Gene Symbol | GPC2 |
Entrez Gene ID | 221914 |
Full Name | glypican 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » GPC2 cDNA ORF clone
Gene Symbol | GPC2 |
Entrez Gene ID | 221914 |
Full Name | glypican 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_152742.2 | NP_689955.1 | glypican-2 precursor |
NM_152742.3 | NP_689955.1 | glypican-2 precursor |
EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.
Bouguenina H, Salaun D, Mangon A, Muller L, Baudelet E, Camoin L, Tachibana T, Cianf?rani S, Audebert S, Verdier-Pinard P, Badache A
Proceedings of the National Academy of Sciences of the United States of America114(50)E10687-E10696(2017 Dec)
Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.
Bosse KR, Raman P, Zhu Z, Lane M, Martinez D, Heitzeneder S, Rathi KS, Kendsersky NM, Randall M, Donovan L, Morrissy S, Sussman RT, Zhelev DV, Feng Y, Wang Y, Hwang J, Lopez G, Harenza JL, Wei JS, Pawel B, Bhatti T, Santi M, Ganguly A, Khan J, Marra MA, Taylor MD, Dimitrov DS, Mackall CL, Maris JM
Cancer cell32(3)295-309.e12(2017 Sep)
Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis.
Lugert S, Kremer T, Jagasia R, Herrmann A, Aigner S, Giachino C, Mendez-David I, Gardier AM, Carralot JP, Meistermann H, Augustin A, Saxe MD, Lamerz J, Duran-Pacheco G, Ducret A, Taylor V, David DJ, Czech C
Scientific reports746543(2017 Apr)
Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S
EMBO reports1(3)287-92(2000 Sep)
Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation.
Stipp CS, Litwack ED, Lander AD
The Journal of cell biology124(1-2)149-60(1994 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
these findings validate GPC2 as a non-mutated neuroblastoma oncoprotein and candidate immunotherapeutic target.
Title: Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.
The following GPC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu06908 | |
Clone ID Related Accession (Same CDS sequence) | NM_152742.2 , NM_152742.3 | |
Accession Version | NM_152742.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-02 | |
Organism | Homo sapiens(human) | |
Product | glypican-2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY045249.1, BC027972.1, AK096281.1 and AI863264.1. On Jan 13, 2015 this sequence version replaced NM_152742.1. ##Evidence-Data-START## Transcript exon combination :: BC027972.1, AK096281.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCGCGC TGCGACCTCT CCTGCTTCTG CTGCTGCCTC TGTGTCCCGG TCCTGGTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_689955.1 |
CDS | 228..1967 |
Translation |
Target ORF information:
Target ORF information:
|
NM_152742.2 |
1 | ATGTCCGCGC TGCGACCTCT CCTGCTTCTG CTGCTGCCTC TGTGTCCCGG TCCTGGTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06908 | |
Clone ID Related Accession (Same CDS sequence) | NM_152742.2 , NM_152742.3 | |
Accession Version | NM_152742.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-22 | |
Organism | Homo sapiens(human) | |
Product | glypican-2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY045249.1, BC027972.1, AK096281.1 and AI863264.1. On Nov 22, 2018 this sequence version replaced NM_152742.2. ##Evidence-Data-START## Transcript exon combination :: BC027972.1, AK096281.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000292377.4/ ENSP00000292377.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGTCCGCGC TGCGACCTCT CCTGCTTCTG CTGCTGCCTC TGTGTCCCGG TCCTGGTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_689955.1 |
CDS | 183..1922 |
Translation |
Target ORF information:
Target ORF information:
|
NM_152742.3 |
1 | ATGTCCGCGC TGCGACCTCT CCTGCTTCTG CTGCTGCCTC TGTGTCCCGG TCCTGGTCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions. |
Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma. |
Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis. |
Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |
Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation. |