Gene Symbol | AFAP1L1 |
Entrez Gene ID | 134265 |
Full Name | actin filament associated protein 1 like 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » AFAP1L1 cDNA ORF clone
Gene Symbol | AFAP1L1 |
Entrez Gene ID | 134265 |
Full Name | actin filament associated protein 1 like 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_152406.2 | NP_689619.1 | actin filament-associated protein 1-like 1 isoform 1 |
NM_152406.3 | NP_689619.1 | actin filament-associated protein 1-like 1 isoform 1 |
NM_001146337.3 | NP_001139809.1 | actin filament-associated protein 1-like 1 isoform 2 |
XM_017009036.1 | XP_016864525.1 | actin filament-associated protein 1-like 1 isoform X1 |
NM_152406.4 | NP_689619.1 | actin filament-associated protein 1-like 1 isoform 1 |
XM_011537558.2 | XP_011535860.1 | actin filament-associated protein 1-like 1 isoform X2 |
NM_001323063.1 | NP_001309992.1 | actin filament-associated protein 1-like 1 isoform 4 |
XM_011537558.1 | XP_011535860.1 | actin filament-associated protein 1-like 1 isoform X2 |
NM_001323062.1 | NP_001309991.1 | actin filament-associated protein 1-like 1 isoform 3 |
NM_001146337.2 | NP_001139809.1 | actin filament-associated protein 1-like 1 isoform 2 |
NM_001323062.2 | NP_001309991.1 | actin filament-associated protein 1-like 1 isoform 3 |
Xenopus tropicalis (tropical clawed frog) | afap1l1 | XP_002939152.2 |
Bos taurus (cattle) | AFAP1L1 | NP_001093804.1 |
Gallus gallus (chicken) | AFAP1L1 | XP_425193.3 |
Homo sapiens (human) | AFAP1L1 | NP_689619.1 |
Canis lupus familiaris (dog) | AFAP1L1 | XP_005619510.1 |
Pan troglodytes (chimpanzee) | AFAP1L1 | XP_518027.3 |
AFAP1L1 | XP_002804621.1 | |
Mus musculus (house mouse) | Afap1l1 | NP_849259.2 |
Rattus norvegicus (Norway rat) | Afap1l1 | NP_001099612.1 |
Actin Filament-Associated Protein 1-Like 1 Mediates Proliferation and Survival in Non-Small Cell Lung Cancer Cells.
Wang M, Han X, Sun W, Li X, Jing G, Zhang X
Medical science monitor : international medical journal of experimental and clinical research24215-224(2018 Jan)
Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway.
Tie SR, McCarthy DJ, Kendrick TS, Louw A, Le C, Satiaputra J, Kucera N, Phillips M, Ingley E
Oncogene35(16)2098-111(2016 Apr)
AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers.
Takahashi R, Nagayama S, Furu M, Kajita Y, Jin Y, Kato T, Imoto S, Sakai Y, Toguchida J
Cancer medicine3(4)759-74(2014 Aug)
The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
Kajita Y, Kato T Jr, Tamaki S, Furu M, Takahashi R, Nagayama S, Aoyama T, Nishiyama H, Nakamura E, Katagiri T, Nakamura Y, Ogawa O, Toguchida J
PloS one8(1)e49709(2013)
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
data define a novel pathway that directs Lyn/Src family tyrosine kinase signals to sarcoma cell invadopodia through specific recruitment of Vav2 and Nck2 to phosphorylated AFAP1L1, to control cell migration and invasion
Title: Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway.
AFAP1L1 plays a role in the progression of colorectal cancer by modulating cell shape and motility and by inhibiting anoikis, presumably through interactions with vinculin-including protein complexes.
Title: AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers.
Findings indicate a role for transcription factor Sp3 in sarcomas as a driver for expression of the metastasis-related gene AFAP1L1 (actin filament-associated protein 1-like 1).
Title: The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
AFAP1L1 has a role in the progression of spindle cell sarcomas and is a prognostic biomarker.
Title: Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas.
Data suggest that AFAP1L1 may forge unique protein interactions in which AFAP1 is less efficient, and these interactions may allow AFAP1L1 to affect invadosome formation.
Title: AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes.
