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GSX1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol GSX1
Entrez Gene ID 219409
Full Name GS homeobox 1
Synonyms GSH1,Gsh-1
General protein information
Preferred Names

GS homeobox 1

Names

GS homeobox 1
GS homeo box protein 1
genomic screened homeo box 1
homeobox protein Gsh-1

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

13

13q12.2

Disorder MIM:

616542


mRNA and Protein(s)

mRNA Protein Name
NM_145657.2 NP_663632.1 GS homeobox 1



Mus musculus (house mouse) Gsx1 NP_032204.1
Xenopus tropicalis (tropical clawed frog) gsx1 NP_001039254.1
Macaca mulatta (rhesus monkey) GSX1 XP_001096656.2
Pan troglodytes (chimpanzee) GSX1 XP_522643.3
Bos taurus (cattle) GSX1 NP_001098918.1
Homo sapiens (human) GSX1 NP_663632.1
Rattus norvegicus (Norway rat) Gsx1 NP_001178592.1
Canis lupus familiaris (dog) GSX1 XP_003639921.1
Danio rerio (zebrafish) gsx1 NP_001012251.1


Related articles in PubMed

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Wolpin BM, Rizzato C, Kraft P, Kooperberg C, Petersen GM, Wang Z, Arslan AA, Beane-Freeman L, Bracci PM, Buring J, Canzian F, Duell EJ, Gallinger S, Giles GG, Goodman GE, Goodman PJ, Jacobs EJ, Kamineni A, Klein AP, Kolonel LN, Kulke MH, Li D, Malats N, Olson SH, Risch HA, Sesso HD, Visvanathan K, White E, Zheng W, Abnet CC, Albanes D, Andreotti G, Austin MA, Barfield R, Basso D, Berndt SI, Boutron-Ruault MC, Brotzman M, Büchler MW, Bueno-de-Mesquita HB, Bugert P, Burdette L, Campa D, Caporaso NE, Capurso G, Chung C, Cotterchio M, Costello E, Elena J, Funel N, Gaziano JM, Giese NA, Giovannucci EL, Goggins M, Gorman MJ, Gross M, Haiman CA, Hassan M, Helzlsouer KJ, Henderson BE, Holly EA, Hu N, Hunter DJ, Innocenti F, Jenab M, Kaaks R, Key TJ, Khaw KT, Klein EA, Kogevinas M, Krogh V, Kupcinskas J, Kurtz RC, LaCroix A, Landi MT, Landi S, Le Marchand L, Mambrini A, Mannisto S, Milne RL, Nakamura Y, Oberg AL, Owzar K, Patel AV, Peeters PH, Peters U, Pezzilli R, Piepoli A, Porta M, Real FX, Riboli E, Rothman N, Scarpa A, Shu XO, Silverman DT, Soucek P, Sund M, Talar-Wojnarowska R, Taylor PR, Theodoropoulos GE, Thornquist M, Tjønneland A, Tobias GS, Trichopoulos D, Vodicka P, Wactawski-Wende J, Wentzensen N, Wu C, Yu H, Yu K, Zeleniuch-Jacquotte A, Hoover R, Hartge P, Fuchs C, Chanock SJ, Stolzenberg-Solomon RS, Amundadottir LT
Nature genetics46(9)994-1000(2014 Sep)

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Low SK, Chung S, Takahashi A, Zembutsu H, Mushiroda T, Kubo M, Nakamura Y
Cancer science104(8)1074-82(2013 Aug)

Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.
Uzumcu A, Karaman B, Toksoy G, Uyguner ZO, Candan S, Eris H, Tatli B, Geckinli B, Yuksel A, Kayserili H, Basaran S
European journal of medical genetics52(5)315-20(2009 Sep-Oct)

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
Anney RJ, Lasky-Su J, O'Dúshláine C, Kenny E, Neale BM, Mulligan A, Franke B, Zhou K, Chen W, Christiansen H, Arias-Vásquez A, Banaschewski T, Buitelaar J, Ebstein R, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen H, Asherson P, Faraone SV, Gill M
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics147B(8)1369-78(2008 Dec)

