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TPPP2 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol TPPP2
Entrez Gene ID 122664
Full Name tubulin polymerization promoting protein family member 2
Synonyms C14orf8,CT152,P18,p25beta
General protein information
Preferred Names

tubulin polymerization promoting protein family member 2

Names

tubulin polymerization-promoting protein family member 2
TPPP/p18
protein p25-beta
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

14

14q11.2
Disorder MIM:

616956


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_011536416.1 XP_011534718.1 tubulin polymerization-promoting protein family member 2 isoform X2
XM_011536417.2 XP_011534719.1 tubulin polymerization-promoting protein family member 2 isoform X3
XM_011536418.1 XP_011534720.1 tubulin polymerization-promoting protein family member 2 isoform X3
XM_011536420.2 XP_011534722.1 tubulin polymerization-promoting protein family member 2 isoform X3
NM_173846.4 NP_776245.2 tubulin polymerization-promoting protein family member 2
XM_017020966.1 XP_016876455.1 tubulin polymerization-promoting protein family member 2 isoform X1
NM_173846.5 NP_776245.2 tubulin polymerization-promoting protein family member 2
XM_005267324.3 XP_005267381.1 tubulin polymerization-promoting protein family member 2 isoform X1
XM_005267324.4 XP_005267381.1 tubulin polymerization-promoting protein family member 2 isoform X1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) TPPP2 XP_528697.2
Rattus norvegicus (Norway rat) Tppp2 NP_001102570.1
Caenorhabditis elegans (roundworm) C32E8.3 NP_491219.1
Homo sapiens (human) TPPP2 NP_776245.2
Canis lupus familiaris (dog) TPPP2 XP_532620.2
Mus musculus (house mouse) Tppp2 NP_001122106.1
Bos taurus (cattle) TPPP2 NP_001029456.1
Gallus gallus (chicken) TPPP2 XP_424853.1
TPPP2 XP_001093843.1

Gene Ontology


Bibliography

Related articles in PubMed

Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions.
Vincze O, T?k?si N, Ol?h J, Hlavanda E, Zotter A, Horv?th I, Lehotzky A, Tiri?n L, Medzihradszky KF, Kov?cs J, Orosz F, Ov?di J
Biochemistry45(46)13818-26(2006 Nov)

p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies.
Lindersson E, Lundvig D, Petersen C, Madsen P, Nyengaard JR, H?jrup P, Moos T, Otzen D, Gai WP, Blumbergs PC, Jensen PH
The Journal of biological chemistry280(7)5703-15(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TPPP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TPPP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu29213 NM_173846.5
Latest version!		 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu29213 XM_017020966.1
Latest version!		 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu29213 XM_005267324.4
Latest version!		 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu75212 XM_011536416.1
Latest version!		 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu75213 XM_011536420.2
Latest version!		 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu75213 XM_011536417.2
Latest version!		 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu75213 XM_011536418.1
Latest version!		 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
View Old Accession Versions >>
OHu29213 NM_173846.4 Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu29213 XM_005267324.3 Homo sapiens tubulin polymerization-promoting protein family member 2 (TPPP2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu29213
Clone ID Related Accession (Same CDS sequence) NM_173846.4 , XM_017020966.1 , NM_173846.5 , XM_005267324.3 , XM_005267324.4
Accession Version NM_173846.4 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB458250.1, BC038970.2 and AW135537.1. On Apr 10, 2009 this sequence version replaced NM_173846.3. ##Evidence-Data-START## Transcript exon combination :: AY072034.1, AY173946.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

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ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_776245.2
CDS189..701
Translation

Target ORF information:

RefSeq Version NM_173846.4
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_173846.4

ORF Insert Sequence:

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ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29213
Clone ID Related Accession (Same CDS sequence) NM_173846.4 , XM_017020966.1 , NM_173846.5 , XM_005267324.3 , XM_005267324.4
Accession Version NM_173846.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-05-01
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB458250.1, BC038970.2, AW135537.1 and AL161668.6. On Nov 23, 2018 this sequence version replaced NM_173846.4. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.146997.1, SRR5189667.197413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000321760.11/ ENSP00000317595.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

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ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_776245.2
CDS158..670
Translation

Target ORF information:

RefSeq Version NM_173846.5
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_173846.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29213
Clone ID Related Accession (Same CDS sequence) NM_173846.4 , XM_017020966.1 , NM_173846.5 , XM_005267324.3 , XM_005267324.4
Accession Version XM_017020966.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

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ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016876455.1
CDS153..665
Translation

Target ORF information:

RefSeq Version XM_017020966.1
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017020966.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29213
Clone ID Related Accession (Same CDS sequence) NM_173846.4 , XM_017020966.1 , NM_173846.5 , XM_005267324.3 , XM_005267324.4
Accession Version XM_005267324.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-03-11
Organism Homo sapiens(Human)
Product tubulin polymerization-promoting protein family member 2 isoform X1
Comment 

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ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005267381.1
Translation

Target ORF information:

