OSBPL3 cDNA ORF clone, Homo sapiens(human)
Gene Symbol | OSBPL3 |
Entrez Gene ID | 26031 |
Full Name | oxysterol binding protein like 3 |
Synonyms | ORP-3,ORP3,OSBP3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]. |
Disorder MIM: |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_015550.3 | NP_056365.1 | oxysterol-binding protein-related protein 3 isoform a |
XM_011515258.2 | XP_011513560.1 | oxysterol-binding protein-related protein 3 isoform X1 |
XM_006715681.3 | XP_006715744.1 | oxysterol-binding protein-related protein 3 isoform X2 |
XM_006715682.3 | XP_006715745.1 | oxysterol-binding protein-related protein 3 isoform X3 |
XM_017011948.1 | XP_016867437.1 | oxysterol-binding protein-related protein 3 isoform X4 |
XM_006715684.4 | XP_006715747.1 | oxysterol-binding protein-related protein 3 isoform X7 |
XM_011515258.1 | XP_011513560.1 | oxysterol-binding protein-related protein 3 isoform X1 |
NM_145320.2 | NP_663160.1 | oxysterol-binding protein-related protein 3 isoform b |
NM_145321.2 | NP_663161.1 | oxysterol-binding protein-related protein 3 isoform c |
XM_017011949.1 | XP_016867438.1 | oxysterol-binding protein-related protein 3 isoform X6 |
XM_005249698.2 | XP_005249755.1 | oxysterol-binding protein-related protein 3 isoform X1 |
XM_006715684.3 | XP_006715747.1 | oxysterol-binding protein-related protein 3 isoform X7 |
NM_145322.2 | NP_663162.1 | oxysterol-binding protein-related protein 3 isoform d |
XM_006715683.3 | XP_006715746.1 | oxysterol-binding protein-related protein 3 isoform X5 |
NM_015550.4 | NP_056365.1 | oxysterol-binding protein-related protein 3 isoform a |
XM_005249698.3 | XP_005249755.1 | oxysterol-binding protein-related protein 3 isoform X1 |
XM_011515259.2 | XP_011513561.1 | oxysterol-binding protein-related protein 3 isoform X4 |

Pan troglodytes (chimpanzee) | OSBPL3 | XP_001160331.2 |
Canis lupus familiaris (dog) | OSBPL3 | XP_863760.2 |
Danio rerio (zebrafish) | si:dkey-15j7.2 | XP_005158031.1 |
Bos taurus (cattle) | OSBPL3 | NP_001179830.2 |
Rattus norvegicus (Norway rat) | Osbpl3 | XP_006236577.1 |
Oryza sativa (rice) | Os03g0704700 | NP_001173604.1 |
Xenopus tropicalis (tropical clawed frog) | osbpl3 | NP_001243848.1 |
Homo sapiens (human) | OSBPL3 | NP_056365.1 |
Gallus gallus (chicken) | OSBPL3 | XP_004939413.1 |
Arabidopsis thaliana (thale cress) | ORP1B | NP_180660.1 |
OSBPL3 | XP_002803396.1 | |
Mus musculus (house mouse) | Osbpl3 | NP_082157.2 |

Related articles in PubMed
Oxysterol-binding protein ORP3 rescues the Amyotrophic Lateral Sclerosis-linked mutant VAPB phenotype.
Darbyson A, Ngsee JK
Experimental cell research341(1)18-31(2016 Feb)
OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity.
Weber-Boyvat M, Kentala H, Lilja J, Vihervaara T, Hanninen R, Zhou Y, Per?nen J, Nyman TA, Ivaska J, Olkkonen VM
Experimental cell research331(2)278-91(2015 Feb)
Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism.
Olkkonen VM, Li S
Progress in lipid research52(4)529-38(2013 Oct)
Oxysterol-binding proteins: functions in cell regulation beyond lipid metabolism.
Weber-Boyvat M, Zhong W, Yan D, Olkkonen VM
Biochemical pharmacology86(1)89-95(2013 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
It indicates that VAPB along with ORP3 plays a central role in maintenance of the intracellular PtdIns4P gradient.
