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GABRB1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol GABRB1
Entrez Gene ID 2560
Full Name gamma-aminobutyric acid type A receptor beta1 subunit
Synonyms EIEE45
General protein information
Preferred Names

gamma-aminobutyric acid type A receptor beta1 subunit

Names

gamma-aminobutyric acid receptor subunit beta-1
gamma-aminobutyric acid (GABA) A receptor, beta 1

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

4

4p12

Summary The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008].
Disorder MIM:

137190


mRNA and Protein(s)

mRNA Protein Name
XM_017007985.1 XP_016863474.1 gamma-aminobutyric acid receptor subunit beta-1 isoform X1
NM_000812.3 NP_000803.2 gamma-aminobutyric acid receptor subunit beta-1 precursor
XM_017007986.1 XP_016863475.1 gamma-aminobutyric acid receptor subunit beta-1 isoform X2



Canis lupus familiaris (dog) GABRB1 XP_005628215.1
Bos taurus (cattle) GABRB1 NP_776969.1
Mus musculus (house mouse) Gabrb1 NP_032095.1
Macaca mulatta (rhesus monkey) GABRB1 XP_002804095.1
Rattus norvegicus (Norway rat) Gabrb1 NP_037088.1
Xenopus tropicalis (tropical clawed frog) gabrb1 XP_004911268.1
Homo sapiens (human) GABRB1 NP_000803.2
Gallus gallus (chicken) GABRQ NP_001161175.1
Pan troglodytes (chimpanzee) GABRB1 XP_001154620.1
Danio rerio (zebrafish) gabrb1 XP_002664179.2


Related articles in PubMed

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD.
Sundar IK, Yin Q, Baier BS, Yan L, Mazur W, Li D, Susiarjo M, Rahman I
Clinical epigenetics938(2017)

Epileptic encephalopathy de novo GABRB mutations impair GABA
Janve VS, Hernandez CC, Verdier KM, Hu N, Macdonald RL
Annals of neurology(2016 Mar)

PCDHB14- and GABRB1-like nervous system developmental genes are altered during early neuronal differentiation of NCCIT cells treated with ethanol.
Halder D, Mandal C, Lee BH, Lee JS, Choi MR, Chai JC, Lee YS, Jung KH, Chai YG
Human & experimental toxicology34(10)1017-27(2015 Oct)

Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia.
Bristow GC, Bostrom JA, Haroutunian V, Sodhi MS
Schizophrenia research167(1-3)57-63(2015 Sep)

GABAB1 and GABAB2 receptor subunits co-expressed in cultured human RPE cells regulate intracellular Ca2+ via Gi/o-protein and phospholipase C pathways.
Cheng ZY, Wang XP, Schmid KL, Han XG
Neuroscience280254-61(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results from genome-wide DNA methylation, functional network analysis and pyrosequencing, show selective CpG sites (NOS1AP, BID, and GABRB1) differentially methylated in smokers and chronic obstructive pulmonary disease patients compared to nonsmokers.
Title: DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD.

PCDHB14- and GABRB1-like nervous system developmental genes are altered during early neuronal differentiation of NCCIT cells treated with ethanol
Title: PCDHB14- and GABRB1-like nervous system developmental genes are altered during early neuronal differentiation of NCCIT cells treated with ethanol.

This study showed that in male group the expression of GABRB1 was generally lower in schizophrenia cases compared to the control, but was higher in female group.
Title: Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia.

Both mRNA and protein of GABAB receptor subunits, GABAB1 and GABAB2, were co-expressed in cultured human RPE cells; GABAB receptors regulate the [Ca2+]i via a pertussis toxin-sensitive Gi/o-protein pathway and a phospholipase C pathway
Title: GABAB1 and GABAB2 receptor subunits co-expressed in cultured human RPE cells regulate intracellular Ca2+ via Gi/o-protein and phospholipase C pathways.

study provides the first evidence for the involvement of the GABRB1 gene in the thalamus structure and their interactive effects on intelligence
Title: The GABRB1 gene is associated with thalamus volume and modulates the association between thalamus volume and intelligence.

