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CYP4F22 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol CYP4F22
Entrez Gene ID 126410
Full Name cytochrome P450 family 4 subfamily F member 22
Synonyms ARCI5,INLNE,LI3
General protein information
Preferred Names

cytochrome P450 family 4 subfamily F member 22

Names

cytochrome P450 4F22
cytochrome P450, family 2, subfamily E, polypeptide 2 homolog
cytochrome P450, family 4, subfamily F, polypeptide 22

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

19

19p13.12

Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008].
Disorder MIM:

611495

Disorder Html: Ichthyosis, lamellar, 3, 604777 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_011527693.1 XP_011525995.1 cytochrome P450 4F22 isoform X1
XM_011527692.2 XP_011525994.1 cytochrome P450 4F22 isoform X1
NM_173483.3 NP_775754.2 cytochrome P450 4F22
XM_011527692.1 XP_011525994.1 cytochrome P450 4F22 isoform X1
XM_011527693.2 XP_011525995.1 cytochrome P450 4F22 isoform X1



Rattus norvegicus (Norway rat) Cyp4f39 XP_006241154.1
Xenopus tropicalis (tropical clawed frog) cyp4f22 NP_001015810.1
Pan troglodytes (chimpanzee) LOC455798 XP_512456.2
Bos taurus (cattle) LOC100301224 XP_005208627.1
Macaca mulatta (rhesus monkey) CYP4F22 XP_001111971.1
Mus musculus (house mouse) Cyp4f39 NP_796281.1
Arabidopsis thaliana (thale cress) CYP735A2 NP_176882.1
Xenopus tropicalis (tropical clawed frog) LOC548774 NP_001016020.1
Homo sapiens (human) CYP4F22 NP_775754.2
Canis lupus familiaris (dog) CYP4F22 XP_541984.2
Arabidopsis thaliana (thale cress) CYP735A1 NP_198661.1
Oryza sativa (rice) Os09g0403300 NP_001175823.1


Related articles in PubMed

Two Cases of Autosomal Recessive Congenital Ichthyosis due to CYP4F22 Mutations: Expanding the Genotype of Self-Healing Collodion Baby.
Noguera-Morel L, Feito-Rodríguez M, Maldonado-Cid P, García-Miñáur S, Kamsteeg EJ, González-Sarmiento R, De Lucas-Laguna R, Hernández-Martín A, Torrelo A
Pediatric dermatology33(2)e48-51(2016 Mar-Apr)

Lamellar ichthyosis in a collodion baby caused by CYP4F22 mutations in a non-consanguineous family outside the Mediterranean.
Sugiura K, Takeichi T, Tanahashi K, Ito Y, Kosho T, Saida K, Uhara H, Okuyama R, Akiyama M
Journal of dermatological science72(2)193-5(2013 Nov)

CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development.
Sasaki K, Akiyama M, Yanagi T, Sakai K, Miyamura Y, Sato M, Shimizu H
Journal of dermatological science65(2)156-8(2012 Feb)

Finding homes for orphan cytochrome P450s: CYP4V2 and CYP4F22 in disease states.
Kelly EJ, Nakano M, Rohatgi P, Yarov-Yarovoy V, Rettie AE
Molecular interventions11(2)124-32(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We report two cases of Congenital Ichthyosiform Erythroderma showing homozygous mutations in the gene CYP4F22.
Title: Two Cases of Autosomal Recessive Congenital Ichthyosis due to CYP4F22 Mutations: Expanding the Genotype of Self-Healing Collodion Baby.

description of CYP4F22 mutations from a Japanese collodion baby with lamellar ichthyosis [case report]
Title: Lamellar ichthyosis in a collodion baby caused by CYP4F22 mutations in a non-consanguineous family outside the Mediterranean.

Letter: CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development.
Title: CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development.

REVIEW: genetic analyses have identified a wide spectrum of mutations in the CYP4V2gene from patients suffering from Bietti's crystalline corneoretinal dystrophy, and mutations in theCYP4F22 gene have been linked to lamellar ichthyosis
Title: Finding homes for orphan cytochrome P450s: CYP4V2 and CYP4F22 in disease states.

