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ENPEP cDNA ORF clone, Homo sapiens(Human)

Gene Symbol ENPEP
Entrez Gene ID 2028
Full Name glutamyl aminopeptidase
Synonyms APA,CD249,gp160
General protein information
Preferred Names

glutamyl aminopeptidase

Names

glutamyl aminopeptidase
AP-A
EAP
aminopeptidase A
differentiation antigen gp160

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

4

4q25

Disorder MIM:

138297


mRNA and Protein(s)

mRNA Protein Name
NM_001977.3 NP_001968.3 glutamyl aminopeptidase
XM_017007877.1 XP_016863366.1 glutamyl aminopeptidase isoform X1



Macaca mulatta (rhesus monkey) ENPEP XP_001090456.1
Homo sapiens (human) ENPEP NP_001968.3
Mus musculus (house mouse) Enpep NP_031960.1
Drosophila melanogaster (fruit fly) CG32473 NP_731786.1
Gallus gallus (chicken) ENPEP XP_426327.3
Xenopus tropicalis (tropical clawed frog) enpep XP_002934295.1
Pan troglodytes (chimpanzee) ENPEP XP_517397.2
Canis lupus familiaris (dog) ENPEP XP_535696.2
Drosophila melanogaster (fruit fly) CG8773 NP_650273.2
Drosophila melanogaster (fruit fly) CG8774 NP_650274.2
Anopheles gambiae (African malaria mosquito) AgaP_AGAP003077 XP_003436384.1
Bos taurus (cattle) ENPEP NP_001033116.1
Rattus norvegicus (Norway rat) Enpep NP_071587.2
Danio rerio (zebrafish) enpep NP_001186660.1


Related articles in PubMed

Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.
Malinauskas M, Wallenius V, Fändriks L, Casselbrant A
Journal of the renin-angiotensin-aldosterone system : JRAAS16(4)1101-8(2015 Dec)

Altered glutamyl-aminopeptidase activity and expression in renal neoplasms.
Blanco L, Sanz B, Perez I, Sánchez CE, Cándenas ML, Pinto FM, Gil J, Casis L, López JI, Larrinaga G
BMC cancer14386(2014 May)

Structural insights into central hypertension regulation by human aminopeptidase A.
Yang Y, Liu C, Lin YL, Li F
The Journal of biological chemistry288(35)25638-45(2013 Aug)

miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-α, CCNJ, and MEGF9.
Feliciano A, Castellvi J, Artero-Castro A, Leal JA, Romagosa C, Hernández-Losa J, Peg V, Fabra A, Vidal F, Kondoh H, Ramón Y Cajal S, Lleonart ME
PloS one8(10)e76247(2013)

Human metabolic individuality in biomedical and pharmaceutical research.
Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E, , Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C
Nature477(7362)54-60(2011 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The substrate Angiotensin II, the enzymes aminopeptidases-A, B, M as well as IRAP were detected in the jejunal mucosa.
Title: Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.

This study suggests a role for GAP in the neoplastic development of renal tumours and provides additional data for considering the activity and expression of this enzyme of interest in the diagnosis and prognosis of renal neoplasms.
Title: Altered glutamyl-aminopeptidase activity and expression in renal neoplasms.

These results explain the calcium-modulated substrate specificity of APA in central hypertension regulation
Title: Structural insights into central hypertension regulation by human aminopeptidase A.

miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-alpha, CCNJ, and MEGF9.
Title: miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-α, CCNJ, and MEGF9.

There was no significant alteration in plasma APA activity in the patients with Chagas disease or dilated cardiomyopathies, as compared with that in health controls
Title: Does the aminopeptidase A have prognostic and diagnostic value in Chagas disease and other dilated cardiomyopathies?

