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AMELX cDNA ORF clone, Homo sapiens (human)

Gene Symbol AMELX
Entrez Gene ID 265
Full Name amelogenin, X-linked
Synonyms AI1E, AIH1, ALGN, AMG, AMGL, AMGX
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp22.31-p22.1

Summary This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

300391

Disorder Html: Amelogenesis imperfecta, hypoplastic/hypomaturation type, 301200 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_011545489 XP_011543791 amelogenin, X isoform isoform X1
NM_001142 NP_001133 amelogenin, X isoform isoform 1 precursor
NM_182680 NP_872621 amelogenin, X isoform isoform 3 precursor
NM_182681 NP_872622 amelogenin, X isoform isoform 2 precursor


Homo sapiens (human) AMELX NP_872621.1
Macaca mulatta (Rhesus monkey) AMELX NP_001091983.1
Canis lupus familiaris (dog) AMELX XP_003435493.1
Bos taurus (cattle) AMELX NP_001014984.1
Rattus norvegicus (Norway rat) Amelx NP_062027.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AMELX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AMELX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu25376
XM_011545489 PREDICTED: Homo sapiens amelogenin, X-linked (AMELX), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu25531 NM_001142 Homo sapiens amelogenin, X-linked (AMELX), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu25376
NM_182680 Homo sapiens amelogenin, X-linked (AMELX), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu25363
NM_182681 Homo sapiens amelogenin, X-linked (AMELX), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu25376
Clone ID Related Accession (Same CDS sequence) NM_182680 , XM_011545489
Accession Version XM_011545489.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 618bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product amelogenin, X isoform isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTCTACCA 
CCTCATCCTG GGCACCCTGG TTATATCAAC TTCAGCTATG AGAACTCACA TTCTCAGGCT
ATCAATGTTG ACAGGACTGC ATTAGTGCTT ACCCCTTTGA AGTGGTACCA GAGCATAAGG
CCACCGTACC CTTCCTATGG TTACGAGCCC ATGGGTGGAT GGCTGCACCA CCAAATCATC
CCCGTGCTGT CCCAACAGCA CCCCCCGACT CACACCCTGC AGCCTCATCA CCACATCCCA
GTGGTGCCAG CTCAGCAGCC CGTGATCCCC CAGCAACCAA TGATGCCCGT TCCTGGCCAA
CACTCCATGA CTCCAATCCA ACACCACCAG CCAAACCTCC CTCCGCCCGC CCAGCAGCCC
TACCAGCCCC AGCCTGTTCA GCCACAGCCT CACCAGCCCA TGCAGCCCCA GCCACCTGTG
CACCCCATGC AGCCCCTGCC GCCACAGCCA CCTCTGCCTC CGATGTTCCC CATGCAGCCC
CTGCCTCCCA TGCTTCCTGA TCTGACTCTG GAAGCTTGGC CATCAACAGA CAAGACCAAG
CGGGAGGAAG TGGATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011543791.1
CDS219..836
Misc Feature(1)300..833(+)
Translation

Target ORF information:

RefSeq Version XM_011545489
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens amelogenin, X-linked (AMELX), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545489

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTCTACCA 
CCTCATCCTG GGCACCCTGG TTATATCAAC TTCAGCTATG AGAACTCACA TTCTCAGGCT
ATCAATGTTG ACAGGACTGC ATTAGTGCTT ACCCCTTTGA AGTGGTACCA GAGCATAAGG
CCACCGTACC CTTCCTATGG TTACGAGCCC ATGGGTGGAT GGCTGCACCA CCAAATCATC
CCCGTGCTGT CCCAACAGCA CCCCCCGACT CACACCCTGC AGCCTCATCA CCACATCCCA
GTGGTGCCAG CTCAGCAGCC CGTGATCCCC CAGCAACCAA TGATGCCCGT TCCTGGCCAA
CACTCCATGA CTCCAATCCA ACACCACCAG CCAAACCTCC CTCCGCCCGC CCAGCAGCCC
TACCAGCCCC AGCCTGTTCA GCCACAGCCT CACCAGCCCA TGCAGCCCCA GCCACCTGTG
CACCCCATGC AGCCCCTGCC GCCACAGCCA CCTCTGCCTC CGATGTTCCC CATGCAGCCC
CTGCCTCCCA TGCTTCCTGA TCTGACTCTG GAAGCTTGGC CATCAACAGA CAAGACCAAG
CGGGAGGAAG TGGATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25531
Clone ID Related Accession (Same CDS sequence) NM_001142
Accession Version NM_001142.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 576bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amelogenin, X isoform isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M86932.1. On Jan 19, 2000 this sequence version replaced gi:4502070. Transcript Variant: This variant (1) lacks an in-frame exon in the coding region, compared to variant 3. Isoform 1 is shorter than isoform 3 and is the most abundant isoform of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M86932.1, BC074951.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2148093 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTCTACCA 
CCTCATCCTG GGCACCCTGG TTATATCAAC TTCAGCTATG AGGTGCTTAC CCCTTTGAAG
TGGTACCAGA GCATAAGGCC ACCGTACCCT TCCTATGGTT ACGAGCCCAT GGGTGGATGG
CTGCACCACC AAATCATCCC CGTGCTGTCC CAACAGCACC CCCCGACTCA CACCCTGCAG
CCTCATCACC ACATCCCAGT GGTGCCAGCT CAGCAGCCCG TGATCCCCCA GCAACCAATG
ATGCCCGTTC CTGGCCAACA CTCCATGACT CCAATCCAAC ACCACCAGCC AAACCTCCCT
CCGCCCGCCC AGCAGCCCTA CCAGCCCCAG CCTGTTCAGC CACAGCCTCA CCAGCCCATG
CAGCCCCAGC CACCTGTGCA CCCCATGCAG CCCCTGCCGC CACAGCCACC TCTGCCTCCG
ATGTTCCCCA TGCAGCCCCT GCCTCCCATG CTTCCTGATC TGACTCTGGA AGCTTGGCCA
TCAACAGACA AGACCAAGCG GGAGGAAGTG GATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001133.1
CDS69..644
Misc Feature(1)42..44(+)
Misc Feature(2)150..641(+)
Exon (1)1..56
Gene:AMELX
Gene Synonym:
Exon (2)57..122
Gene:AMELX
Gene Synonym:
Exon (3)123..170
Gene:AMELX
Gene Synonym:
Exon (4)171..212
Gene:AMELX
Gene Synonym:
Exon (5)213..638
Gene:AMELX
Gene Synonym:
Exon (6)639..793
Gene:AMELX
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001142
Organism Homo sapiens (human)
Definition Homo sapiens amelogenin, X-linked (AMELX), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001142