The DNA sequence and analysis of human chromosome 13.
Dunham A, Matthews LH, Burton J, Ashurst JL, Howe KL, Ashcroft KJ, Beare DM, Burford DC, Hunt SE, Griffiths-Jones S, Jones MC, Keenan SJ, Oliver K, Scott CE, Ainscough R, Almeida JP, Ambrose KD, Andrews DT, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Bannerjee R, Barlow KF, Bates K, Beasley H, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burrill W, Carder C, Carter NP, Chapman JC, Clamp ME, Clark SY, Clarke G, Clee CM, Clegg SC, Cobley V, Collins JE, Corby N, Coville GJ, Deloukas P, Dhami P, Dunham I, Dunn M, Earthrowl ME, Ellington AG, Faulkner L, Frankish AG, Frankland J, French L, Garner P, Garnett J, Gilbert JG, Gilson CJ, Ghori J, Grafham DV, Gribble SM, Griffiths C, Hall RE, Hammond S, Harley JL, Hart EA, Heath PD, Howden PJ, Huckle EJ, Hunt PJ, Hunt AR, Johnson C, Johnson D, Kay M, Kimberley AM, King A, Laird GK, Langford CJ, Lawlor S, Leongamornlert DA, Lloyd DM, Lloyd C, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, McLaren SJ, McMurray A, Milne S, Moore MJ, Nickerson T, Palmer SA, Pearce AV, Peck AI, Pelan S, Phillimore B, Porter KM, Rice CM, Searle S, Sehra HK, Shownkeen R, Skuce CD, Smith M, Steward CA, Sycamore N, Tester J, Thomas DW, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Wilming L, Wray PW, Wright MW, Young L, Coulson A, Durbin R, Hubbard T, Sulston JE, Beck S, Bentley DR, Rogers J, Ross MT
Nature428(6982)522-8(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the study ruled out microdeletions on the critical region as a common cause of Moebius syndrome and excluded GSH1 gene
Title: Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.

The following GSX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GSX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu77884
NM_145657.2
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Homo sapiens GS homeobox 1 (GSX1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
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$199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu77884
Clone ID Related Accession (Same CDS sequence) NM_145657.2
Accession Version NM_145657.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 795bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-09-04
Organism Homo sapiens(Human)
Product GS homeobox 1
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB044157.1 and AL390738.4. On Dec 18, 2014 this sequence version replaced NM_145657.1. ##Evidence-Data-START## Transcript exon combination :: AB044157.1 [ECO:0000332] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_663632.1
CDS49..843
Misc Feature(1)49..108
Misc Feature(2)order(490..504,508..510,559..561,577..579,616..618,622..627,634..639,643..651,655..660)
Misc Feature(3)order(496..498,505..507,625..627,634..639,646..648)
Misc Feature(4)499..657
Exon (1)1..460
Exon (2)461..847
Translation

Target ORF information:

RefSeq Version NM_145657.2
Organism Homo sapiens(Human)
Definition Homo sapiens GS homeobox 1 (GSX1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_145657.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Nature genetics46(9)994-1000(2014 Sep)
Wolpin BM,Rizzato C,Kraft P,Kooperberg C,Petersen GM,Wang Z,Arslan AA,Beane-Freeman L,Bracci PM,Buring J,Canzian F,Duell EJ,Gallinger S,Giles GG,Goodman GE,Goodman PJ,Jacobs EJ,Kamineni A,Klein AP,Kolonel LN,Kulke MH,Li D,Malats N,Olson SH,Risch HA,Sesso HD,Visvanathan K,White E,Zheng W,Abnet CC,Albanes D,Andreotti G,Austin MA,Barfield R,Basso D,Berndt SI,Boutron-Ruault MC,Brotzman M,Büchler MW,Bueno-de-Mesquita HB,Bugert P,Burdette L,Campa D,Caporaso NE,Capurso G,Chung C,Cotterchio M,Costello E,Elena J,Funel N,Gaziano JM,Giese NA,Giovannucci EL,Goggins M,Gorman MJ,Gross M,Haiman CA,Hassan M,Helzlsouer KJ,Henderson BE,Holly EA,Hu N,Hunter DJ,Innocenti F,Jenab M,Kaaks R,Key TJ,Khaw KT,Klein EA,Kogevinas M,Krogh V,Kupcinskas J,Kurtz RC,LaCroix A,Landi MT,Landi S,Le Marchand L,Mambrini A,Mannisto S,Milne RL,Nakamura Y,Oberg AL,Owzar K,Patel AV,Peeters PH,Peters U,Pezzilli R,Piepoli A,Porta M,Real FX,Riboli E,Rothman N,Scarpa A,Shu XO,Silverman DT,Soucek P,Sund M,Talar-Wojnarowska R,Taylor PR,Theodoropoulos GE,Thornquist M,Tjønneland A,Tobias GS,Trichopoulos D,Vodicka P,Wactawski-Wende J,Wentzensen N,Wu C,Yu H,Yu K,Zeleniuch-Jacquotte A,Hoover R,Hartge P,Fuchs C,Chanock SJ,Stolzenberg-Solomon RS,Amundadottir LT


