Gene Symbol | ANGPTL5 |
Entrez Gene ID | 253935 |
Full Name | angiopoietin like 5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » ANGPTL5 cDNA ORF clone
Gene Symbol | ANGPTL5 |
Entrez Gene ID | 253935 |
Full Name | angiopoietin like 5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_017017466.1 | XP_016872955.1 | angiopoietin-related protein 5 isoform X2 |
NM_178127.5 | NP_835228.2 | angiopoietin-related protein 5 precursor |
NM_178127.4 | NP_835228.2 | angiopoietin-related protein 5 precursor |
XM_017017466.2 | XP_016872955.1 | angiopoietin-related protein 5 isoform X2 |
XM_011542735.1 | XP_011541037.1 | angiopoietin-related protein 5 isoform X1 |
XM_011542735.3 | XP_011541037.1 | angiopoietin-related protein 5 isoform X1 |
XM_011542735.2 | XP_011541037.1 | angiopoietin-related protein 5 isoform X1 |
Homo sapiens (human) | ANGPTL5 | NP_835228.2 |
Xenopus tropicalis (tropical clawed frog) | angptl5 | XP_002935615.1 |
ANGPTL5 | XP_001095748.1 | |
Pan troglodytes (chimpanzee) | ANGPTL5 | XP_522161.2 |
Bos taurus (cattle) | ANGPTL5 | NP_001121541.1 |
Gallus gallus (chicken) | ANGPTL5 | NP_001184165.1 |
Canis lupus familiaris (dog) | ANGPTL5 | XP_005619916.1 |
Danio rerio (zebrafish) | angptl5 | XP_002666042.3 |
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Cobb J, Cule E, Moncrieffe H, Hinks A, Ursu S, Patrick F, Kassoumeri L, Flynn E, Bulatovi? M, Wulffraat N, van Zelst B, de Jonge R, Bohm M, Dolezalova P, Hirani S, Newman S, Whitworth P, Southwood TR, De Iorio M, , , , Wedderburn LR, Thomson W
The pharmacogenomics journal14(4)356-64(2014 Aug)
A motif in LILRB2 critical for Angptl2 binding and activation.
Deng M, Lu Z, Zheng J, Wan X, Chen X, Hirayasu K, Sun H, Lam Y, Chen L, Wang Q, Song C, Huang N, Gao GF, Jiang Y, Arase H, Zhang CC
Blood124(6)924-35(2014 Aug)
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development.
Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Huynh H, Hyunh H, Kang X, Silvany R, Wan X, Ye J, Cant? AP, Chen SH, Wang HY, Ward ES, Zhang CC
Nature485(7400)656-60(2012 May)
Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2r?-/- (NSG) mice.
Drake AC, Khoury M, Leskov I, Iliopoulou BP, Fragoso M, Lodish H, Chen J
PloS one6(4)e18382(2011 Apr)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rgamma-/- (NSG) mice
Title: Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2r?-/- (NSG) mice.
Maps to 11q22, mainly expressed in adult human heart.
Title: Identification of a novel human angiopoietin-like gene expressed mainly in heart.
The following ANGPTL5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ANGPTL5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu45723 | |
Clone ID Related Accession (Same CDS sequence) | XM_011542735.1 , XM_011542735.3 , XM_011542735.2 | |
Accession Version | XM_011542735.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-11 | |
Organism | Homo sapiens(Human) | |
Product | angiopoietin-related protein 5 isoform X1 | |
Comment |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011541037.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011542735.1 |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu45723 | |
Clone ID Related Accession (Same CDS sequence) | XM_011542735.1 , XM_011542735.3 , XM_011542735.2 | |
Accession Version | XM_011542735.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | angiopoietin-related protein 5 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011542735.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011541037.1 |
CDS | 1125..2096 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011542735.3 |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu45723 | |
Clone ID Related Accession (Same CDS sequence) | XM_011542735.1 , XM_011542735.3 , XM_011542735.2 | |
Accession Version | XM_011542735.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | angiopoietin-related protein 5 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011542735.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011541037.1 |
CDS | 591..1562 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011542735.2 |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu32080 | |
Clone ID Related Accession (Same CDS sequence) | NM_178127.5 , NM_178127.4 | |
Accession Version | NM_178127.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-29 | |
Organism | Homo sapiens(human) | |
Product | angiopoietin-related protein 5 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC049170.1, AP003383.2 and AK291523.1. On May 17, 2019 this sequence version replaced NM_178127.4. ##Evidence-Data-START## Transcript exon combination :: BC053957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149178, SAMEA2153980 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000334289.7/ ENSP00000335255.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_835228.2 |
CDS | 597..1763 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178127.5 |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu32080 | |
Clone ID Related Accession (Same CDS sequence) | NM_178127.5 , NM_178127.4 | |
Accession Version | NM_178127.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-17 | |
Organism | Homo sapiens(human) | |
Product | angiopoietin-related protein 5 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC049170.1, AP003383.2 and AK291523.1. On or before Aug 31, 2013 this sequence version replaced XM_005271496.1, NM_178127.3. ##Evidence-Data-START## Transcript exon combination :: BC049170.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149178, SAMEA2153980 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_835228.2 |
CDS | 597..1763 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178127.4 |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu92090 | |
Clone ID Related Accession (Same CDS sequence) | XM_017017466.1 , XM_017017466.2 | |
Accession Version | XM_017017466.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | angiopoietin-related protein 5 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016872955.1 |
CDS | 591..1337 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017017466.1 |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu92090 | |
Clone ID Related Accession (Same CDS sequence) | XM_017017466.1 , XM_017017466.2 | |
Accession Version | XM_017017466.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | angiopoietin-related protein 5 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017017466.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016872955.1 |
CDS | 1125..1871 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017017466.2 |
1 | ATGATGTCTC CATCCCAAGC CTCACTCTTA TTCTTAAATG TATGTATTTT TATTTGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. |
A motif in LILRB2 critical for Angptl2 binding and activation. |
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development. |
Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2r?-/- (NSG) mice. |
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |