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CCDC80 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol CCDC80
Entrez Gene ID 151887
Full Name coiled-coil domain containing 80
Synonyms DRO1,SSG1,URB,okuribin
General protein information
Preferred Names

coiled-coil domain containing 80

Names

coiled-coil domain-containing protein 80
down-regulated by oncogenes protein 1
nuclear envelope protein okuribin
steroid sensitive gene 1
up-regulated in BRS-3 deficient mouse homolog
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

3

3q13.2
Disorder MIM:

608298


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_199512.2 NP_955806.1 coiled-coil domain-containing protein 80 precursor
NM_199511.3 NP_955805.1 coiled-coil domain-containing protein 80 precursor
NM_199512.3 NP_955806.1 coiled-coil domain-containing protein 80 precursor
NM_199511.2 NP_955805.1 coiled-coil domain-containing protein 80 precursor

Pathways from BioSystems


Homologies


Homo sapiens (human) CCDC80 NP_955805.1
Mus musculus (house mouse) Ccdc80 NP_080715.2
Danio rerio (zebrafish) ccdc80 NP_001007199.1
Canis lupus familiaris (dog) CCDC80 XP_005639700.1
Rattus norvegicus (Norway rat) Ccdc80 NP_071988.2
Pan troglodytes (chimpanzee) CCDC80 XP_001156251.2
CCDC80 XP_002802691.1
Bos taurus (cattle) CCDC80 NP_001092452.1
Gallus gallus (chicken) CCDC80 NP_989762.1

Gene Ontology


Bibliography

Related articles in PubMed

Adipose tissue and serum CCDC80 in obesity and its association with related metabolic disease.
Osorio-Conles O, Guitart M, Moreno-Navarrete JM, Escot? X, Duran X, Fernandez-Real JM, Gomez-Foix AM, Fern?ndez-Veledo S, Vendrell J
Molecular medicine (Cambridge, Mass.)23(2017 Aug)

Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.
Walczak EM, Kuick R, Finco I, Bohin N, Hrycaj SM, Wellik DM, Hammer GD
Molecular endocrinology (Baltimore, Md.)28(9)1471-86(2014 Sep)

Steroid-sensitive gene 1 is a novel cyclic GMP-dependent protein kinase I substrate in vascular smooth muscle cells.
Wang GR, Surks HK, Tang KM, Zhu Y, Mendelsohn ME, Blanton RM
The Journal of biological chemistry288(34)24972-83(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ccdc80 is a novel betacat-regulated gene in adrenocortical cells
Title: Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.

activation of PKGI with cGMP regulated SSG1 intracellular distribution.
Title: Steroid-sensitive gene 1 is a novel cyclic GMP-dependent protein kinase I substrate in vascular smooth muscle cells.

Data suggest that CCDC80 expression is down-regulated in many thyroid carcinomas; loss of heterozygosity partially accounts for CCDC80 down-regulation in thyroid carcinoma; CCDC80 expression positively regulates expression of E-cadherin.
Title: Tumor suppressor role of the CL2/DRO1/CCDC80 gene in thyroid carcinogenesis.

Results reveal DRO1 as an AIB1-targeted tumor suppressor, providing a novel mechanism for AIB1-dependent inhibition of apoptosis.
Title: Transcriptional repression of the tumor suppressor DRO1 by AIB1.

In conclusion, the expression pattern of URB suggests its role in obesity and the results suggest that URB is secreted, at least in part, from adipocytes.
Title: URB is abundantly expressed in adipose tissue and dysregulated in obesity.

The following CCDC80 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCDC80 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu02830 NM_199511.3
Latest version!		 Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu02830 NM_199512.3
Latest version!		 Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
View Old Accession Versions >>
OHu02830 NM_199512.2 Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu02830 NM_199511.2 Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu02830
Clone ID Related Accession (Same CDS sequence) NM_199512.2 , NM_199511.3 , NM_199512.3 , NM_199511.2
Accession Version NM_199512.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2853bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-23
Organism Homo sapiens(human)
Product coiled-coil domain-containing protein 80 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA573543.1, BC110842.1, BC116178.1 and CN360806.1. On Dec 11, 2013 this sequence version replaced NM_199512.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF506819.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_955806.1
CDS232..3084
Translation

Target ORF information:

RefSeq Version NM_199512.2
Organism Homo sapiens(human)
Definition Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_199512.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02830
Clone ID Related Accession (Same CDS sequence) NM_199512.2 , NM_199511.3 , NM_199512.3 , NM_199511.2
Accession Version NM_199511.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2853bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2020-01-04
Organism Homo sapiens(human)
Product coiled-coil domain-containing protein 80 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC048334.21. On or before Nov 30, 2019 this sequence version replaced NR_109779.1, NM_199511.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC116178.1, AY548106.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_955805.1
CDS829..3681
Translation

Target ORF information:

RefSeq Version NM_199511.3
Organism Homo sapiens(human)
Definition Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_199511.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02830
Clone ID Related Accession (Same CDS sequence) NM_199512.2 , NM_199511.3 , NM_199512.3 , NM_199511.2
Accession Version NM_199512.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2853bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2020-01-04
Organism Homo sapiens(human)
Product coiled-coil domain-containing protein 80 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC048334.21. On Nov 30, 2019 this sequence version replaced NM_199512.2. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF506819.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_955806.1
CDS232..3084
Translation

Target ORF information:

RefSeq Version NM_199512.3
Organism Homo sapiens(human)
Definition Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_199512.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02830
Clone ID Related Accession (Same CDS sequence) NM_199512.2 , NM_199511.3 , NM_199512.3 , NM_199511.2
Accession Version NM_199511.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2853bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-05-03
Organism Homo sapiens(human)
Product coiled-coil domain-containing protein 80 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA573543.1, BC110842.1, BC116178.1 and CN360806.1. On Dec 11, 2013 this sequence version replaced NM_199511.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC116178.1, AY548106.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_955805.1
CDS829..3681
Translation

Target ORF information:

RefSeq Version NM_199511.2
Organism Homo sapiens(human)
Definition Homo sapiens coiled-coil domain containing 80 (CCDC80), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_199511.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGACATGGA GAATGGGACC CCGTTTCACT ATGCTGTTGG CCATGTGGCT AGTGTGTGGA 
TCAGAACCCC ACCCCCATGC CACTATTAGA GGCAGCCACG GAGGACGGAA AGTGCCTTTG 
GTTTCTCCGG ACAGCAGTAG GCCAGCTCGG TTTCTGAGGC ACACTGGGAG GTCTCGCGGA 
ATTGAGAGAT CCACTCTGGA GGAACCAAAC CTTCAGCCTC TCCAGAGAAG GAGGAGTGTG 
CCCGTGTTGA GACTAGCTCG CCCAACAGAG CCGCCAGCCC GCTCGGACAT CAATGGGGCC 
GCCGTGAGAC CTGAGCAAAG ACCAGCAGCC AGGGGCTCTC CGCGTGAGAT GATCAGAGAT 
GAGGGGTCCT CAGCTCGGTC AAGAATGTTG CGTTTCCCTT CGGGGTCCAG CTCTCCCAAC 
ATCCTTGCCA GCTTTGCAGG GAAGAACAGA GTATGGGTCA TCTCAGCCCC TCATGCCTCG 
GAAGGCTACT ACCGCCTCAT GATGAGCCTG CTGAAGGACG ATGTGTACTG TGAGCTGGCG 
GAGAGGCACA TCCAACAGAT TGTGCTCTTC CACCAGGCAG GTGAGGAAGG AGGCAAGGTG 
AGAAGGATCA CCAGCGAGGG CCAGATCCTG GAGCAGCCCC TGGACCCTAG CCTCATCCCT 
AAGCTGATGA GCTTCCTGAA GCTGGAGAAG GGCAAGTTTG GCATGGTGCT GCTGAAGAAG 
ACGCTGCAGG TGGAGGAGCG CTATCCATAT CCCGTTAGGC TGGAAGCCAT GTACGAGGTC 
ATCGACCAAG GCCCCATCCG TAGGATCGAG AAGATCAGGC AGAAGGGCTT TGTCCAGAAA 
TGTAAGGCCT CTGGTGTAGA GGGCCAGGTG GTGGCGGAGG GGAATGACGG TGGAGGGGGA 