book

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Cancer science104(8)1074-82(2013 Aug)
Low SK,Chung S,Takahashi A,Zembutsu H,Mushiroda T,Kubo M,Nakamura Y


book

Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.
European journal of medical genetics52(5)315-20(2009 Sep-Oct)
Uzumcu A,Karaman B,Toksoy G,Uyguner ZO,Candan S,Eris H,Tatli B,Geckinli B,Yuksel A,Kayserili H,Basaran S


book

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics147B(8)1369-78(2008 Dec)
Anney RJ,Lasky-Su J,O'Dúshláine C,Kenny E,Neale BM,Mulligan A,Franke B,Zhou K,Chen W,Christiansen H,Arias-Vásquez A,Banaschewski T,Buitelaar J,Ebstein R,Miranda A,Mulas F,Oades RD,Roeyers H,Rothenberger A,Sergeant J,Sonuga-Barke E,Steinhausen H,Asherson P,Faraone SV,Gill M


book

The DNA sequence and analysis of human chromosome 13.
Nature428(6982)522-8(2004 Apr)
Dunham A,Matthews LH,Burton J,Ashurst JL,Howe KL,Ashcroft KJ,Beare DM,Burford DC,Hunt SE,Griffiths-Jones S,Jones MC,Keenan SJ,Oliver K,Scott CE,Ainscough R,Almeida JP,Ambrose KD,Andrews DT,Ashwell RI,Babbage AK,Bagguley CL,Bailey J,Bannerjee R,Barlow KF,Bates K,Beasley H,Bird CP,Bray-Allen S,Brown AJ,Brown JY,Burrill W,Carder C,Carter NP,Chapman JC,Clamp ME,Clark SY,Clarke G,Clee CM,Clegg SC,Cobley V,Collins JE,Corby N,Coville GJ,Deloukas P,Dhami P,Dunham I,Dunn M,Earthrowl ME,Ellington AG,Faulkner L,Frankish AG,Frankland J,French L,Garner P,Garnett J,Gilbert JG,Gilson CJ,Ghori J,Grafham DV,Gribble SM,Griffiths C,Hall RE,Hammond S,Harley JL,Hart EA,Heath PD,Howden PJ,Huckle EJ,Hunt PJ,Hunt AR,Johnson C,Johnson D,Kay M,Kimberley AM,King A,Laird GK,Langford CJ,Lawlor S,Leongamornlert DA,Lloyd DM,Lloyd C,Loveland JE,Lovell J,Martin S,Mashreghi-Mohammadi M,McLaren SJ,McMurray A,Milne S,Moore MJ,Nickerson T,Palmer SA,Pearce AV,Peck AI,Pelan S,Phillimore B,Porter KM,Rice CM,Searle S,Sehra HK,Shownkeen R,Skuce CD,Smith M,Steward CA,Sycamore N,Tester J,Thomas DW,Tracey A,Tromans A,Tubby B,Wall M,Wallis JM,West AP,Whitehead SL,Willey DL,Wilming L,Wray PW,Wright MW,Young L,Coulson A,Durbin R,Hubbard T,Sulston JE,Beck S,Bentley DR,Rogers J,Ross MT


 
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