Gene Symbol | PSME4 |
Entrez Gene ID | 23198 |
Full Name | proteasome activator subunit 4 |
Synonyms | PA200 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » PSME4 cDNA ORF clone
Gene Symbol | PSME4 |
Entrez Gene ID | 23198 |
Full Name | proteasome activator subunit 4 |
Synonyms | PA200 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_006711969.1 | XP_006712032.1 | proteasome activator complex subunit 4 isoform X5 |
NM_014614.3 | NP_055429.2 | proteasome activator complex subunit 4 |
XM_011532705.2 | XP_011531007.1 | proteasome activator complex subunit 4 isoform X1 |
XM_011532706.2 | XP_011531008.1 | proteasome activator complex subunit 4 isoform X2 |
NM_014614.2 | NP_055429.2 | proteasome activator complex subunit 4 |
XM_011532707.2 | XP_011531009.1 | proteasome activator complex subunit 4 isoform X3 |
XM_011532709.2 | XP_011531011.1 | proteasome activator complex subunit 4 isoform X4 |
Homo sapiens (human) | PSME4 | NP_055429.2 |
LOC716580 | XP_002808086.1 | |
Rattus norvegicus (Norway rat) | Psme4 | NP_001020311.2 |
Danio rerio (zebrafish) | LOC100535277 | XP_005157069.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002597 | XP_312339.5 |
Pan troglodytes (chimpanzee) | PSME4 | XP_003309060.1 |
Bos taurus (cattle) | PSME4 | NP_001192881.1 |
Caenorhabditis elegans (roundworm) | C14C10.5 | NP_506153.1 |
Xenopus tropicalis (tropical clawed frog) | psme4 | XP_002936960.1 |
Canis lupus familiaris (dog) | PSME4 | XP_005626163.1 |
Mus musculus (house mouse) | Psme4 | NP_598774.2 |
Gallus gallus (chicken) | PSME4 | NP_001006393.2 |
Danio rerio (zebrafish) | psme4b | NP_001177949.1 |
Danio rerio (zebrafish) | psme4a | XP_005157072.1 |
Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.
Oshikawa M, Tsutsui C, Ikegami T, Fuchida Y, Matsubara M, Toyama S, Usami R, Ohtoko K, Kato S
Investigative ophthalmology & visual science52(9)6662-70(2011 Aug)
Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)
Proteasomes and proteasome activator 200 kDa (PA200) accumulate on chromatin in response to ionizing radiation.
Blickwedehl J, McEvoy S, Wong I, Kousis P, Clements J, Elliott R, Cresswell P, Liang P, Bangia N
Radiation research167(6)663-74(2007 Jun)
Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.
Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK
Developmental cell4(6)813-26(2003 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
identified a novel 200 kDa nuclear protein that activates the proteasome; findings implicate PA200 in DNA repair, possibly by recruiting proteasomes to double strand breaks
Title: PA200, a nuclear proteasome activator involved in DNA repair.
The following PSME4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PSME4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu06580 | |
Clone ID Related Accession (Same CDS sequence) | NM_014614.3 , NM_014614.2 | |
Accession Version | NM_014614.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5532bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-16 | |
Organism | Homo sapiens(human) | |
Product | proteasome activator complex subunit 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC008068.4, AY894754.1, BC113668.1, AA884260.1 and AL045471.1. On Nov 22, 2018 this sequence version replaced NM_014614.2. ##Evidence-Data-START## Transcript exon combination :: D38521.1, SRR1803616.98764.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000404125.6/ ENSP00000384211.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_055429.2 |
CDS | 210..5741 |
Translation |
Target ORF information:
Target ORF information:
|
NM_014614.3 |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06580 | |
Clone ID Related Accession (Same CDS sequence) | NM_014614.3 , NM_014614.2 | |
Accession Version | NM_014614.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5532bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | proteasome activator complex subunit 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY894754.1, BC113668.1, AA884260.1 and AL045471.1. On Dec 20, 2007 this sequence version replaced NM_014614.1. ##Evidence-Data-START## Transcript exon combination :: D38521.1, SRR1803616.98764.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_055429.2 |
CDS | 57..5588 |
Translation |
Target ORF information:
Target ORF information:
|
NM_014614.2 |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu35329 | |
Clone ID Related Accession (Same CDS sequence) | XM_006711969.1 | |
Accession Version | XM_006711969.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3006bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome activator complex subunit 4 isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGTCCT TGGAAGAGAC AAAGTTGTAT ACTGGACTTG AATATGATCT GTCTCGAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006712032.1 |
CDS | 2160..5165 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006711969.1 |
1 | ATGGTGTCCT TGGAAGAGAC AAAGTTGTAT ACTGGACTTG AATATGATCT GTCTCGAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu65685 | |
Clone ID Related Accession (Same CDS sequence) | XM_011532705.2 | |
Accession Version | XM_011532705.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5610bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome activator complex subunit 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532705.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011531007.1 |
CDS | 15..5624 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011532705.2 |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu65686 | |
Clone ID Related Accession (Same CDS sequence) | XM_011532706.2 | |
Accession Version | XM_011532706.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5598bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome activator complex subunit 4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532706.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011531008.1 |
CDS | 15..5612 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011532706.2 |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu65687 | |
Clone ID Related Accession (Same CDS sequence) | XM_011532707.2 | |
Accession Version | XM_011532707.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5544bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome activator complex subunit 4 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532707.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011531009.1 |
CDS | 15..5558 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011532707.2 |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu65689 | |
Clone ID Related Accession (Same CDS sequence) | XM_011532709.2 | |
Accession Version | XM_011532709.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome activator complex subunit 4 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532709.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011531011.1 |
CDS | 15..3374 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011532709.2 |
1 | ATGGAGCCGG CCGAGCGGGC GGGAGTCGGA GAGCCCCCGG AGCCGGGCGG GCGTCCCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. |
Proteomic characterization of the human sperm nucleus. |
Proteasomes and proteasome activator 200 kDa (PA200) accumulate on chromatin in response to ionizing radiation. |
Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. |