Gene Symbol | CSNK1G2 |
Entrez Gene ID | 1455 |
Full Name | casein kinase 1 gamma 2 |
Synonyms | CK1g2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » CSNK1G2 cDNA ORF clone
Gene Symbol | CSNK1G2 |
Entrez Gene ID | 1455 |
Full Name | casein kinase 1 gamma 2 |
Synonyms | CK1g2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001319.7 | NP_001310.3 | casein kinase I isoform gamma-2 |
XM_017026297.1 | XP_016881786.1 | casein kinase I isoform X1 |
XM_017026298.1 | XP_016881787.1 | casein kinase I isoform X4 |
NM_001319.6 | NP_001310.3 | casein kinase I isoform gamma-2 |
XM_005259500.1 | XP_005259557.1 | casein kinase I isoform X2 |
XM_005259498.1 | XP_005259555.1 | casein kinase I isoform X1 |
XM_005259499.3 | XP_005259556.1 | casein kinase I isoform X1 |
XM_005259501.2 | XP_005259558.1 | casein kinase I isoform X3 |
Homo sapiens (human) | CSNK1G2 | NP_001310.3 |
Caenorhabditis elegans (roundworm) | csnk-1 | NP_492694.1 |
LOC709484 | XP_002808209.1 | |
Rattus norvegicus (Norway rat) | Csnk1g2 | NP_001029042.1 |
Canis lupus familiaris (dog) | CSNK1G2 | XP_005633168.1 |
Bos taurus (cattle) | CSNK1G2 | NP_001094526.1 |
Danio rerio (zebrafish) | csnk1g2a | NP_001019550.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08097 | XP_003715052.1 |
Neurospora crassa | NCU04005 | XP_957620.1 |
Mus musculus (house mouse) | Csnk1g2 | NP_001153063.1 |
Kluyveromyces lactis | KLLA0D11044g | XP_453554.1 |
Eremothecium gossypii | AGOS_AFR040W | NP_985587.1 |
Schizosaccharomyces pombe (fission yeast) | cki1 | NP_596698.1 |
Pan troglodytes (chimpanzee) | CSNK1G2 | XP_512246.2 |
Gallus gallus (chicken) | LOC100857862 | XP_003642911.2 |
Saccharomyces cerevisiae (baker's yeast) | YCK2 | NP_014245.1 |
Saccharomyces cerevisiae (baker's yeast) | YCK1 | NP_012003.1 |
Schizosaccharomyces pombe (fission yeast) | cki2 | NP_595380.1 |
MicroRNA-155 regulates casein kinase 1 gamma 2: a potential pathogenetic role in chronic lymphocytic leukemia.
Zhang T, Davidson-Moncada JK, Mukherjee P, Furman RR, Bhavsar E, Chen Z, Hakimpour P, Papavasiliou N, Tam W
Blood cancer journal7(9)e606(2017 Sep)
Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)
Phosphorylation of LRRK2 by casein kinase 1? regulates trans-Golgi clustering via differential interaction with ARHGEF7.
Chia R, Haddock S, Beilina A, Rudenko IN, Mamais A, Kaganovich A, Li Y, Kumaran R, Nalls MA, Cookson MR
Nature communications55827(2014 Dec)
Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results indicate that CKIgamma2 hyperphosphorylates the serine-repeat motif of CERT, thereby inactivating CERT and down-regulating the synthesis of sphingomyelin.
Title: Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin.
Ligand-dependent ubiquitination of Smad3 is regulated by CK1g2, an inhibitor of TGF-beta signaling.
Title: Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling.
CK1epsilon and CK1gamma2 were found to bind to Per1 and to promote its degradation
Title: SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein.
Observational study of gene-disease association. (HuGE Navigator)
Title: Polymorphisms of casein kinase I gamma 2 gene associated with simple febrile seizures in Chinese Han population.
Data indicate that SNPs rs740423, rs2277737, rs1059684 of CSNK1G2 gene may contribute to familial febrile convulsions in children.
Title: [Five single nucleotide polymorphisms of casein kinase I gamma 2 gene in children with familial febrile convulsions].
The following CSNK1G2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSNK1G2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu02867 | |
Clone ID Related Accession (Same CDS sequence) | NM_001319.7 , NM_001319.6 | |
Accession Version | NM_001319.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-09 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform gamma-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC012615.4 and AC005306.2. On Nov 22, 2018 this sequence version replaced NM_001319.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.217532.1, SRR1163658.269787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000255641.13/ ENSP00000255641.7 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001310.3 |
CDS | 513..1760 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001319.7 |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu02867 | |
Clone ID Related Accession (Same CDS sequence) | NM_001319.7 , NM_001319.6 | |
Accession Version | NM_001319.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform gamma-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR994929.1, BC018693.2, BC020972.1 and CA423327.1. On Jul 25, 2007 this sequence version replaced NM_001319.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.269787.1, BC018693.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001310.3 |
CDS | 524..1771 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001319.6 |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu51435 | |
Clone ID Related Accession (Same CDS sequence) | XM_005259500.1 | |
Accession Version | XM_005259500.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1323bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005259557.1 |
CDS | 536..1858 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005259500.1 |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu51436 | |
Clone ID Related Accession (Same CDS sequence) | XM_005259501.2 | |
Accession Version | XM_005259501.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005259501.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACCGGT GGATGGTAGC TGTGAGGATG GACCGTGTGG CAGGAAAGAA TCTCTATACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005259558.1 |
CDS | 1054..2232 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005259501.2 |
1 | ATGGACCGGT GGATGGTAGC TGTGAGGATG GACCGTGTGG CAGGAAAGAA TCTCTATACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu88218 | |
Clone ID Related Accession (Same CDS sequence) | XM_017026298.1 | |
Accession Version | XM_017026298.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACCGGT GGATGGTAGC TGTGAGGATG GACCGTGTGG CAGGAAAGAA TCTCTATACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016881787.1 |
CDS | 1054..2157 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017026298.1 |
1 | ATGGACCGGT GGATGGTAGC TGTGAGGATG GACCGTGTGG CAGGAAAGAA TCTCTATACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu51434 | |
Clone ID Related Accession (Same CDS sequence) | XM_017026297.1 , XM_005259498.1 , XM_005259499.3 | |
Accession Version | XM_017026297.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016881786.1 |
CDS | 410..1747 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017026297.1 |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu51434 | |
Clone ID Related Accession (Same CDS sequence) | XM_017026297.1 , XM_005259498.1 , XM_005259499.3 | |
Accession Version | XM_005259498.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005259555.1 |
CDS | 536..1873 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005259498.1 |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu51434 | |
Clone ID Related Accession (Same CDS sequence) | XM_017026297.1 , XM_005259498.1 , XM_005259499.3 | |
Accession Version | XM_005259499.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | casein kinase I isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005259499.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005259556.1 |
CDS | 343..1680 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005259499.3 |
1 | ATGGATTTTG ACAAGAAAGG AGGGAAAGGG GAGACGGAGG AGGGCCGGAG AATGTCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
MicroRNA-155 regulates casein kinase 1 gamma 2: a potential pathogenetic role in chronic lymphocytic leukemia. |
Architecture of the human interactome defines protein communities and disease networks. |
Phosphorylation of LRRK2 by casein kinase 1? regulates trans-Golgi clustering via differential interaction with ARHGEF7. |
Defining the membrane proteome of NK cells. |