The following ENPEP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ENPEP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu94966 XM_017007877.1
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Homo sapiens glutamyl aminopeptidase (ENPEP), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 10-12 $307.30
$439.00
OHu29937 NM_001977.3
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Homo sapiens glutamyl aminopeptidase (ENPEP), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu94966
Clone ID Related Accession (Same CDS sequence) XM_017007877.1
Accession Version XM_017007877.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1800bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product glutamyl aminopeptidase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGAGAACT GGGGACTCAT CACGTACAGA GAAACGAACC TGCTTTATGA CCCTAAGGAA 
TCAGCCTCAT CAAACCAACA GAGGGTGGCC ACTGTGGTTG CCCATGAACT TGTGCATCAG
TGGTTTGGAA ATATTGTGAC CATGGACTGG TGGGAAGACT TGTGGCTAAA TGAAGGATTT
GCTTCTTTCT TTGAGTTTCT GGGAGTAAAC CATGCAGAAA CAGACTGGCA AATGCGTGAC
CAAATGTTAC TTGAAGATGT ATTACCTGTT CAAGAGGATG ATTCTTTGAT GTCTTCGCAT
CCAATTATTG TGACTGTGAC AACCCCTGAT GAAATAACAT CTGTTTTTGA TGGAATATCC
TATAGCAAGG GATCTTCTAT TTTGAGAATG CTTGAAGACT GGATAAAACC AGAGAATTTT
CAAAAAGGAT GTCAGATGTA CTTGGAAAAA TACCAATTCA AGAATGCAAA AACTTCTGAT
TTTTGGGCAG CACTGGAAGA GGCAAGTAGG CTACCAGTGA AAGAAGTAAT GGACACCTGG
ACCAGACAGA TGGGTTATCC TGTGCTTAAC GTGAACGGTG TCAAGAACAT CACACAGAAA
CGCTTTTTGT TGGACCCAAG AGCTAACCCT TCTCAGCCCC CTTCAGATCT TGGTTATACA
TGGAATATCC CAGTTAAATG GACTGAAGAT AATATAACAA GCAGTGTGTT ATTTAATAGG
TCAGAAAAAG AAGGAATCAC TTTGAACTCC TCTAATCCTA GTGGAAATGC TTTTCTCAAA
ATAAACCCAG ATCATATTGG GTTTTATCGT GTAAATTATG AAGTAGCAAC TTGGGACTCG
ATAGCTACAG CGCTCTCCTT GAACCACAAG ACATTTTCTT CAGCAGATCG TGCAAGTCTT
ATTGATGATG CTTTTGCCTT GGCAAGAGCT CAACTTCTAG ATTATAAGGT GGCTTTGAAC
TTGACCAAGT ATCTCAAAAG GGAAGAGAAT TTTTTACCAT GGCAGAGAGT AATTTCAGCT
GTAACCTACA TCATTAGCAT GTTTGAAGAT GATAAAGAGC TATATCCTAT GATTGAGGAA
TACTTCCAAG GTCAAGTGAA GCCTATTGCA GATTCTCTGG GATGGAATGA TGCTGGAGAC
CATGTCACAA AGTTACTCCG TTCCTCCGTG TTAGGGTTTG CGTGCAAGAT GGGAGACAGA
GAAGCCTTGA ACAATGCTTC CTCGTTATTT GAGCAGTGGC TAAATGGGAC TGTAAGCCTT
CCCGTAAATC TCAGGCTTCT GGTGTATCGG TATGGGATGC AGAACTCTGG CAATGAGATT
TCATGGAACT ACACTCTTGA GCAATACCAG AAAACTTCAT TAGCTCAAGA AAAAGAAAAA
CTGCTGTATG GATTAGCATC AGTGAAGAAC GTTACTCTTT TGTCAAGGTA TTTGGATTTG
CTCAAGGACA CGAACCTTAT TAAAACTCAG GATGTGTTTA CAGTCATTCG ATATATCTCA
TATAACAGCT ATGGGAAGAA CATGGCCTGG AATTGGATAC AACTCAACTG GGACTATCTA
GTCAACAGAT ATACACTCAA TAACAGAAAC CTTGGCCGAA TTGTCACAAT AGCAGAGCCA
TTCAACACTG AACTGCAACT GTGGCAGATG GAGAGCTTTT TTGCAAAATA TCCACAAGCT
GGAGCAGGAG AAAAACCTAG GGAACAAGTG CTGGAAACAG TGAAAAACAA TATAGAGTGG
CTAAAACAAC ATAGAAACAC CATCAGAGAA TGGTTTTTTA ATTTACTTGA GAGTGGTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016863366.1
CDS95..1894
Translation

Target ORF information:

RefSeq Version XM_017007877.1
Organism Homo sapiens(Human)
Definition Homo sapiens glutamyl aminopeptidase (ENPEP), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017007877.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGAGAACT GGGGACTCAT CACGTACAGA GAAACGAACC TGCTTTATGA CCCTAAGGAA 
TCAGCCTCAT CAAACCAACA GAGGGTGGCC ACTGTGGTTG CCCATGAACT TGTGCATCAG
TGGTTTGGAA ATATTGTGAC CATGGACTGG TGGGAAGACT TGTGGCTAAA TGAAGGATTT
GCTTCTTTCT TTGAGTTTCT GGGAGTAAAC CATGCAGAAA CAGACTGGCA AATGCGTGAC
CAAATGTTAC TTGAAGATGT ATTACCTGTT CAAGAGGATG ATTCTTTGAT GTCTTCGCAT
CCAATTATTG TGACTGTGAC AACCCCTGAT GAAATAACAT CTGTTTTTGA TGGAATATCC
TATAGCAAGG GATCTTCTAT TTTGAGAATG CTTGAAGACT GGATAAAACC AGAGAATTTT
CAAAAAGGAT GTCAGATGTA CTTGGAAAAA TACCAATTCA AGAATGCAAA AACTTCTGAT
TTTTGGGCAG CACTGGAAGA GGCAAGTAGG CTACCAGTGA AAGAAGTAAT GGACACCTGG
ACCAGACAGA TGGGTTATCC TGTGCTTAAC GTGAACGGTG TCAAGAACAT CACACAGAAA
CGCTTTTTGT TGGACCCAAG AGCTAACCCT TCTCAGCCCC CTTCAGATCT TGGTTATACA
TGGAATATCC CAGTTAAATG GACTGAAGAT AATATAACAA GCAGTGTGTT ATTTAATAGG
TCAGAAAAAG AAGGAATCAC TTTGAACTCC TCTAATCCTA GTGGAAATGC TTTTCTCAAA
ATAAACCCAG ATCATATTGG GTTTTATCGT GTAAATTATG AAGTAGCAAC TTGGGACTCG
ATAGCTACAG CGCTCTCCTT GAACCACAAG ACATTTTCTT CAGCAGATCG TGCAAGTCTT
ATTGATGATG CTTTTGCCTT GGCAAGAGCT CAACTTCTAG ATTATAAGGT GGCTTTGAAC
TTGACCAAGT ATCTCAAAAG GGAAGAGAAT TTTTTACCAT GGCAGAGAGT AATTTCAGCT
GTAACCTACA TCATTAGCAT GTTTGAAGAT GATAAAGAGC TATATCCTAT GATTGAGGAA
TACTTCCAAG GTCAAGTGAA GCCTATTGCA GATTCTCTGG GATGGAATGA TGCTGGAGAC
CATGTCACAA AGTTACTCCG TTCCTCCGTG TTAGGGTTTG CGTGCAAGAT GGGAGACAGA
GAAGCCTTGA ACAATGCTTC CTCGTTATTT GAGCAGTGGC TAAATGGGAC TGTAAGCCTT
CCCGTAAATC TCAGGCTTCT GGTGTATCGG TATGGGATGC AGAACTCTGG CAATGAGATT
TCATGGAACT ACACTCTTGA GCAATACCAG AAAACTTCAT TAGCTCAAGA AAAAGAAAAA
CTGCTGTATG GATTAGCATC AGTGAAGAAC GTTACTCTTT TGTCAAGGTA TTTGGATTTG
CTCAAGGACA CGAACCTTAT TAAAACTCAG GATGTGTTTA CAGTCATTCG ATATATCTCA
TATAACAGCT ATGGGAAGAA CATGGCCTGG AATTGGATAC AACTCAACTG GGACTATCTA
GTCAACAGAT ATACACTCAA TAACAGAAAC CTTGGCCGAA TTGTCACAAT AGCAGAGCCA
TTCAACACTG AACTGCAACT GTGGCAGATG GAGAGCTTTT TTGCAAAATA TCCACAAGCT
GGAGCAGGAG AAAAACCTAG GGAACAAGTG CTGGAAACAG TGAAAAACAA TATAGAGTGG
CTAAAACAAC ATAGAAACAC CATCAGAGAA TGGTTTTTTA ATTTACTTGA GAGTGGTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29937
Clone ID Related Accession (Same CDS sequence) NM_001977.3
Accession Version NM_001977.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2874bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-29
Organism Homo sapiens(Human)
Product glutamyl aminopeptidase
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB070526.1, BC094770.1, AC098798.4, BG400415.1, AL568777.3 and AI640493.1. On Mar 15, 2007 this sequence version replaced NM_001977.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM888273.1, AM888274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001968.3
CDS343..3216
Misc Feature(1)319..321
Misc Feature(2)397..459
Misc Feature(3)616..1788
Misc Feature(4)640..1977
Misc Feature(5)1411..1425
Misc Feature(6)order(1519..1521,1531..1533,1588..1590)
Misc Feature(7)1777..1779
Misc Feature(8)2191..3135
Exon (1)1..986
Exon (2)987..1128
Exon (3)1129..1260
Exon (4)1261..1381
Exon (5)1382..1536
Exon (6)1537..1650
Exon (7)1651..1785
Exon (8)1786..1851
Exon (9)1852..1917
Exon (10)1918..2069
Exon (11)2070..2149
Exon (12)2150..2286
Exon (13)2287..2342
Exon (14)2343..2493
Exon (15)2494..2567
Exon (16)2568..2672
Exon (17)2673..2843
Exon (18)2844..2984
Exon (19)2985..3063
Exon (20)3064..4995
Translation

