| Gene Symbol | COX8A |
| Entrez Gene ID | 1351 |
| Full Name | cytochrome c oxidase subunit 8A |
| Synonyms | COX,COX8,COX8-2,COX8L,VIII,VIII-L |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | ?Mitochondrial complex IV deficiency, 220110 (3) |

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