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTCTACCA 
CCTCATCCTG GGCACCCTGG TTATATCAAC TTCAGCTATG AGGTGCTTAC CCCTTTGAAG
TGGTACCAGA GCATAAGGCC ACCGTACCCT TCCTATGGTT ACGAGCCCAT GGGTGGATGG
CTGCACCACC AAATCATCCC CGTGCTGTCC CAACAGCACC CCCCGACTCA CACCCTGCAG
CCTCATCACC ACATCCCAGT GGTGCCAGCT CAGCAGCCCG TGATCCCCCA GCAACCAATG
ATGCCCGTTC CTGGCCAACA CTCCATGACT CCAATCCAAC ACCACCAGCC AAACCTCCCT
CCGCCCGCCC AGCAGCCCTA CCAGCCCCAG CCTGTTCAGC CACAGCCTCA CCAGCCCATG
CAGCCCCAGC CACCTGTGCA CCCCATGCAG CCCCTGCCGC CACAGCCACC TCTGCCTCCG
ATGTTCCCCA TGCAGCCCCT GCCTCCCATG CTTCCTGATC TGACTCTGGA AGCTTGGCCA
TCAACAGACA AGACCAAGCG GGAGGAAGTG GATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25376
Clone ID Related Accession (Same CDS sequence) NM_182680 , XM_011545489
Accession Version NM_182680.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 618bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amelogenin, X isoform isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF436849.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (3) encodes the longest isoform (3) of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF436849.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2161674, SAMEA962333 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTCTACCA 
CCTCATCCTG GGCACCCTGG TTATATCAAC TTCAGCTATG AGAACTCACA TTCTCAGGCT
ATCAATGTTG ACAGGACTGC ATTAGTGCTT ACCCCTTTGA AGTGGTACCA GAGCATAAGG
CCACCGTACC CTTCCTATGG TTACGAGCCC ATGGGTGGAT GGCTGCACCA CCAAATCATC
CCCGTGCTGT CCCAACAGCA CCCCCCGACT CACACCCTGC AGCCTCATCA CCACATCCCA
GTGGTGCCAG CTCAGCAGCC CGTGATCCCC CAGCAACCAA TGATGCCCGT TCCTGGCCAA
CACTCCATGA CTCCAATCCA ACACCACCAG CCAAACCTCC CTCCGCCCGC CCAGCAGCCC
TACCAGCCCC AGCCTGTTCA GCCACAGCCT CACCAGCCCA TGCAGCCCCA GCCACCTGTG
CACCCCATGC AGCCCCTGCC GCCACAGCCA CCTCTGCCTC CGATGTTCCC CATGCAGCCC
CTGCCTCCCA TGCTTCCTGA TCTGACTCTG GAAGCTTGGC CATCAACAGA CAAGACCAAG
CGGGAGGAAG TGGATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_872621.1
CDS69..686
Misc Feature(1)42..44(+)
Misc Feature(2)150..683(+)
Exon (1)1..56
Gene:AMELX
Gene Synonym:
Exon (2)57..122
Gene:AMELX
Gene Synonym:
Exon (3)123..170
Gene:AMELX
Gene Synonym:
Exon (4)171..212
Gene:AMELX
Gene Synonym:
Exon (5)213..254
Gene:AMELX
Gene Synonym:
Exon (6)255..680
Gene:AMELX
Gene Synonym:
Exon (7)681..835
Gene:AMELX
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_182680
Organism Homo sapiens (human)
Definition Homo sapiens amelogenin, X-linked (AMELX), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_182680

