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ACSM6 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol ACSM6
Entrez Gene ID 142827
Full Name acyl-CoA synthetase medium chain family member 6
Synonyms C10orf129,bA310E22.3
General protein information
Preferred Names

acyl-CoA synthetase medium chain family member 6

Names

acyl-coenzyme A synthetase ACSM6, mitochondrial
AMP-binding enzyme

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

10

10q23.33


mRNA and Protein(s)

mRNA Protein Name
NM_207321.2 NP_997204.2 acyl-coenzyme A synthetase ACSM6, mitochondrial precursor



Homo sapiens (human) C10orf129 NP_997204.2
Pan troglodytes (chimpanzee) C10H10orf129 XP_001144196.2


Related articles in PubMed

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ
Nature504(7479)291-5(2013 Dec)

An integrated clinico-metabolomic model improves prediction of death in sepsis.
Langley RJ, Tsalik EL, van Velkinburgh JC, Glickman SW, Rice BJ, Wang C, Chen B, Carin L, Suarez A, Mohney RP, Freeman DH, Wang M, You J, Wulff J, Thompson JW, Moseley MA, Reisinger S, Edmonds BT, Grinnell B, Nelson DR, Dinwiddie DL, Miller NA, Saunders CJ, Soden SS, Rogers AJ, Gazourian L, Fredenburgh LE, Massaro AF, Baron RM, Choi AM, Corey GR, Ginsburg GS, Cairns CB, Otero RM, Fowler VG Jr, Rivers EP, Woods CW, Kingsmore SF
Science translational medicine5(195)195ra95(2013 Jul)

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A
American journal of human genetics78(1)78-88(2006 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The following ACSM6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACSM6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu27790 NM_207321.2
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Homo sapiens acyl-CoA synthetase medium-chain family member 6 (ACSM6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu27790
Clone ID Related Accession (Same CDS sequence) NM_207321.2
Accession Version NM_207321.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1443bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-12-24
Organism Homo sapiens(Human)
Product acyl-coenzyme A synthetase ACSM6, mitochondrial precursor
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK126134.1, BC104211.2 and BC063654.1. On Aug 7, 2008 this sequence version replaced NM_207321.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2142586 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGCTAGGCC GATTTCAACC CTTCTCCTTG GTCCGGAGTT TCAGACTGGG ATTTGAAGCC 
TGCTGCTATC CAAACCAAAA ATGTGCTACT CAGACCATCA GACCCCCTGA CTCCAGGTGC
CTAGTCCAAG CAGTTTCTCA GAACTTTAAT TTTGCAAAGG ATGTGTTGGA TCAGTGGTCC
CAGCTGGAAA AGGACGGACT CAGAGGGCCT TACCCCGCCC TCTGGAAGGT TAGTGCCAAA
GGAGAAGAGG ACAAATGGAG CTTTGAAAGG ATGACTCAAC TCTCCAAGAA GGCCGCCAGC
ATCCTCTCAG ACACCTGTGC CCTTAGCCAT GGAGACCGGC TGATGATAAT CTTGCCCCCA
ACACCTGAAG CCTACTGGAT CTGCCTGGCC TGTGTGCGCT TGGGAATCAC CTTTGTGCCT
GGGAGCCCCC AGCTGACTGC CAAGAAAATT CGCTATCAAT TACGCATGTC TAAGGCCCAG
TGCATTGTGG CTAATGAAGC TATGGCCCCA GTTGTAAACT CTGCCGTGTC CGACTGCCCC
ACCTTGAAAA CCAAGCTCCT GGTGTCAGAT AAGAGCTATG ATGGGTGGTT GGATTTCAAG
AAGTTGATTC AAGTTGCCCC TCCAAAGCAG ACCTACATGA GGACCAAAAG CCAAGATCCA
ATGGCCATAT TCTTCACCAA GGGTACAACA GGAGCTCCCA AAATGGTCGA GTATTCCCAG
TATGGTTTGG GAATGGGATT CAGCCAGGCT TCCAGACGGT GGATGGATCT CCAGCCAACA
GATGTCTTGT GGAGTCTGGG TGATGCCTTT GGTGGATCTT TATCCCTGAG CGCTGTCTTG
GGAACTTGGT TCCAAGGAGC CTGTGTGTTT CTGTGTCACA TGCCAACCTT CTGCCCTGAG
ACTGTTCTAA ATGTCCTGTC CAGATTTCCC ATCACCACTC TATCTGCAAA TCCAGAGATG
TACCAGGAAC TGCTTCAGCA CAAGTGTTTC ACCAGCTACA GATTCAAGAG TCTGAAGCAG
TGTGTGGCTG CAGGAGGACC CATCAGCCCT GGGGTGATTG AGGACTGGAA ACGCATCACT
AAGTTGGACA TCTATGAAGG CTATGGGCAG ACGGAAACTG GTCTACTCTG TGCCACTTCC
AAAACAATAA AATTGAAGCC AAGCTCTCTG GGGAAGCCAT TGCCACCTTA TATTGTCCAG
ATTGTGGATG AAAACTCAAA TCTCCTGCCT CCAGGGGAAG AAGGAAATAT TGCAATCCGC
ATAAAACTAA ACCAACCTGC TTCTCTGTAC TGTCCACACA TGGTGAGCTG GGAGGAATAT
GCTTCAGCAA GAGGCCACAT GCTTTACCTC ACAGGTGACA GAGGGATCAT GGATGAAGAC
GGCTACTTCT GGTGGTCTGG TAGAGTTGAT GATGTTGCCA ATGCATTGGG TCAGAGATTG
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_997204.2
CDS126..1568
Misc Feature(1)84..86
Misc Feature(2)258..1565
Misc Feature(3)351..1541
Misc Feature(4)order(792..794,801..818,822..827)
Misc Feature(5)order(801..803,924..929,1074..1076,1080..1085,1092..1094,1155..1160,1221..1238,1482..1484,1518..1520,1527..1529,1551..1562)
Misc Feature(6)order(801..803,1155..1160,1221..1238,1482..1484,1518..1520,1527..1529,1560..1562)
Misc Feature(7)order(924..926,1080..1085,1092..1094,1155..1157,1551..1559)
Exon (1)1..104
Exon (2)105..317
Exon (3)318..528
Exon (4)529..736
Exon (5)737..880
Exon (6)881..1037
Exon (7)1038..1120
Exon (8)1121..1244
Exon (9)1245..1325
Exon (10)1326..1427
Exon (11)1428..1713
Translation

Target ORF information:

RefSeq Version NM_207321.2
Organism Homo sapiens(Human)
Definition Homo sapiens acyl-CoA synthetase medium-chain family member 6 (ACSM6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_207321.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGCTAGGCC GATTTCAACC CTTCTCCTTG GTCCGGAGTT TCAGACTGGG ATTTGAAGCC 
TGCTGCTATC CAAACCAAAA ATGTGCTACT CAGACCATCA GACCCCCTGA CTCCAGGTGC
CTAGTCCAAG CAGTTTCTCA GAACTTTAAT TTTGCAAAGG ATGTGTTGGA TCAGTGGTCC
CAGCTGGAAA AGGACGGACT CAGAGGGCCT TACCCCGCCC TCTGGAAGGT TAGTGCCAAA
GGAGAAGAGG ACAAATGGAG CTTTGAAAGG ATGACTCAAC TCTCCAAGAA GGCCGCCAGC
ATCCTCTCAG ACACCTGTGC CCTTAGCCAT GGAGACCGGC TGATGATAAT CTTGCCCCCA
ACACCTGAAG CCTACTGGAT CTGCCTGGCC TGTGTGCGCT TGGGAATCAC CTTTGTGCCT
GGGAGCCCCC AGCTGACTGC CAAGAAAATT CGCTATCAAT TACGCATGTC TAAGGCCCAG
TGCATTGTGG CTAATGAAGC TATGGCCCCA GTTGTAAACT CTGCCGTGTC CGACTGCCCC
ACCTTGAAAA CCAAGCTCCT GGTGTCAGAT AAGAGCTATG ATGGGTGGTT GGATTTCAAG
AAGTTGATTC AAGTTGCCCC TCCAAAGCAG ACCTACATGA GGACCAAAAG CCAAGATCCA
ATGGCCATAT TCTTCACCAA GGGTACAACA GGAGCTCCCA AAATGGTCGA GTATTCCCAG
TATGGTTTGG GAATGGGATT CAGCCAGGCT TCCAGACGGT GGATGGATCT CCAGCCAACA
GATGTCTTGT GGAGTCTGGG TGATGCCTTT GGTGGATCTT TATCCCTGAG CGCTGTCTTG
GGAACTTGGT TCCAAGGAGC CTGTGTGTTT CTGTGTCACA TGCCAACCTT CTGCCCTGAG
ACTGTTCTAA ATGTCCTGTC CAGATTTCCC ATCACCACTC TATCTGCAAA TCCAGAGATG
TACCAGGAAC TGCTTCAGCA CAAGTGTTTC ACCAGCTACA GATTCAAGAG TCTGAAGCAG
TGTGTGGCTG CAGGAGGACC CATCAGCCCT GGGGTGATTG AGGACTGGAA ACGCATCACT
AAGTTGGACA TCTATGAAGG CTATGGGCAG ACGGAAACTG GTCTACTCTG TGCCACTTCC
AAAACAATAA AATTGAAGCC AAGCTCTCTG GGGAAGCCAT TGCCACCTTA TATTGTCCAG
ATTGTGGATG AAAACTCAAA TCTCCTGCCT CCAGGGGAAG AAGGAAATAT TGCAATCCGC
ATAAAACTAA ACCAACCTGC TTCTCTGTAC TGTCCACACA TGGTGAGCTG GGAGGAATAT
GCTTCAGCAA GAGGCCACAT GCTTTACCTC ACAGGTGACA GAGGGATCAT GGATGAAGAC
GGCTACTTCT GGTGGTCTGG TAGAGTTGAT GATGTTGCCA ATGCATTGGG TCAGAGATTG
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ


book

An integrated clinico-metabolomic model improves prediction of death in sepsis.
Science translational medicine5(195)195ra95(2013 Jul)
Langley RJ,Tsalik EL,van Velkinburgh JC,Glickman SW,Rice BJ,Wang C,Chen B,Carin L,Suarez A,Mohney RP,Freeman DH,Wang M,You J,Wulff J,Thompson JW,Moseley MA,Reisinger S,Edmonds BT,Grinnell B,Nelson DR,Dinwiddie DL,Miller NA,Saunders CJ,Soden SS,Rogers AJ,Gazourian L,Fredenburgh LE,Massaro AF,Baron RM,Choi AM,Corey GR,Ginsburg GS,Cairns CB,Otero RM,Fowler VG Jr,Rivers EP,Woods CW,Kingsmore SF


book

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
American journal of human genetics78(1)78-88(2006 Jan)
Grupe A,Li Y,Rowland C,Nowotny P,Hinrichs AL,Smemo S,Kauwe JS,Maxwell TJ,Cherny S,Doil L,Tacey K,van Luchene R,Myers A,Wavrant-De Vrièze F,Kaleem M,Hollingworth P,Jehu L,Foy C,Archer N,Hamilton G,Holmans P,Morris CM,Catanese J,Sninsky J,White TJ,Powell J,Hardy J,O'Donovan M,Lovestone S,Jones L,Morris JC,Thal L,Owen M,Williams J,Goate A


 
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