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ENPEP cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol ENPEP
Entrez Gene ID 2028
Full Name glutamyl aminopeptidase
Synonyms APA,CD249,gp160
General protein information
Preferred Names

glutamyl aminopeptidase

Names

glutamyl aminopeptidase
AP-A
EAP
aminopeptidase A
differentiation antigen gp160
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

4

4q25
Disorder MIM:

138297


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001977.3 NP_001968.3 glutamyl aminopeptidase
NM_001977.4 NP_001968.3 glutamyl aminopeptidase
XM_017007877.1 XP_016863366.1 glutamyl aminopeptidase isoform X1

Pathways from BioSystems


Homologies


Homo sapiens (human) ENPEP NP_001968.3
ENPEP XP_001090456.1
Mus musculus (house mouse) Enpep NP_031960.1
Drosophila melanogaster (fruit fly) CG32473 NP_731786.1
Gallus gallus (chicken) ENPEP XP_426327.3
Xenopus tropicalis (tropical clawed frog) enpep XP_002934295.1
Pan troglodytes (chimpanzee) ENPEP XP_517397.2
Canis lupus familiaris (dog) ENPEP XP_535696.2
Drosophila melanogaster (fruit fly) CG8773 NP_650273.2
Drosophila melanogaster (fruit fly) CG8774 NP_650274.2
Anopheles gambiae (African malaria mosquito) AgaP_AGAP003077 XP_003436384.1
Bos taurus (cattle) ENPEP NP_001033116.1
Rattus norvegicus (Norway rat) Enpep NP_071587.2
Danio rerio (zebrafish) enpep NP_001186660.1

Gene Ontology


Bibliography

Related articles in PubMed

Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer.
Chuang HY, Jiang JK, Yang MH, Wang HW, Li MC, Tsai CY, Jhang YY, Huang JC
Oncotarget8(13)21266-21280(2017 Mar)

Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.
Malinauskas M, Wallenius V, F?ndriks L, Casselbrant A
Journal of the renin-angiotensin-aldosterone system : JRAAS16(4)1101-8(2015 Dec)

Altered glutamyl-aminopeptidase activity and expression in renal neoplasms.
Blanco L, Sanz B, Perez I, S?nchez CE, C?ndenas ML, Pinto FM, Gil J, Casis L, L?pez JI, Larrinaga G
BMC cancer14386(2014 May)

Structural insights into central hypertension regulation by human aminopeptidase A.
Yang Y, Liu C, Lin YL, Li F
The Journal of biological chemistry288(35)25638-45(2013 Aug)

miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-?, CCNJ, and MEGF9.
Feliciano A, Castellvi J, Artero-Castro A, Leal JA, Romagosa C, Hern?ndez-Losa J, Peg V, Fabra A, Vidal F, Kondoh H, Ram?n Y Cajal S, Lleonart ME
PloS one8(10)e76247(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We suggest that APA enzymatic activity affects tumor initiation and cancer malignancy in a TWIST-dependent manner
Title: Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer.

The substrate Angiotensin II, the enzymes aminopeptidases-A, B, M as well as IRAP were detected in the jejunal mucosa.
Title: Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.

This study suggests a role for GAP in the neoplastic development of renal tumours and provides additional data for considering the activity and expression of this enzyme of interest in the diagnosis and prognosis of renal neoplasms.
Title: Altered glutamyl-aminopeptidase activity and expression in renal neoplasms.

These results explain the calcium-modulated substrate specificity of APA in central hypertension regulation
Title: Structural insights into central hypertension regulation by human aminopeptidase A.

miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-alpha, CCNJ, and MEGF9.
Title: miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-?, CCNJ, and MEGF9.

The following ENPEP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ENPEP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu94966 XM_017007877.1
Latest version!		 Homo sapiens glutamyl aminopeptidase (ENPEP), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 10-12 $307.30
$439.00
OHu29937 NM_001977.4
Latest version!		 Homo sapiens glutamyl aminopeptidase (ENPEP), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
View Old Accession Versions >>
OHu29937 NM_001977.3 Homo sapiens glutamyl aminopeptidase (ENPEP), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu94966
Clone ID Related Accession (Same CDS sequence) XM_017007877.1
Accession Version XM_017007877.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1800bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product glutamyl aminopeptidase isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGAGAACT GGGGACTCAT CACGTACAGA GAAACGAACC TGCTTTATGA CCCTAAGGAA 
TCAGCCTCAT CAAACCAACA GAGGGTGGCC ACTGTGGTTG CCCATGAACT TGTGCATCAG 
TGGTTTGGAA ATATTGTGAC CATGGACTGG TGGGAAGACT TGTGGCTAAA TGAAGGATTT 
GCTTCTTTCT TTGAGTTTCT GGGAGTAAAC CATGCAGAAA CAGACTGGCA AATGCGTGAC 
CAAATGTTAC TTGAAGATGT ATTACCTGTT CAAGAGGATG ATTCTTTGAT GTCTTCGCAT 
CCAATTATTG TGACTGTGAC AACCCCTGAT GAAATAACAT CTGTTTTTGA TGGAATATCC 
TATAGCAAGG GATCTTCTAT TTTGAGAATG CTTGAAGACT GGATAAAACC AGAGAATTTT 
CAAAAAGGAT GTCAGATGTA CTTGGAAAAA TACCAATTCA AGAATGCAAA AACTTCTGAT 
TTTTGGGCAG CACTGGAAGA GGCAAGTAGG CTACCAGTGA AAGAAGTAAT GGACACCTGG 
ACCAGACAGA TGGGTTATCC TGTGCTTAAC GTGAACGGTG TCAAGAACAT CACACAGAAA 
CGCTTTTTGT TGGACCCAAG AGCTAACCCT TCTCAGCCCC CTTCAGATCT TGGTTATACA 
TGGAATATCC CAGTTAAATG GACTGAAGAT AATATAACAA GCAGTGTGTT ATTTAATAGG 
TCAGAAAAAG AAGGAATCAC TTTGAACTCC TCTAATCCTA GTGGAAATGC TTTTCTCAAA 
ATAAACCCAG ATCATATTGG GTTTTATCGT GTAAATTATG AAGTAGCAAC TTGGGACTCG 
ATAGCTACAG CGCTCTCCTT GAACCACAAG ACATTTTCTT CAGCAGATCG TGCAAGTCTT 
ATTGATGATG CTTTTGCCTT GGCAAGAGCT CAACTTCTAG ATTATAAGGT GGCTTTGAAC 
TTGACCAAGT ATCTCAAAAG GGAAGAGAAT TTTTTACCAT GGCAGAGAGT AATTTCAGCT 
GTAACCTACA TCATTAGCAT GTTTGAAGAT GATAAAGAGC TATATCCTAT GATTGAGGAA 
TACTTCCAAG GTCAAGTGAA GCCTATTGCA GATTCTCTGG GATGGAATGA TGCTGGAGAC 
CATGTCACAA AGTTACTCCG TTCCTCCGTG TTAGGGTTTG CGTGCAAGAT GGGAGACAGA 
GAAGCCTTGA ACAATGCTTC CTCGTTATTT GAGCAGTGGC TAAATGGGAC TGTAAGCCTT 
CCCGTAAATC TCAGGCTTCT GGTGTATCGG TATGGGATGC AGAACTCTGG CAATGAGATT 
TCATGGAACT ACACTCTTGA GCAATACCAG AAAACTTCAT TAGCTCAAGA AAAAGAAAAA 
CTGCTGTATG GATTAGCATC AGTGAAGAAC GTTACTCTTT TGTCAAGGTA TTTGGATTTG 
CTCAAGGACA CGAACCTTAT TAAAACTCAG GATGTGTTTA CAGTCATTCG ATATATCTCA 
TATAACAGCT ATGGGAAGAA CATGGCCTGG AATTGGATAC AACTCAACTG GGACTATCTA 
GTCAACAGAT ATACACTCAA TAACAGAAAC CTTGGCCGAA TTGTCACAAT AGCAGAGCCA 
TTCAACACTG AACTGCAACT GTGGCAGATG GAGAGCTTTT TTGCAAAATA TCCACAAGCT 
GGAGCAGGAG AAAAACCTAG GGAACAAGTG CTGGAAACAG TGAAAAACAA TATAGAGTGG 
CTAAAACAAC ATAGAAACAC CATCAGAGAA TGGTTTTTTA ATTTACTTGA GAGTGGTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016863366.1
CDS95..1894
Translation

Target ORF information:

RefSeq Version XM_017007877.1
Organism Homo sapiens(human)
Definition Homo sapiens glutamyl aminopeptidase (ENPEP), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017007877.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGAGAACT GGGGACTCAT CACGTACAGA GAAACGAACC TGCTTTATGA CCCTAAGGAA 
TCAGCCTCAT CAAACCAACA GAGGGTGGCC ACTGTGGTTG CCCATGAACT TGTGCATCAG 
TGGTTTGGAA ATATTGTGAC CATGGACTGG TGGGAAGACT TGTGGCTAAA TGAAGGATTT 
GCTTCTTTCT TTGAGTTTCT GGGAGTAAAC CATGCAGAAA CAGACTGGCA AATGCGTGAC 
CAAATGTTAC TTGAAGATGT ATTACCTGTT CAAGAGGATG ATTCTTTGAT GTCTTCGCAT 
CCAATTATTG TGACTGTGAC AACCCCTGAT GAAATAACAT CTGTTTTTGA TGGAATATCC 
TATAGCAAGG GATCTTCTAT TTTGAGAATG CTTGAAGACT GGATAAAACC AGAGAATTTT 
CAAAAAGGAT GTCAGATGTA CTTGGAAAAA TACCAATTCA AGAATGCAAA AACTTCTGAT 
TTTTGGGCAG CACTGGAAGA GGCAAGTAGG CTACCAGTGA AAGAAGTAAT GGACACCTGG 
ACCAGACAGA TGGGTTATCC TGTGCTTAAC GTGAACGGTG TCAAGAACAT CACACAGAAA 
CGCTTTTTGT TGGACCCAAG AGCTAACCCT TCTCAGCCCC CTTCAGATCT TGGTTATACA 
TGGAATATCC CAGTTAAATG GACTGAAGAT AATATAACAA GCAGTGTGTT ATTTAATAGG 
TCAGAAAAAG AAGGAATCAC TTTGAACTCC TCTAATCCTA GTGGAAATGC TTTTCTCAAA 
ATAAACCCAG ATCATATTGG GTTTTATCGT GTAAATTATG AAGTAGCAAC TTGGGACTCG 
ATAGCTACAG CGCTCTCCTT GAACCACAAG ACATTTTCTT CAGCAGATCG TGCAAGTCTT 
ATTGATGATG CTTTTGCCTT GGCAAGAGCT CAACTTCTAG ATTATAAGGT GGCTTTGAAC 
TTGACCAAGT ATCTCAAAAG GGAAGAGAAT TTTTTACCAT GGCAGAGAGT AATTTCAGCT 
GTAACCTACA TCATTAGCAT GTTTGAAGAT GATAAAGAGC TATATCCTAT GATTGAGGAA 
TACTTCCAAG GTCAAGTGAA GCCTATTGCA GATTCTCTGG GATGGAATGA TGCTGGAGAC 
CATGTCACAA AGTTACTCCG TTCCTCCGTG TTAGGGTTTG CGTGCAAGAT GGGAGACAGA 
GAAGCCTTGA ACAATGCTTC CTCGTTATTT GAGCAGTGGC TAAATGGGAC TGTAAGCCTT 
CCCGTAAATC TCAGGCTTCT GGTGTATCGG TATGGGATGC AGAACTCTGG CAATGAGATT 
TCATGGAACT ACACTCTTGA GCAATACCAG AAAACTTCAT TAGCTCAAGA AAAAGAAAAA 
CTGCTGTATG GATTAGCATC AGTGAAGAAC GTTACTCTTT TGTCAAGGTA TTTGGATTTG 
CTCAAGGACA CGAACCTTAT TAAAACTCAG GATGTGTTTA CAGTCATTCG ATATATCTCA 
TATAACAGCT ATGGGAAGAA CATGGCCTGG AATTGGATAC AACTCAACTG GGACTATCTA 
GTCAACAGAT ATACACTCAA TAACAGAAAC CTTGGCCGAA TTGTCACAAT AGCAGAGCCA 
TTCAACACTG AACTGCAACT GTGGCAGATG GAGAGCTTTT TTGCAAAATA TCCACAAGCT 
GGAGCAGGAG AAAAACCTAG GGAACAAGTG CTGGAAACAG TGAAAAACAA TATAGAGTGG 
CTAAAACAAC ATAGAAACAC CATCAGAGAA TGGTTTTTTA ATTTACTTGA GAGTGGTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29937
Clone ID Related Accession (Same CDS sequence) NM_001977.3 , NM_001977.4
Accession Version NM_001977.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2874bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-15
Organism Homo sapiens(human)
Product glutamyl aminopeptidase
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB070526.1, BC094770.1, AC098798.4, BG400415.1, AL568777.3 and AI640493.1. On Mar 15, 2007 this sequence version replaced NM_001977.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM888273.1, AM888274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC 
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG 
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC 
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC 
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC 
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG 
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT 
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC 
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC 
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC 
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG 
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA 
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC 
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA 
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA 
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT 
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG 
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC 
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT 
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT 
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG 
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT 
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC 
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA 
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG 
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA 
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT 
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT 
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA 
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC 
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT 
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT 
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC 
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC 
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC 
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC 
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC 
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA 
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG 
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG 
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG 
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC 
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC 
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC 
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA 
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA 
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001968.3
CDS343..3216
Translation

Target ORF information:

RefSeq Version NM_001977.3
Organism Homo sapiens(human)
Definition Homo sapiens glutamyl aminopeptidase (ENPEP), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001977.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC 
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG 
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC 
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC 
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC 
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG 
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT 
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC 
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC 
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC 
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG 
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA 
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC 
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA 
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA 
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT 
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG 
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC 
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT 
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT 
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG 
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT 
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC 
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA 
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG 
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA 
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT 
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT 
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA 
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC 
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT 
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT 
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC 
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC 
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC 
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC 
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC 
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA 
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG 
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG 
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG 
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC 
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC 
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC 
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA 
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA 
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29937
Clone ID Related Accession (Same CDS sequence) NM_001977.3 , NM_001977.4
Accession Version NM_001977.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2874bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-30
Organism Homo sapiens(human)
Product glutamyl aminopeptidase
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC094770.1, AC098798.4, BG400415.1, AL568777.3, AI640493.1 and AC017068.7. On Nov 23, 2018 this sequence version replaced NM_001977.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM888273.1, AM888274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265162.10/ ENSP00000265162.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC 
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG 
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC 
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC 
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC 
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG 
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT 
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC 
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC 
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC 
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG 
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA 
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC 
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA 
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA 
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT 
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG 
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC 
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT 
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT 
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG 
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT 
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC 
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA 
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG 
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA 
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT 
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT 
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA 
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC 
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT 
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT 
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC 
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC 
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC 
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC 
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC 
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA 
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG 
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG 
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG 
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC 
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC 
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC 
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA 
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA 
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001968.3
CDS261..3134
Translation

Target ORF information:

RefSeq Version NM_001977.4
Organism Homo sapiens(human)
Definition Homo sapiens glutamyl aminopeptidase (ENPEP), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001977.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC 
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG 
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC 
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC 
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC 
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG 
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT 
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC 
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC 
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC 
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG 
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA 
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC 
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA 
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA 
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT 
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG 
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC 
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT 
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT 
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG 
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT 
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC 
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA 
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG 
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA 
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT 
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT 
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA 
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC 
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT 
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT 
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC 
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC 
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC 
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC 
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC 
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA 
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG 
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG 
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG 
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC 
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC 
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC 
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA 
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA 
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer.
Oncotarget8(13)21266-21280(2017 Mar)
Chuang HY,Jiang JK,Yang MH,Wang HW,Li MC,Tsai CY,Jhang YY,Huang JC


book

Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.
Journal of the renin-angiotensin-aldosterone system : JRAAS16(4)1101-8(2015 Dec)
Malinauskas M,Wallenius V,F?ndriks L,Casselbrant A


book

Altered glutamyl-aminopeptidase activity and expression in renal neoplasms.
BMC cancer14386(2014 May)
Blanco L,Sanz B,Perez I,S?nchez CE,C?ndenas ML,Pinto FM,Gil J,Casis L,L?pez JI,Larrinaga G


book

Structural insights into central hypertension regulation by human aminopeptidase A.
The Journal of biological chemistry288(35)25638-45(2013 Aug)
Yang Y,Liu C,Lin YL,Li F


book

miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-?, CCNJ, and MEGF9.
PloS one8(10)e76247(2013)
Feliciano A,Castellvi J,Artero-Castro A,Leal JA,Romagosa C,Hern?ndez-Losa J,Peg V,Fabra A,Vidal F,Kondoh H,Ram?n Y Cajal S,Lleonart ME