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MACROD2 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol MACROD2
Entrez Gene ID 140733
Full Name MACRO domain containing 2
Synonyms C20orf133,C2orf133
General protein information
Preferred Names

MACRO domain containing 2

Names

O-acetyl-ADP-ribose deacetylase MACROD2
MACRO domain-containing protein 2
[Protein ADP-ribosylglutamate] hydrolase

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

20

20p12.1

Disorder MIM:

611567


mRNA and Protein(s)

mRNA Protein Name
XM_017027677.1 XP_016883166.1 O-acetyl-ADP-ribose deacetylase MACROD2 isoform X3
NM_001033087.1 NP_001028259.1 O-acetyl-ADP-ribose deacetylase MACROD2 isoform 2
XM_017027676.1 XP_016883165.1 O-acetyl-ADP-ribose deacetylase MACROD2 isoform X2
NM_080676.5 NP_542407.2 O-acetyl-ADP-ribose deacetylase MACROD2 isoform 1
XM_017027675.1 XP_016883164.1 O-acetyl-ADP-ribose deacetylase MACROD2 isoform X1



Pan troglodytes (chimpanzee) MACROD2 XP_001136712.1
Mus musculus (house mouse) Macrod2 NP_001013824.2
Canis lupus familiaris (dog) MACROD2 XP_003433240.1
Caenorhabditis elegans (roundworm) B0035.3 NP_502127.1
Xenopus tropicalis (tropical clawed frog) macrod2 XP_004914776.1
Gallus gallus (chicken) LOC421259 XP_429829.2
Arabidopsis thaliana (thale cress) AT2G40600 NP_030605.2
Homo sapiens (human) MACROD2 NP_542407.2
Rattus norvegicus (Norway rat) Macrod2 XP_006235176.1
Oryza sativa (rice) Os03g0336500 NP_001050042.2
Macaca mulatta (rhesus monkey) MACROD2 XP_002798269.1


Related articles in PubMed

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.
Mohseni M, Cidado J, Croessmann S, Cravero K, Cimino-Mathews A, Wong HY, Scharpf R, Zabransky DJ, Abukhdeir AM, Garay JP, Wang GM, Beaver JA, Cochran RL, Blair BG, Rosen DM, Erlanger B, Argani P, Hurley PJ, Lauring J, Park BH
Proceedings of the National Academy of Sciences of the United States of America111(49)17606-11(2014 Dec)

MACROD2 gene associated with autistic-like traits in a general population sample.
Jones RM, Cadby G, Blangero J, Abraham LJ, Whitehouse AJO, Moses EK
Psychiatric genetics24(6)241-248(2014 Dec)

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.
Xie T, Deng L, Mei P, Zhou Y, Wang B, Zhang J, Lin J, Wei Y, Zhang X, Xu R
Neurobiology of aging35(7)1778.e9-1778.e23(2014 Jul)

Genetic variants associated with disordered eating.
Wade TD, Gordon S, Medland S, Bulik CM, Heath AC, Montgomery GW, Martin NG
The International journal of eating disorders46(6)594-608(2013 Sep)

Genome-wide association study of antiphospholipid antibodies.
Kamboh MI, Wang X, Kao AH, Barmada MM, Clarke A, Ramsey-Goldman R, Manzi S, Demirci FY
Autoimmune diseases2013761046(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ATM induces MacroD2 nuclear export upon DNA damage.
Title: ATM induces MacroD2 nuclear export upon DNA damage.

In patients with Graves' disease, a common genetic variant in MACROD2 may increase susceptibility for thyroid-associated orbitopathy.
Title: Association of Polymorphisms in MACRO Domain Containing 2 With Thyroid-Associated Orbitopathy.

MACROD2 is a key mediator of estrogen independent growth and tamoxifen resistance
Title: MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.

MACROD2 gene is a strong positional candidate risk factor for autistic-like traits in the general population
Title: MACROD2 gene associated with autistic-like traits in a general population sample.

this study does not provide support for the reported association between rs4141463, within the MACROD2 gene and autism.
Title: No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 gene and autism spectrum disorder.

The following MACROD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MACROD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu13883 NM_001033087.1
Latest version!
Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu13934 NM_080676.5
Latest version!
Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $251.30
$359.00
OHu92923 XM_017027675.1
Latest version!
Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
OHu92924 XM_017027676.1
Latest version!
Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
OHu92925 XM_017027677.1
Latest version!
Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $223.30
$319.00

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All Other ORF Clones
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu13883
Clone ID Related Accession (Same CDS sequence) NM_001033087.1
Accession Version NM_001033087.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 642bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-27
Organism Homo sapiens(Human)
Product O-acetyl-ADP-ribose deacetylase MACROD2 isoform 2
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC018687.1, AL133462.23 and AL136991.26. Transcript Variant: This variant (2) has multiple differences in the presence and absence of exons, compared to variant 1. These differences cause translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus and a unique internal segment, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC018687.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA2142363 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
ATGAATGAGT TTTTCTCCGT AGACGATAAT AATGAAGAAG AAGAGGATGT TGAAATGAAA 
GAAGATTCAG ATGAGAACGG TCCAGAGGAG AAGCAAAGTG TGGAAGAAAT GGAAGAGCAG
AGCCAAGATG CAGATGGTGT CAACACTGTC ACTGTGCCCG GCCCTGCTTC AGAAGAGGCA
GTTGAAGACT GTAAAGATGA AGATTTTGCA AAGGATGAAA ATATTACAAA AGGCGGTGAA
GTGACAGATC ATTCTGTGCG TGACCAAGAT CATCCCGATG GACAAGAGAA TGATTCAACG
AAGAATGAAA TAAAAATTGA AACAGAATCG CAGAGCTCAT ATATGGAAAC AGAAGAACTT
TCATCAAACC AAGAAGATGC CGTGATTGTG GAGCAACCAG AAGTGATTCC ATTAACAGAG
GACCAAGAAG AAAAAGAAGG TGAAAAAGCT CCAGGCGAGG ACACACCTAG GATGCCTGGG
AAAAGTGAAG GCTCCAGTGA CCTAGAAAAT ACTCCAGGTC CTGATGTTGA AATGAATAGT
CAGGTTGACA AGGTAAATGA CCCAACAGAG AGTCAACAAG AAGATCAACT AATAGCAGGG
GCACAAGATG AAGCGAAGGA ACAAAGAAAT GGAACTAAAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001028259.1
CDS463..1104
Misc Feature(1)82..84
Exon (1)1..175
Exon (2)176..297
Exon (3)298..328
Exon (4)329..402
Exon (5)403..484
Exon (6)485..532
Exon (7)533..595
Exon (8)596..664
Exon (9)665..742
Exon (10)743..817
Exon (11)818..910
Exon (12)911..988
Exon (13)989..1057
Exon (14)1058..4425
Translation

Target ORF information:

RefSeq Version NM_001033087.1
Organism Homo sapiens(Human)
Definition Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001033087.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGAATGAGT TTTTCTCCGT AGACGATAAT AATGAAGAAG AAGAGGATGT TGAAATGAAA 
GAAGATTCAG ATGAGAACGG TCCAGAGGAG AAGCAAAGTG TGGAAGAAAT GGAAGAGCAG
AGCCAAGATG CAGATGGTGT CAACACTGTC ACTGTGCCCG GCCCTGCTTC AGAAGAGGCA
GTTGAAGACT GTAAAGATGA AGATTTTGCA AAGGATGAAA ATATTACAAA AGGCGGTGAA
GTGACAGATC ATTCTGTGCG TGACCAAGAT CATCCCGATG GACAAGAGAA TGATTCAACG
AAGAATGAAA TAAAAATTGA AACAGAATCG CAGAGCTCAT ATATGGAAAC AGAAGAACTT
TCATCAAACC AAGAAGATGC CGTGATTGTG GAGCAACCAG AAGTGATTCC ATTAACAGAG
GACCAAGAAG AAAAAGAAGG TGAAAAAGCT CCAGGCGAGG ACACACCTAG GATGCCTGGG
AAAAGTGAAG GCTCCAGTGA CCTAGAAAAT ACTCCAGGTC CTGATGTTGA AATGAATAGT
CAGGTTGACA AGGTAAATGA CCCAACAGAG AGTCAACAAG AAGATCAACT AATAGCAGGG
GCACAAGATG AAGCGAAGGA ACAAAGAAAT GGAACTAAAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu13934
Clone ID Related Accession (Same CDS sequence) NM_080676.5
Accession Version NM_080676.5 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1278bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-28
Organism Homo sapiens(Human)
Product O-acetyl-ADP-ribose deacetylase MACROD2 isoform 1
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB125529.1, DB495787.2, DR001087.1, AK125899.1 and AL136991.26. On or before Nov 15, 2006 this sequence version replaced NM_001033086.1, NM_080676.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK131348.1, SRR1803612.286790.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03568911 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTACCCCA GCAACAAGAA GAAAAAGGTG TGGAGAGAGG AGAAAGAACG TTTATTGAAG 
ATGACCTTAG AAGAGAGACG CAAAGAATAC CTAAGAGACT ATATTCCCCT GAACAGCATT
CTATCATGGA AGGAGGAGAT GAAGGGCAAG GGCCAAAATG ATGAAGAAAA TACTCAGGAA
ACATCCCAGG TGAAGAAAAG TTTGACTGAA AAAGTTTCTC TCTATAGAGG TGACATCACA
TTGCTAGAGG TAGATGCTAT AGTCAATGCC GCAAATGCCA GTCTTCTTGG AGGAGGAGGT
GTGGATGGCT GTATTCATAG AGCAGCCGGC CCCTGTTTGC TAGCTGAATG TCGTAACCTG
AATGGCTGTG ATACTGGACA TGCAAAAATC ACATGTGGCT ATGACCTTCC TGCAAAATAT
GTCATCCATA CTGTAGGGCC AATAGCCAGG GGCCATATTA ATGGTTCCCA CAAGGAAGAC
CTTGCAAATT GCTATAAATC ATCTCTGAAG CTCGTGAAAG AAAATAACAT CCGATCAGTT
GCATTTCCCT GCATCTCAAC AGGCATTTAT GGCTTTCCCA ACGAGCCTGC TGCAGTCATT
GCCCTCAACA CCATTAAGGA ATGGCTTGCC AAGAATCACC ATGAGGTGGA TCGGATCATT
TTCTGTGTCT TCTTAGAAGT TGACTTCAAA ATCTACAAAA AGAAAATGAA TGAGTTTTTC
TCCGTAGACG ATAATAATGA AGAAGAAGAG GATGTTGAAA TGAAAGAAGA TTCAGATGAG
AACGGTCCAG AGGAGAAGCA AAGTGTGGAA GAAATGGAAG AGCAGAGCCA AGATGCAGAT
GGTGTCAACA CTGTCACTGT GCCCGGCCCT GCTTCAGAAG AGGCAGTTGA AGACTGTAAA
GATGAAGATT TTGCAAAGGA TGAAAATATT ACAAAAGGCG GTGAAGTGAC AGATCATTCT
GTGCGTGACC AAGATCATCC CGATGGACAA GAGAATGATT CAACGAAGAA TGAAATAAAA
ATTGAAACAG AATCGCAGAG CTCATATATG GAAACAGAAG AACTTTCATC AAACCAAGAA
GATGCCGTGA TTGTGGAGCA ACCAGAAGTG ATTCCATTAA CAGAGGACCA AGAAGAAAAA
GAAGGTGAAA AAGCTCCAGG CGAGGACACA CCTAGGATGC CTGGGAAAAG TGAAGGCTCC
AGTGACCTAG AAAATACTCC AGGTCCTGAT GCAGGGGCAC AAGATGAAGC GAAGGAACAA
AGAAATGGAA CTAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_542407.2
CDS265..1542
Misc Feature(1)169..171
Misc Feature(2)469..981
Misc Feature(3)475..975
Misc Feature(4)order(496..501,538..540,559..561,565..570,820..822,826..834)
Misc Feature(5)order(529..531,538..540,556..558,568..570,691..693)
Exon (1)1..310
Exon (2)311..427
Exon (3)428..535
Exon (4)536..565
Exon (5)566..682
Exon (6)683..804
Exon (7)805..835
Exon (8)836..909
Exon (9)910..991
Exon (10)992..1039
Exon (11)1040..1102
Exon (12)1103..1171
Exon (13)1172..1249
Exon (14)1250..1324
Exon (15)1325..1417
Exon (16)1418..1495
Exon (17)1496..4863
Translation

Target ORF information:

RefSeq Version NM_080676.5
Organism Homo sapiens(Human)
Definition Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_080676.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTACCCCA GCAACAAGAA GAAAAAGGTG TGGAGAGAGG AGAAAGAACG TTTATTGAAG 
ATGACCTTAG AAGAGAGACG CAAAGAATAC CTAAGAGACT ATATTCCCCT GAACAGCATT
CTATCATGGA AGGAGGAGAT GAAGGGCAAG GGCCAAAATG ATGAAGAAAA TACTCAGGAA
ACATCCCAGG TGAAGAAAAG TTTGACTGAA AAAGTTTCTC TCTATAGAGG TGACATCACA
TTGCTAGAGG TAGATGCTAT AGTCAATGCC GCAAATGCCA GTCTTCTTGG AGGAGGAGGT
GTGGATGGCT GTATTCATAG AGCAGCCGGC CCCTGTTTGC TAGCTGAATG TCGTAACCTG
AATGGCTGTG ATACTGGACA TGCAAAAATC ACATGTGGCT ATGACCTTCC TGCAAAATAT
GTCATCCATA CTGTAGGGCC AATAGCCAGG GGCCATATTA ATGGTTCCCA CAAGGAAGAC
CTTGCAAATT GCTATAAATC ATCTCTGAAG CTCGTGAAAG AAAATAACAT CCGATCAGTT
GCATTTCCCT GCATCTCAAC AGGCATTTAT GGCTTTCCCA ACGAGCCTGC TGCAGTCATT
GCCCTCAACA CCATTAAGGA ATGGCTTGCC AAGAATCACC ATGAGGTGGA TCGGATCATT
TTCTGTGTCT TCTTAGAAGT TGACTTCAAA ATCTACAAAA AGAAAATGAA TGAGTTTTTC
TCCGTAGACG ATAATAATGA AGAAGAAGAG GATGTTGAAA TGAAAGAAGA TTCAGATGAG
AACGGTCCAG AGGAGAAGCA AAGTGTGGAA GAAATGGAAG AGCAGAGCCA AGATGCAGAT
GGTGTCAACA CTGTCACTGT GCCCGGCCCT GCTTCAGAAG AGGCAGTTGA AGACTGTAAA
GATGAAGATT TTGCAAAGGA TGAAAATATT ACAAAAGGCG GTGAAGTGAC AGATCATTCT
GTGCGTGACC AAGATCATCC CGATGGACAA GAGAATGATT CAACGAAGAA TGAAATAAAA
ATTGAAACAG AATCGCAGAG CTCATATATG GAAACAGAAG AACTTTCATC AAACCAAGAA
GATGCCGTGA TTGTGGAGCA ACCAGAAGTG ATTCCATTAA CAGAGGACCA AGAAGAAAAA
GAAGGTGAAA AAGCTCCAGG CGAGGACACA CCTAGGATGC CTGGGAAAAG TGAAGGCTCC
AGTGACCTAG AAAATACTCC AGGTCCTGAT GCAGGGGCAC AAGATGAAGC GAAGGAACAA
AGAAATGGAA CTAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu92923
Clone ID Related Accession (Same CDS sequence) XM_017027675.1
Accession Version XM_017027675.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product O-acetyl-ADP-ribose deacetylase MACROD2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAATGAGT TTTTCTCCGT AGACGATAAT AATGAAGAAG AAGAGGATGT TGAAATGAAA 
GAAGATTCAG AAAGTAATGA CTTTGGTGGA CAAGAGGCAG TTGGAGGTTA TCTTAACAGA
GGATCAAGCC AATTCCTACA CTACAAGGGT AATCACTCCG CAATGAGTTC AGATGAGAAC
GGTCCAGAGG AGAAGCAAAG TGTGGAAGAA ATGGAAGAGC AGAGCCAAGA TGCAGATGGT
GTCAACACTG TCACTGTGCC CGGCCCTGCT TCAGAAGAGG CAGTTGAAGA CTGTAAAGAT
GAAGATTTTG CAAAGGATGA AAATATTACA AAAGGCGGTG AAGTGACAGA TCATTCTGTG
CGTGACCAAG ATCATCCCGA TGGACAAGAG AATGATTCAA CGAAGAATGA AATAAAAATT
GAAACAGAAT CGCAGAGCTC ATATATGGAA ACAGAAGAAC TTTCATCAAA CCAAGAAGAT
GCCGTGATTG TGGAGCAACC AGAAGTGATT CCATTAACAG AGGACCAAGA AGAAAAAGAA
GGTGAAAAAG CTCCAGGCGA GGACACACCT AGGATGCCTG GGAAAAGTGA AGGCTCCAGT
GACCTAGAAA ATACTCCAGG TCCTGATGTT GAAATGAATA GTCAGGTTGA CAAGGTAAAT
GACCCAACAG AGAGTCAACA AGAAGATCAA CTAATAGCAG GGGCACAAGA TGAAGCGAAG
GAACAAAGAA ATGGAACTAA ATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016883164.1
CDS5..748
Translation

Target ORF information:

RefSeq Version XM_017027675.1
Organism Homo sapiens(Human)
Definition Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017027675.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAATGAGT TTTTCTCCGT AGACGATAAT AATGAAGAAG AAGAGGATGT TGAAATGAAA 
GAAGATTCAG AAAGTAATGA CTTTGGTGGA CAAGAGGCAG TTGGAGGTTA TCTTAACAGA
GGATCAAGCC AATTCCTACA CTACAAGGGT AATCACTCCG CAATGAGTTC AGATGAGAAC
GGTCCAGAGG AGAAGCAAAG TGTGGAAGAA ATGGAAGAGC AGAGCCAAGA TGCAGATGGT
GTCAACACTG TCACTGTGCC CGGCCCTGCT TCAGAAGAGG CAGTTGAAGA CTGTAAAGAT
GAAGATTTTG CAAAGGATGA AAATATTACA AAAGGCGGTG AAGTGACAGA TCATTCTGTG
CGTGACCAAG ATCATCCCGA TGGACAAGAG AATGATTCAA CGAAGAATGA AATAAAAATT
GAAACAGAAT CGCAGAGCTC ATATATGGAA ACAGAAGAAC TTTCATCAAA CCAAGAAGAT
GCCGTGATTG TGGAGCAACC AGAAGTGATT CCATTAACAG AGGACCAAGA AGAAAAAGAA
GGTGAAAAAG CTCCAGGCGA GGACACACCT AGGATGCCTG GGAAAAGTGA AGGCTCCAGT
GACCTAGAAA ATACTCCAGG TCCTGATGTT GAAATGAATA GTCAGGTTGA CAAGGTAAAT
GACCCAACAG AGAGTCAACA AGAAGATCAA CTAATAGCAG GGGCACAAGA TGAAGCGAAG
GAACAAAGAA ATGGAACTAA ATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu92924
Clone ID Related Accession (Same CDS sequence) XM_017027676.1
Accession Version XM_017027676.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 675bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product O-acetyl-ADP-ribose deacetylase MACROD2 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGAATGAGT TTTTCTCCGT AGACGATAAT AATGAAGAAG AAGAGGATGT TGAAATGAAA 
GAAGATTCAG AAAGTAATGA CTTTGGTGGA CAAGAGGCAG TTGGAGGTTA TCTTAACAGA
GGATCAAGCC AATTCCTACA CTACAAGGGT AATCACTCCG CAATGAGTTC AGATGAGAAC
GGTCCAGAGG AGAAGCAAAG TGTGGAAGAA ATGGAAGAGC AGAGCCAAGA TGCAGATGGT
GTCAACACTG TCACTGTGCC CGGCCCTGCT TCAGAAGAGG CAGTTGAAGA CTGTAAAGAT
GAAGATTTTG CAAAGGATGA AAATATTACA AAAGGCGGTG AAGTGACAGA TCATTCTGTG
CGTGACCAAG ATCATCCCGA TGGACAAGAG AATGATTCAA CGAAGAATGA AATAAAAATT
GAAACAGAAT CGCAGAGCTC ATATATGGAA ACAGAAGAAC TTTCATCAAA CCAAGAAGAT
GCCGTGATTG TGGAGCAACC AGAAGTGATT CCATTAACAG AGGACCAAGA AGAAAAAGAA
GGTGAAAAAG CTCCAGGCGA GGACACACCT AGGATGCCTG GGAAAAGTGA AGGCTCCAGT
GACCTAGAAA ATACTCCAGG TCCTGATGCA GGGGCACAAG ATGAAGCGAA GGAACAAAGA
AATGGAACTA AATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016883165.1
CDS5..679
Translation

Target ORF information:

RefSeq Version XM_017027676.1
Organism Homo sapiens(Human)
Definition Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017027676.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGAATGAGT TTTTCTCCGT AGACGATAAT AATGAAGAAG AAGAGGATGT TGAAATGAAA 
GAAGATTCAG AAAGTAATGA CTTTGGTGGA CAAGAGGCAG TTGGAGGTTA TCTTAACAGA
GGATCAAGCC AATTCCTACA CTACAAGGGT AATCACTCCG CAATGAGTTC AGATGAGAAC
GGTCCAGAGG AGAAGCAAAG TGTGGAAGAA ATGGAAGAGC AGAGCCAAGA TGCAGATGGT
GTCAACACTG TCACTGTGCC CGGCCCTGCT TCAGAAGAGG CAGTTGAAGA CTGTAAAGAT
GAAGATTTTG CAAAGGATGA AAATATTACA AAAGGCGGTG AAGTGACAGA TCATTCTGTG
CGTGACCAAG ATCATCCCGA TGGACAAGAG AATGATTCAA CGAAGAATGA AATAAAAATT
GAAACAGAAT CGCAGAGCTC ATATATGGAA ACAGAAGAAC TTTCATCAAA CCAAGAAGAT
GCCGTGATTG TGGAGCAACC AGAAGTGATT CCATTAACAG AGGACCAAGA AGAAAAAGAA
GGTGAAAAAG CTCCAGGCGA GGACACACCT AGGATGCCTG GGAAAAGTGA AGGCTCCAGT
GACCTAGAAA ATACTCCAGG TCCTGATGCA GGGGCACAAG ATGAAGCGAA GGAACAAAGA
AATGGAACTA AATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu92925
Clone ID Related Accession (Same CDS sequence) XM_017027677.1
Accession Version XM_017027677.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1347bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product O-acetyl-ADP-ribose deacetylase MACROD2 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTACCCCA GCAACAAGAA GAAAAAGGTG TGGAGAGAGG AGAAAGAACG TTTATTGAAG 
ATGACCTTAG AAGAGAGACG CAAAGAATAC CTAAGAGACT ATATTCCCCT GAACAGCATT
CTATCATGGA AGGAGGAGAT GAAGGGCAAG GGCCAAAATG ATGAAGAAAA TACTCAGGAA
ACATCCCAGG TGAAGAAAAG TTTGACTGAA AAAGTTTCTC TCTATAGAGG TGACATCACA
TTGCTAGAGG TAGATGCTAT AGTCAATGCC GCAAATGCCA GTCTTCTTGG AGGAGGAGGT
GTGGATGGCT GTATTCATAG AGCAGCCGGC CCCTGTTTGC TAGCTGAATG TCGTAACCTG
AATGGCTGTG ATACTGGACA TGCAAAAATC ACATGTGGCT ATGACCTTCC TGCAAAATAT
GTCATCCATA CTGTAGGGCC AATAGCCAGG GGCCATATTA ATGGTTCCCA CAAGGAAGAC
CTTGCAAATT GCTATAAATC ATCTCTGAAG CTCGTGAAAG AAAATAACAT CCGATCAGTT
GCATTTCCCT GCATCTCAAC AGGCATTTAT GGCTTTCCCA ACGAGCCTGC TGCAGTCATT
GCCCTCAACA CCATTAAGGA ATGGCTTGCC AAGAATCACC ATGAGGTGGA TCGGATCATT
TTCTGTGTCT TCTTAGAAGT TGACTTCAAA ATCTACAAAA AGAAAATGAA TGAGTTTTTC
TCCGTAGACG ATAATAATGA AGAAGAAGAG GATGTTGAAA TGAAAGAAGA TTCAGATGAG
AACGGTCCAG AGGAGAAGCA AAGTGTGGAA GAAATGGAAG AGCAGAGCCA AGATGCAGAT
GGTGTCAACA CTGTCACTGT GCCCGGCCCT GCTTCAGAAG AGGCAGTTGA AGACTGTAAA
GATGAAGATT TTGCAAAGGA TGAAAATATT ACAAAAGGCG GTGAAGTGAC AGATCATTCT
GTGCGTGACC AAGATCATCC CGATGGACAA GAGAATGATT CAACGAAGAA TGAAATAAAA
ATTGAAACAG AATCGCAGAG CTCATATATG GAAACAGAAG AACTTTCATC AAACCAAGAA
GATGCCGTGA TTGTGGAGCA ACCAGAAGTG ATTCCATTAA CAGAGGACCA AGAAGAAAAA
GAAGGTGAAA AAGCTCCAGG CGAGGACACA CCTAGGATGC CTGGGAAAAG TGAAGGCTCC
AGTGACCTAG AAAATACTCC AGGTCCTGAT GTTGAAATGA ATAGTCAGGT TGACAAGGTA
AATGACCCAA CAGAGAGTCA ACAAGAAGAT CAACTAATAG CAGGGGCACA AGATGAAGCG
AAGGAACAAA GAAATGGAAC TAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016883166.1
CDS289..1635
Misc Feature(1)493..1005
Misc Feature(2)499..999
Misc Feature(3)order(520..525,562..564,583..585,589..594,844..846,850..858)
Misc Feature(4)order(553..555,562..564,580..582,592..594,715..717)
Translation

Target ORF information:

RefSeq Version XM_017027677.1
Organism Homo sapiens(Human)
Definition Homo sapiens MACRO domain containing 2 (MACROD2), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017027677.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTACCCCA GCAACAAGAA GAAAAAGGTG TGGAGAGAGG AGAAAGAACG TTTATTGAAG 
ATGACCTTAG AAGAGAGACG CAAAGAATAC CTAAGAGACT ATATTCCCCT GAACAGCATT
CTATCATGGA AGGAGGAGAT GAAGGGCAAG GGCCAAAATG ATGAAGAAAA TACTCAGGAA
ACATCCCAGG TGAAGAAAAG TTTGACTGAA AAAGTTTCTC TCTATAGAGG TGACATCACA
TTGCTAGAGG TAGATGCTAT AGTCAATGCC GCAAATGCCA GTCTTCTTGG AGGAGGAGGT
GTGGATGGCT GTATTCATAG AGCAGCCGGC CCCTGTTTGC TAGCTGAATG TCGTAACCTG
AATGGCTGTG ATACTGGACA TGCAAAAATC ACATGTGGCT ATGACCTTCC TGCAAAATAT
GTCATCCATA CTGTAGGGCC AATAGCCAGG GGCCATATTA ATGGTTCCCA CAAGGAAGAC
CTTGCAAATT GCTATAAATC ATCTCTGAAG CTCGTGAAAG AAAATAACAT CCGATCAGTT
GCATTTCCCT GCATCTCAAC AGGCATTTAT GGCTTTCCCA ACGAGCCTGC TGCAGTCATT
GCCCTCAACA CCATTAAGGA ATGGCTTGCC AAGAATCACC ATGAGGTGGA TCGGATCATT
TTCTGTGTCT TCTTAGAAGT TGACTTCAAA ATCTACAAAA AGAAAATGAA TGAGTTTTTC
TCCGTAGACG ATAATAATGA AGAAGAAGAG GATGTTGAAA TGAAAGAAGA TTCAGATGAG
AACGGTCCAG AGGAGAAGCA AAGTGTGGAA GAAATGGAAG AGCAGAGCCA AGATGCAGAT
GGTGTCAACA CTGTCACTGT GCCCGGCCCT GCTTCAGAAG AGGCAGTTGA AGACTGTAAA
GATGAAGATT TTGCAAAGGA TGAAAATATT ACAAAAGGCG GTGAAGTGAC AGATCATTCT
GTGCGTGACC AAGATCATCC CGATGGACAA GAGAATGATT CAACGAAGAA TGAAATAAAA
ATTGAAACAG AATCGCAGAG CTCATATATG GAAACAGAAG AACTTTCATC AAACCAAGAA
GATGCCGTGA TTGTGGAGCA ACCAGAAGTG ATTCCATTAA CAGAGGACCA AGAAGAAAAA
GAAGGTGAAA AAGCTCCAGG CGAGGACACA CCTAGGATGC CTGGGAAAAG TGAAGGCTCC
AGTGACCTAG AAAATACTCC AGGTCCTGAT GTTGAAATGA ATAGTCAGGT TGACAAGGTA
AATGACCCAA CAGAGAGTCA ACAAGAAGAT CAACTAATAG CAGGGGCACA AGATGAAGCG
AAGGAACAAA GAAATGGAAC TAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.
Proceedings of the National Academy of Sciences of the United States of America111(49)17606-11(2014 Dec)
Mohseni M,Cidado J,Croessmann S,Cravero K,Cimino-Mathews A,Wong HY,Scharpf R,Zabransky DJ,Abukhdeir AM,Garay JP,Wang GM,Beaver JA,Cochran RL,Blair BG,Rosen DM,Erlanger B,Argani P,Hurley PJ,Lauring J,Park BH


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Jones RM,Cadby G,Blangero J,Abraham LJ,Whitehouse AJO,Moses EK


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Wade TD,Gordon S,Medland S,Bulik CM,Heath AC,Montgomery GW,Martin NG


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Genome-wide association study of antiphospholipid antibodies.
Autoimmune diseases2013761046(2013)
Kamboh MI,Wang X,Kao AH,Barmada MM,Clarke A,Ramsey-Goldman R,Manzi S,Demirci FY


 
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