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SCRIB cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol SCRIB
Entrez Gene ID 23513
Full Name scribbled planar cell polarity protein
Synonyms CRIB1,SCRB1,SCRIB1,Vartul
General protein information
Preferred Names

scribbled planar cell polarity protein

Names

protein scribble homolog
scribbled homolog
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

8

8q24.3
Summary This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Disorder MIM:

607733


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_182706.5 NP_874365.3 protein scribble homolog isoform a
NM_015356.4 NP_056171.3 protein scribble homolog isoform b
NM_015356.5 NP_056171.3 protein scribble homolog isoform b
NM_182706.4 NP_874365.3 protein scribble homolog isoform a

Pathways from BioSystems


Homologies


Bos taurus (cattle) SCRIB XP_003586927.1
Mus musculus (house mouse) Scrib NP_598850.1
Danio rerio (zebrafish) scrib NP_001007176.1
Xenopus tropicalis (tropical clawed frog) scrib NP_001243220.1
Pan troglodytes (chimpanzee) SCRIB XP_003951409.1
Caenorhabditis elegans (roundworm) let-413 NP_001023851.1
Homo sapiens (human) SCRIB NP_874365.3
Canis lupus familiaris (dog) SCRIB XP_005628363.1
Rattus norvegicus (Norway rat) Scrib NP_001178808.1

Gene Ontology


Bibliography

Related articles in PubMed

The Sign of Nuclear Magnetic Resonance Chemical Shift Difference as a Determinant of the Origin of Binding Selectivity: Elucidation of the Position Dependence of Phosphorylation in Ligands Binding to Scribble PDZ1.
Sundell GN, V?geli B, Ivarsson Y, Chi CN
Biochemistry57(1)66-71(2018 Jan)

Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor.
Khalil S, Delehanty L, Grado S, Holy M, White Z 3rd, Freeman K, Kurita R, Nakamura Y, Bullock G, Goldfarb A
The Journal of experimental medicine(2017 Dec)

Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness.
Wan S, Meyer AS, Weiler SME, Rupp C, T?th M, Sticht C, Singer S, Thomann S, Roessler S, Schorpp-Kistner M, Schmitt J, Gretz N, Angel P, Tschaharganeh DF, Marquardt J, Schirmacher P, Pinna F, Breuhahn K
Hepatology (Baltimore, Md.)(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

sequencing analysis of SCRIB1 in 473 NTD patients led to the identification of 5 rare heterozygous missense mutations that were predicted to be pathogenic. Two of these mutations, p.Gly263Ser and p.Gln808His, and 2 mouse NTD mutations, p.Ile285Lys and p.Glu814Gly, affected Scrib1 membrane localization and its modulating role of Par-3 and Vangl1 localization.
Title: Scribble1 plays an important role in the pathogenesis of neural tube defects through its mediating effect of Par-3 and Vangl1/2 localization.

Low Scribble expression in the primary breast tumor was correlated to prognosis in estrogen receptor-positive breast cancer patients.
Title: Expression of cell polarity protein scribble differently affects prognosis in primary tumor and lymph node metastasis of breast cancer patients.

Suggest a role for Plexin-B1 as a ligand and Sema4A as a receptor and characterize a reverse signaling pathway downstream of Sema4A regulating cell migration via Scrib.
Title: A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.

inhibiting acyl thioesterase 2 restores balance to the Scrib palmitoylation cycle, promoting membrane re-localization and growth attenuation
Title: APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells.

SCRIB uncouples reactive oxygen species-dependent bacterial killing activity from M1 polarization and inflammatory functions of macrophages
Title: An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function.