The following AFAP1L1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AFAP1L1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu12430 | |
Clone ID Related Accession (Same CDS sequence) | NM_152406.2 , NM_152406.3 , NM_152406.4 | |
Accession Version | NM_152406.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-14 | |
Organism | Homo sapiens(Human) | |
Product | actin filament-associated protein 1-like 1 isoform 1 | |
Comment |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_689619.1 |
Translation |
Target ORF information:
Target ORF information:
|
NM_152406.2 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12430 | |
Clone ID Related Accession (Same CDS sequence) | NM_152406.2 , NM_152406.3 , NM_152406.4 | |
Accession Version | NM_152406.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-13 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA792192.1, BC125093.1, AK074185.1, AC131025.1 and BX107758.1. On Apr 16, 2016 this sequence version replaced NM_152406.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK074185.1, SRR1803613.172483.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_689619.1 |
CDS | 132..2438 |
Translation |
Target ORF information:
Target ORF information:
|
NM_152406.3 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12430 | |
Clone ID Related Accession (Same CDS sequence) | NM_152406.2 , NM_152406.3 , NM_152406.4 | |
Accession Version | NM_152406.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-29 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA792192.1, BC125093.1, AK074185.1, AC131025.1 and BX107758.1. On Nov 23, 2018 this sequence version replaced NM_152406.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK074185.1, SRR1803613.172483.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000296721.9/ ENSP00000296721.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_689619.1 |
CDS | 111..2417 |
Translation |
Target ORF information:
Target ORF information:
|
NM_152406.4 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu75735 | |
Clone ID Related Accession (Same CDS sequence) | XM_011537558.2 , XM_011537558.1 | |
Accession Version | XM_011537558.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1887bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011537558.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCTTG GATCAGATGG CTGCAGCCCC TCACACTCGA TTGTGGATGG CTACTATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011535860.1 |
CDS | 111..1997 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011537558.2 |
1 | ATGGTGCTTG GATCAGATGG CTGCAGCCCC TCACACTCGA TTGTGGATGG CTACTATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu75735 | |
Clone ID Related Accession (Same CDS sequence) | XM_011537558.2 , XM_011537558.1 | |
Accession Version | XM_011537558.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1887bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCTTG GATCAGATGG CTGCAGCCCC TCACACTCGA TTGTGGATGG CTACTATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011535860.1 |
CDS | 102..1988 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011537558.1 |
1 | ATGGTGCTTG GATCAGATGG CTGCAGCCCC TCACACTCGA TTGTGGATGG CTACTATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100402 | |
Clone ID Related Accession (Same CDS sequence) | NM_001323063.1 | |
Accession Version | NM_001323063.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-29 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA792192.1, BC040723.2 and AC131025.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC040723.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001309992.1 |
CDS | 132..1265 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001323063.1 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu95655 | |
Clone ID Related Accession (Same CDS sequence) | XM_017009036.1 | |
Accession Version | XM_017009036.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCGTGG CCTCCATCCT GCAGAGCCTG CAGCCCCTTC CAGCAAAGGA GGTCTCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016864525.1 |
CDS | 211..2415 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017009036.1 |
1 | ATGGCCGTGG CCTCCATCCT GCAGAGCCTG CAGCCCCTTC CAGCAAAGGA GGTCTCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu11195 | |
Clone ID Related Accession (Same CDS sequence) | NM_001146337.3 , NM_001146337.2 | |
Accession Version | NM_001146337.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2178bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-08 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA792192.1, BC125093.1, BC125094.1, AK074185.1, AC131025.1 and BX107758.1. On May 31, 2019 this sequence version replaced NM_001146337.2. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC125094.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153031, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001139809.1 |
CDS | 111..2288 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001146337.3 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu11195 | |
Clone ID Related Accession (Same CDS sequence) | NM_001146337.3 , NM_001146337.2 | |
Accession Version | NM_001146337.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2178bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-24 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA792192.1, BC125093.1, BC125094.1, AK074185.1, AC131025.1 and BX107758.1. On Apr 16, 2016 this sequence version replaced NM_001146337.1. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC125094.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153031, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001139809.1 |
CDS | 132..2309 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001146337.2 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu39817 | |
Clone ID Related Accession (Same CDS sequence) | NM_001323062.1 , NM_001323062.2 | |
Accession Version | NM_001323062.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-12-04 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA792192.1, BC125093.1, AK074185.1, AC131025.1 and BX107758.1. On Apr 16, 2016 this sequence version replaced XM_005268373.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.98295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001309991.1 |
CDS | 132..2339 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001323062.1 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu39817 | |
Clone ID Related Accession (Same CDS sequence) | NM_001323062.1 , NM_001323062.2 | |
Accession Version | NM_001323062.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-08 | |
Organism | Homo sapiens(human) | |
Product | actin filament-associated protein 1-like 1 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA792192.1, BC125093.1, AK074185.1, AC131025.1 and BX107758.1. On May 31, 2019 this sequence version replaced NM_001323062.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.98295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001309991.1 |
CDS | 111..2318 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001323062.2 |
1 | ATGGACCGAG GCCAGGTGCT GGAGCAGCTG CTCCCAGAGC TCACCGGGCT GCTCAGCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Actin Filament-Associated Protein 1-Like 1 Mediates Proliferation and Survival in Non-Small Cell Lung Cancer Cells. |
Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway. |
AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers. |
The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1). |
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. |