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CMTM1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol CMTM1
Entrez Gene ID 113540
Full Name CKLF like MARVEL transmembrane domain containing 1
Synonyms CKLFH,CKLFH1,CKLFSF1
General protein information
Preferred Names

CKLF like MARVEL transmembrane domain containing 1

Names

CKLF-like MARVEL transmembrane domain-containing protein 1
chemokine-like factor super family 1
chemokine-like factor superfamily 1
chemokine-like factor superfamily member 1
chemokine-like factor-like protein CKLFH1

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

16

16q21

Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).[provided by RefSeq, Feb 2011].
Disorder MIM:

607884


mRNA and Protein(s)

mRNA Protein Name
NM_181269.2 NP_851786.1 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 1
NM_181272.2 NP_851789.1 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 4
NM_052999.3 NP_443725.3 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 13
NM_181271.2 NP_851788.1 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 3
NM_181268.2 NP_851785.2 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 14
NM_181270.2 NP_851787.1 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 2
NM_181283.2 NP_851800.1 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 5
NM_181296.2 NP_851813.1 CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 12



Homo sapiens (human) CMTM1 NP_443725.3
Pan troglodytes (chimpanzee) LOC100610567 XP_003315186.1
Canis lupus familiaris (dog) CMTM1 NP_001239274.1
Bos taurus (cattle) LOC525286 XP_005218893.1
Macaca mulatta (rhesus monkey) LOC715757 XP_001083621.2


Related articles in PubMed

Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets.
Delic S, Thuy A, Schulze M, Proescholdt MA, Dietrich P, Bosserhoff AK, Riemenschneider MJ
Genes, chromosomes & cancer54(7)433-43(2015 Jul)

CMTM1_v17 is a novel potential therapeutic target in breast cancer.
Wang J, Zhang G, Zhang Y, Luo Y, Song Q, Qiu X, Mo X, Wang L
Oncology reports32(5)1829-36(2014 Nov)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

A functional promoter region of the CKLFSF2 gene is located in the last intron/exon region of the upstream CKLFSF1 gene.
Xu M, Yang S, Gao Y, Shi S, Ma D
The international journal of biochemistry & cell biology37(6)1296-307(2005 Jun)

Molecular cloning and characterization of chemokine-like factor super family member 1 (CKLFSF1), a novel human gene with at least 23 alternative splicing isoforms in testis tissue.
Wang L, Wu C, Zheng Y, Qiu X, Wang L, Fan H, Han W, Lv B, Wang Y, Zhu X, Xu M, Ding P, Cheng S, Zhang Y, Song Q, Ma D
The international journal of biochemistry & cell biology36(8)1492-501(2004 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High CMTM1_v17 expression was associated with chemotherapy resistance in lung cancer.
Title: CMTM1_v17 is associated with chemotherapy resistance and poor prognosis in non-small cell lung cancer.

CMTM1 and 3 are priority targets in glioblastomas. First insights into signalling of these two genes that might be conveyed by growth factor receptor, Src family kinase and WNT activation was presented.
Title: Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets.

Study shows that CMTM1_v17 is highly expressed in human testis and many human tumor tissues and cell lines and seems to enhance cell proliferation and resistance to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis in MDA-MB-231 breast cancer cells.
Title: CMTM1_v17 is a novel potential therapeutic target in breast cancer.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

novel evidence that the final intron/exon region of the CKLFSF1 gene contains a novel eukaryotic promoter capable of directing expression of the downstream gene, CKLFSF2
Title: A functional promoter region of the CKLFSF2 gene is located in the last intron/exon region of the upstream CKLFSF1 gene.