The following SCRIB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCRIB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu107527 NM_182706.5
Latest version!		 Homo sapiens scribble planar cell polarity protein (SCRIB), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 24-26 $811.30
$1159.00
OHu108226 NM_015356.5
Latest version!		 Homo sapiens scribble planar cell polarity protein (SCRIB), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 24-26 $811.30
$1159.00
OHu27016 NM_182706.4
Latest version!		 Homo sapiens scribbled planar cell polarity protein (SCRIB), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $923.30
$1319.00
OHu27147 NM_015356.4
Latest version!		 Homo sapiens scribble planar cell polarity protein (SCRIB), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $923.30
$1319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone 40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu107527
Clone ID Related Accession (Same CDS sequence) NM_182706.5
Accession Version NM_182706.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4968bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-15
Organism Homo sapiens(human)
Product protein scribble homolog isoform a
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC105219.6 and KF458881.1. On Nov 23, 2018 this sequence version replaced NM_182706.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000356994.7/ ENSP00000349486.2 RefSeq Select criteria :: based on manual assertion, conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACCGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACT ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTTGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCA CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGCCCTT GTCTGGAAAG AAGTTTGACT ACAGGGCCTT TGCGGCCCTG 
CCTTCTTCCA GACCTGTCTA TGACATCCAG TCACCGGACT TTGCTGAGGA GTTGAGGTCC 
CTGGAACCAT CTCCCAGCCC TGGCCCGCAG GAGGAGGATG GAGAAGTGGC TCTGGTGCTT 
CTGGGCAGGC CCTCACCCGG CGCTGTGGGC CCTGAAGATG TGGCACTGTG CAGCAGCCGC 
CGCCCCGTAA GGCCTGGGCG CCGTGGCCTG GGCCCTGTGC CCTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_874365.3
CDS402..5369
Translation

Target ORF information:

RefSeq Version NM_182706.5
Organism Homo sapiens(human)
Definition Homo sapiens scribble planar cell polarity protein (SCRIB), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_182706.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACCGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACT ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTTGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCA CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGCCCTT GTCTGGAAAG AAGTTTGACT ACAGGGCCTT TGCGGCCCTG 
CCTTCTTCCA GACCTGTCTA TGACATCCAG TCACCGGACT TTGCTGAGGA GTTGAGGTCC 
CTGGAACCAT CTCCCAGCCC TGGCCCGCAG GAGGAGGATG GAGAAGTGGC TCTGGTGCTT 
CTGGGCAGGC CCTCACCCGG CGCTGTGGGC CCTGAAGATG TGGCACTGTG CAGCAGCCGC 
CGCCCCGTAA GGCCTGGGCG CCGTGGCCTG GGCCCTGTGC CCTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu108226
Clone ID Related Accession (Same CDS sequence) NM_015356.5
Accession Version NM_015356.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4893bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-15
Organism Homo sapiens(human)
Product protein scribble homolog isoform b
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC105219.6 and KF458881.1. On May 31, 2019 this sequence version replaced NM_015356.4. Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY062238.1, AF240677.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACCGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACT ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTTGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCA CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGTCACC GGACTTTGCT GAGGAGTTGA GGTCCCTGGA ACCATCTCCC 
AGCCCTGGCC CGCAGGAGGA GGATGGAGAA GTGGCTCTGG TGCTTCTGGG CAGGCCCTCA 
CCCGGCGCTG TGGGCCCTGA AGATGTGGCA CTGTGCAGCA GCCGCCGCCC CGTAAGGCCT 
GGGCGCCGTG GCCTGGGCCC TGTGCCCTCC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_056171.3
CDS402..5294
Translation

Target ORF information:

