CENPV cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CENPV
Entrez Gene ID	201161
Full Name	centromere protein V
Synonyms	3110013H01Rik,CENP-V,PRR6,p30
General protein information	Preferred Names centromere protein V Names centromere protein V nuclear protein p30 proline rich 6 proline-rich protein 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p11.2
Disorder MIM:	608139

mRNA and Protein(s)

mRNA	Protein	Name
NM_181716.3	NP_859067.2	centromere protein V
NM_181716.2	NP_859067.2	centromere protein V

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CENPV	XP_002695907.3
Gallus gallus (chicken)	CENPV	XP_415846.2
Xenopus tropicalis (tropical clawed frog)	cenpv	NP_001090779.1
Caenorhabditis elegans (roundworm)	CELE_F25B4.8	NP_741540.1
Arabidopsis thaliana (thale cress)	AT5G16940	NP_001154714.1
Homo sapiens (human)	CENPV	NP_859067.2
Pan troglodytes (chimpanzee)	CENPV	XP_511783.2
Rattus norvegicus (Norway rat)	Cenpv	XP_577104.3
Danio rerio (zebrafish)	cenpv	XP_002662101.1
Canis lupus familiaris (dog)	CENPV	XP_005620385.1
Mus musculus (house mouse)	Cenpv	NP_082724.1
Oryza sativa (rice)	Os09g0397700	NP_001063106.1

Gene Ontology
Bibliography

Related articles in PubMed

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.
Ahmeti KB, Ajroud-Driss S, Al-Chalabi A, Andersen PM, Armstrong J, Birve A, Blauw HM, Brown RH, Bruijn L, Chen W, Chio A, Comeau MC, Cronin S, Diekstra FP, Soraya Gkazi A, Glass JD, Grab JD, Groen EJ, Haines JL, Hardiman O, Heller S, Huang J, Hung WY, , Jaworski JM, Jones A, Khan H, Landers JE, Langefeld CD, Leigh PN, Marion MC, McLaughlin RL, Meininger V, Melki J, Miller JW, Mora G, Pericak-Vance MA, Rampersaud E, Robberecht W, Russell LP, Salachas F, Saris CG, Shatunov A, Shaw CE, Siddique N, Siddique T, Smith BN, Sufit R, Topp S, Traynor BJ, Vance C, van Damme P, van den Berg LH, van Es MA, van Vught PW, Veldink JH, Yang Y, Zheng JG,
Neurobiology of aging34(1)357.e7-19(2013 Jan)

Identification of CENP-V as a novel microtubule-associating molecule that activates Src family kinases through SH3 domain interaction.
Honda Z, Suzuki T, Honda H
Genes to cells : devoted to molecular & cellular mechanisms14(12)1383-94(2009 Dec)

CENP-V is required for centromere organization, chromosome alignment and cytokinesis.
Tadeu AM, Ribeiro S, Johnston J, Goldberg I, Gerloff D, Earnshaw WC
The EMBO journal27(19)2510-22(2008 Oct)

Proteomic analysis of the mammalian nuclear pore complex.
Cronshaw JM, Krutchinsky AN, Zhang W, Chait BT, Matunis MJ
The Journal of cell biology158(5)915-27(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that CENP-V (nuclear protein p30) is required for centromere organization, chromosome alignment and cytokinesis in human cells
Title: CENP-V is required for centromere organization, chromosome alignment and cytokinesis.

The following CENPV gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CENPV cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07595	NM_181716.3 Latest version!	Homo sapiens centromere protein V (CENPV), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu07595	NM_181716.2	Homo sapiens centromere protein V (CENPV), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CENPV ( NM_181716.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_859067.2 Homo sapiens centromere protein V (CENPV), mRNA.