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTCTACCA 
CCTCATCCTG GGCACCCTGG TTATATCAAC TTCAGCTATG AGAACTCACA TTCTCAGGCT
ATCAATGTTG ACAGGACTGC ATTAGTGCTT ACCCCTTTGA AGTGGTACCA GAGCATAAGG
CCACCGTACC CTTCCTATGG TTACGAGCCC ATGGGTGGAT GGCTGCACCA CCAAATCATC
CCCGTGCTGT CCCAACAGCA CCCCCCGACT CACACCCTGC AGCCTCATCA CCACATCCCA
GTGGTGCCAG CTCAGCAGCC CGTGATCCCC CAGCAACCAA TGATGCCCGT TCCTGGCCAA
CACTCCATGA CTCCAATCCA ACACCACCAG CCAAACCTCC CTCCGCCCGC CCAGCAGCCC
TACCAGCCCC AGCCTGTTCA GCCACAGCCT CACCAGCCCA TGCAGCCCCA GCCACCTGTG
CACCCCATGC AGCCCCTGCC GCCACAGCCA CCTCTGCCTC CGATGTTCCC CATGCAGCCC
CTGCCTCCCA TGCTTCCTGA TCTGACTCTG GAAGCTTGGC CATCAACAGA CAAGACCAAG
CGGGAGGAAG TGGATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25363
Clone ID Related Accession (Same CDS sequence) NM_182681
Accession Version NM_182681.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 528bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amelogenin, X isoform isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M86932.1. Transcript Variant: This variant (2) lacks two in-frame exons in the coding region, compared to variant 3. Isoform 2 is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M86932.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2161674 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTGTGCTT 
ACCCCTTTGA AGTGGTACCA GAGCATAAGG CCACCGTACC CTTCCTATGG TTACGAGCCC
ATGGGTGGAT GGCTGCACCA CCAAATCATC CCCGTGCTGT CCCAACAGCA CCCCCCGACT
CACACCCTGC AGCCTCATCA CCACATCCCA GTGGTGCCAG CTCAGCAGCC CGTGATCCCC
CAGCAACCAA TGATGCCCGT TCCTGGCCAA CACTCCATGA CTCCAATCCA ACACCACCAG
CCAAACCTCC CTCCGCCCGC CCAGCAGCCC TACCAGCCCC AGCCTGTTCA GCCACAGCCT
CACCAGCCCA TGCAGCCCCA GCCACCTGTG CACCCCATGC AGCCCCTGCC GCCACAGCCA
CCTCTGCCTC CGATGTTCCC CATGCAGCCC CTGCCTCCCA TGCTTCCTGA TCTGACTCTG
GAAGCTTGGC CATCAACAGA CAAGACCAAG CGGGAGGAAG TGGATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_872622.1
CDS69..596
Misc Feature(1)42..44(+)
Misc Feature(2)111..593(+)
Exon (1)1..56
Gene:AMELX
Gene Synonym:
Exon (2)57..122
Gene:AMELX
Gene Synonym:
Exon (3)123..164
Gene:AMELX
Gene Synonym:
Exon (4)165..590
Gene:AMELX
Gene Synonym:
Exon (5)591..745
Gene:AMELX
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_182681
Organism Homo sapiens (human)
Definition Homo sapiens amelogenin, X-linked (AMELX), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_182681

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGGGACCT GGATTTTATT TGCCTGCCTC CTGGGAGCAG CTTTTGCCAT GCCTGTGCTT 
ACCCCTTTGA AGTGGTACCA GAGCATAAGG CCACCGTACC CTTCCTATGG TTACGAGCCC
ATGGGTGGAT GGCTGCACCA CCAAATCATC CCCGTGCTGT CCCAACAGCA CCCCCCGACT
CACACCCTGC AGCCTCATCA CCACATCCCA GTGGTGCCAG CTCAGCAGCC CGTGATCCCC
CAGCAACCAA TGATGCCCGT TCCTGGCCAA CACTCCATGA CTCCAATCCA ACACCACCAG
CCAAACCTCC CTCCGCCCGC CCAGCAGCCC TACCAGCCCC AGCCTGTTCA GCCACAGCCT
CACCAGCCCA TGCAGCCCCA GCCACCTGTG CACCCCATGC AGCCCCTGCC GCCACAGCCA
CCTCTGCCTC CGATGTTCCC CATGCAGCCC CTGCCTCCCA TGCTTCCTGA TCTGACTCTG
GAAGCTTGGC CATCAACAGA CAAGACCAAG CGGGAGGAAG TGGATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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