RefSeq Version NM_015356.5
Organism Homo sapiens(human)
Definition Homo sapiens scribble planar cell polarity protein (SCRIB), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_015356.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACCGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACT ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTTGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCA CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGTCACC GGACTTTGCT GAGGAGTTGA GGTCCCTGGA ACCATCTCCC 
AGCCCTGGCC CGCAGGAGGA GGATGGAGAA GTGGCTCTGG TGCTTCTGGG CAGGCCCTCA 
CCCGGCGCTG TGGGCCCTGA AGATGTGGCA CTGTGCAGCA GCCGCCGCCC CGTAAGGCCT 
GGGCGCCGTG GCCTGGGCCC TGTGCCCTCC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27016
Clone ID Related Accession (Same CDS sequence) NM_182706.4
Accession Version NM_182706.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4968bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-11-11
Organism Homo sapiens(human)
Product protein scribble homolog isoform a
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY062238.1, AI829609.1, BC044627.1, BC009490.2 and BC014632.2. This sequence is a reference standard in the RefSeqGene project. On Nov 3, 2011 this sequence version replaced NM_182706.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACTGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACC ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTCGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCG CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGCCCTT GTCTGGAAAG AAGTTTGACT ACAGGGCCTT TGCGGCCCTG 
CCTTCTTCCA GACCTGTCTA TGACATCCAG TCACCGGACT TTGCTGAGGA GTTGAGGTCC 
CTGGAACCAT CTCCCAGCCC TGGCCCGCAG GAGGAGGATG GAGAAGTGGC TCTGGTGCTT 
CTGGGCAGGC CCTCACCCGG CGCTGTGGGC CCTGAAGATG TGGCACTGTG CAGCAGCCGC 
CGCCCCGTAA GGCCTGGGCG CCGTGGCCTG GGCCCTGTGC CCTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_874365.3
CDS8..4975
Translation

Target ORF information:

RefSeq Version NM_182706.4
Organism Homo sapiens(human)
Definition Homo sapiens scribbled planar cell polarity protein (SCRIB), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_182706.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACTGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACC ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTCGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCG CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGCCCTT GTCTGGAAAG AAGTTTGACT ACAGGGCCTT TGCGGCCCTG 
CCTTCTTCCA GACCTGTCTA TGACATCCAG TCACCGGACT TTGCTGAGGA GTTGAGGTCC 
CTGGAACCAT CTCCCAGCCC TGGCCCGCAG GAGGAGGATG GAGAAGTGGC TCTGGTGCTT 
CTGGGCAGGC CCTCACCCGG CGCTGTGGGC CCTGAAGATG TGGCACTGTG CAGCAGCCGC 
CGCCCCGTAA GGCCTGGGCG CCGTGGCCTG GGCCCTGTGC CCTCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27147
Clone ID Related Accession (Same CDS sequence) NM_015356.4
Accession Version NM_015356.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4893bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-22
Organism Homo sapiens(human)
Product protein scribble homolog isoform b
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY062238.1, AI829609.1, AF240677.1 and BC014632.2. On Nov 3, 2011 this sequence version replaced NM_015356.3. Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY062238.1, D63481.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACTGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACC ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTCGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCG CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGTCACC GGACTTTGCT GAGGAGTTGA GGTCCCTGGA ACCATCTCCC 
AGCCCTGGCC CGCAGGAGGA GGATGGAGAA GTGGCTCTGG TGCTTCTGGG CAGGCCCTCA 
CCCGGCGCTG TGGGCCCTGA AGATGTGGCA CTGTGCAGCA GCCGCCGCCC CGTAAGGCCT 
GGGCGCCGTG GCCTGGGCCC TGTGCCCTCC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_056171.3
CDS8..4900
Translation

Target ORF information:

RefSeq Version NM_015356.4
Organism Homo sapiens(human)
Definition Homo sapiens scribble planar cell polarity protein (SCRIB), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_015356.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
ATGCTCAAGT GCATCCCGCT GTGGCGCTGC AACCGGCACG TGGAGTCGGT GGACAAGCGG 
CACTGTTCGC TGCAGGCCGT GCCGGAGGAG ATCTACCGCT ACAGCCGCAG CCTGGAGGAG 
CTGCTGCTCG ACGCCAACCA GCTGCGCGAG CTGCCCAAGC CTTTTTTCCG GCTGCTGAAC 
TTGCGCAAGC TGGGCCTGAG CGACAACGAG ATCCAGCGGT TGCCTCCCGA GGTGGCCAAC 
TTCATGCAGC TGGTGGAGCT GGACGTGTCC CGGAACGATA TCCCTGAGAT CCCGGAGAGC 
ATCAAGTTCT GCAAGGCTCT GGAGATCGCG GACTTCAGCG GGAACCCCCT CTCCAGGCTC 
CCTGATGGCT TCACTCAGCT GCGCAGCCTG GCTCACCTGG CCCTGAATGA TGTGTCTCTG 
CAGGCACTGC CCGGGGACGT GGGCAACCTC GCCAACCTGG TGACCCTGGA GCTCCGGGAG 
AACCTGCTCA AGTCCCTGCC AGCGTCCCTG TCATTTCTGG TCAAGCTGGA ACAGCTGGAT 
CTGGGAGGCA ACGATCTGGA AGTGCTGCCA GACACTCTGG GGGCTCTGCC CAATCTTCGG 
GAGCTGTGGC TTGACCGGAA CCAGCTGTCA GCACTGCCCC CGGAGCTCGG GAACCTGCGG 
CGCCTGGTGT GCCTGGACGT GTCGGAAAAC CGGCTGGAGG AGCTGCCTGC TGAGCTCGGC 
GGGCTGGTGC TGCTCACTGA CCTGCTGCTG TCCCAGAACC TGCTGCGGAG GCTGCCCGAC 
GGCATCGGTC AGCTGAAGCA GCTATCCATC CTAAAGGTAG ACCAGAATCG GCTGTGCGAG 
GTGACTGAGG CCATCGGGGA CTGTGAGAAC CTCTCTGAGC TGATCCTCAC GGAGAACCTG 
CTGATGGCCC TGCCCCGCTC CCTGGGAAAG CTGACTAAGC TGACCAACCT CAACGTGGAC 
CGGAACCACC TCGAGGCGCT GCCGCCCGAG ATCGGGGGCT GTGTGGCACT CAGCGTCCTC 
TCCTTGAGGG ACAACCGCCT GGCCGTCCTG CCACCAGAGC TGGCCCACAC GACAGAGCTG 
CACGTGCTGG ACGTGGCGGG GAACCGCCTG CAGAGTCTGC CGTTCGCGCT CACCCACCTC 
AATCTCAAGG CCCTGTGGCT GGCAGAGAAC CAGGCGCAGC CCATGCTCCG GTTCCAGACG 
GAGGATGATG CCCGGACCGG CGAGAAGGTG CTCACCTGCT ACTTGCTGCC CCAGCAGCCC 
CCACCCAGCC TCGAGGATGC TGGGCAGCAG GGGAGCCTCT CGGAGACCTG GAGCGATGCC 
CCGCCGAGCC GCGTCAGCGT CATCCAGTTC CTGGAGGCCC CCATAGGTGA TGAGGACGCT 
GAGGAAGCTG CAGCTGAGAA GCGGGGCCTA CAGCGCCGGG CCACACCTCA CCCCAGCGAG 
CTCAAGGTGA TGAAGAGGAG CATCGAGGGG CGGCGGAGCG AGGCCTGCCC TTGCCAGCCA 
GACTCTGGGT CGCCCTTGCC TGCAGAGGAG GAGAAGCGGC TGAGTGCCGA GTCTGGCCTG 
AGTGAAGACT CTCGCCCATC TGCCAGCACA GTCTCTGAGG CTGAGCCCGA GGGCCCGTCG 
GCTGAGGCAC AGGGTGGGAG CCAGCAGGAA GCCACGACTG CTGGCGGGGA GGAAGACGCC 
GAAGAGGACT ACCAGGAGCC CACGGTGCAT TTCGCAGAGG ACGCACTGCT GCCCGGGGAT 