Price & Availability↑

CloneID	OHu07595
Clone ID Related Accession (Same CDS sequence)	NM_181716.3 , NM_181716.2
Accession Version	NM_181716.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 819bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	centromere protein V
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ052702.1, AF514992.1 and BU618545.1. On Nov 22, 2018 this sequence version replaced NM_181716.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.49141.1, BC052604.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000299736.5/ ENSP00000299736.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCGGCGAT CGAGGAGCTC TGCGGCCGCC AAGCTGCGCG GGCAGAAGCG GTCCGGGGCC 
TCCGCGGCCC CCGCGGCCTC CGCGGCCGCT GCCTTGGCAC CCAGCGCCAC CCGCACACGG 
CGCTCCGCTA GCCAGGCCGG GAGCAAGAGC CAGGCGGTGG AGAAGCCGCC GTCGGAGAAG 
CCGCGGCTGA GGCGCTCGTC GCCGCGGGCC CAGGAGGAGG GCCCGGGGGA GCCGCCGCCG 
CCTGAGCTGG CGTTGCTCCC GCCACCGCCG CCGCCGCCGC CGACTCCCGC GACCCCGACG 
TCCTCGGCGT CCAACCTGGA CCTGGGCGAG CAGCGGGAGC GCTGGGAGAC GTTCCAGAAG 
CGGCAGAAGC TTACCTCCGA GGGTGCCGCC AAGCTCCTGC TAGACACCTT TGAATACCAG 
GGCCTGGTGA AGCACACAGG AGGCTGCCAC TGTGGAGCAG TTCGTTTTGA AGTTTGGGCC 
TCAGCAGACT TGCATATATT TGACTGCAAT TGCAGCATTT GCAAGAAGAA GCAGAATAGA 
CACTTCATTG TTCCAGCTTC TCGCTTCAAG CTCCTGAAGG GAGCTGAGCA CATAACGACT 
TACACGTTCA ATACTCACAA AGCCCAGCAT ACCTTCTGTA AGAGATGTGG CGTTCAGAGC 
TTCTATACTC CACGATCAAA CCCCGGAGGC TTCGGAATTG CCCCCCACTG CCTGGATGAG 
GGCACTGTGC GGAGTATGGT CACTGAGGAA TTCAATGGCA GCGATTGGGA GAAGGCCATG 
AAAGAGCACA AGACCATCAA GAACATGTCT AAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_859067.2
CDS	34..852
Translation	MRRSRSSAAAKLRGQKRSGASAAPAASAAAALAPSATRTRRSASQAGSKSQAVEKPPSEKPRLRRSSPRAQEEGPGEPPPPELALLPPPPPPPPTPATPTSSASNLDLGEQRERWETFQKRQKLTSEGAAKLLLDTFEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNRHFIVPASRFKLLKGAEHITTYTFNTHKAQHTFCKRCGVQSFYTPRSNPGGFGIAPHCLDEGTVRSMVTEEFNGSDWEKAMKEHKTIKNMSKE

Target ORF information:

RefSeq Version	NM_181716.3
Organism	Homo sapiens(human)
Definition	Homo sapiens centromere protein V (CENPV), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181716.3

ORF Insert Sequence:

ATGCGGCGAT CGAGGAGCTC TGCGGCCGCC AAGCTGCGCG GGCAGAAGCG GTCCGGGGCC 
TCCGCGGCCC CCGCGGCCTC CGCGGCCGCT GCCTTGGCAC CCAGCGCCAC CCGCACACGG 
CGCTCCGCTA GCCAGGCCGG GAGCAAGAGC CAGGCGGTGG AGAAGCCGCC GTCGGAGAAG 
CCGCGGCTGA GGCGCTCGTC GCCGCGGGCC CAGGAGGAGG GCCCGGGGGA GCCGCCGCCG 
CCTGAGCTGG CGTTGCTCCC GCCACCGCCG CCGCCGCCGC CGACTCCCGC GACCCCGACG 
TCCTCGGCGT CCAACCTGGA CCTGGGCGAG CAGCGGGAGC GCTGGGAGAC GTTCCAGAAG 
CGGCAGAAGC TTACCTCCGA GGGTGCCGCC AAGCTCCTGC TAGACACCTT TGAATACCAG 
GGCCTGGTGA AGCACACAGG AGGCTGCCAC TGTGGAGCAG TTCGTTTTGA AGTTTGGGCC 
TCAGCAGACT TGCATATATT TGACTGCAAT TGCAGCATTT GCAAGAAGAA GCAGAATAGA 
CACTTCATTG TTCCAGCTTC TCGCTTCAAG CTCCTGAAGG GAGCTGAGCA CATAACGACT 
TACACGTTCA ATACTCACAA AGCCCAGCAT ACCTTCTGTA AGAGATGTGG CGTTCAGAGC 
TTCTATACTC CACGATCAAA CCCCGGAGGC TTCGGAATTG CCCCCCACTG CCTGGATGAG 
GGCACTGTGC GGAGTATGGT CACTGAGGAA TTCAATGGCA GCGATTGGGA GAAGGCCATG 
AAAGAGCACA AGACCATCAA GAACATGTCT AAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CENPV ( NM_181716.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_859067.2 Homo sapiens centromere protein V (CENPV), mRNA.

Price & Availability↑

CloneID	OHu07595
Clone ID Related Accession (Same CDS sequence)	NM_181716.3 , NM_181716.2
Accession Version	NM_181716.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 819bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	centromere protein V
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ052702.1, AF514992.1 and BU618545.1. On Nov 29, 2004 this sequence version replaced NM_181716.1. ##Evidence-Data-START## Transcript exon combination :: BC052604.1, SRR1163658.49141.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGCGAT CGAGGAGCTC TGCGGCCGCC AAGCTGCGCG GGCAGAAGCG GTCCGGGGCC 
TCCGCGGCCC CCGCGGCCTC CGCGGCCGCT GCCTTGGCAC CCAGCGCCAC CCGCACACGG 
CGCTCCGCTA GCCAGGCCGG GAGCAAGAGC CAGGCGGTGG AGAAGCCGCC GTCGGAGAAG 
CCGCGGCTGA GGCGCTCGTC GCCGCGGGCC CAGGAGGAGG GCCCGGGGGA GCCGCCGCCG 
CCTGAGCTGG CGTTGCTCCC GCCACCGCCG CCGCCGCCGC CGACTCCCGC GACCCCGACG 
TCCTCGGCGT CCAACCTGGA CCTGGGCGAG CAGCGGGAGC GCTGGGAGAC GTTCCAGAAG 
CGGCAGAAGC TTACCTCCGA GGGTGCCGCC AAGCTCCTGC TAGACACCTT TGAATACCAG 
GGCCTGGTGA AGCACACAGG AGGCTGCCAC TGTGGAGCAG TTCGTTTTGA AGTTTGGGCC 
TCAGCAGACT TGCATATATT TGACTGCAAT TGCAGCATTT GCAAGAAGAA GCAGAATAGA 
CACTTCATTG TTCCAGCTTC TCGCTTCAAG CTCCTGAAGG GAGCTGAGCA CATAACGACT 
TACACGTTCA ATACTCACAA AGCCCAGCAT ACCTTCTGTA AGAGATGTGG CGTTCAGAGC 
TTCTATACTC CACGATCAAA CCCCGGAGGC TTCGGAATTG CCCCCCACTG CCTGGATGAG 
GGCACTGTGC GGAGTATGGT CACTGAGGAA TTCAATGGCA GCGATTGGGA GAAGGCCATG 
AAAGAGCACA AGACCATCAA GAACATGTCT AAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_859067.2
CDS	63..881
Translation	MRRSRSSAAAKLRGQKRSGASAAPAASAAAALAPSATRTRRSASQAGSKSQAVEKPPSEKPRLRRSSPRAQEEGPGEPPPPELALLPPPPPPPPTPATPTSSASNLDLGEQRERWETFQKRQKLTSEGAAKLLLDTFEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNRHFIVPASRFKLLKGAEHITTYTFNTHKAQHTFCKRCGVQSFYTPRSNPGGFGIAPHCLDEGTVRSMVTEEFNGSDWEKAMKEHKTIKNMSKE

Target ORF information:

RefSeq Version	NM_181716.2
Organism	Homo sapiens(human)
Definition	Homo sapiens centromere protein V (CENPV), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181716.2

ORF Insert Sequence:

ATGCGGCGAT CGAGGAGCTC TGCGGCCGCC AAGCTGCGCG GGCAGAAGCG GTCCGGGGCC 
TCCGCGGCCC CCGCGGCCTC CGCGGCCGCT GCCTTGGCAC CCAGCGCCAC CCGCACACGG 
CGCTCCGCTA GCCAGGCCGG GAGCAAGAGC CAGGCGGTGG AGAAGCCGCC GTCGGAGAAG 
CCGCGGCTGA GGCGCTCGTC GCCGCGGGCC CAGGAGGAGG GCCCGGGGGA GCCGCCGCCG 
CCTGAGCTGG CGTTGCTCCC GCCACCGCCG CCGCCGCCGC CGACTCCCGC GACCCCGACG 
TCCTCGGCGT CCAACCTGGA CCTGGGCGAG CAGCGGGAGC GCTGGGAGAC GTTCCAGAAG 
CGGCAGAAGC TTACCTCCGA GGGTGCCGCC AAGCTCCTGC TAGACACCTT TGAATACCAG 
GGCCTGGTGA AGCACACAGG AGGCTGCCAC TGTGGAGCAG TTCGTTTTGA AGTTTGGGCC 
TCAGCAGACT TGCATATATT TGACTGCAAT TGCAGCATTT GCAAGAAGAA GCAGAATAGA 
CACTTCATTG TTCCAGCTTC TCGCTTCAAG CTCCTGAAGG GAGCTGAGCA CATAACGACT 
TACACGTTCA ATACTCACAA AGCCCAGCAT ACCTTCTGTA AGAGATGTGG CGTTCAGAGC 
TTCTATACTC CACGATCAAA CCCCGGAGGC TTCGGAATTG CCCCCCACTG CCTGGATGAG 
GGCACTGTGC GGAGTATGGT CACTGAGGAA TTCAATGGCA GCGATTGGGA GAAGGCCATG 
AAAGAGCACA AGACCATCAA GAACATGTCT AAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.
Neurobiology of aging34(1)357.e7-19(2013 Jan)
Ahmeti KB,Ajroud-Driss S,Al-Chalabi A,Andersen PM,Armstrong J,Birve A,Blauw HM,Brown RH,Bruijn L,Chen W,Chio A,Comeau MC,Cronin S,Diekstra FP,Soraya Gkazi A,Glass JD,Grab JD,Groen EJ,Haines JL,Hardiman O,Heller S,Huang J,Hung WY,,Jaworski JM,Jones A,Khan H,Landers JE,Langefeld CD,Leigh PN,Marion MC,McLaughlin RL,Meininger V,Melki J,Miller JW,Mora G,Pericak-Vance MA,Rampersaud E,Robberecht W,Russell LP,Salachas F,Saris CG,Shatunov A,Shaw CE,Siddique N,Siddique T,Smith BN,Sufit R,Topp S,Traynor BJ,Vance C,van Damme P,van den Berg LH,van Es MA,van Vught PW,Veldink JH,Yang Y,Zheng JG,

Identification of CENP-V as a novel microtubule-associating molecule that activates Src family kinases through SH3 domain interaction.
Genes to cells : devoted to molecular & cellular mechanisms14(12)1383-94(2009 Dec)
Honda Z,Suzuki T,Honda H

CENP-V is required for centromere organization, chromosome alignment and cytokinesis.
The EMBO journal27(19)2510-22(2008 Oct)
Tadeu AM,Ribeiro S,Johnston J,Goldberg I,Gerloff D,Earnshaw WC

Proteomic analysis of the mammalian nuclear pore complex.
The Journal of cell biology158(5)915-27(2002 Sep)
Cronshaw JM,Krutchinsky AN,Zhang W,Chait BT,Matunis MJ

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CENPV cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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