Target ORF information:

RefSeq Version NM_001977.3
Organism Homo sapiens(Human)
Definition Homo sapiens glutamyl aminopeptidase (ENPEP), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001977.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGAACTTTG CGGAGAGAGA GGGCTCTAAG AGATACTGCA TTCAAACGAA ACATGTGGCC 
ATTCTCTGTG CGGTGGTGGT GGGTGTAGGA TTAATAGTGG GACTTGCCGT GGGCTTGACC
AGATCGTGTG ACTCCAGCGG GGACGGCGGG CCGGGCACTG CGCCAGCTCC TTCCCACCTG
CCTTCTTCCA CGGCCAGCCC CTCAGGTCCT CCTGCCCAGG ACCAGGACAT CTGCCCGGCC
AGTGAGGATG AGAGCGGACA GTGGAAAAAC TTTCGACTGC CGGACTTCGT CAACCCAGTC
CACTACGACC TGCACGTGAA GCCCCTGTTG GAGGAGGACA CCTACACGGG CACCGTGAGC
ATCTCCATCA ACCTGAGCGC TCCCACCCGG TACCTGTGGC TGCACCTCCG GGAGACCAGG
ATCACCCGGC TCCCGGAGCT GAAGAGGCCC TCTGGGGACC AGGTGCAAGT CCGGAGGTGT
TTCGAGTACA AAAAGCAGGA GTACGTGGTG GTCGAGGCGG AGGAAGAGCT TACCCCCAGC
AGTGGAGATG GCCTGTATCT CCTGACCATG GAGTTCGCCG GCTGGCTGAA CGGCTCCCTC
GTGGGATTTT ATAGAACCAC CTACACGGAG AACGGACAAG TCAAGAGCAT AGTGGCCACC
GATCATGAAC CAACAGATGC CAGGAAATCT TTTCCTTGTT TTGATGAGCC CAACAAAAAG
GCAACTTATA CAATATCTAT CACCCATCCC AAAGAATACG GAGCACTTTC AAATATGCCA
GTGGCGAAAG AAGAGTCAGT GGATGATAAA TGGACTCGAA CAACTTTTGA GAAGTCTGTC
CCCATGAGCA CGTACCTGGT GTGCTTTGCT GTACATCAAT TTGACTCTGT AAAGAGAATA
TCAAATAGTG GAAAACCTCT TACAATTTAT GTCCAGCCAG AGCAAAAGCA CACAGCCGAA
TATGCTGCAA ACATAACTAA AAGTGTGTTT GATTATTTTG AAGAATACTT TGCTATGAAT
TATTCTCTTC CTAAATTAGA TAAAATCGCT ATTCCAGATT TTGGCACTGG TGCCATGGAG
AACTGGGGAC TCATCACGTA CAGAGAAACG AACCTGCTTT ATGACCCTAA GGAATCAGCC
TCATCAAACC AACAGAGGGT GGCCACTGTG GTTGCCCATG AACTTGTGCA TCAGTGGTTT
GGAAATATTG TGACCATGGA CTGGTGGGAA GACTTGTGGC TAAATGAAGG ATTTGCTTCT
TTCTTTGAGT TTCTGGGAGT AAACCATGCA GAAACAGACT GGCAAATGCG TGACCAAATG
TTACTTGAAG ATGTATTACC TGTTCAAGAG GATGATTCTT TGATGTCTTC GCATCCAATT
ATTGTGACTG TGACAACCCC TGATGAAATA ACATCTGTTT TTGATGGAAT ATCCTATAGC
AAGGGATCTT CTATTTTGAG AATGCTTGAA GACTGGATAA AACCAGAGAA TTTTCAAAAA
GGATGTCAGA TGTACTTGGA AAAATACCAA TTCAAGAATG CAAAAACTTC TGATTTTTGG
GCAGCACTGG AAGAGGCAAG TAGGCTACCA GTGAAAGAAG TAATGGACAC CTGGACCAGA
CAGATGGGTT ATCCTGTGCT TAACGTGAAC GGTGTCAAGA ACATCACACA GAAACGCTTT
TTGTTGGACC CAAGAGCTAA CCCTTCTCAG CCCCCTTCAG ATCTTGGTTA TACATGGAAT
ATCCCAGTTA AATGGACTGA AGATAATATA ACAAGCAGTG TGTTATTTAA TAGGTCAGAA
AAAGAAGGAA TCACTTTGAA CTCCTCTAAT CCTAGTGGAA ATGCTTTTCT CAAAATAAAC
CCAGATCATA TTGGGTTTTA TCGTGTAAAT TATGAAGTAG CAACTTGGGA CTCGATAGCT
ACAGCGCTCT CCTTGAACCA CAAGACATTT TCTTCAGCAG ATCGTGCAAG TCTTATTGAT
GATGCTTTTG CCTTGGCAAG AGCTCAACTT CTAGATTATA AGGTGGCTTT GAACTTGACC
AAGTATCTCA AAAGGGAAGA GAATTTTTTA CCATGGCAGA GAGTAATTTC AGCTGTAACC
TACATCATTA GCATGTTTGA AGATGATAAA GAGCTATATC CTATGATTGA GGAATACTTC
CAAGGTCAAG TGAAGCCTAT TGCAGATTCT CTGGGATGGA ATGATGCTGG AGACCATGTC
ACAAAGTTAC TCCGTTCCTC CGTGTTAGGG TTTGCGTGCA AGATGGGAGA CAGAGAAGCC
TTGAACAATG CTTCCTCGTT ATTTGAGCAG TGGCTAAATG GGACTGTAAG CCTTCCCGTA
AATCTCAGGC TTCTGGTGTA TCGGTATGGG ATGCAGAACT CTGGCAATGA GATTTCATGG
AACTACACTC TTGAGCAATA CCAGAAAACT TCATTAGCTC AAGAAAAAGA AAAACTGCTG
TATGGATTAG CATCAGTGAA GAACGTTACT CTTTTGTCAA GGTATTTGGA TTTGCTCAAG
GACACGAACC TTATTAAAAC TCAGGATGTG TTTACAGTCA TTCGATATAT CTCATATAAC
AGCTATGGGA AGAACATGGC CTGGAATTGG ATACAACTCA ACTGGGACTA TCTAGTCAAC
AGATATACAC TCAATAACAG AAACCTTGGC CGAATTGTCA CAATAGCAGA GCCATTCAAC
ACTGAACTGC AACTGTGGCA GATGGAGAGC TTTTTTGCAA AATATCCACA AGCTGGAGCA
GGAGAAAAAC CTAGGGAACA AGTGCTGGAA ACAGTGAAAA ACAATATAGA GTGGCTAAAA
CAACATAGAA ACACCATCAG AGAATGGTTT TTTAATTTAC TTGAGAGTGG TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.
Journal of the renin-angiotensin-aldosterone system : JRAAS16(4)1101-8(2015 Dec)
Malinauskas M,Wallenius V,Fändriks L,Casselbrant A


book

Altered glutamyl-aminopeptidase activity and expression in renal neoplasms.
BMC cancer14386(2014 May)
Blanco L,Sanz B,Perez I,Sánchez CE,Cándenas ML,Pinto FM,Gil J,Casis L,López JI,Larrinaga G


book

Structural insights into central hypertension regulation by human aminopeptidase A.
The Journal of biological chemistry288(35)25638-45(2013 Aug)
Yang Y,Liu C,Lin YL,Li F


book

miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-α, CCNJ, and MEGF9.
PloS one8(10)e76247(2013)
Feliciano A,Castellvi J,Artero-Castro A,Leal JA,Romagosa C,Hernández-Losa J,Peg V,Fabra A,Vidal F,Kondoh H,Ramón Y Cajal S,Lleonart ME


book

Human metabolic individuality in biomedical and pharmaceutical research.
Nature477(7362)54-60(2011 Aug)
Suhre K,Shin SY,Petersen AK,Mohney RP,Meredith D,Wägele B,Altmaier E,,Deloukas P,Erdmann J,Grundberg E,Hammond CJ,de Angelis MH,Kastenmüller G,Köttgen A,Kronenberg F,Mangino M,Meisinger C,Meitinger T,Mewes HW,Milburn MV,Prehn C,Raffler J,Ried JS,Römisch-Margl W,Samani NJ,Small KS,Wichmann HE,Zhai G,Illig T,Spector TD,Adamski J,Soranzo N,Gieger C


 
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