GACAGGGAGA TCGAGGAGGG GCAGCCTGAG GCCCCCTGGA CCCTGCCAGG CGGGAGGCAG 
CGGCTCATCC GCAAGGACAC ACCTCACTAC AAAAAGCACT TCAAGATCTC CAAGCTGCCC 
CAGCCCGAGG CCGTTGTGGC TCTGCTGCAG GGCATGCAGC CTGATGGGGA GGGCCCTGTG 
GCTCCCGGGG GCTGGCACAA TGGCCCCCAC GCACCCTGGG CTCCTCGGGC CCAGAAGGAG 
GAGGAGGAGG AGGAAGAGGG TAGTCCTCAG GAGGAGGAGG AAGAGGAGGA GGAGGAAAAC 
AGGGCTGAAG AGGAAGAGGC CAGCACTGAG GAGGAGGACA AGGAGGGGGC CGTGGTTTCT 
GCGCCCTCTG TCAAGGGAGT GTCGTTTGAC CAGGCCAATA ACCTGCTGAT AGAGCCTGCT 
CGCATTGAGG AGGAAGAGCT GACCCTCACC ATCCTGCGGC AGACTGGGGG CCTGGGCATC 
AGCATTGCGG GCGGCAAGGG CTCCACACCC TATAAGGGGG ACGACGAGGG CATATTCATC 
TCTCGGGTGT CCGAGGAAGG CCCTGCGGCC CGGGCTGGAG TCCGTGTGGG TGACAAGCTC 
CTGGAGGTGA ATGGTGTGGC TCTGCAGGGC GCCGAGCACC ACGAGGCCGT GGAGGCGCTC 
CGGGGGGCCG GCACTGCCGT GCAGATGCGA GTGTGGCGGG AGCGCATGGT GGAGCCTGAG 
AACGCGGTCA CCATCACGCC GCTGCGGCCC GAGGATGATT ACAGCCCCCG AGAGCGGCGG 
GGAGGGGGGC TGCGCCTGCC CCTGCTCCCG CCTGAGAGCC CCGGGCCCCT CCGTCAGCGC 
CACGTGGCCT GCCTGGCACG CAGCGAGAGG GGGCTGGGCT TCAGCATTGC TGGTGGGAAA 
GGCTCCACAC CCTACAGGGC TGGTGATGCG GGCATCTTCG TCTCCCGCAT TGCCGAGGGC 
GGTGCTGCTC ACCGCGCGGG CACACTGCAG GTTGGCGACC GCGTCCTCTC TATTAATGGA 
GTGGACGTGA CTGAGGCCAG GCATGACCAC GCCGTCTCCC TGCTGACCGC TGCCTCCCCC 
ACCATCGCCC TGCTGTTGGA GCGGGAGGCT GGGGGCCCTC TTCCTCCCAG CCCTCTGCCA 
CATTCCTCAC CCCCCACCGC TGCTGTTGCC ACCACCAGCA TAACCACTGC CACCCCCGGG 
GTGCCTGGGT TGCCGAGCCT GGCCCCCAGC CTGCTGGCTG CCGCGTTGGA AGGGCCATAC 
CCAGTGGAGG AGATCCGTCT GCCAAGAGCT GGGGGCCCTC TGGGGCTTAG TATTGTCGGA 
GGCTCCGACC ATTCCAGCCA CCCGTTTGGT GTCCAGGAGC CTGGTGTGTT CATCTCCAAG 
GTGCTCCCGC GGGGCCTGGC CGCTCGCAGC GGCCTGCGGG TTGGGGACCG CATCCTGGCA 
GTGAACGGGC AAGACGTGCG GGATGCCACG CACCAAGAAG CAGTCAGTGC CCTGCTCCGG 
CCCTGCCTGG AGCTGTCGCT GCTGGTGCGG AGGGACCCGG CACCCCCGGG CCTACGGGAA 
CTGTGCATCC AGAAGGCACC TGGGGAGAGG CTGGGCATCA GCATCCGCGG GGGTGCCAGG 
GGCCACGCTG GCAACCCCCG CGACCCCACA GACGAGGGCA TCTTCATCTC CAAGGTGAGC 
CCCACGGGGG CAGCCGGGCG CGACGGTCGG CTGCGTGTGG GTTTGCGGCT GTTGGAGGTG 
AACCAGCAGA GCCTGCTGGG CCTGACGCAC GGCGAGGCGG TGCAGCTGCT CCGCAGTGTG 
GGCGACACCC TCACCGTGCT GGTCTGTGAC GGCTTCGAGG CCAGCACCGA CGCAGCCCTG 
GAGGTGTCCC CAGGTGTCAT TGCCAACCCC TTTGCGGCAG GCATCGGCCA CCGGAACAGC 