RefSeq Version XM_005267324.3
Organism Homo sapiens(Human)
Definition Homo sapiens tubulin polymerization-promoting protein family member 2 (TPPP2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005267324.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29213
Clone ID Related Accession (Same CDS sequence) NM_173846.4 , XM_017020966.1 , NM_173846.5 , XM_005267324.3 , XM_005267324.4
Accession Version XM_005267324.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005267324.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

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ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005267381.1
CDS250..762
Translation

Target ORF information:

RefSeq Version XM_005267324.4
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005267324.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTAAA GCAACAACAG TGGGTGCAGT GGACCGTTTG 
ACAGACACCA GCAAGTACAC CGGCACCCAC AAGGAGCGCT TTGATGAGAG TGGCAAGGGC 
AAGGGCATTG CGGGACGGGA AGAGATGACT GACAACACAG GCTATGTGAG TGGTTACAAG 
GGTTCTGGCA CCTACGATAA GAAGACCAAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu75212
Clone ID Related Accession (Same CDS sequence) XM_011536416.1
Accession Version XM_011536416.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 474bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTTGG ATGCTCTCGT CTCGCCTGGA CAGCACACAC 
ACTCCAACTC CAGTAAGACT CAACTCAAAT ATATCTCTTA TACAACTTCA AGAGAAAAAG 
TGTGATCCCT TCTTTCGTCT AAAAGTCTGC AATAGCTTGT TTCTCATAGG GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011534718.1
CDS125..598
Translation

Target ORF information:

RefSeq Version XM_011536416.1
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011536416.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTTGG ATGCTCTCGT CTCGCCTGGA CAGCACACAC 
ACTCCAACTC CAGTAAGACT CAACTCAAAT ATATCTCTTA TACAACTTCA AGAGAAAAAG 
TGTGATCCCT TCTTTCGTCT AAAAGTCTGC AATAGCTTGT TTCTCATAGG GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu75213
Clone ID Related Accession (Same CDS sequence) XM_011536417.2 , XM_011536418.1 , XM_011536420.2
Accession Version XM_011536417.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 375bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011536417.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTCTG CTTCCAAGAA CAGGATGGAA GAATATATTT 
GGAGTAAAGA GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011534719.1
CDS125..499
Translation

Target ORF information:

RefSeq Version XM_011536417.2
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011536417.2

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTCTG CTTCCAAGAA CAGGATGGAA GAATATATTT 
GGAGTAAAGA GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu75213
Clone ID Related Accession (Same CDS sequence) XM_011536417.2 , XM_011536418.1 , XM_011536420.2
Accession Version XM_011536418.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 375bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTCTG CTTCCAAGAA CAGGATGGAA GAATATATTT 
GGAGTAAAGA GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011534720.1
CDS125..499
Translation

Target ORF information:

RefSeq Version XM_011536418.1
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011536418.1

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTCTG CTTCCAAGAA CAGGATGGAA GAATATATTT 
GGAGTAAAGA GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu75213
Clone ID Related Accession (Same CDS sequence) XM_011536417.2 , XM_011536418.1 , XM_011536420.2
Accession Version XM_011536420.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 375bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product tubulin polymerization-promoting protein family member 2 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011536420.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTCTG CTTCCAAGAA CAGGATGGAA GAATATATTT 
GGAGTAAAGA GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011534722.1
CDS125..499
Translation

Target ORF information:

RefSeq Version XM_011536420.2
Organism Homo sapiens(human)
Definition Homo sapiens tubulin polymerization promoting protein family member 2 (TPPP2), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011536420.2

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGCATCAG AGGCAGAAAA AACATTCCAT CGGTTTGCTG CGTTTGGAGA ATCATCAAGC 
AGTGGCACTG AAATGAACAA CAAGAACTTC TCCAAGCTGT GCAAAGACTG TGGCATCATG 
GATGGCAAGA CAGTCACCTC CACGGACGTG GACATCGTGT TCAGCAAAGT CAAGGCCAAG 
AACGCCCGAA CCATCACGTT TCAACAGTTC AAAGAGGCAG TGAAGGAACT GGGCCAGAAG 
CGCTTCAAAG GGAAGAGTCC AGATGAAGTC CTGGAGAACA TTTATGGACT CATGGAGGGC 
AAAGACCCAG CCACCACTGG CGCTACTCTG CTTCCAAGAA CAGGATGGAA GAATATATTT 
GGAGTAAAGA GATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions.
Biochemistry45(46)13818-26(2006 Nov)
Vincze O,T?k?si N,Ol?h J,Hlavanda E,Zotter A,Horv?th I,Lehotzky A,Tiri?n L,Medzihradszky KF,Kov?cs J,Orosz F,Ov?di J


book

p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies.
The Journal of biological chemistry280(7)5703-15(2005 Feb)
Lindersson E,Lundvig D,Petersen C,Madsen P,Nyengaard JR,H?jrup P,Moos T,Otzen D,Gai WP,Blumbergs PC,Jensen PH