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BRI3 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol BRI3
Entrez Gene ID 25798
Full Name brain protein I3
Synonyms I3
General protein information
Preferred Names

brain protein I3

Names

brain protein I3
pRGR2
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

7

7q21.3
Disorder MIM:

615628


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_017011933.1 XP_016867422.1 brain protein I3 isoform X2
NM_015379.5 NP_056194.1 brain protein I3 isoform a
XM_017011935.2 XP_016867424.1 brain protein I3 isoform X3
NM_015379.4 NP_056194.1 brain protein I3 isoform a
XM_017011934.2 XP_016867423.1 brain protein I3 isoform X2
NM_001159491.1 NP_001152963.1 brain protein I3 isoform b
XM_017011931.1 XP_016867420.1 brain protein I3 isoform X1
XM_017011931.2 XP_016867420.1 brain protein I3 isoform X1
XM_017011933.2 XP_016867422.1 brain protein I3 isoform X2
XM_017011936.1 XP_016867425.1 brain protein I3 isoform X4
XM_017011934.1 XP_016867423.1 brain protein I3 isoform X2
XM_017011932.1 XP_016867421.1 brain protein I3 isoform X2
XM_017011935.1 XP_016867424.1 brain protein I3 isoform X3
NM_001159491.2 NP_001152963.1 brain protein I3 isoform b
XM_017011932.2 XP_016867421.1 brain protein I3 isoform X2

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) BRI3 NP_001239480.1
BRI3 XP_001093359.1
Bos taurus (cattle) BRI3 NP_001035673.1
Xenopus tropicalis (tropical clawed frog) bri3 NP_001116284.1
Homo sapiens (human) BRI3 NP_056194.1
Canis lupus familiaris (dog) BRI3 XP_005621165.1
Mus musculus (house mouse) Bri3 NP_061242.3
Danio rerio (zebrafish) bri3 NP_001186968.1
Rattus norvegicus (Norway rat) Bri3 NP_001009604.1

Gene Ontology


Bibliography

Related articles in PubMed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets.
Kavak E, Najafov A, Ozturk N, Seker T, Cavusoglu K, Aslan T, Duru AD, Saygili T, Hoxhaj G, Hiz MC, Unal DO, Birg?l-Iyison N, Ozturk M, Koman A
Cellular signalling22(10)1523-35(2010 Oct)

BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.
Matsuda S, Matsuda Y, D'Adamio L
The Journal of biological chemistry284(23)15815-25(2009 Jun)

BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.
Gong Y, Wu J, Qiang H, Liu B, Chi Z, Chen T, Yin B, Peng X, Yuan J
BMB reports41(4)287-93(2008 Apr)

A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients.
Bandr?s E, Malumbres R, Cubedo E, Honorato B, Zarate R, Labarga A, Gabisu U, Sola JJ, Garc?a-Foncillas J
Oncology reports17(5)1089-94(2007 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In the context of hepatocellular carcinoma cells, BRI3 is a target of WNT signaling.
Title: Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets.

BRI3 inhibits the various processing of amyloid protein precursor by blocking the access of alpha- and beta-secretases.
Title: BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.

Possible roles of BRI3 in the process of neuronal differentiation.
Title: BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.

BRI3 RNA is expressed less in stage 3 colon cancer in comparison to stage 2 colon cancer, and it is among 8 genes which can be used as a gene signature to differentiate colon cancer stages.
Title: A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients.

An X-ray data set was collected to 1.6 A resolution using synchrotron radiation, of a ligandin recombinant fusion protein.
Title: Crystallization and preliminary X-ray analysis of the GST-fused human Bri3 N-terminal domain.

The following BRI3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BRI3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu26405 NM_015379.5
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu26224 NM_001159491.2
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu41467 XM_017011936.1
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97138 XM_017011931.2
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97139 XM_017011932.2
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97139 XM_017011933.2
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97139 XM_017011934.2
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97140 XM_017011935.2
Latest version!		 Homo sapiens brain protein I3 (BRI3), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
View Old Accession Versions >>
OHu26405 NM_015379.4 Homo sapiens brain protein I3 (BRI3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu97138 XM_017011931.1 Homo sapiens brain protein I3 (BRI3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97139 XM_017011933.1 Homo sapiens brain protein I3 (BRI3), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97139 XM_017011934.1 Homo sapiens brain protein I3 (BRI3), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97140 XM_017011935.1 Homo sapiens brain protein I3 (BRI3), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu26224 NM_001159491.1 Homo sapiens brain protein I3 (BRI3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu97139 XM_017011932.1 Homo sapiens brain protein I3 (BRI3), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu26405
Clone ID Related Accession (Same CDS sequence) NM_015379.5 , NM_015379.4
Accession Version NM_015379.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 378bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-29
Organism Homo sapiens(human)
Product brain protein I3 isoform a
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ083249.1, BC062370.1, BQ018487.1 and AC093169.3. On May 17, 2019 this sequence version replaced NM_015379.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD101728.1, HY026844.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGGTTG GGGTGCTGGA GGACTGCTTC ACCTTCCTGG GCATCTTCCT GGCCATCATC 
CTCTTCCCCT TTGGGTTCAT TTGCTGTTTT GCCTTGAGGA AGCGACGATG CCCCAACTGT 
GGAGCCACCT TCGCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_056194.1
CDS111..488
Translation

Target ORF information:

RefSeq Version NM_015379.5
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_015379.5

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGGTTG GGGTGCTGGA GGACTGCTTC ACCTTCCTGG GCATCTTCCT GGCCATCATC 
CTCTTCCCCT TTGGGTTCAT TTGCTGTTTT GCCTTGAGGA AGCGACGATG CCCCAACTGT 
GGAGCCACCT TCGCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26405
Clone ID Related Accession (Same CDS sequence) NM_015379.5 , NM_015379.4
Accession Version NM_015379.4 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 378bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-06-23
Organism Homo sapiens(human)
Product brain protein I3 isoform a
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ083249.1, BC062370.1 and BQ018487.1. On Apr 24, 2009 this sequence version replaced NM_015379.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279842.9919.1, ERR279843.3492.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGGTTG GGGTGCTGGA GGACTGCTTC ACCTTCCTGG GCATCTTCCT GGCCATCATC 
CTCTTCCCCT TTGGGTTCAT TTGCTGTTTT GCCTTGAGGA AGCGACGATG CCCCAACTGT 
GGAGCCACCT TCGCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_056194.1
CDS130..507
Translation

Target ORF information:

RefSeq Version NM_015379.4
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_015379.4

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGGTTG GGGTGCTGGA GGACTGCTTC ACCTTCCTGG GCATCTTCCT GGCCATCATC 
CTCTTCCCCT TTGGGTTCAT TTGCTGTTTT GCCTTGAGGA AGCGACGATG CCCCAACTGT 
GGAGCCACCT TCGCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26224
Clone ID Related Accession (Same CDS sequence) NM_001159491.1 , NM_001159491.2
Accession Version NM_001159491.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 297bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-06-23
Organism Homo sapiens(human)
Product brain protein I3 isoform b
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ083249.1, BF108440.1 and BF432881.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform b which has a shorter and distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF432881.1, BF111065.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820699 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGCACC AGAGGTCATC CTGGCTTTAC ACGTATCCTT TGAGAGTCTG TACCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001152963.1
CDS130..426
Translation

Target ORF information:

RefSeq Version NM_001159491.1
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001159491.1

ORF Insert Sequence:

1
61
121
181
241
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGCACC AGAGGTCATC CTGGCTTTAC ACGTATCCTT TGAGAGTCTG TACCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26224
Clone ID Related Accession (Same CDS sequence) NM_001159491.1 , NM_001159491.2
Accession Version NM_001159491.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 297bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-05-31
Organism Homo sapiens(human)
Product brain protein I3 isoform b
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ083249.1, BF108440.1 and BF432881.1. On Jun 1, 2019 this sequence version replaced NM_001159491.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform b which has a shorter and distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF432881.1, BF111065.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820699 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGCACC AGAGGTCATC CTGGCTTTAC ACGTATCCTT TGAGAGTCTG TACCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001152963.1
CDS111..407
Translation

Target ORF information:

RefSeq Version NM_001159491.2
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001159491.2

ORF Insert Sequence:

1
61
121
181
241
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGGCACC AGAGGTCATC CTGGCTTTAC ACGTATCCTT TGAGAGTCTG TACCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu41467
Clone ID Related Accession (Same CDS sequence) XM_017011936.1
Accession Version XM_017011936.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 318bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product brain protein I3 isoform X4
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGCAACT TCGTGTACGA CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA 
AGACCCTATC AGCAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867425.1
CDS124..441
Translation

Target ORF information:

RefSeq Version XM_017011936.1
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011936.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC 
AGCCGGACCG TCACCCGCTA TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC 
TGCAGCAACT TCGTGTACGA CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA 
AGACCCTATC AGCAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97138
Clone ID Related Accession (Same CDS sequence) XM_017011931.1 , XM_017011931.2
Accession Version XM_017011931.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 468bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product brain protein I3 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTACATCTGA AGACATCTGA GTCTGACACT 
GGCCACCCAG GCTTCCCTTG TCCCAGCTCA GGATTCAACC CTTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867420.1
CDS73..540
Translation

Target ORF information:

RefSeq Version XM_017011931.1
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011931.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTACATCTGA AGACATCTGA GTCTGACACT 
GGCCACCCAG GCTTCCCTTG TCCCAGCTCA GGATTCAACC CTTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97138
Clone ID Related Accession (Same CDS sequence) XM_017011931.1 , XM_017011931.2
Accession Version XM_017011931.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 468bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product brain protein I3 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017011931.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTACATCTGA AGACATCTGA GTCTGACACT 
GGCCACCCAG GCTTCCCTTG TCCCAGCTCA GGATTCAACC CTTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867420.1
CDS105..572
Translation

Target ORF information:

RefSeq Version XM_017011931.2
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011931.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTACATCTGA AGACATCTGA GTCTGACACT 
GGCCACCCAG GCTTCCCTTG TCCCAGCTCA GGATTCAACC CTTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97139
Clone ID Related Accession (Same CDS sequence) XM_017011933.1 , XM_017011934.2 , XM_017011933.2 , XM_017011934.1 , XM_017011932.1 , XM_017011932.2
Accession Version XM_017011933.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 450bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product brain protein I3 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867422.1
CDS73..522
Translation

Target ORF information:

RefSeq Version XM_017011933.1
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011933.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97139
Clone ID Related Accession (Same CDS sequence) XM_017011933.1 , XM_017011934.2 , XM_017011933.2 , XM_017011934.1 , XM_017011932.1 , XM_017011932.2
Accession Version XM_017011934.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 450bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product brain protein I3 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017011934.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867423.1
CDS105..554
Translation

Target ORF information:

RefSeq Version XM_017011934.2
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011934.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97139
Clone ID Related Accession (Same CDS sequence) XM_017011933.1 , XM_017011934.2 , XM_017011933.2 , XM_017011934.1 , XM_017011932.1 , XM_017011932.2
Accession Version XM_017011933.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 450bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product brain protein I3 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017011933.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867422.1
CDS105..554
Translation

Target ORF information:

RefSeq Version XM_017011933.2
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011933.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97139
Clone ID Related Accession (Same CDS sequence) XM_017011933.1 , XM_017011934.2 , XM_017011933.2 , XM_017011934.1 , XM_017011932.1 , XM_017011932.2
Accession Version XM_017011934.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 450bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product brain protein I3 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867423.1
CDS73..522
Translation

Target ORF information:

RefSeq Version XM_017011934.1
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011934.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97139
Clone ID Related Accession (Same CDS sequence) XM_017011933.1 , XM_017011934.2 , XM_017011933.2 , XM_017011934.1 , XM_017011932.1 , XM_017011932.2
Accession Version XM_017011932.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 450bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product brain protein I3 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867421.1
CDS73..522
Translation

Target ORF information:

RefSeq Version XM_017011932.1
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011932.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97139
Clone ID Related Accession (Same CDS sequence) XM_017011933.1 , XM_017011934.2 , XM_017011933.2 , XM_017011934.1 , XM_017011932.1 , XM_017011932.2
Accession Version XM_017011932.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 450bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product brain protein I3 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017011932.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867421.1
CDS105..554
Translation

Target ORF information:

RefSeq Version XM_017011932.2
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011932.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG GTGAGAGCTC AGGGCAGACA GGTCCACTGC 
TCCAGAAACG CCCATGTGTG GAGGAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97140
Clone ID Related Accession (Same CDS sequence) XM_017011935.2 , XM_017011935.1
Accession Version XM_017011935.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 405bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product brain protein I3 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017011935.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG ACATACAGAA AATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867424.1
CDS105..509
Translation

Target ORF information:

RefSeq Version XM_017011935.2
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011935.2

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG ACATACAGAA AATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu97140
Clone ID Related Accession (Same CDS sequence) XM_017011935.2 , XM_017011935.1
Accession Version XM_017011935.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 405bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product brain protein I3 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG ACATACAGAA AATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016867424.1
CDS73..477
Translation

Target ORF information:

RefSeq Version XM_017011935.1
Organism Homo sapiens(human)
Definition Homo sapiens brain protein I3 (BRI3), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017011935.1

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGACCACA AGCCGCTGCT GCAGGAGCGG CCGCCCGCCT ACAACCTGGA GGCCGGCCAG 
GGCGACTACG CGTGCGGCCC GCACGGCTAC GGCGCCATCC CCGCCGCGCC CCCGCCGCCG 
CCCTACCCCT ACCTCGTCAC AGGTGGGCCC GTAACCAACT TTCCCCGCCG GCGGCTTCCG 
AGGGATACCC ACCCACCATC CCAGGGTCTA CAACATCCAC AGCCGGACCG TCACCCGCTA 
TCCTGCCAAC TCTATCGTGG TCGTAGGAGG CTGTCCTGTC TGCAGCAACT TCGTGTACGA 
CGACGGGAAC CAACCCCTCC TACCGGCAAA GAGGGAGAAA AGACCCTATC AGCAGTAGAC 
ATGTGGACGG CAACCTCCCT GAACAACCTG ACATACAGAA AATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF


book

Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets.
Cellular signalling22(10)1523-35(2010 Oct)
Kavak E,Najafov A,Ozturk N,Seker T,Cavusoglu K,Aslan T,Duru AD,Saygili T,Hoxhaj G,Hiz MC,Unal DO,Birg?l-Iyison N,Ozturk M,Koman A


book

BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.
The Journal of biological chemistry284(23)15815-25(2009 Jun)
Matsuda S,Matsuda Y,D'Adamio L


book

BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.
BMB reports41(4)287-93(2008 Apr)
Gong Y,Wu J,Qiang H,Liu B,Chi Z,Chen T,Yin B,Peng X,Yuan J


book

A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients.
Oncology reports17(5)1089-94(2007 May)
Bandr?s E,Malumbres R,Cubedo E,Honorato B,Zarate R,Labarga A,Gabisu U,Sola JJ,Garc?a-Foncillas J