CCTGAAATCC TTTGGTACAA GGAATGCAGG
ACAAAAACAT GGAGGCCAAG TATTGTATTC AAAAGAGATA CTCTGCTTAT AAGAGAAGTC
AGAGAAGATG ACATTGGAAA TTATACCTGT GAATTAAAAT ATGGAGGCTT TGTTGTGAGA
AGAACTACTG AATTAACTGT TACAGCCCCT CTGACTGATA AGCCACCCAA GCTTTTGTAT
CCTATGGAAA GTAAACTGAC AATTCAGGAG ACCCAGCTGG GTGACTCTGC TAATCTAACC
TGCAGAGCTT TCTTTGGGTA CAGCGGAGAT GTCAGTCCTT TAATTTACTG GATGAAAGGA
GAAAAATTTA TTGAAGATCT GGATGAAAAT CGAGTTTGGG AAAGTGACAT TAGAATTCTT
AAGGAGCATC TTGGGGAACA GGAAGTTTCC ATCTCATTAA TTGTGGACTC TGTGGAAGAA
GGTGACTTGG GAAATTACTC CTGTTATGTT GAAAATGGAA ATGGACGTCG ACACGCCAGC
GTTCTCCTTC ATAAACGAGA GCTAATGTAC ACAGTGGAAC TTGCTGGAGG CCTTGGTGCT
ATACTCTTGC TGCTTGTATG TTTGGTGACC ATCTACAAGT GTTACAAGAT AGAAATCATG
CTCTTCTACA GGAATCATTT TGGAGCTGAA GAGCTCGATG GAGACAATAA AGATTATGAT
GCATACTTAT CATACACCAA AGTGGATCCT GACCAGTGGA ATCAAGAGAC TGGGGAAGAA
GAACGTTTTG CCCTTGAAAT CCTACCTGAT ATGCTTGAAA AGCATTATGG ATATAAGTTG
TTTATACCAG ATAGAGATTT AATCCCAACT GGAACATACA TTGAAGATGT GGCAAGATGT
GTAGATCAAA GCAAGCGGCT GATTATTGTC ATGACCCCAA ATTACGTAGT TAGAAGGGGC
TGGAGCATCT TTGAGCTGGA AACCAGACTT CGAAATATGC TTGTGACTGG AGAAATTAAA
GTGATTCTAA TTGAATGCAG TGAACTGAGA GGAATTATGA ACTACCAGGA GGTGGAGGCC
CTGAAGCACA CCATCAAGCT CCTGACGGTC ATTAAATGGC ATGGACCAAA ATGCAACAAG
TTGAACTCCA AGTTCTGGAA ACGTTTACAG TATGAAATGC CTTTTAAGAG GATAGAACCC
ATTACACATG AGCAGGCTTT AGATGTCAGT GAGCAAGGGC CTTTTGGGGA GCTGCAGACT
GTCTCGGCCA TTTCCATGGC CGCGGCCACC TCCACAGCTC TAGCCACTGC CCATCCAGAT
CTCCGTTCTA CCTTTCACAA CACGTACCAT TCACAAATGC GTCAGAAACA CTACTACCGA
AGCTATGAGT ACGACGTACC TCCTACCGGC ACCCTGCCTC TTACCTCCAT AGGCAATCAG
CATACCTACT GTAACATCCC TATGACACTC ATCAACGGGC AGCGGCCACA GACAAAATCG
AGCAGGGAGC AGAATCCAGA TGAGGCCCAC ACAAACAGTG CCATCCTGCC GCTGTTGCCA
AGGGAGACCA GTATATCCAG TGTGATATGG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016884730.1
CDS4644..6356
Misc Feature(1)4707..4967
Misc Feature(2)<4791..4964
Misc Feature(3)5028..5315
Misc Feature(4)5043..5288
Misc Feature(5)5478..5942
Translation

Target ORF information:

RefSeq Version XM_017029241.1
Organism Homo sapiens(Human)
Definition Homo sapiens interleukin 1 receptor accessory protein like 1 (IL1RAPL1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017029241.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGAAAGTAT CCATCTCACT GACAGTGGGT GAAAATGACA CTGGACTCTG CTATAATTCC 
AAGATGAAGT ATTTTGAAAA AGCTGAACTT AGCAAAAGCA AGGAAATTTC ATGCCGTGAC
ATAGAGGATT TTCTACTGCC AACCAGAGAA CCTGAAATCC TTTGGTACAA GGAATGCAGG
ACAAAAACAT GGAGGCCAAG TATTGTATTC AAAAGAGATA CTCTGCTTAT AAGAGAAGTC
AGAGAAGATG ACATTGGAAA TTATACCTGT GAATTAAAAT ATGGAGGCTT TGTTGTGAGA
AGAACTACTG AATTAACTGT TACAGCCCCT CTGACTGATA AGCCACCCAA GCTTTTGTAT
CCTATGGAAA GTAAACTGAC AATTCAGGAG ACCCAGCTGG GTGACTCTGC TAATCTAACC
TGCAGAGCTT TCTTTGGGTA CAGCGGAGAT GTCAGTCCTT TAATTTACTG GATGAAAGGA
GAAAAATTTA TTGAAGATCT GGATGAAAAT CGAGTTTGGG AAAGTGACAT TAGAATTCTT
AAGGAGCATC TTGGGGAACA GGAAGTTTCC ATCTCATTAA TTGTGGACTC TGTGGAAGAA
GGTGACTTGG GAAATTACTC CTGTTATGTT GAAAATGGAA ATGGACGTCG ACACGCCAGC
GTTCTCCTTC ATAAACGAGA GCTAATGTAC ACAGTGGAAC TTGCTGGAGG CCTTGGTGCT
ATACTCTTGC TGCTTGTATG TTTGGTGACC ATCTACAAGT GTTACAAGAT AGAAATCATG
CTCTTCTACA GGAATCATTT TGGAGCTGAA GAGCTCGATG GAGACAATAA AGATTATGAT
GCATACTTAT CATACACCAA AGTGGATCCT GACCAGTGGA ATCAAGAGAC TGGGGAAGAA
GAACGTTTTG CCCTTGAAAT CCTACCTGAT ATGCTTGAAA AGCATTATGG ATATAAGTTG
TTTATACCAG ATAGAGATTT AATCCCAACT GGAACATACA TTGAAGATGT GGCAAGATGT
GTAGATCAAA GCAAGCGGCT GATTATTGTC ATGACCCCAA ATTACGTAGT TAGAAGGGGC
TGGAGCATCT TTGAGCTGGA AACCAGACTT CGAAATATGC TTGTGACTGG AGAAATTAAA
GTGATTCTAA TTGAATGCAG TGAACTGAGA GGAATTATGA ACTACCAGGA GGTGGAGGCC
CTGAAGCACA CCATCAAGCT CCTGACGGTC ATTAAATGGC ATGGACCAAA ATGCAACAAG
TTGAACTCCA AGTTCTGGAA ACGTTTACAG TATGAAATGC CTTTTAAGAG GATAGAACCC
ATTACACATG AGCAGGCTTT AGATGTCAGT GAGCAAGGGC CTTTTGGGGA GCTGCAGACT
GTCTCGGCCA TTTCCATGGC CGCGGCCACC TCCACAGCTC TAGCCACTGC CCATCCAGAT
CTCCGTTCTA CCTTTCACAA CACGTACCAT TCACAAATGC GTCAGAAACA CTACTACCGA
AGCTATGAGT ACGACGTACC TCCTACCGGC ACCCTGCCTC TTACCTCCAT AGGCAATCAG
CATACCTACT GTAACATCCC TATGACACTC ATCAACGGGC AGCGGCCACA GACAAAATCG
AGCAGGGAGC AGAATCCAGA TGAGGCCCAC ACAAACAGTG CCATCCTGCC GCTGTTGCCA
AGGGAGACCA GTATATCCAG TGTGATATGG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

[Phenotypic analysis of IL1RAPL1 knockout mice].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica145(4)187-92(2015 Apr)
Yasumura M,Yoshida T,Mishina M


book

Novel IL1RAPL1 mutations associated with intellectual disability impair synaptogenesis.
Human molecular genetics24(4)1106-18(2015 Feb)
Ramos-Brossier M,Montani C,Lebrun N,Gritti L,Martin C,Seminatore-Nole C,Toussaint A,Moreno S,Poirier K,Dorseuil O,Chelly J,Hackett A,Gecz J,Bieth E,Faudet A,Heron D,Frank Kooy R,Loeys B,Humeau Y,Sala C,Billuart P


book

The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2.
Human molecular genetics20(24)4797-809(2011 Dec)
Valnegri P,Montrasio C,Brambilla D,Ko J,Passafaro M,Sala C


book

IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(38)13485-99(2011 Sep)
Yoshida T,Yasumura M,Uemura T,Lee SJ,Ra M,Taguchi R,Iwakura Y,Mishina M


book

No evidence for IL1RAPL1 involvement in selected high-risk autism pedigrees from the AGRE data set.
Autism research : official journal of the International Society for Autism Research4(4)293-6(2011 Aug)
Allen-Brady K,Cai G,Cannon D,Robison R,McMahon WM,Coon H,Buxbaum JD


 
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