GCAGGAAGGC CAAGCCTGGG CAGCGAGAAG AAGAAAGAGG ACCCAAGGAG AGCACAAGTC 
CCACCAACCA GAGAGAGTCG GGTGAAGGTC CTGAGAAAAC TGGCCGCCAC TGCACCAGCT 
TTGCCCCAAC CTCCCTCAAC CCCCAGAGCC ACCACCCTTC CTCCTGCCCC AGCCACAACA 
GTGACTCGGT CCACGTCCCG GGCGGTAACA GTTGCTGCAA GACCTATGAC CACCACTGCC 
TTTCCCACCA CGCAGAGGCC CTGGACCCCC TCACCCTCCC ACAGGCCCCC TACAACCACT 
GAGGTGATCA CTGCCAGGAG ACCCTCAGTT TCAGAGAATC TTTACCCTCC ATCCCGGAAG 
GATCAGCACA GGGAGAGGCC ACAGACAACC AGGAGGCCCA GCAAGGCCAC CAGCTTGGAG 
AGCTTCACAA ATGCCCCTCC CACCACCATC TCAGAACCCA GCACAAGGGC TGCTGGCCCA 
GGCCGTTTCC GGGACAACCG CATGGACAGG CGGGAACATG GCCACCGAGA CCCAAATGTG 
GTGCCAGGTC CTCCCAAGCC AGCAAAGGAG AAACCTCCCA AAAAGAAGGC CCAGGACAAA 
ATTCTTAGTA ATGAGTATGA GGAGAAGTAT GACCTCAGCC GGCCTACTGC CTCTCAGCTG 
GAGGACGAGC TGCAGGTGGG GAATGTTCCC CTTAAAAAAG CAAAGGAGTC TAAAAAGCAT 
GAAAAGCTTG AGAAACCAGA GAAGGAGAAG AAAAAAAAGA TGAAGAATGA GAACGCAGAC 
AAGTTACTTA AGAGTGAAAA GCAAATGAAG AAGTCTGAGA AAAAGAGCAA GCAAGAGAAA 
GAGAAGAGCA AGAAGAAAAA AGGAGGTAAA ACAGAACAGG ATGGCTATCA GAAACCCACC 
AACAAACACT TCACGCAGAG TCCCAAGAAG TCAGTGGCCG ACCTGCTGGG GTCCTTTGAA 
GGCAAACGAA GACTCCTTCT GATCACTGCT CCCAAGGCTG AGAACAATAT GTATGTGCAA 
CAACGTGATG AATATCTGGA AAGTTTCTGC AAGATGGCTA CCAGGAAAAT CTCTGTGATC 
ACCATCTTCG GCCCTGTCAA CAACAGCACC ATGAAAATCG ACCACTTTCA GCTAGATAAT 
GAGAAGCCCA TGCGAGTGGT GGATGATGAA GACTTGGTAG ACCAGCGTCT CATCAGCGAG 
CTGAGGAAAG AGTACGGAAT GACCTACAAT GACTTCTTCA TGGTGCTAAC AGATGTGGAT 
CTGAGAGTCA AGCAATACTA TGAGGTACCA ATAACAATGA AGTCTGTGTT TGATCTGATC 
GATACTTTCC AGTCCCGAAT CAAAGATATG GAGAAGCAGA AGAAGGAGGG CATTGTTTGC 
AAAGAGGACA AAAAGCAGTC CCTGGAGAAC TTCCTATCCA GGTTCCGGTG GAGGAGGAGG 
TTGCTGGTGA TCTCTGCTCC TAACGATGAA GACTGGGCCT ATTCACAGCA GCTCTCTGCC 
CTCAGTGGTC AGGCGTGCAA TTTTGGTCTG CGCCACATAA CCATTCTGAA GCTTTTAGGC 
GTTGGAGAGG AAGTTGGGGG AGTGTTAGAA CTGTTCCCAA TTAATGGGAG CTCTGTTGTT 
GAGCGAGAAG ACGTACCAGC CCATTTGGTG AAAGACATTC GTAACTATTT TCAAGTGAGC 
CCGGAGTACT TCTCCATGCT TCTAGTCGGA AAAGACGGAA ATGTCAAATC CTGGTATCCT 
TCCCCAATGT GGTCCATGGT GATTGTGTAC GATTTAATTG ATTCGATGCA ACTTCGGAGA 
CAGGAAATGG CGATTCAGCA GTCACTGGGG ATGCGCTGCC CAGAAGATGA GTATGCAGGC 
TATGGTTACC ATAGTTACCA CCAAGGATAC CAGGATGGTT ACCAGGATGA CTACCGTCAT 
CATGAGAGTT ATCACCATGG ATACCCTTAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Adipose tissue and serum CCDC80 in obesity and its association with related metabolic disease.
Molecular medicine (Cambridge, Mass.)23(2017 Aug)
Osorio-Conles O,Guitart M,Moreno-Navarrete JM,Escot? X,Duran X,Fernandez-Real JM,Gomez-Foix AM,Fern?ndez-Veledo S,Vendrell J


book

Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.
Molecular endocrinology (Baltimore, Md.)28(9)1471-86(2014 Sep)
Walczak EM,Kuick R,Finco I,Bohin N,Hrycaj SM,Wellik DM,Hammer GD


book

Steroid-sensitive gene 1 is a novel cyclic GMP-dependent protein kinase I substrate in vascular smooth muscle cells.
The Journal of biological chemistry288(34)24972-83(2013 Aug)
Wang GR,Surks HK,Tang KM,Zhu Y,Mendelsohn ME,Blanton RM