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TADA1 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol TADA1
Entrez Gene ID 117143
Full Name transcriptional adaptor 1
Synonyms ADA1,HFI1,STAF42,TADA1L,hADA1
General protein information
Preferred Names

transcriptional adaptor 1

Names

transcriptional adapter 1
SPT3-associated factor 42 (STAF42)
transcriptional adapter 1-like protein
transcriptional adaptor 1 (HFI1 homolog, yeast)
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

1

1q24.1
Summary TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009].
Disorder MIM:

612763


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_053053.4 NP_444281.1 transcriptional adapter 1
NM_053053.3 NP_444281.1 transcriptional adapter 1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) TADA1 XP_513967.1
Bos taurus (cattle) TADA1 NP_001094576.1
Rattus norvegicus (Norway rat) Tada1 NP_001033069.2
Danio rerio (zebrafish) tada1 NP_991169.1
TADA1 XP_001087291.1
Mus musculus (house mouse) Tada1 NP_084521.1
Gallus gallus (chicken) TADA1L NP_001183965.1
Xenopus tropicalis (tropical clawed frog) tada1 NP_001005070.1
Homo sapiens (human) TADA1 NP_444281.1
Drosophila melanogaster (fruit fly) Ada1-2 NP_723703.1
Drosophila melanogaster (fruit fly) Ada1-1 NP_723707.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP004085 XP_309635.4
Canis lupus familiaris (dog) TADA1 XP_537213.2

Gene Ontology


Bibliography

Related articles in PubMed

Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA.
Gloria-Bottini F, Nicotra M, Amante A, Ambrosi S, Cozzoli E, Saccucci P, Bottini E, Magrini A
American journal of human biology : the official journal of the Human Biology Council24(2)177-82(2012 Mar-Apr)

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A
European journal of human genetics : EJHG17(12)1650-7(2009 Dec)

Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.
Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW
Human molecular genetics18(4)679-87(2009 Feb)

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG
Molecular and cellular biology21(20)6782-95(2001 Oct)

A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.
Martinez E, Kundu TK, Fu J, Roeder RG
The Journal of biological chemistry273(37)23781-5(1998 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Differences between mother and fetus in ADA(1) phenotype may influence the ratio BW/PW in healthy women and reproductive success in RSA women.
Title: Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA.

Observational study of gene-disease association. (HuGE Navigator)
Title: Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.

The following TADA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TADA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu13657 NM_053053.4
Latest version!		 Homo sapiens transcriptional adaptor 1 (TADA1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $139.50-$195.30
$279.00
View Old Accession Versions >>
OHu13657 NM_053053.3 Homo sapiens transcriptional adaptor 1 (TADA1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $139.50-$195.30
$279.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu13657
Clone ID Related Accession (Same CDS sequence) NM_053053.4 , NM_053053.3
Accession Version NM_053053.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1008bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-26
Organism Homo sapiens(human)
Product transcriptional adapter 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN399642.1 and BC015401.2. On Nov 22, 2018 this sequence version replaced NM_053053.3. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1045213.1, SRR3476690.1132206.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367874.5/ ENSP00000356848.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_444281.1
CDS32..1039
Translation

Target ORF information:

RefSeq Version NM_053053.4
Organism Homo sapiens(human)
Definition Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_053053.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu13657
Clone ID Related Accession (Same CDS sequence) NM_053053.4 , NM_053053.3
Accession Version NM_053053.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1008bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product transcriptional adapter 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN399642.1 and BC015401.2. On Nov 1, 2008 this sequence version replaced NM_053053.2. ##Evidence-Data-START## Transcript exon combination :: BC015401.2, SRR1660807.135199.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_444281.1
CDS185..1192
Translation

Target ORF information:

RefSeq Version NM_053053.3
Organism Homo sapiens(human)
Definition Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_053053.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA.
American journal of human biology : the official journal of the Human Biology Council24(2)177-82(2012 Mar-Apr)
Gloria-Bottini F,Nicotra M,Amante A,Ambrosi S,Cozzoli E,Saccucci P,Bottini E,Magrini A


book

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
European journal of human genetics : EJHG17(12)1650-7(2009 Dec)
Ehret GB,O'Connor AA,Weder A,Cooper RS,Chakravarti A


book

Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.
Human molecular genetics18(4)679-87(2009 Feb)
Cheung CL,Chan BY,Chan V,Ikegawa S,Kou I,Ngai H,Smith D,Luk KD,Huang QY,Mori S,Sham PC,Kung AW


book

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Molecular and cellular biology21(20)6782-95(2001 Oct)
Martinez E,Palhan VB,Tjernberg A,Lymar ES,Gamper AM,Kundu TK,Chait BT,Roeder RG


book

A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.
The Journal of biological chemistry273(37)23781-5(1998 Sep)
Martinez E,Kundu TK,Fu J,Roeder RG