The following CYP4F22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP4F22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu18711 NM_173483.3
Latest version!
Homo sapiens cytochrome P450 family 4 subfamily F member 22 (CYP4F22), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OHu18711 XM_011527693.2
Latest version!
Homo sapiens cytochrome P450 family 4 subfamily F member 22 (CYP4F22), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OHu18711 XM_011527692.2
Latest version!
Homo sapiens cytochrome P450 family 4 subfamily F member 22 (CYP4F22), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
View Old Accession Versions >>
OHu18711 XM_011527692.1 Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 (CYP4F22), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OHu18711 XM_011527693.1 Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 (CYP4F22), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu18711
Clone ID Related Accession (Same CDS sequence) XM_011527693.1 , XM_011527692.2 , NM_173483.3 , XM_011527692.1 , XM_011527693.2
Accession Version NM_173483.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1596bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-30
Organism Homo sapiens(Human)
Product cytochrome P450 4F22
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA874258.1, BC069351.1, AC011492.8 and AI341068.1. This sequence is a reference standard in the RefSeqGene project. On Oct 11, 2007 this sequence version replaced NM_173483.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK096820.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

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ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_775754.2
CDS168..1763
Misc Feature(1)93..95
Misc Feature(2)345..1739
Exon (1)1..59
Exon (2)60..166
Exon (3)167..389
Exon (4)390..534
Exon (5)535..588
Exon (6)589..716
Exon (7)717..838
Exon (8)839..1106
Exon (9)1107..1173
Exon (10)1174..1303
Exon (11)1304..1437
Exon (12)1438..1502
Exon (13)1503..1585
Exon (14)1586..2609
Translation

Target ORF information:

RefSeq Version NM_173483.3
Organism Homo sapiens(Human)
Definition Homo sapiens cytochrome P450 family 4 subfamily F member 22 (CYP4F22), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_173483.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18711
Clone ID Related Accession (Same CDS sequence) XM_011527693.1 , XM_011527692.2 , NM_173483.3 , XM_011527692.1 , XM_011527693.2
Accession Version XM_011527693.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1596bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product cytochrome P450 4F22 isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011525995.1
Translation

Target ORF information:

RefSeq Version XM_011527693.1
Organism Homo sapiens(Human)
Definition Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 (CYP4F22), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011527693.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18711
Clone ID Related Accession (Same CDS sequence) XM_011527693.1 , XM_011527692.2 , NM_173483.3 , XM_011527692.1 , XM_011527693.2
Accession Version XM_011527692.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1596bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product cytochrome P450 4F22 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527692.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011525994.1
CDS410..2005
Misc Feature(1)587..1981
Translation

Target ORF information:

RefSeq Version XM_011527692.2
Organism Homo sapiens(Human)
Definition Homo sapiens cytochrome P450 family 4 subfamily F member 22 (CYP4F22), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011527692.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18711
Clone ID Related Accession (Same CDS sequence) XM_011527693.1 , XM_011527692.2 , NM_173483.3 , XM_011527692.1 , XM_011527693.2
Accession Version XM_011527692.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1596bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product cytochrome P450 4F22 isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011525994.1
Translation

Target ORF information:

RefSeq Version XM_011527692.1
Organism Homo sapiens(Human)
Definition Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 (CYP4F22), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011527692.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18711
Clone ID Related Accession (Same CDS sequence) XM_011527693.1 , XM_011527692.2 , NM_173483.3 , XM_011527692.1 , XM_011527693.2
Accession Version XM_011527693.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1596bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product cytochrome P450 4F22 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527693.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011525995.1
CDS180..1775
Misc Feature(1)357..1751
Translation

Target ORF information:

RefSeq Version XM_011527693.2
Organism Homo sapiens(Human)
Definition Homo sapiens cytochrome P450 family 4 subfamily F member 22 (CYP4F22), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011527693.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCTGCCCA TCACAGACCG CCTGCTGCAC CTCCTGGGGC TGGAGAAGAC GGCGTTCCGC 
ATATACGCGG TGTCCACCCT TCTCCTCTTC CTGCTCTTCT TCCTGTTCCG CCTGCTGCTG
CGGTTCCTGA GGCTCTGCAG GAGCTTCTAC ATCACCTGCC GCCGGCTGCG CTGCTTCCCC
CAGCCTCCCC GGCGCAACTG GCTGCTGGGC CACCTGGGCA TGTACCTTCC AAATGAGGCG
GGCCTTCAAG ATGAGAAGAA GGTACTGGAC AACATGCACC ATGTACTCTT GGTATGGATG
GGACCTGTCC TGCCGCTGTT GGTTCTGGTG CACCCTGATT ACATCAAACC CCTTTTGGGA
GCCTCAGCTG CCATCGCCCC CAAGGATGAC CTCTTCTATG GCTTCCTAAA ACCTTGGCTA
GGGGATGGGC TGCTGCTCAG CAAAGGTGAC AAGTGGAGCC GGCACCGTCG CCTGCTGACA
CCCGCCTTCC ACTTTGACAT CCTGAAGCCT TACATGAAGA TCTTCAACCA GAGCGCTGAC
ATTATGCATG CTAAATGGCG GCATCTGGCA GAGGGCTCAG CGGTCTCCCT TGATATGTTT
GAGCATATCA GCCTCATGAC CCTGGACAGT CTTCAGAAAT GTGTCTTCAG CTACAACAGC
AACTGCCAAG AGAAGATGAG TGATTATATC TCCGCTATCA TTGAACTGAG CGCTCTGTCT
GTCCGGCGCC AGTATCGCTT GCACCACTAC CTCGACTTCA TTTACTACCG CTCGGCGGAT
GGGCGGAGGT TCCGGCAGGC CTGTGACATG GTGCACCACT TCACCACTGA AGTCATCCAG
GAACGGCGGC GGGCACTGCG TCAGCAGGGG GCCGAGGCCT GGCTTAAGGC CAAGCAGGGG
AAGACCTTGG ACTTTATTGA TGTGCTGCTC CTGGCCAGGG ATGAAGATGG AAAGGAACTG
TCAGACGAGG ATATCCGAGC CGAAGCAGAC ACCTTCATGT TTGAGGGTCA CGACACAACA
TCCAGTGGGA TCTCTTGGAT GCTGTTCAAT TTGGCAAAGT ATCCGGAATA CCAGGAGAAA
TGCCGAGAAG AGATTCAGGA AGTCATGAAA GGCCGGGAGC TGGAGGAGCT GGAGTGGGAC
GATCTGACTC AGCTGCCCTT TACAACTATG TGCATTAAGG AGAGCCTGCG CCAGTACCCA
CCTGTCACTC TTGTCTCTCG CCAATGCACG GAGGACATCA AGCTCCCAGA TGGGCGCATC
ATCCCCAAAG GAATCATCTG CTTGGTCAGC ATCTATGGAA CCCACCACAA CCCCACAGTG
TGGCCTGACT CCAAGGTGTA CAACCCCTAC CGCTTTGACC CGGACAACCC ACAGCAGCGC
TCTCCACTGG CCTATGTGCC CTTCTCTGCA GGACCCAGGA ATTGCATCGG ACAGAGCTTC
GCCATGGCCG AGTTGCGCGT GGTTGTGGCA CTAACACTGC TACGTTTCCG CCTGAGCGTG
GACCGAACGC GCAAGGTGCG GCGGAAGCCG GAGCTCATAC TGCGCACGGA GAACGGGCTC
TGGCTCAAGG TGGAGCCGCT GCCTCCGCGG GCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Two Cases of Autosomal Recessive Congenital Ichthyosis due to CYP4F22 Mutations: Expanding the Genotype of Self-Healing Collodion Baby.
Pediatric dermatology33(2)e48-51(2016 Mar-Apr)
Noguera-Morel L,Feito-Rodríguez M,Maldonado-Cid P,García-Miñáur S,Kamsteeg EJ,González-Sarmiento R,De Lucas-Laguna R,Hernández-Martín A,Torrelo A


book

Lamellar ichthyosis in a collodion baby caused by CYP4F22 mutations in a non-consanguineous family outside the Mediterranean.
Journal of dermatological science72(2)193-5(2013 Nov)
Sugiura K,Takeichi T,Tanahashi K,Ito Y,Kosho T,Saida K,Uhara H,Okuyama R,Akiyama M


book

CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development.
Journal of dermatological science65(2)156-8(2012 Feb)
Sasaki K,Akiyama M,Yanagi T,Sakai K,Miyamura Y,Sato M,Shimizu H


book

Finding homes for orphan cytochrome P450s: CYP4V2 and CYP4F22 in disease states.
Molecular interventions11(2)124-32(2011 Apr)
Kelly EJ,Nakano M,Rohatgi P,Yarov-Yarovoy V,Rettie AE


 
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