CTGGAGAGCA TCTCTTCCAT CGACCGGGAG CTGAGCCCTG AGGGCCCAGG CAAGGAGAAG 
GAGCTGCCTG GACAGACCCT GCACTGGGGG CCCGAGGCCA CAGAAGCCGC AGGTCGGGGT 
CTGCAGCCCC TGAAGCTGGA CTACCGCGCC CTGGCCGCCG TGCCCAGCGC TGGCAGCGTG 
CAGAGGGTAC CGTCTGGAGC AGCTGGAGGG AAGATGGCTG AATCTCCCTG CTCCCCTAGT 
GGCCAGCAGC CGCCCTCCCC GCCTTCTCCG GATGAGCTGC CCGCCAATGT GAAGCAGGCC 
TACAGGGCCT TCGCGGCCGT GCCCACTTCT CACCCGCCTG AGGATGCCCC TGCCCAGCCC 
CCCACGCCTG GGCCTGCAGC CTCCCCGGAG CAGCTGTCCT TCCGGGAGCG GCAGAAGTAC 
TTTGAGCTGG AGGTGCGCGT GCCCCAGGCC GAGGGCCCCC CTAAGCGCGT GTCCCTGGTG 
GGTGCTGACG ACCTGCGGAA GATGCAGGAG GAGGAAGCCA GAAAACTACA GCAGAAGAGA 
GCGCAGATGC TGCGGGAGGC GGCAGAGGCT GGGGCCGAAG CGAGGCTCGC CCTGGACGGG 
GAGACGCTGG GCGAGGAGGA ACAGGAGGAT GAGCAGCCAC CCTGGGCCAG CCCGAGCCCC 
ACCTCAAGGC AGAGCCCGGC GTCCCCCCCG CCCCTGGGAG GTGGCGCCCC GGTGCGGACG 
GCCAAAGCTG AACGGCGCCA CCAGGAGCGG CTGCGCGTGC AGAGTCCGGA GCCACCGGCA 
CCCGAGCGTG CCCTGTCCCC TGCCGAGCTC CGGGCCCTGG AGGCCGAGAA GCGTGCGCTG 
TGGAGGGCAG CCAGGATGAA GTCATTGGAA CAGGACGCTC TCCGAGCACA GATGGTCCTC 
AGCAGGTCCC AGGAAGGCCG GGGCACGCGG GGGCCCCTGG AGCGACTGGC CGAGGCCCCT 
TCCCCTGCGC CCACCCCGTC GCCCACCCCT GTGGAAGACC TCGGCCCCCA GACCAGCACC 
TCCCCGGGAC GCCTGTCACC GGACTTTGCT GAGGAGTTGA GGTCCCTGGA ACCATCTCCC 
AGCCCTGGCC CGCAGGAGGA GGATGGAGAA GTGGCTCTGG TGCTTCTGGG CAGGCCCTCA 
CCCGGCGCTG TGGGCCCTGA AGATGTGGCA CTGTGCAGCA GCCGCCGCCC CGTAAGGCCT 
GGGCGCCGTG GCCTGGGCCC TGTGCCCTCC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

The Sign of Nuclear Magnetic Resonance Chemical Shift Difference as a Determinant of the Origin of Binding Selectivity: Elucidation of the Position Dependence of Phosphorylation in Ligands Binding to Scribble PDZ1.
Biochemistry57(1)66-71(2018 Jan)
Sundell GN,V?geli B,Ivarsson Y,Chi CN


book

Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor.
The Journal of experimental medicine(2017 Dec)
Khalil S,Delehanty L,Grado S,Holy M,White Z 3rd,Freeman K,Kurita R,Nakamura Y,Bullock G,Goldfarb A


book

Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness.
Hepatology (Baltimore, Md.)(2017 Nov)
Wan S,Meyer AS,Weiler SME,Rupp C,T?th M,Sticht C,Singer S,Thomann S,Roessler S,Schorpp-Kistner M,Schmitt J,Gretz N,Angel P,Tschaharganeh DF,Marquardt J,Schirmacher P,Pinna F,Breuhahn K