Gene Symbol | SYNPO2 |
Entrez Gene ID | 171024 |
Full Name | synaptopodin 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » SYNPO2 cDNA ORF clone
gRNAs
Gene Symbol | SYNPO2 |
Entrez Gene ID | 171024 |
Full Name | synaptopodin 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001128933.2 | NP_001122405.1 | synaptopodin-2 isoform b |
NM_001286754.1 | NP_001273683.1 | synaptopodin-2 isoform d |
NM_001286755.1 | NP_001273684.1 | synaptopodin-2 isoform e |
NM_133477.2 | NP_597734.2 | synaptopodin-2 isoform a |
NM_001128933.3 | NP_001122405.1 | synaptopodin-2 isoform b |
NM_001286754.2 | NP_001273683.1 | synaptopodin-2 isoform d |
NM_001128934.3 | NP_001122406.1 | synaptopodin-2 isoform c |
NM_001128934.2 | NP_001122406.1 | synaptopodin-2 isoform c |
NM_133477.3 | NP_597734.2 | synaptopodin-2 isoform a |
Pan troglodytes (chimpanzee) | SYNPO2 | XP_001148597.1 |
SYNPO2 | XP_001098526.1 | |
Rattus norvegicus (Norway rat) | Synpo2 | NP_001178892.1 |
Canis lupus familiaris (dog) | SYNPO2 | XP_853728.2 |
Homo sapiens (human) | SYNPO2 | NP_597734.2 |
Bos taurus (cattle) | SYNPO2 | NP_001077220.1 |
Mus musculus (house mouse) | Synpo2 | NP_536699.2 |
Gallus gallus (chicken) | SYNPO2 | XP_426324.3 |
Xenopus tropicalis (tropical clawed frog) | synpo2 | XP_004911507.1 |
Synaptopodin-2 suppresses metastasis of triple-negative breast cancer via inhibition of YAP/TAZ activity.
Liu J, Ye L, Li Q, Wu X, Wang B, Ouyang Y, Yuan Z, Li J, Lin C
The Journal of pathology244(1)71-83(2018 Jan)
Association of a common variant of SYNPO2 gene with increased risk of serous epithelial ovarian cancer.
Ma L, Zhang W, Ding Z, Wu SG, Jin Y, Jiang N, Du H, Cai D, Miao L, Chen X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(2)1010428317691185(2017 Feb)
Myopodin methylation is a prognostic biomarker and predicts antiangiogenic response in advanced kidney cancer.
Pompas-Veganzones N, Sandonis V, Perez-Lanzac A, Beltran M, Beardo P, Ju?rez A, Vazquez F, Cozar JM, Alvarez-Ossorio JL, Sanchez-Carbayo M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(10)14301-14310(2016 Oct)
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.
Perisic Matic L, Rykaczewska U, Razuvaev A, Sabater-Lleal M, Lengquist M, Miller CL, Ericsson I, R?hl S, Kronqvist M, Aldi S, Magn? J, Paloschi V, Vesterlund M, Li Y, Jin H, Diez MG, Roy J, Baldassarre D, Veglia F, Humphries SE, de Faire U, Tremoli E, Odeberg J, Vukojevi? V, Lehti? J, Maegdefessel L, Ehrenborg E, Paulsson-Berne G, Hansson GK, Lindeman JH, Eriksson P, Quertermous T, Hamsten A, Hedin U
Arteriosclerosis, thrombosis, and vascular biology36(9)1947-61(2016 Sep)
Prognostic Significance of Promoter Hypermethylation and Diminished Gene Expression of SYNPO2 in Melanoma.
Gao L, van den Hurk K, Nsengimana J, Laye JP, van den Oord JJ, Beck S, Gruis NA, Zoutman WH, van Engeland M, Newton-Bishop JA, Winnepenninckx VJ, van Doorn R
The Journal of investigative dermatology135(9)2328-2331(2015 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These findings uncover a suppressive role of SYNPO2 in triple-negative breast cancer (TNBC) metastasis via inhibition of YAP/TAZ, and suggest that SYNPO2 might provide a potential prognosis marker and novel therapeutic strategy.
Title: Synaptopodin-2 suppresses metastasis of triple-negative breast cancer via inhibition of YAP/TAZ activity.
Results show that SYNPO2 gene plays an important role in the etiology of epithelial ovarian cancer, suggesting that this gene may be a potential genetic modifier for developing epithelial ovarian cancer.
Title: Association of a common variant of SYNPO2 gene with increased risk of serous epithelial ovarian cancer.
High Myopodin methylation is associated with metastasis in kidney cancer.
Title: Myopodin methylation is a prognostic biomarker and predicts antiangiogenic response in advanced kidney cancer.
LMOD1, SYNPO2, PDLIM7, PLN, and SYNM down-regulation reflect the altered phenotype of smooth muscle cells in vascular disease and could be early sensitive markers of SMC dedifferentiation.
Title: Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.
Promoter hypermethylation and down regulation of SYNPO2 has significance in the prognosis of melanoma patients.
Title: Prognostic Significance of Promoter Hypermethylation and Diminished Gene Expression of SYNPO2 in Melanoma.
