Gene Symbol | C6orf136 |
Entrez Gene ID | 221545 |
Full Name | chromosome 6 open reading frame 136 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » C6orf136 cDNA ORF clone
Gene Symbol | C6orf136 |
Entrez Gene ID | 221545 |
Full Name | chromosome 6 open reading frame 136 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011514384.1 | XP_011512686.1 | uncharacterized protein C6orf136 isoform X1 |
NM_145029.3 | NP_659466.2 | uncharacterized protein C6orf136 isoform 2 |
NM_001161376.2 | NP_001154848.1 | uncharacterized protein C6orf136 isoform 3 |
NM_001109938.3 | NP_001103408.1 | uncharacterized protein C6orf136 isoform 1 |
NM_145029.4 | NP_659466.2 | uncharacterized protein C6orf136 isoform 2 |
NM_001109938.2 | NP_001103408.1 | uncharacterized protein C6orf136 isoform 1 |
NM_001161376.1 | NP_001154848.1 | uncharacterized protein C6orf136 isoform 3 |
XM_011514384.2 | XP_011512686.1 | uncharacterized protein C6orf136 isoform X1 |
Canis lupus familiaris (dog) | C12H6orf136 | XP_532058.3 |
Mus musculus (house mouse) | 2310061I04Rik | NP_001028802.1 |
C4H6orf136 | NP_001098633.1 | |
Xenopus tropicalis (tropical clawed frog) | c6orf136 | NP_001011197.2 |
Homo sapiens (human) | C6orf136 | NP_001103408.1 |
Pan troglodytes (chimpanzee) | C6H6orf136 | XP_527334.3 |
Bos taurus (cattle) | C23H6orf136 | NP_001033267.1 |
Rattus norvegicus (Norway rat) | RGD1302996 | NP_998775.2 |
FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.
Teh MT, Gemenetzidis E, Patel D, Tariq R, Nadir A, Bahta AW, Waseem A, Hutchison IL
PloS one7(3)e34329(2012)
The DNA sequence and analysis of human chromosome 6.
Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S
Nature425(6960)805-11(2003 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
C6orf136 was found to be differentially methylated and differentially expressed in human squamous cell carcinomas
Title: FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.
The following C6orf136 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C6orf136 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu78051 | |
Clone ID Related Accession (Same CDS sequence) | XM_011514384.1 , XM_011514384.2 | |
Accession Version | XM_011514384.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGAAC ATCTGTCTGT CATGTATGAG AGACTGAGAC AAGAGCTTCC CAAGCTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011512686.1 |
CDS | 715..1233 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011514384.1 |
1 | ATGGAGGAAC ATCTGTCTGT CATGTATGAG AGACTGAGAC AAGAGCTTCC CAAGCTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu78051 | |
Clone ID Related Accession (Same CDS sequence) | XM_011514384.1 , XM_011514384.2 | |
Accession Version | XM_011514384.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011514384.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGAAC ATCTGTCTGT CATGTATGAG AGACTGAGAC AAGAGCTTCC CAAGCTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011512686.1 |
CDS | 768..1286 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011514384.2 |
1 | ATGGAGGAAC ATCTGTCTGT CATGTATGAG AGACTGAGAC AAGAGCTTCC CAAGCTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu16350 | |
Clone ID Related Accession (Same CDS sequence) | NM_145029.3 , NM_145029.4 | |
Accession Version | NM_145029.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-23 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP255323.1, BM695485.1, BQ022831.1 and AI536982.1. On May 29, 2009 this sequence version replaced NM_145029.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BM695485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146411, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_659466.2 |
CDS | 194..739 |
Translation |
Target ORF information:
Target ORF information:
|
NM_145029.3 |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu16350 | |
Clone ID Related Accession (Same CDS sequence) | NM_145029.3 , NM_145029.4 | |
Accession Version | NM_145029.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP255323.1, BM695485.1 and BQ022831.1. On May 31, 2019 this sequence version replaced NM_145029.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BM695485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146411, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_659466.2 |
CDS | 100..645 |
Translation |
Target ORF information:
Target ORF information:
|
NM_145029.4 |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu16351 | |
Clone ID Related Accession (Same CDS sequence) | NM_001161376.2 , NM_001161376.1 | |
Accession Version | NM_001161376.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-30 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA200997.1, BC064397.1 and AI536982.1. On Nov 22, 2018 this sequence version replaced NM_001161376.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (3) that is longer than isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.260522.1, BC064397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000651131.1/ ENSP00000499201.1 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001154848.1 |
CDS | 100..1590 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001161376.2 |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu16351 | |
Clone ID Related Accession (Same CDS sequence) | NM_001161376.2 , NM_001161376.1 | |
Accession Version | NM_001161376.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA200997.1, BC064397.1 and AI536982.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (3) that is longer than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC064397.1, SRR1163657.426435.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001154848.1 |
CDS | 194..1684 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001161376.1 |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu16352 | |
Clone ID Related Accession (Same CDS sequence) | NM_001109938.3 , NM_001109938.2 | |
Accession Version | NM_001109938.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-31 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC073975.1 and AI536982.1. On Jun 1, 2019 this sequence version replaced NM_001109938.2. Transcript Variant: This variant (1) encodes isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.259754.1, SRR1163657.26368.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001103408.1 |
CDS | 100..1047 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001109938.3 |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu16352 | |
Clone ID Related Accession (Same CDS sequence) | NM_001109938.3 , NM_001109938.2 | |
Accession Version | NM_001109938.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-23 | |
Organism | Homo sapiens(human) | |
Product | uncharacterized protein C6orf136 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP255323.1, BC073975.1 and AI536982.1. On May 29, 2009 this sequence version replaced NM_001109938.1. Transcript Variant: This variant (1) encodes isoform 1. ##Evidence-Data-START## Transcript exon combination :: ERR279845.2088.1, BC073975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001103408.1 |
CDS | 194..1141 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001109938.2 |
1 | ATGTACCAGC CCAGCCGGGG TGCGGCCCGG CGTCTCGGCC CTTGCCTGCG CGCCTACCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma. |
The DNA sequence and analysis of human chromosome 6. |