Title: Oxysterol-binding protein ORP3 rescues the Amyotrophic Lateral Sclerosis-linked mutant VAPB phenotype.
phosphorylation of ORP3 controls its association with VAPA. Furthermore, ORP3-VAPA complexes stimulate R-Ras signaling.
Title: OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
The present findings demonstrate a new function of ORP3 as part of the machinery that controls the actin cytoskeleton, cell polarity and cell adhesion.
Title: The R-Ras interaction partner ORP3 regulates cell adhesion.
The intracellular targeting determinants of oxysterol binding protein (OSBP)-related protein 3 (ORP3) were studied using a series of truncated and point mutated constructs.
Title: Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants.
The following OSBPL3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OSBPL3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OHu12598![]() |
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Clone ID Related Accession (Same CDS sequence) | NM_015550.3 , XM_011515258.2 , XM_011515258.1 , XM_005249698.2 , NM_015550.4 , XM_005249698.3 | |
Accession Version | NM_015550.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2664bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-02 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform a | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR003143.1, AB014604.2, AC003093.1, AY008372.1 and AW241639.1. On Aug 24, 2013 this sequence version replaced NM_015550.2. Transcript Variant: This variant (1) encodes the longest isoform (a). Isoform a contains a pleckstrin homology domain and a sterol-binding domain. It is also known as isoform 1a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF392444.1, AY008372.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_056365.1 |
CDS | 477..3140 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12598![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_015550.3 , XM_011515258.2 , XM_011515258.1 , XM_005249698.2 , NM_015550.4 , XM_005249698.3 | |
Accession Version | NM_015550.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2664bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-26 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform a | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR003143.1, AB014604.2, AC003093.1 and AY008372.1. On Nov 23, 2018 this sequence version replaced NM_015550.3. Transcript Variant: This variant (1) encodes the longest isoform (a). Isoform a contains a pleckstrin homology domain and a sterol-binding domain. It is also known as isoform 1a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY008372.1, AF392444.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000313367.7/ ENSP00000315410.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_056365.1 |
CDS | 443..3106 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12598![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_015550.3 , XM_011515258.2 , XM_011515258.1 , XM_005249698.2 , NM_015550.4 , XM_005249698.3 | |
Accession Version | XM_011515258.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2664bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515258.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011513560.1 |
CDS | 274..2937 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12598![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_015550.3 , XM_011515258.2 , XM_011515258.1 , XM_005249698.2 , NM_015550.4 , XM_005249698.3 | |
Accession Version | XM_011515258.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2664bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-11 | |
Organism | Homo sapiens(Human) | |
Product | oxysterol-binding protein-related protein 3 isoform X1 | |
Comment |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011513560.1 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12598![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_015550.3 , XM_011515258.2 , XM_011515258.1 , XM_005249698.2 , NM_015550.4 , XM_005249698.3 | |
Accession Version | XM_005249698.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2664bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-11 | |
Organism | Homo sapiens(Human) | |
Product | oxysterol-binding protein-related protein 3 isoform X1 | |
Comment |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005249755.1 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12598![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_015550.3 , XM_011515258.2 , XM_011515258.1 , XM_005249698.2 , NM_015550.4 , XM_005249698.3 | |
Accession Version | XM_005249698.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2664bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249698.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005249755.1 |
CDS | 197..2860 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu41140 | |
Clone ID Related Accession (Same CDS sequence) | XM_006715684.4 , XM_006715684.3 | |
Accession Version | XM_006715684.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X7 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006715684.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCAGCGG AGAGAGAGAA ACTGAAGCAG CTGATGGAGC AGGATGCCTC CTCCTCCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006715747.1 |
CDS | 1508..3112 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGTCAGCGG AGAGAGAGAA ACTGAAGCAG CTGATGGAGC AGGATGCCTC CTCCTCCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu41140 | |
Clone ID Related Accession (Same CDS sequence) | XM_006715684.4 , XM_006715684.3 | |
Accession Version | XM_006715684.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X7 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006715684.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCAGCGG AGAGAGAGAA ACTGAAGCAG CTGATGGAGC AGGATGCCTC CTCCTCCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006715747.1 |
CDS | 1193..2797 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGTCAGCGG AGAGAGAGAA ACTGAAGCAG CTGATGGAGC AGGATGCCTC CTCCTCCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu66728 | |
Clone ID Related Accession (Same CDS sequence) | XM_017011948.1 , XM_011515259.2 | |
Accession Version | XM_017011948.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2532bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATTACA CCCAGGAGCC ACCAGTTCAG AAAGGATTTT TGCTGAAAAA GAGGAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016867437.1 |
CDS | 766..3297 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGAATTACA CCCAGGAGCC ACCAGTTCAG AAAGGATTTT TGCTGAAAAA GAGGAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu66728 | |
Clone ID Related Accession (Same CDS sequence) | XM_017011948.1 , XM_011515259.2 | |
Accession Version | XM_011515259.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2532bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515259.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATTACA CCCAGGAGCC ACCAGTTCAG AAAGGATTTT TGCTGAAAAA GAGGAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011513561.1 |
CDS | 903..3434 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGAATTACA CCCAGGAGCC ACCAGTTCAG AAAGGATTTT TGCTGAAAAA GAGGAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12556 | |
Clone ID Related Accession (Same CDS sequence) | XM_006715682.3 , NM_145321.2 | |
Accession Version | NM_145321.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2556bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-24 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform c | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF323727.1, AF491783.1, AB014604.2, AC003093.1, AY008372.1 and AW241639.1. On Aug 24, 2013 this sequence version replaced NM_145321.1. Transcript Variant: This variant (3) lacks an in-frame exon compared to variant 1, resulting in a shorter isoform (c) compared to isoform a. Isoform c contains a pleckstrin homology domain and a sterol-binding domain. It is also known as isoform 1c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF491783.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_663161.1 |
CDS | 150..2705 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12739 | |
Clone ID Related Accession (Same CDS sequence) | NM_145322.2 , XM_006715683.3 | |
Accession Version | NM_145322.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2463bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-24 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform d | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF323727.1, AF491784.1, AB014604.2, AC003093.1, AY008372.1 and AW241639.1. On Aug 24, 2013 this sequence version replaced NM_145322.1. Transcript Variant: This variant (4) lacks two in-frame exons compared to variant 1, resulting in a shorter isoform (d) compared to isoform a. Isoform d contains a pleckstrin homology domain and a sterol-binding domain. It is also known as isoform 1d. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.183719.1, AF491784.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_663162.1 |
CDS | 150..2612 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12915 | |
Clone ID Related Accession (Same CDS sequence) | XM_006715681.3 , NM_145320.2 | |
Accession Version | NM_145320.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2571bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-24 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform b | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF323727.1, AF491782.1, AB014604.2, AC003093.1, AY008372.1 and AW241639.1. On Aug 24, 2013 this sequence version replaced NM_145320.1. Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1, resulting in a shorter isoform (b) compared to isoform a. Isoform b contains a pleckstrin homology domain and a sterol-binding domain. It is also known as isoform 1b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF491782.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_663160.1 |
CDS | 150..2720 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12556 | |
Clone ID Related Accession (Same CDS sequence) | XM_006715682.3 , NM_145321.2 | |
Accession Version | XM_006715682.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2556bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006715682.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006715745.1 |
CDS | 483..3038 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12739 | |
Clone ID Related Accession (Same CDS sequence) | NM_145322.2 , XM_006715683.3 | |
Accession Version | XM_006715683.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2463bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006715683.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006715746.1 |
CDS | 483..2945 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12915 | |
Clone ID Related Accession (Same CDS sequence) | XM_006715681.3 , NM_145320.2 | |
Accession Version | XM_006715681.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2571bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006715681.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006715744.1 |
CDS | 464..3034 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGATGAGTG ATGAGAAGAA CCTTGGTGTG TCCCAAAAAT TGGTATCACC TTCAAGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu97146 | |
Clone ID Related Accession (Same CDS sequence) | XM_017011949.1 | |
Accession Version | XM_017011949.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2424bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | oxysterol-binding protein-related protein 3 isoform X6 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATTACA CCCAGGAGCC ACCAGTTCAG AAAGGATTTT TGCTGAAAAA GAGGAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016867438.1 |
CDS | 903..3326 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGAATTACA CCCAGGAGCC ACCAGTTCAG AAAGGATTTT TGCTGAAAAA GAGGAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity. |
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Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism. |
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Oxysterol-binding proteins: functions in cell regulation beyond lipid metabolism. |