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ENPEP cDNA ORF clone, Homo sapiens (human)

Gene Symbol ENPEP
Entrez Gene ID 2028
Full Name glutamyl aminopeptidase (aminopeptidase A)
Synonyms APA, CD249, gp160
General protein information
Preferred Names
glutamyl aminopeptidase
Names
glutamyl aminopeptidase
EAP
AP-A
aminopeptidase A
differentiation antigen gp160
NP_001968.3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q25

Summary lac of sum
Disorder MIM:

138297


mRNA and Protein(s)

mRNA Protein Name
NM_001977 NP_001968 glutamyl aminopeptidase



Homo sapiens (human) ENPEP NP_001968.3
Pan troglodytes (chimpanzee) ENPEP XP_517397.2
Macaca mulatta (Rhesus monkey) ENPEP XP_001090456.1
Canis lupus familiaris (dog) ENPEP XP_535696.2
Bos taurus (cattle) ENPEP NP_001033116.1
Mus musculus (house mouse) Enpep NP_031960.1
Rattus norvegicus (Norway rat) Enpep NP_071587.2
Gallus gallus (chicken) ENPEP XP_426327.3
Danio rerio (zebrafish) enpep NP_001186660.1
Drosophila melanogaster (fruit fly) CG8773 NP_650273.2
Drosophila melanogaster (fruit fly) CG8774 NP_650274.2
Drosophila melanogaster (fruit fly) CG32473 NP_731786.1
Xenopus (Silurana) tropicalis (western clawed frog) enpep XP_002934295.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ENPEP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ENPEP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu29937 NM_001977 Homo sapiens glutamyl aminopeptidase (aminopeptidase A) (ENPEP), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu29937
Clone ID Related Accession (Same CDS sequence) NM_001977
Accession Version NM_001977.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2874bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glutamyl aminopeptidase
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB070526.1, BC094770.1, AC098798.4, BG400415.1, AL568777.3 and AI640493.1. On Mar 15, 2007 this sequence version replaced gi:36951115. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM888273.1, AM888274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001968.3
CDS343..3216
Misc Feature(1)319..321(+)
Misc Feature(2)397..459(+)
Misc Feature(3)616..1788(+)
Misc Feature(4)640..1977(+)
Misc Feature(5)1411..1425(+)
Misc Feature(6)1519..1590(+)
Misc Feature(7)1777..1779(+)
Misc Feature(8)2188..3141(+)
Exon (1)1..986
Gene:ENPEP
Gene Synonym:
Exon (2)987..1128
Gene:ENPEP
Gene Synonym:
Exon (3)1129..1260
Gene:ENPEP
Gene Synonym:
Exon (4)1261..1381
Gene:ENPEP
Gene Synonym:
Exon (5)1382..1536
Gene:ENPEP
Gene Synonym:
Exon (6)1537..1650
Gene:ENPEP
Gene Synonym:
Exon (7)1651..1785
Gene:ENPEP
Gene Synonym:
Exon (8)1786..1851
Gene:ENPEP
Gene Synonym:
Exon (9)1852..1917
Gene:ENPEP
Gene Synonym:
Exon (10)1918..2069
Gene:ENPEP
Gene Synonym:
Exon (11)2070..2149
Gene:ENPEP
Gene Synonym:
Exon (12)2150..2286
Gene:ENPEP
Gene Synonym:
Exon (13)2287..2342
Gene:ENPEP
Gene Synonym:
Exon (14)2343..2493
Gene:ENPEP
Gene Synonym:
Exon (15)2494..2567
Gene:ENPEP
Gene Synonym:
Exon (16)2568..2672
Gene:ENPEP
Gene Synonym:
Exon (17)2673..2843
Gene:ENPEP
Gene Synonym:
Exon (18)2844..2984
Gene:ENPEP
Gene Synonym:
Exon (19)2985..3063
Gene:ENPEP
Gene Synonym:
Exon (20)3064..4995
Gene:ENPEP
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001977
Organism Homo sapiens (human)
Definition Homo sapiens glutamyl aminopeptidase (aminopeptidase A) (ENPEP), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001977

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Structural insights into central hypertension regulation by human aminopeptidase A
J. Biol. Chem. 288 (35), 25638-25645 (2013)
Yang Y, Liu C, Lin YL and Li F.


book

Does the aminopeptidase A have prognostic and diagnostic value in Chagas disease and other dilated cardiomyopathies?
J. Cardiovasc. Pharmacol. 58 (4), 374-379 (2011)
Wang Y, Moreira Mda C, Heringer-Walther S, Khan A, Schultheiss HP, Wessel N, Siems WE and Walther T.


book

Human metabolic individuality in biomedical and pharmaceutical research
Nature 477 (7362), 54-60 (2011)
Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wagele B, Altmaier E, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmuller G, Kottgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Romisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N and Gieger C.


book

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
Nat. Genet. 43 (6), 531-538 (2011)
Kato N, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT, Chen CH, Zhang Y, Yamamoto K, Katsuya T, Yokota M, Kim YJ, Ong RT, Nabika T, Gu D, Chang LC, Kokubo Y, Huang W, Ohnaka K, Yamori Y, Nakashima E, Jaquish CE, Lee JY, Seielstad M, Isono M, Hixson JE, Chen YT, Miki T, Zhou X, Sugiyama T, Jeon JP, Liu JJ, Takayanagi R, Kim SS, Aung T, Sung YJ, Zhang X, Wong TY, Han BG, Kobayashi S, Ogihara T, Zhu D, Iwai N, Wu JY, Teo YY, Tai ES, Cho YS and He J.


book

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts
Hum. Mol. Genet. 19 (12), 2497-2506 (2010)
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS and Riley BP.


book

The in vivo metabolism of cholecystokinin (CCK-8) is essentially ensured by aminopeptidase A
Peptides 17 (4), 601-607 (1996)
Migaud M, Durieux C, Viereck J, Soroca-Lucas E, Fournie-Zaluski MC and Roques BP.


book

cDNA cloning and expression of human glutamyl aminopeptidase (aminopeptidase A)
Genomics 17 (3), 657-664 (1993)
Li L, Wang J and Cooper MD.


book

Molecular cloning of the human kidney differentiation antigen gp160: human aminopeptidase A
Proc. Natl. Acad. Sci. U.S.A. 90 (15), 7069-7073 (1993)
Nanus DM, Engelstein D, Gastl GA, Gluck L, Vidal MJ, Morrison M, Finstad CL, Bander NH and Albino AP.


book

Receptor-mediated induction of aminopeptidase A (APA) of human glomerular epithelial cells (HGEC) by glucocorticoids
FEBS Lett. 294 (3), 171-174 (1991)
Stefanovic V, Vlahovic P, Ardaillou N and Ardaillou R.


book

Antiproliferative and antitumor effects of alpha-interferon in renal cell carcinomas: correlation with the expression of a kidney-associated differentiation glycoprotein
Cancer Res. 50 (14), 4190-4194 (1990)
Nanus DM, Pfeffer LM, Bander NH, Bahri S and Albino AP.


 
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