The following SYNPO2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SYNPO2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
Online Only Promotion
Up to 50% OFF! Starting
from $49/clone
CloneID | OHu26233![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_133477.2 , NM_133477.3 | |
Accession Version | NM_133477.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3786bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL833547.1, BC150629.1, AL833294.1 and AC107048.3. On Jun 27, 2008 this sequence version replaced NM_133477.1. Transcript Variant: This variant (1) encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL833547.1, BC150629.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_597734.2 |
CDS | 197..3982 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu26233![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_133477.2 , NM_133477.3 | |
Accession Version | NM_133477.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3786bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-07 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL833547.1, BC150629.1, AL833294.1 and AC107048.3. On Nov 23, 2018 this sequence version replaced NM_133477.2. Transcript Variant: This variant (1) encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR936673.1, BC150629.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000307142.9/ ENSP00000306015.4 RefSeq Select criteria :: based on manual assertion, conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_597734.2 |
CDS | 184..3969 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu27682 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286755.1 | |
Accession Version | NM_001286755.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-07 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform e | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL833547.1, CR936673.1, CB998857.1 and AV734727.1. Transcript Variant: This variant (5) lacks two consecutive exons in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (e) has a shorter and distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.205887.1, SRR1803611.215612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273684.1 |
CDS | 197..568 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu09842 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286754.1 , NM_001286754.2 | |
Accession Version | NM_001286754.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from KF147165.1, EU481975.1, AL833294.1, CR936673.1, CB998857.1 and AV734727.1. Transcript Variant: This variant (4) contains an alternate 5'-terminal exon, compared to variant 1. The encoded isoform (d) has a shorter and distinct N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KF147165.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTTACAC AGATTCGAAA TCAGAGCAAA GCCTCTGGGT CTGGGCTCTG TGAGGGAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273683.1 |
CDS | 242..3934 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTTACAC AGATTCGAAA TCAGAGCAAA GCCTCTGGGT CTGGGCTCTG TGAGGGAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu09842 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286754.1 , NM_001286754.2 | |
Accession Version | NM_001286754.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-08 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC108030.4, KF147165.1, EU481975.1, AL833294.1, CR936673.1, CB998857.1 and AV734727.1. On May 31, 2019 this sequence version replaced NM_001286754.1. Transcript Variant: This variant (4) contains an alternate 5'-terminal exon, compared to variant 1. The encoded isoform (d) has a shorter and distinct N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KF147165.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTTACAC AGATTCGAAA TCAGAGCAAA GCCTCTGGGT CTGGGCTCTG TGAGGGAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273683.1 |
CDS | 249..3941 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTTACAC AGATTCGAAA TCAGAGCAAA GCCTCTGGGT CTGGGCTCTG TGAGGGAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu10201 | |
Clone ID Related Accession (Same CDS sequence) | NM_001128933.2 , NM_001128933.3 | |
Accession Version | NM_001128933.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3282bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-23 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL833547.1, AL833294.1 and AC096745.2. On Nov 15, 2013 this sequence version replaced NM_001128933.1. Transcript Variant: This variant (2) lacks part of the 3' coding region, and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a shorter and distinct C-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL833294.1, SRR1660805.202613.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001122405.1 |
CDS | 197..3478 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu10201 | |
Clone ID Related Accession (Same CDS sequence) | NM_001128933.2 , NM_001128933.3 | |
Accession Version | NM_001128933.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3282bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-08 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL833547.1, AL833294.1 and AC096745.2. On May 31, 2019 this sequence version replaced NM_001128933.2. Transcript Variant: This variant (2) lacks part of the 3' coding region, and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a shorter and distinct C-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.110317.1, AL833294.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001122405.1 |
CDS | 184..3465 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu27591 | |
Clone ID Related Accession (Same CDS sequence) | NM_001128934.3 , NM_001128934.2 | |
Accession Version | NM_001128934.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3330bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-08 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL833547.1, AL833294.1, EU481975.1 and AK000774.1. On May 31, 2019 this sequence version replaced NM_001128934.2. Transcript Variant: This variant (3) contains an alternate 3'-terminal exon, compared to variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) has a shorter and distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU481975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001122406.1 |
CDS | 184..3513 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu27591 | |
Clone ID Related Accession (Same CDS sequence) | NM_001128934.3 , NM_001128934.2 | |
Accession Version | NM_001128934.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3330bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-23 | |
Organism | Homo sapiens(human) | |
Product | synaptopodin-2 isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL833547.1, AL833294.1, EU481975.1, AK000774.1 and AA043349.1. On Nov 15, 2013 this sequence version replaced NM_001128934.1. Transcript Variant: This variant (3) contains an alternate 3'-terminal exon, compared to variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) has a shorter and distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU481975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001122406.1 |
CDS | 197..3526 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCACAG GGGATTTTAT CTGCATTTCC ATGACTGGAG GGGCGCCCTG GGGGTTCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Synaptopodin-2 suppresses metastasis of triple-negative breast cancer via inhibition of YAP/TAZ activity. |
Association of a common variant of SYNPO2 gene with increased risk of serous epithelial ovarian cancer. |
Myopodin methylation is a prognostic biomarker and predicts antiangiogenic response in advanced kidney cancer. |
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM. |
Prognostic Significance of Promoter Hypermethylation and Diminished Gene Expression of SYNPO2 in Melanoma. |