The following GABRB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GABRB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu17601 NM_000812.3
Latest version!
Homo sapiens gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $265.30
$379.00
OHu95036 XM_017007985.1
Latest version!
Homo sapiens gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
OHu95037 XM_017007986.1
Latest version!
Homo sapiens gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu17601
Clone ID Related Accession (Same CDS sequence) NM_000812.3
Accession Version NM_000812.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1425bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-04
Organism Homo sapiens(Human)
Product gamma-aminobutyric acid receptor subunit beta-1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352362.1, AK225167.1, X14767.1 and AK225686.1. This sequence is a reference standard in the RefSeqGene project. On Jul 11, 2008 this sequence version replaced NM_000812.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.176131.1, SRR1803611.269538.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2151741 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTCTG GGGCTTCTCT CTTTCCCTGT GATGATTACC 
ATGGTCTGTT GTGCACACAG CACCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA
GTGGACAGAT TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTCGG AGGGCCCCCC
GTCGACGTTG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCCGA AGTGAATATG
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAAG ACAAAAGGCT TTCTTATTCT
GGAATCCCAC TGAACCTCAC CCTAGACAAT AGGGTAGCTG ACCAACTCTG GGTACCAGAC
ACCTACTTTC TGAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAATCGAATG
ATTCGACTGC ATCCTGATGG AACAGTTCTC TATGGACTCC GAATCACAAC CACAGCTGCA
TGTATGATGG ATCTTCGAAG ATATCCACTG GATGAGCAGA ACTGCACCCT GGAGATCGAA
AGTTATGGCT ATACCACTGA TGACATTGAA TTTTACTGGA ATGGAGGAGA AGGGGCAGTC
ACTGGTGTTA ATAAAATCGA ACTTCCTCAA TTTTCAATTG TTGACTACAA GATGGTGTCT
AAGAAGGTGG AGTTCACAAC AGGAGCGTAT CCACGACTGT CACTAAGTTT TCGTCTAAAG
AGAAACATTG GTTACTTCAT TTTGCAAACC TACATGCCTT CTACACTGAT TACAATTCTG
TCCTGGGTGT CTTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC
ACGACAGTGC TTACAATGAC AACCATCAGC ACCCACCTCA GGGAGACCCT GCCAAAGATC
CCTTATGTCA AAGCGATTGA TATTTATCTG ATGGGTTGCT TTGTGTTTGT GTTCCTGGCT
CTGCTGGAGT ATGCCTTTGT AAATTACATC TTCTTTGGGA AAGGCCCTCA GAAAAAGGGA
GCTAGCAAAC AAGACCAGAG TGCCAATGAG AAGAATAAAC TGGAGATGAA TAAAGTCCAG
GTCGACGCCC ACGGTAACAT TCTCCTCAGC ACCCTGGAAA TCCGGAATGA GACGAGTGGC
TCGGAAGTGC TCACGAGCGT GAGCGACCCC AAGGCCACCA TGTACTCCTA TGACAGCGCC
AGCATCCAGT ACCGCAAGCC CCTGAGCAGC CGCGAGGCCT ACGGGCGCGC CCTGGACCGG
CACGGGGTAC CCAGCAAGGG GCGCATCCGC AGGCGTGCCT CCCAGCTCAA AGTCAAGATC
CCCGACTTGA CTGATGTGAA TTCCATAGAC AAGTGGTCCC GAATGTTTTT CCCCATCACC
TTTTCTCTTT TTAATGTCGT CTATTGGCTT TACTATGTAC ACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000803.2
CDS375..1799
Misc Feature(1)360..362
Misc Feature(2)399..1790
Misc Feature(3)495..1103
Misc Feature(4)732..740
Misc Feature(5)912..920
Misc Feature(6)1110..1175
Misc Feature(7)1122..1781
Misc Feature(8)1185..1253
Misc Feature(9)1242..1307
Misc Feature(10)1287..1355
Misc Feature(11)1728..1793
Exon (1)1..454
Exon (2)455..546
Exon (3)547..614
Exon (4)615..835
Exon (5)836..918
Exon (6)919..1056
Exon (7)1057..1209
Exon (8)1210..1454
Exon (9)1455..2226
Translation

Target ORF information:

RefSeq Version NM_000812.3
Organism Homo sapiens(Human)
Definition Homo sapiens gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000812.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTCTG GGGCTTCTCT CTTTCCCTGT GATGATTACC 
ATGGTCTGTT GTGCACACAG CACCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA
GTGGACAGAT TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTCGG AGGGCCCCCC
GTCGACGTTG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCCGA AGTGAATATG
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAAG ACAAAAGGCT TTCTTATTCT
GGAATCCCAC TGAACCTCAC CCTAGACAAT AGGGTAGCTG ACCAACTCTG GGTACCAGAC
ACCTACTTTC TGAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAATCGAATG
ATTCGACTGC ATCCTGATGG AACAGTTCTC TATGGACTCC GAATCACAAC CACAGCTGCA
TGTATGATGG ATCTTCGAAG ATATCCACTG GATGAGCAGA ACTGCACCCT GGAGATCGAA
AGTTATGGCT ATACCACTGA TGACATTGAA TTTTACTGGA ATGGAGGAGA AGGGGCAGTC
ACTGGTGTTA ATAAAATCGA ACTTCCTCAA TTTTCAATTG TTGACTACAA GATGGTGTCT
AAGAAGGTGG AGTTCACAAC AGGAGCGTAT CCACGACTGT CACTAAGTTT TCGTCTAAAG
AGAAACATTG GTTACTTCAT TTTGCAAACC TACATGCCTT CTACACTGAT TACAATTCTG
TCCTGGGTGT CTTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC
ACGACAGTGC TTACAATGAC AACCATCAGC ACCCACCTCA GGGAGACCCT GCCAAAGATC
CCTTATGTCA AAGCGATTGA TATTTATCTG ATGGGTTGCT TTGTGTTTGT GTTCCTGGCT
CTGCTGGAGT ATGCCTTTGT AAATTACATC TTCTTTGGGA AAGGCCCTCA GAAAAAGGGA
GCTAGCAAAC AAGACCAGAG TGCCAATGAG AAGAATAAAC TGGAGATGAA TAAAGTCCAG
GTCGACGCCC ACGGTAACAT TCTCCTCAGC ACCCTGGAAA TCCGGAATGA GACGAGTGGC
TCGGAAGTGC TCACGAGCGT GAGCGACCCC AAGGCCACCA TGTACTCCTA TGACAGCGCC
AGCATCCAGT ACCGCAAGCC CCTGAGCAGC CGCGAGGCCT ACGGGCGCGC CCTGGACCGG
CACGGGGTAC CCAGCAAGGG GCGCATCCGC AGGCGTGCCT CCCAGCTCAA AGTCAAGATC
CCCGACTTGA CTGATGTGAA TTCCATAGAC AAGTGGTCCC GAATGTTTTT CCCCATCACC
TTTTCTCTTT TTAATGTCGT CTATTGGCTT TACTATGTAC ACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu95036
Clone ID Related Accession (Same CDS sequence) XM_017007985.1
Accession Version XM_017007985.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 774bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product gamma-aminobutyric acid receptor subunit beta-1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTGTCTA AGAAGGTGGA GTTCACAACA GGAGCGTATC CACGACTGTC ACTAAGTTTT 
CGTCTAAAGA GAAACATTGG TTACTTCATT TTGCAAACCT ACATGCCTTC TACACTGATT
ACAATTCTGT CCTGGGTGTC TTTTTGGATC AACTATGATG CATCTGCAGC CAGAGTCGCA
CTAGGAATCA CGACAGTGCT TACAATGACA ACCATCAGCA CCCACCTCAG GGAGACCCTG
CCAAAGATCC CTTATGTCAA AGCGATTGAT ATTTATCTGA TGGGTTGCTT TGTGTTTGTG
TTCCTGGCTC TGCTGGAGTA TGCCTTTGTA AATTACATCT TCTTTGGGAA AGGCCCTCAG
AAAAAGGGAG CTAGCAAACA AGACCAGAGT GCCAATGAGA AGAATAAACT GGAGATGAAT
AAAGTCCAGG TCGACGCCCA CGGTAACATT CTCCTCAGCA CCCTGGAAAT CCGGAATGAG
ACGAGTGGCT CGGAAGTGCT CACGAGCGTG AGCGACCCCA AGGCCACCAT GTACTCCTAT
GACAGCGCCA GCATCCAGTA CCGCAAGCCC CTGAGCAGCC GCGAGGCCTA CGGGCGCGCC
CTGGACCGGC ACGGGGTACC CAGCAAGGGG CGCATCCGCA GGCGTGCCTC CCAGCTCAAA
GTCAAGATCC CCGACTTGAC TGATGTGAAT TCCATAGACA AGTGGTCCCG AATGTTTTTC
CCCATCACCT TTTCTCTTTT TAATGTCGTC TATTGGCTTT ACTATGTACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016863474.1
CDS164..937
Translation

Target ORF information:

RefSeq Version XM_017007985.1
Organism Homo sapiens(Human)
Definition Homo sapiens gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017007985.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTGTCTA AGAAGGTGGA GTTCACAACA GGAGCGTATC CACGACTGTC ACTAAGTTTT 
CGTCTAAAGA GAAACATTGG TTACTTCATT TTGCAAACCT ACATGCCTTC TACACTGATT
ACAATTCTGT CCTGGGTGTC TTTTTGGATC AACTATGATG CATCTGCAGC CAGAGTCGCA
CTAGGAATCA CGACAGTGCT TACAATGACA ACCATCAGCA CCCACCTCAG GGAGACCCTG
CCAAAGATCC CTTATGTCAA AGCGATTGAT ATTTATCTGA TGGGTTGCTT TGTGTTTGTG
TTCCTGGCTC TGCTGGAGTA TGCCTTTGTA AATTACATCT TCTTTGGGAA AGGCCCTCAG
AAAAAGGGAG CTAGCAAACA AGACCAGAGT GCCAATGAGA AGAATAAACT GGAGATGAAT
AAAGTCCAGG TCGACGCCCA CGGTAACATT CTCCTCAGCA CCCTGGAAAT CCGGAATGAG
ACGAGTGGCT CGGAAGTGCT CACGAGCGTG AGCGACCCCA AGGCCACCAT GTACTCCTAT
GACAGCGCCA GCATCCAGTA CCGCAAGCCC CTGAGCAGCC GCGAGGCCTA CGGGCGCGCC
CTGGACCGGC ACGGGGTACC CAGCAAGGGG CGCATCCGCA GGCGTGCCTC CCAGCTCAAA
GTCAAGATCC CCGACTTGAC TGATGTGAAT TCCATAGACA AGTGGTCCCG AATGTTTTTC
CCCATCACCT TTTCTCTTTT TAATGTCGTC TATTGGCTTT ACTATGTACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu95037
Clone ID Related Accession (Same CDS sequence) XM_017007986.1
Accession Version XM_017007986.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product gamma-aminobutyric acid receptor subunit beta-1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTGGACAG TACAAAATCG AGAGAGTCTG GGGCTTCTCT CTTTCCCTGT GATGATTACC 
ATGGTCTGTT GTGCACACAG CACCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA
GTGGACAGAT TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTCGG AGGGCCCCCC
GTCGACGTTG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCCGA AGTGAATATG
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAAG ACAAAAGGCT TTCTTATTCT
GGAATCCCAC TGAACCTCAC CCTAGACAAT AGGGTAGCTG ACCAACTCTG GGTACCAGAC
ACCTACTTTC TGAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAATCGAATG
ATTCGACTGC ATCCTGATGG AACAGTTCTC TATGGACTCC GATGGAGTCT TCCTATGTCG
CCCAGGCTGA AGTGCAGTGG CACGGTCTCA ACTCGAAGCA ACCTCCACCT CCCAGGTTCA
AACGAGTATC CTACCTCAGC CTCCCATGTA GCTGGGATTA CAGGCATGCG CCACCATGCT
CAGCTAATTT TTGTGTTTTT AGTAGAGACG GAGTTTCACC ATGTTGGCCA GGCTGGCCTT
GAGCTCCTGA CCTCAGATGA TCCACCTGCC TCGGCCACCC AAAGTGCAGG TTTATCTTTT
CTAAATCTTT TTTCTTCTTT TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016863475.1
CDS100..843
Translation

Target ORF information:

RefSeq Version XM_017007986.1
Organism Homo sapiens(Human)
Definition Homo sapiens gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017007986.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTGGACAG TACAAAATCG AGAGAGTCTG GGGCTTCTCT CTTTCCCTGT GATGATTACC 
ATGGTCTGTT GTGCACACAG CACCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA
GTGGACAGAT TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTCGG AGGGCCCCCC
GTCGACGTTG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCCGA AGTGAATATG
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAAG ACAAAAGGCT TTCTTATTCT
GGAATCCCAC TGAACCTCAC CCTAGACAAT AGGGTAGCTG ACCAACTCTG GGTACCAGAC
ACCTACTTTC TGAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAATCGAATG
ATTCGACTGC ATCCTGATGG AACAGTTCTC TATGGACTCC GATGGAGTCT TCCTATGTCG
CCCAGGCTGA AGTGCAGTGG CACGGTCTCA ACTCGAAGCA ACCTCCACCT CCCAGGTTCA
AACGAGTATC CTACCTCAGC CTCCCATGTA GCTGGGATTA CAGGCATGCG CCACCATGCT
CAGCTAATTT TTGTGTTTTT AGTAGAGACG GAGTTTCACC ATGTTGGCCA GGCTGGCCTT
GAGCTCCTGA CCTCAGATGA TCCACCTGCC TCGGCCACCC AAAGTGCAGG TTTATCTTTT
CTAAATCTTT TTTCTTCTTT TTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD.
Clinical epigenetics938(2017)
Sundar IK,Yin Q,Baier BS,Yan L,Mazur W,Li D,Susiarjo M,Rahman I


book

Epileptic encephalopathy de novo GABRB mutations impair GABA
Annals of neurology(2016 Mar)
Janve VS,Hernandez CC,Verdier KM,Hu N,Macdonald RL


book

PCDHB14- and GABRB1-like nervous system developmental genes are altered during early neuronal differentiation of NCCIT cells treated with ethanol.
Human & experimental toxicology34(10)1017-27(2015 Oct)
Halder D,Mandal C,Lee BH,Lee JS,Choi MR,Chai JC,Lee YS,Jung KH,Chai YG


book

Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia.
Schizophrenia research167(1-3)57-63(2015 Sep)
Bristow GC,Bostrom JA,Haroutunian V,Sodhi MS


book

GABAB1 and GABAB2 receptor subunits co-expressed in cultured human RPE cells regulate intracellular Ca2+ via Gi/o-protein and phospholipase C pathways.
Neuroscience280254-61(2014 Nov)
Cheng ZY,Wang XP,Schmid KL,Han XG


 
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