The following CMTM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CMTM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu07548 NM_181270.2
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu07549 NM_181269.2
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu29931 NM_181271.2
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu30589 NM_052999.3
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 17, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu30710 NM_181296.2
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 16, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu30744 NM_181272.2
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu30867 NM_181283.2
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu31059 NM_181268.2
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 18, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $188.30
$269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu07548
Clone ID Related Accession (Same CDS sequence) NM_181270.2
Accession Version NM_181270.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 345bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-08-25
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1 and AY174119.1. On Jun 8, 2007 this sequence version replaced NM_181270.1. Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 17, one of which results in a translational frameshift in the last coding exon. The encoded isoform (2) is shorter and contains a distinct C-terminus, compared to the protein (isoform 13) encoded by variant 17. ##Evidence-Data-START## Transcript exon combination :: AY174119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GAGTCTTATC TTAGGAGCAT TAGCTTGTTT CATCATCACC
CAAGCCAATG AGTCATTTAT AACAATCACA AGTCTGGAAA TCTGCATTGT CGTTTTTTTT
ATTCTAATAT ATGTGCTAAC CCTTCACCAC TTGCTGACCT ATTTACATTG GCCCTTACTT
GATCTTACCA ACAGTATCAT TACAGCTGTG TTCCTTTCAG TAGTTGCCAT CTTGGCCATG
CAAGAAAAGA AAAGAAGGCA TTTACTCTAT GTCGGGGGGC GGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851787.1
CDS124..468
Misc Feature(1)112..114
Misc Feature(2)<127..417
Misc Feature(3)187..249
Misc Feature(4)259..321
Misc Feature(5)358..420
Exon (1)1..204
Exon (2)205..363
Exon (3)364..462
Exon (4)463..751
Translation

Target ORF information:

RefSeq Version NM_181270.2
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181270.2

ORF Insert Sequence:

1
61
121
181
241
301
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GAGTCTTATC TTAGGAGCAT TAGCTTGTTT CATCATCACC
CAAGCCAATG AGTCATTTAT AACAATCACA AGTCTGGAAA TCTGCATTGT CGTTTTTTTT
ATTCTAATAT ATGTGCTAAC CCTTCACCAC TTGCTGACCT ATTTACATTG GCCCTTACTT
GATCTTACCA ACAGTATCAT TACAGCTGTG TTCCTTTCAG TAGTTGCCAT CTTGGCCATG
CAAGAAAAGA AAAGAAGGCA TTTACTCTAT GTCGGGGGGC GGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07549
Clone ID Related Accession (Same CDS sequence) NM_181269.2
Accession Version NM_181269.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 510bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-08-25
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1 and AY174118.1. On Jun 8, 2007 this sequence version replaced NM_181269.1. Transcript Variant: This variant (1) lacks an alternate in-frame segment of the first coding exon, compared to variant 17. The encoded isoform (1) is shorter than the protein (isoform 13) encoded by variant 17. ##Evidence-Data-START## Transcript exon combination :: AY174118.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GAGTCTTATC TTAGGAGCAT TAGCTTGTTT CATCATCACC
CAAGCCAATG AGTCATTTAT AACAATCACA AGTCTGGAAA TCTGCATTGT CGTTTTTTTT
ATTCTAATAT ATGTGCTAAC CCTTCACCAC TTGCTGACCT ATTTACATTG GCCCTTACTT
GATCTTACCA ACAGTATCAT TACAGCTGTG TTCCTTTCAG TAGTTGCCAT CTTGGCCATG
CAAGAAAAGA AAAGAAGGCA TTTACTCTAT GTCGGGGGGT CCCTGTGTCT CACAGCGGTA
ATCGTGTGTT GCATCGATGC GTTTGTGGTC ACCACGAAGA TGAGGACCAA CTTGAAAAGA
TTCCTGGGAG TCGAAGTTGA AAGGAAGCTT TCCCCCGCCA AGGACGCCTA CCCCGAAACC
GGCCCCGACG CCCCGCAGAG GCCCGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851786.1
CDS124..633
Misc Feature(1)112..114
Misc Feature(2)<127..417
Misc Feature(3)187..249
Misc Feature(4)259..321
Misc Feature(5)358..420
Misc Feature(6)451..513
Exon (1)1..204
Exon (2)205..363
Exon (3)364..462
Exon (4)463..767
Translation

Target ORF information:

RefSeq Version NM_181269.2
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181269.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GAGTCTTATC TTAGGAGCAT TAGCTTGTTT CATCATCACC
CAAGCCAATG AGTCATTTAT AACAATCACA AGTCTGGAAA TCTGCATTGT CGTTTTTTTT
ATTCTAATAT ATGTGCTAAC CCTTCACCAC TTGCTGACCT ATTTACATTG GCCCTTACTT
GATCTTACCA ACAGTATCAT TACAGCTGTG TTCCTTTCAG TAGTTGCCAT CTTGGCCATG
CAAGAAAAGA AAAGAAGGCA TTTACTCTAT GTCGGGGGGT CCCTGTGTCT CACAGCGGTA
ATCGTGTGTT GCATCGATGC GTTTGTGGTC ACCACGAAGA TGAGGACCAA CTTGAAAAGA
TTCCTGGGAG TCGAAGTTGA AAGGAAGCTT TCCCCCGCCA AGGACGCCTA CCCCGAAACC
GGCCCCGACG CCCCGCAGAG GCCCGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29931
Clone ID Related Accession (Same CDS sequence) NM_181271.2
Accession Version NM_181271.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 369bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-08-25
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1 and AY174120.1. On Jun 8, 2007 this sequence version replaced NM_181271.1. Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 17. The encoded isoform (3) is shorter than the protein (isoform 13) encoded by variant 17. ##Evidence-Data-START## Transcript exon combination :: AY174120.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGCAAGTAGC GGCAGCGTAG ATCTTACCAA CAGTATCATT
ACAGCTGTGT TCCTTTCAGT AGTTGCCATC TTGGCCATGC AAGAAAAGAA AAGAAGGCAT
TTACTCTATG TCGGGGGGTC CCTGTGTCTC ACAGCGGTAA TCGTGTGTTG CATCGATGCG
TTTGTGGTCA CCACGAAGAT GAGGACCAAC TTGAAAAGAT TCCTGGGAGT CGAAGTTGAA
AGGAAGCTTT CCCCCGCCAA GGACGCCTAC CCCGAAACCG GCCCCGACGC CCCGCAGAGG
CCCGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851788.1
CDS124..492
Misc Feature(1)112..114
Exon (1)1..222
Exon (2)223..321
Exon (3)322..626
Translation

Target ORF information:

RefSeq Version NM_181271.2
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181271.2

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGCAAGTAGC GGCAGCGTAG ATCTTACCAA CAGTATCATT
ACAGCTGTGT TCCTTTCAGT AGTTGCCATC TTGGCCATGC AAGAAAAGAA AAGAAGGCAT
TTACTCTATG TCGGGGGGTC CCTGTGTCTC ACAGCGGTAA TCGTGTGTTG CATCGATGCG
TTTGTGGTCA CCACGAAGAT GAGGACCAAC TTGAAAAGAT TCCTGGGAGT CGAAGTTGAA
AGGAAGCTTT CCCCCGCCAA GGACGCCTAC CCCGAAACCG GCCCCGACGC CCCGCAGAGG
CCCGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu30589
Clone ID Related Accession (Same CDS sequence) NM_052999.3
Accession Version NM_052999.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 861bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-08-25
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 13
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1, BC057852.1 and AY174119.1. On Jun 8, 2007 this sequence version replaced NM_052999.2. Transcript Variant: This variant (17) encodes the longest isoform (13). ##Evidence-Data-START## Transcript exon combination :: BC057852.1, AF278577.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGCAAGTAGC GGCAGCGTAG TGAGTTCTGT ACCCAAGGCA
CAGCGCAACA TCTCAGCGAA GACCGCACCC CGGAAGCACC CCGCAGTCTC AATTCGCAGT
GCGCAGTCCG CAGCCGCCGC ACGTCCCCAA GGCAGTGAGG GCACCGCACC CTCAAGGAAA
GCCACCACAC GCCCACCCCC AAAGCCCACA CTCCCACCCC CCACGCCCTC TGCACACACT
GAATCCAAAC TCTTAAATGA GATGGCGATC AAAGAGCGCG TGGAGGGCCG AGCCAAAGTC
CCGTACAAAT TCAGGGACAG CCTCAAACGT TTCTCCTTCT CGCCCACTGG AATGTTGAAG
ATCCTGAGAC TGAGTCTTAT CTTAGGAGCA TTAGCTTGTT TCATCATCAC CCAAGCCAAT
GAGTCATTTA TAACAATCAC AAGTCTGGAA ATCTGCATTG TCGTTTTTTT TATTCTAATA
TATGTGCTAA CCCTTCACCA CTTGCTGACC TATTTACATT GGCCCTTACT TGATCTTACC
AACAGTATCA TTACAGCTGT GTTCCTTTCA GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG
AAAAGAAGGC ATTTACTCTA TGTCGGGGGG TCCCTGTGTC TCACAGCGGT AATCGTGTGT
TGCATCGATG CGTTTGTGGT CACCACGAAG ATGAGGACCA ACTTGAAAAG ATTCCTGGGA
GTCGAAGTTG AAAGGAAGCT TTCCCCCGCC AAGGACGCCT ACCCCGAAAC CGGCCCCGAC
GCCCCGCAGA GGCCCGCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_443725.3
CDS68..928
Misc Feature(1)16
Misc Feature(2)56..58
Misc Feature(3)458..>715
Misc Feature(4)479..481
Misc Feature(5)356
Exon (1)1..499
Exon (2)500..658
Exon (3)659..757
Exon (4)758..1062
Translation

Target ORF information:

RefSeq Version NM_052999.3
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 17, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_052999.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGCAAGTAGC GGCAGCGTAG TGAGTTCTGT ACCCAAGGCA
CAGCGCAACA TCTCAGCGAA GACCGCACCC CGGAAGCACC CCGCAGTCTC AATTCGCAGT
GCGCAGTCCG CAGCCGCCGC ACGTCCCCAA GGCAGTGAGG GCACCGCACC CTCAAGGAAA
GCCACCACAC GCCCACCCCC AAAGCCCACA CTCCCACCCC CCACGCCCTC TGCACACACT
GAATCCAAAC TCTTAAATGA GATGGCGATC AAAGAGCGCG TGGAGGGCCG AGCCAAAGTC
CCGTACAAAT TCAGGGACAG CCTCAAACGT TTCTCCTTCT CGCCCACTGG AATGTTGAAG
ATCCTGAGAC TGAGTCTTAT CTTAGGAGCA TTAGCTTGTT TCATCATCAC CCAAGCCAAT
GAGTCATTTA TAACAATCAC AAGTCTGGAA ATCTGCATTG TCGTTTTTTT TATTCTAATA
TATGTGCTAA CCCTTCACCA CTTGCTGACC TATTTACATT GGCCCTTACT TGATCTTACC
AACAGTATCA TTACAGCTGT GTTCCTTTCA GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG
AAAAGAAGGC ATTTACTCTA TGTCGGGGGG TCCCTGTGTC TCACAGCGGT AATCGTGTGT
TGCATCGATG CGTTTGTGGT CACCACGAAG ATGAGGACCA ACTTGAAAAG ATTCCTGGGA
GTCGAAGTTG AAAGGAAGCT TTCCCCCGCC AAGGACGCCT ACCCCGAAAC CGGCCCCGAC
GCCCCGCAGA GGCCCGCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu30710
Clone ID Related Accession (Same CDS sequence) NM_181296.2
Accession Version NM_181296.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 87bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-08-25
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 12
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1 and AY174133.1. On Jun 8, 2007 this sequence version replaced NM_181296.1. Transcript Variant: This variant (16) has multiple differences in the coding region, compared to variant 17, one of which results in a translational frameshift in the last coding exon. The encoded isoform (12) is shorter and contains a distinct C-terminus, compared to the protein (isoform 13) encoded by variant 17. ##Evidence-Data-START## Transcript exon combination :: AY174133.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GCGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851813.1
CDS124..210
Misc Feature(1)112..114
Exon (1)1..204
Exon (2)205..493
Translation

Target ORF information:

RefSeq Version NM_181296.2
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 16, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181296.2

ORF Insert Sequence:

1
61
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GCGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu30744
Clone ID Related Accession (Same CDS sequence) NM_181272.2
Accession Version NM_181272.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 351bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-08-25
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1 and AY174121.1. On Jun 8, 2007 this sequence version replaced NM_181272.1. Transcript Variant: This variant (4) has multiple differences in the 5' coding region, compared to variant 17. The encoded isoform (4) is shorter than the protein (isoform 13) encoded by variant 17. ##Evidence-Data-START## Transcript exon combination :: AY174121.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGATCTTACC AACAGTATCA TTACAGCTGT GTTCCTTTCA
GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG AAAAGAAGGC ATTTACTCTA TGTCGGGGGG
TCCCTGTGTC TCACAGCGGT AATCGTGTGT TGCATCGATG CGTTTGTGGT CACCACGAAG
ATGAGGACCA ACTTGAAAAG ATTCCTGGGA GTCGAAGTTG AAAGGAAGCT TTCCCCCGCC
AAGGACGCCT ACCCCGAAAC CGGCCCCGAC GCCCCGCAGA GGCCCGCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851789.1
CDS124..474
Misc Feature(1)112..114
Exon (1)1..204
Exon (2)205..303
Exon (3)304..608
Translation

Target ORF information:

RefSeq Version NM_181272.2
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181272.2

ORF Insert Sequence:

1
61
121
181
241
301
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGATCTTACC AACAGTATCA TTACAGCTGT GTTCCTTTCA
GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG AAAAGAAGGC ATTTACTCTA TGTCGGGGGG
TCCCTGTGTC TCACAGCGGT AATCGTGTGT TGCATCGATG CGTTTGTGGT CACCACGAAG
ATGAGGACCA ACTTGAAAAG ATTCCTGGGA GTCGAAGTTG AAAGGAAGCT TTCCCCCGCC
AAGGACGCCT ACCCCGAAAC CGGCCCCGAC GCCCCGCAGA GGCCCGCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu30867
Clone ID Related Accession (Same CDS sequence) NM_181283.2
Accession Version NM_181283.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 186bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-08-25
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 5
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1 and AY174122.1. On Jun 8, 2007 this sequence version replaced NM_181283.1. Transcript Variant: This variant (5) has multiple differences in the coding region, compared to variant 17, one of which results in a translational frameshift in the last coding exon. The encoded isoform (5) is shorter and contains a distinct C-terminus, compared to the protein (isoform 13) encoded by variant 17. ##Evidence-Data-START## Transcript exon combination :: AY174122.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGATCTTACC AACAGTATCA TTACAGCTGT GTTCCTTTCA
GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG AAAAGAAGGC ATTTACTCTA TGTCGGGGGG
CGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851800.1
CDS124..309
Misc Feature(1)112..114
Exon (1)1..204
Exon (2)205..303
Exon (3)304..592
Translation

Target ORF information:

RefSeq Version NM_181283.2
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181283.2

ORF Insert Sequence:

1
61
121
181
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGATCTTACC AACAGTATCA TTACAGCTGT GTTCCTTTCA
GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG AAAAGAAGGC ATTTACTCTA TGTCGGGGGG
CGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu31059
Clone ID Related Accession (Same CDS sequence) NM_181268.2
Accession Version NM_181268.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 696bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-30
Organism Homo sapiens(Human)
Product CKLF-like MARVEL transmembrane domain-containing protein 1 isoform 14
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN992496.1, BC057852.1 and AY174119.1. On Jun 8, 2007 this sequence version replaced NM_181268.1. Transcript Variant: This variant (18) lacks an exon segment, compared to variant 17, which results in a translational frameshift in the last coding exon. The encoded isoform (14) is shorter and contains a distinct C-terminus, compared to the protein (isoform 13) encoded by variant 17. ##Evidence-Data-START## Transcript exon combination :: AF278576.1, AI825627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGCAAGTAGC GGCAGCGTAG TGAGTTCTGT ACCCAAGGCA
CAGCGCAACA TCTCAGCGAA GACCGCACCC CGGAAGCACC CCGCAGTCTC AATTCGCAGT
GCGCAGTCCG CAGCCGCCGC ACGTCCCCAA GGCAGTGAGG GCACCGCACC CTCAAGGAAA
GCCACCACAC GCCCACCCCC AAAGCCCACA CTCCCACCCC CCACGCCCTC TGCACACACT
GAATCCAAAC TCTTAAATGA GATGGCGATC AAAGAGCGCG TGGAGGGCCG AGCCAAAGTC
CCGTACAAAT TCAGGGACAG CCTCAAACGT TTCTCCTTCT CGCCCACTGG AATGTTGAAG
ATCCTGAGAC TGAGTCTTAT CTTAGGAGCA TTAGCTTGTT TCATCATCAC CCAAGCCAAT
GAGTCATTTA TAACAATCAC AAGTCTGGAA ATCTGCATTG TCGTTTTTTT TATTCTAATA
TATGTGCTAA CCCTTCACCA CTTGCTGACC TATTTACATT GGCCCTTACT TGATCTTACC
AACAGTATCA TTACAGCTGT GTTCCTTTCA GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG
AAAAGAAGGC ATTTACTCTA TGTCGGGGGG CGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_851785.2
CDS68..763
Misc Feature(1)16
Misc Feature(2)56..58
Misc Feature(3)458..>715
Misc Feature(4)479..481
Misc Feature(5)356
Exon (1)1..499
Exon (2)500..658
Exon (3)659..757
Exon (4)758..1046
Translation

Target ORF information:

RefSeq Version NM_181268.2
Organism Homo sapiens(Human)
Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 18, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181268.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGATCCTG AACACGCCAA ACCTGAGTCA TCCGAGGCAC CTTCAGGGAA CTTGAAACAA 
CCGGAGACTG CCGCAGCCCT GGCAAGTAGC GGCAGCGTAG TGAGTTCTGT ACCCAAGGCA
CAGCGCAACA TCTCAGCGAA GACCGCACCC CGGAAGCACC CCGCAGTCTC AATTCGCAGT
GCGCAGTCCG CAGCCGCCGC ACGTCCCCAA GGCAGTGAGG GCACCGCACC CTCAAGGAAA
GCCACCACAC GCCCACCCCC AAAGCCCACA CTCCCACCCC CCACGCCCTC TGCACACACT
GAATCCAAAC TCTTAAATGA GATGGCGATC AAAGAGCGCG TGGAGGGCCG AGCCAAAGTC
CCGTACAAAT TCAGGGACAG CCTCAAACGT TTCTCCTTCT CGCCCACTGG AATGTTGAAG
ATCCTGAGAC TGAGTCTTAT CTTAGGAGCA TTAGCTTGTT TCATCATCAC CCAAGCCAAT
GAGTCATTTA TAACAATCAC AAGTCTGGAA ATCTGCATTG TCGTTTTTTT TATTCTAATA
TATGTGCTAA CCCTTCACCA CTTGCTGACC TATTTACATT GGCCCTTACT TGATCTTACC
AACAGTATCA TTACAGCTGT GTTCCTTTCA GTAGTTGCCA TCTTGGCCAT GCAAGAAAAG
AAAAGAAGGC ATTTACTCTA TGTCGGGGGG CGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets.
Genes, chromosomes & cancer54(7)433-43(2015 Jul)
Delic S,Thuy A,Schulze M,Proescholdt MA,Dietrich P,Bosserhoff AK,Riemenschneider MJ


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CMTM1_v17 is a novel potential therapeutic target in breast cancer.
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Wang J,Zhang G,Zhang Y,Luo Y,Song Q,Qiu X,Mo X,Wang L


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New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M


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A functional promoter region of the CKLFSF2 gene is located in the last intron/exon region of the upstream CKLFSF1 gene.
The international journal of biochemistry & cell biology37(6)1296-307(2005 Jun)
Xu M,Yang S,Gao Y,Shi S,Ma D


book

Molecular cloning and characterization of chemokine-like factor super family member 1 (CKLFSF1), a novel human gene with at least 23 alternative splicing isoforms in testis tissue.
The international journal of biochemistry & cell biology36(8)1492-501(2004 Aug)
Wang L,Wu C,Zheng Y,Qiu X,Wang L,Fan H,Han W,Lv B,Wang Y,Zhu X,Xu M,Ding P,Cheng S,Zhang Y,Song Q,Ma D


 
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