Gene Symbol | CNPY4 |
Entrez Gene ID | 245812 |
Full Name | canopy FGF signaling regulator 4 |
Synonyms | PRAT4B |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » CNPY4 cDNA ORF clone
gRNAs
Gene Symbol | CNPY4 |
Entrez Gene ID | 245812 |
Full Name | canopy FGF signaling regulator 4 |
Synonyms | PRAT4B |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_152755.1 | NP_689968.1 | protein canopy homolog 4 precursor |
NM_152755.2 | NP_689968.1 | protein canopy homolog 4 precursor |
Homo sapiens (human) | CNPY4 | NP_689968.1 |
Pan troglodytes (chimpanzee) | CNPY4 | XP_519249.2 |
Drosophila melanogaster (fruit fly) | CG11577 | NP_649089.2 |
CNPY4 | XP_001112702.2 | |
Bos taurus (cattle) | CNPY4 | NP_001029425.1 |
Rattus norvegicus (Norway rat) | Cnpy4 | NP_001102322.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011140 | XP_309508.3 |
Danio rerio (zebrafish) | cnpy4 | NP_001034602.1 |
Canis lupus familiaris (dog) | CNPY4 | XP_546963.2 |
Mus musculus (house mouse) | Cnpy4 | NP_848727.1 |
Cell surface trafficking of TLR1 is differentially regulated by the chaperones PRAT4A and PRAT4B.
Hart BE, Tapping RI
The Journal of biological chemistry287(20)16550-62(2012 May)
A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.
Konno K, Wakabayashi Y, Akashi-Takamura S, Ishii T, Kobayashi M, Takahashi K, Kusumoto Y, Saitoh S, Yoshizawa Y, Miyake K
Biochemical and biophysical research communications339(4)1076-82(2006 Jan)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a mechanism for the differential trafficking of TLR1 I602S variants, and highlight the distinct roles for PRAT4A and PRAT4B in the regulation of TLR1 surface expression.
Title: Cell surface trafficking of TLR1 is differentially regulated by the chaperones PRAT4A and PRAT4B.
A PRotein Associated with Tlr4 (PRAT4B), regulates cell surface expression of TLR4. PRAT4B has a signal peptide followed by a mature peptide. PRAT4B is associated with the hypoglycosylated, immature form of TLR4 but not with MD-2 or TLR2.
Title: A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.
The following CNPY4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CNPY4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu29774![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_152755.1 , NM_152755.2 | |
Accession Version | NM_152755.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Homo sapiens(human) | |
Product | protein canopy homolog 4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC032339.1. On or before Mar 4, 2006 this sequence version replaced XM_941945.1, XM_945568.1. ##Evidence-Data-START## Transcript exon combination :: BC032339.1, AY359100.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGACCTG TGCGGTTGGG AATATTGCTT TTCCTTTTTT TGGCCGTGCA CGAGGCTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_689968.1 |
CDS | 104..850 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGACCTG TGCGGTTGGG AATATTGCTT TTCCTTTTTT TGGCCGTGCA CGAGGCTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu29774![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_152755.1 , NM_152755.2 | |
Accession Version | NM_152755.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-01 | |
Organism | Homo sapiens(human) | |
Product | protein canopy homolog 4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC073842.5 and BC032339.1. On Nov 22, 2018 this sequence version replaced NM_152755.1. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.4587.1, SRR5189655.197117.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000262932.5/ ENSP00000262932.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGGACCTG TGCGGTTGGG AATATTGCTT TTCCTTTTTT TGGCCGTGCA CGAGGCTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_689968.1 |
CDS | 112..858 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGACCTG TGCGGTTGGG AATATTGCTT TTCCTTTTTT TGGCCGTGCA CGAGGCTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cell surface trafficking of TLR1 is differentially regulated by the chaperones PRAT4A and PRAT4B. |
A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression. |
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |