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AATF cDNA ORF clone, Homo sapiens(Human)

Gene Symbol AATF
Entrez Gene ID 26574
Full Name apoptosis antagonizing transcription factor
Synonyms BFR2,CHE-1,CHE1,DED
General protein information
Preferred Names

apoptosis antagonizing transcription factor

Names

protein AATF
rb-binding protein Che-1

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

17

17q12

Summary The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008].
Disorder MIM:

608463


mRNA and Protein(s)

mRNA Protein Name
XM_011524611.1 XP_011522913.1 protein AATF isoform X1
NM_012138.3 NP_036270.1 protein AATF



Anopheles gambiae (African malaria mosquito) AgaP_AGAP007394 XP_308438.4
Caenorhabditis elegans (roundworm) Y73E7A.2 NP_490870.2
Oryza sativa (rice) Os01g0526200 NP_001043227.1
Xenopus tropicalis (tropical clawed frog) aatf NP_001016308.1
Canis lupus familiaris (dog) AATF XP_005624830.1
Mus musculus (house mouse) Aatf NP_062790.1
Danio rerio (zebrafish) aatf NP_001258768.1
Macaca mulatta (rhesus monkey) AATF XP_001109240.2
Pan troglodytes (chimpanzee) AATF XP_511427.2
Rattus norvegicus (Norway rat) Aatf NP_446172.1
Homo sapiens (human) AATF NP_036270.1
Bos taurus (cattle) AATF XP_002695664.3
Gallus gallus (chicken) AATF NP_001025895.1
Arabidopsis thaliana (thale cress) AT5G61330 NP_200941.2


Related articles in PubMed

Poly(ADP-ribosyl)ation of Apoptosis Antagonizing Transcription Factor Involved in Hydroquinone-Induced DNA Damage Response.
Ling XX, Liu JX, Yun L, DU YJ, Chen SQ, Chen JL, Tang HW, Liu LH
Biomedical and environmental sciences : BES29(1)80-4(2016 Jan)

Mitochondrial uncoupling protein (UCP2) gene expression is regulated by miR-2909.
Kaul D, Sharma S, Garg A
Blood cells, molecules & diseases55(1)89-93(2015 Jun)

Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53.
Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Gentileschi MP, Germoni S, Monteleone V, Pellegrino M, Kann M, De Meo PD, Pallocca M, Höpker K, Moretti F, Mattei E, Reinhardt HC, Floridi A, Passananti C, Benzing T, Blandino G, Fanciulli M
Cell death & disease6e1764(2015 May)

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Ponzoni M, Bossi G, Federico V, La Rosa F, Ricciardi MR, Lesma E, De Meo PD, Castrignanò T, Petrucci MT, Pisani F, Chesi M, Bergsagel PL, Floridi A, Tonon G, Passananti C, Blandino G, Fanciulli M
The EMBO journal34(9)1214-30(2015 May)

Oncogenic nature of a novel mutant AATF and its interactome existing within human cancer cells.
Sharma S, Kaul D, Arora M, Malik D
Cell biology international39(3)326-33(2015 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the effect of APOBEC3G over-expression upon AATF gene expression, was examined.
Title: APOBEC3G governs the generation of truncated AATF protein to ensure oncogenic transformation.

we identified the ANN complex as a novel functional module supporting the nucleolar maturation of 40S ribosomal subunits. Our data help to explain the described role of AATF in cell proliferation during mouse development as well as its requirement for malignant tumor growth.
Title: Human AATF/Che-1 forms a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis.

loss of Che-1 inhibits proliferation and promotes apoptosis in MG-63 cells by decreasing the level of mutant p53
Title: Che-1 gene silencing induces osteosarcoma cell apoptosis by inhibiting mutant p53 expression.

It was concluded that PARP-1 was involved in the DNA damage repair induced by HQ via increasing the accumulation of apoptosis antagonizing transcription factor through PARylation.
Title: Poly(ADP-ribosyl)ation of Apoptosis Antagonizing Transcription Factor Involved in Hydroquinone-Induced DNA Damage Response.

These results confirm Che-1 as an important regulator of p53 activity and suggest Che-1 to be a promising yet attractive drug target for cancer therapy.
Title: Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53.

The following AATF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AATF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu16451 NM_012138.3
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Homo sapiens apoptosis antagonizing transcription factor (AATF), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
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OHu66965 XM_011524611.1
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Homo sapiens apoptosis antagonizing transcription factor (AATF), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16451
Clone ID Related Accession (Same CDS sequence) NM_012138.3
Accession Version NM_012138.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1683bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-27
Organism Homo sapiens(Human)
Product protein AATF
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK057229.1, AF083208.1 and BC000591.2. On Sep 23, 2005 this sequence version replaced NM_012138.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK057229.1, SRR1803613.61371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
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361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCGGGGC CGCAGCCCCT GGCGCTGCAA CTGGAACAGT TGTTGAACCC GCGACCAAGC 
GAGGCGGACC CTGAAGCGGA CCCCGAGGAA GCCACTGCTG CCAGGGTGAT TGACAGGTTT
GATGAAGGGG AAGATGGGGA AGGTGATTTC CTAGTAGTGG GTAGCATTAG AAAACTGGCA
TCAGCCTCCC TCTTGGACAC GGACAAAAGG TATTGCGGCA AAACCACCTC TAGAAAAGCA
TGGAATGAAG ACCATTGGGA GCAGACTCTG CCAGGATCGT CTGATGAGGA AATATCTGAT
GAGGAAGGGT CTGGAGATGA AGATTCAGAG GGACTGGGTC TGGAGGAATA TGATGAGGAC
GACCTGGGTG CTGCTGAGGA ACAGGAGTGT GGTGATCACA GGGAGAGCAA GAAGAGCAGA
AGCCACTCTG CAAAAACACC GGGCTTCAGT GTCCAGAGTA TCAGTGACTT TGAGAAATTT
ACCAAGGGAA TGGATGACCT TGGGAGCAGT GAGGAGGAGG AAGACGAAGA GAGTGGCATG
GAAGAAGGGG ATGACGCGGA AGACTCCCAA GGCGAGAGTG AGGAAGACAG GGCTGGAGAT
AGAAACAGTG AGGATGATGG TGTGGTGATG ACCTTCTCTA GTGTCAAAGT TTCTGAGGAA
GTGGAGAAAG GAAGAGCCGT GAAGAACCAG ATAGCACTGT GGGACCAGCT CTTGGAAGGA
AGGATCAAAC TACAAAAAGC TCTGTTGACC ACCAACCAGC TTCCTCAACC AGATGTTTTC
CCATTGTTCA AGGACAAAGG TGGCCCAGAA TTTTCCAGTG CCCTGAAAAA TAGTCACAAG
GCACTTAAAG CATTGTTGAG GTCATTGGTA GGTCTTCAGG AAGAGTTGCT TTTCCAGTAC
CCAGACACTA GATATCTAGT AGATGGGACA AAGCCCAATG CGGGAAGTGA GGAGATTTCT
AGTGAAGATG ATGAGCTGGT AGAAGAGAAG AAGCAGCAAC GAAGAAGGGT CCCTGCAAAG
AGGAAGCTGG AGATGGAGGA CTATCCCAGC TTCATGGCAA AGCGCTTTGC CGACTTTACA
GTCTACAGGA ACCGCACACT TCAGAAATGG CACGATAAGA CCAAACTGGC TTCTGGAAAA
CTGGGGAAGG GTTTTGGTGC CTTTGAACGC TCAATCTTGA CTCAGATCGA CCATATTCTG
ATGGACAAAG AGAGATTACT TCGAAGGACA CAGACCAAGC GCTCTGTCTA TCGAGTTCTT
GGCAAACCTG AGCCAGCAGC TCAGCCTGTC CCAGAGAGTT TGCCAGGGGA ACCGGAGATC
CTTCCTCAAG CCCCTGCTAA TGCTCATCTG AAGGACTTGG ATGAAGAAAT CTTTGATGAT
GATGACTTTT ACCACCAGCT CCTTCGAGAA CTCATAGAAC GGAAGACCAG CTCCTTGGAT
CCCAACGATC AGGTGGCCAT GGGAAGGCAG TGGCTTGCAA TCCAGAAGTT ACGAAGCAAA
ATCCACAAAA AAGTAGATAG GAAAGCCAGC AAAGGCAGGA AACTTCGGTT TCATGTCCTT
AGCAAGCTAC TGAGTTTCAT GGCACCTATT GACCATACTA CAATGAATGA TGATGCCAGG
ACAGAACTGT ACCGCTCTCT TTTTGGCCAG CTCCACCCTC CCGACGAAGG CCACGGGGAT
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_036270.1
CDS252..1934
Misc Feature(1)255..257
Misc Feature(2)432..434
Misc Feature(3)438..440
Misc Feature(4)528..530
Misc Feature(5)531..533
Misc Feature(6)546..548
Misc Feature(7)561..563
Misc Feature(8)576..578
Misc Feature(9)600..602
Misc Feature(10)672..674
Misc Feature(11)699..701
Misc Feature(12)714..716
Misc Feature(13)858..860
Misc Feature(14)858..860
Misc Feature(15)912..1370
Misc Feature(16)1068..1196
Misc Feature(17)1068..1070
Misc Feature(18)1164..1166
Misc Feature(19)1179..1181
Misc Feature(20)1197..1367
Misc Feature(21)1197..1199
Misc Feature(22)1197..1199
Misc Feature(23)1209..1211
Misc Feature(24)1209..1211
Misc Feature(25)1212..1214
Misc Feature(26)1212..1214
Misc Feature(27)1368..1667
Misc Feature(28)1641..1895
Exon (1)1..342
Exon (2)343..534
Exon (3)535..945
Exon (4)946..1083
Exon (5)1084..1198
Exon (6)1199..1400
Exon (7)1401..1565
Exon (8)1566..1649
Exon (9)1650..1717
Exon (10)1718..1798
Exon (11)1799..1870
Exon (12)1871..2141
Translation

Target ORF information:

RefSeq Version NM_012138.3
Organism Homo sapiens(Human)
Definition Homo sapiens apoptosis antagonizing transcription factor (AATF), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_012138.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCGGGGC CGCAGCCCCT GGCGCTGCAA CTGGAACAGT TGTTGAACCC GCGACCAAGC 
GAGGCGGACC CTGAAGCGGA CCCCGAGGAA GCCACTGCTG CCAGGGTGAT TGACAGGTTT
GATGAAGGGG AAGATGGGGA AGGTGATTTC CTAGTAGTGG GTAGCATTAG AAAACTGGCA
TCAGCCTCCC TCTTGGACAC GGACAAAAGG TATTGCGGCA AAACCACCTC TAGAAAAGCA
TGGAATGAAG ACCATTGGGA GCAGACTCTG CCAGGATCGT CTGATGAGGA AATATCTGAT
GAGGAAGGGT CTGGAGATGA AGATTCAGAG GGACTGGGTC TGGAGGAATA TGATGAGGAC
GACCTGGGTG CTGCTGAGGA ACAGGAGTGT GGTGATCACA GGGAGAGCAA GAAGAGCAGA
AGCCACTCTG CAAAAACACC GGGCTTCAGT GTCCAGAGTA TCAGTGACTT TGAGAAATTT
ACCAAGGGAA TGGATGACCT TGGGAGCAGT GAGGAGGAGG AAGACGAAGA GAGTGGCATG
GAAGAAGGGG ATGACGCGGA AGACTCCCAA GGCGAGAGTG AGGAAGACAG GGCTGGAGAT
AGAAACAGTG AGGATGATGG TGTGGTGATG ACCTTCTCTA GTGTCAAAGT TTCTGAGGAA
GTGGAGAAAG GAAGAGCCGT GAAGAACCAG ATAGCACTGT GGGACCAGCT CTTGGAAGGA
AGGATCAAAC TACAAAAAGC TCTGTTGACC ACCAACCAGC TTCCTCAACC AGATGTTTTC
CCATTGTTCA AGGACAAAGG TGGCCCAGAA TTTTCCAGTG CCCTGAAAAA TAGTCACAAG
GCACTTAAAG CATTGTTGAG GTCATTGGTA GGTCTTCAGG AAGAGTTGCT TTTCCAGTAC
CCAGACACTA GATATCTAGT AGATGGGACA AAGCCCAATG CGGGAAGTGA GGAGATTTCT
AGTGAAGATG ATGAGCTGGT AGAAGAGAAG AAGCAGCAAC GAAGAAGGGT CCCTGCAAAG
AGGAAGCTGG AGATGGAGGA CTATCCCAGC TTCATGGCAA AGCGCTTTGC CGACTTTACA
GTCTACAGGA ACCGCACACT TCAGAAATGG CACGATAAGA CCAAACTGGC TTCTGGAAAA
CTGGGGAAGG GTTTTGGTGC CTTTGAACGC TCAATCTTGA CTCAGATCGA CCATATTCTG
ATGGACAAAG AGAGATTACT TCGAAGGACA CAGACCAAGC GCTCTGTCTA TCGAGTTCTT
GGCAAACCTG AGCCAGCAGC TCAGCCTGTC CCAGAGAGTT TGCCAGGGGA ACCGGAGATC
CTTCCTCAAG CCCCTGCTAA TGCTCATCTG AAGGACTTGG ATGAAGAAAT CTTTGATGAT
GATGACTTTT ACCACCAGCT CCTTCGAGAA CTCATAGAAC GGAAGACCAG CTCCTTGGAT
CCCAACGATC AGGTGGCCAT GGGAAGGCAG TGGCTTGCAA TCCAGAAGTT ACGAAGCAAA
ATCCACAAAA AAGTAGATAG GAAAGCCAGC AAAGGCAGGA AACTTCGGTT TCATGTCCTT
AGCAAGCTAC TGAGTTTCAT GGCACCTATT GACCATACTA CAATGAATGA TGATGCCAGG
ACAGAACTGT ACCGCTCTCT TTTTGGCCAG CTCCACCCTC CCGACGAAGG CCACGGGGAT
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu66965
Clone ID Related Accession (Same CDS sequence) XM_011524611.1
Accession Version XM_011524611.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1611bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product protein AATF isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCGGGGC CGCAGCCCCT GGCGCTGCAA CTGGAACAGT TGTTGAACCC GCGACCAAGC 
GAGGCGGACC CTGAAGCGGA CCCCGAGGAA GCCACTGCTG CCAGGGTGAT TGACAGGTTT
GATGAAGGGG AAGATGGGGA AGGTGATTTC CTAGTAGTGG GTAGCATTAG AAAACTGGCA
TCAGCCTCCC TCTTGGACAC GGACAAAAGG TATTGCGGCA AAACCACCTC TAGAAAAGCA
TGGAATGAAG ACCATTGGGA GCAGACTCTG CCAGGATCGT CTGATGAGGA AATATCTGAT
GAGGAAGGGT CTGGAGATGA AGATTCAGAG GGACTGGGTC TGGAGGAATA TGATGAGGAC
GACCTGGGTG CTGCTGAGGA ACAGGAGTGT GGTGATCACA GGGAGAGCAA GAAGAGCAGA
AGCCACTCTG CAAAAACACC GGGCTTCAGT GTCCAGAGTA TCAGTGACTT TGAGAAATTT
ACCAAGGGAA TGGATGACCT TGGGAGCAGT GAGGAGGAGG AAGACGAAGA GAGTGGCATG
GAAGAAGGGG ATGACGCGGA AGACTCCCAA GGCGAGAGTG AGGAAGACAG GGCTGGAGAT
AGAAACAGTG AGGATGATGG TGTGGTGATG ACCTTCTCTA GTGTCAAAGT TTCTGAGGAA
GTGGAGAAAG GAAGAGCCGT GAAGAACCAG ATAGCACTGT GGGACCAGCT CTTGGAAGGA
AGGATCAAAC TACAAAAAGC TCTGTTGACC ACCAACCAGC TTCCTCAACC AGATGTTTTC
CCATTGTTCA AGGACAAAGG TGGCCCAGAA TTTTCCAGTG CCCTGAAAAA TAGTCACAAG
GCACTTAAAG CATTGTTGAG GTCATTGGTA GGTCTTCAGG AAGAGTTGCT TTTCCAGTAC
CCAGACACTA GATATCTAGT AGATGGGACA AAGCCCAATG CGGGAAGTGA GGAGATTTCT
AGTGAAGATG ATGAGCTGGT AGAAGAGAAG AAGCAGCAAC GAAGAAGGGT CCCTGCAAAG
AGGAAGCTGG AGATGGAGGA CTATCCCAGC TTCATGGCAA AGCGCTTTGC CGACTTTACA
GTCTACAGGA ACCGCACACT TCAGAAATGG CACGATAAGA CCAAACTGGC TTCTGGAAAA
CTGGGGAAGG GTTTTGGTGC CTTTGAACGC TCAATCTTGA CTCAGATCGA CCATATTCTG
ATGGACAAAG AGAGATTACT TCGAAGGACA CAGACCAAGC GCTCTGTCTA TCGAGTTCTT
GGCAAACCTG AGCCAGCAGC TCAGCCTGTC CCAGAGAGTT TGCCAGGGGA ACCGGAGATC
CTTCCTCAAG CCCCTGCTAA TGCTCATCTG AAGGACTTGG ATGAAGAAAT CTTTGATGAT
GATGACTTTT ACCACCAGCT CCTTCGAGAA CTCATAGAAC GGAAGACCAG CTCCTTGGAT
CCCAACGATC AGGTGGCCAT GGGAAGGCAG TGGCTTGCAA TCCAGAAGTT ACGAAGCAAA
ATCCACAAAA AAGTAGATAG GAAAGCCAGC AAAGGCAGGA AACTTCGGAC AGAACTGTAC
CGCTCTCTTT TTGGCCAGCT CCACCCTCCC GACGAAGGCC ACGGGGATTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011522913.1
CDS236..1846
Misc Feature(1)896..1354
Misc Feature(2)1625..1807
Translation

Target ORF information:

RefSeq Version XM_011524611.1
Organism Homo sapiens(Human)
Definition Homo sapiens apoptosis antagonizing transcription factor (AATF), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011524611.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCGGGGC CGCAGCCCCT GGCGCTGCAA CTGGAACAGT TGTTGAACCC GCGACCAAGC 
GAGGCGGACC CTGAAGCGGA CCCCGAGGAA GCCACTGCTG CCAGGGTGAT TGACAGGTTT
GATGAAGGGG AAGATGGGGA AGGTGATTTC CTAGTAGTGG GTAGCATTAG AAAACTGGCA
TCAGCCTCCC TCTTGGACAC GGACAAAAGG TATTGCGGCA AAACCACCTC TAGAAAAGCA
TGGAATGAAG ACCATTGGGA GCAGACTCTG CCAGGATCGT CTGATGAGGA AATATCTGAT
GAGGAAGGGT CTGGAGATGA AGATTCAGAG GGACTGGGTC TGGAGGAATA TGATGAGGAC
GACCTGGGTG CTGCTGAGGA ACAGGAGTGT GGTGATCACA GGGAGAGCAA GAAGAGCAGA
AGCCACTCTG CAAAAACACC GGGCTTCAGT GTCCAGAGTA TCAGTGACTT TGAGAAATTT
ACCAAGGGAA TGGATGACCT TGGGAGCAGT GAGGAGGAGG AAGACGAAGA GAGTGGCATG
GAAGAAGGGG ATGACGCGGA AGACTCCCAA GGCGAGAGTG AGGAAGACAG GGCTGGAGAT
AGAAACAGTG AGGATGATGG TGTGGTGATG ACCTTCTCTA GTGTCAAAGT TTCTGAGGAA
GTGGAGAAAG GAAGAGCCGT GAAGAACCAG ATAGCACTGT GGGACCAGCT CTTGGAAGGA
AGGATCAAAC TACAAAAAGC TCTGTTGACC ACCAACCAGC TTCCTCAACC AGATGTTTTC
CCATTGTTCA AGGACAAAGG TGGCCCAGAA TTTTCCAGTG CCCTGAAAAA TAGTCACAAG
GCACTTAAAG CATTGTTGAG GTCATTGGTA GGTCTTCAGG AAGAGTTGCT TTTCCAGTAC
CCAGACACTA GATATCTAGT AGATGGGACA AAGCCCAATG CGGGAAGTGA GGAGATTTCT
AGTGAAGATG ATGAGCTGGT AGAAGAGAAG AAGCAGCAAC GAAGAAGGGT CCCTGCAAAG
AGGAAGCTGG AGATGGAGGA CTATCCCAGC TTCATGGCAA AGCGCTTTGC CGACTTTACA
GTCTACAGGA ACCGCACACT TCAGAAATGG CACGATAAGA CCAAACTGGC TTCTGGAAAA
CTGGGGAAGG GTTTTGGTGC CTTTGAACGC TCAATCTTGA CTCAGATCGA CCATATTCTG
ATGGACAAAG AGAGATTACT TCGAAGGACA CAGACCAAGC GCTCTGTCTA TCGAGTTCTT
GGCAAACCTG AGCCAGCAGC TCAGCCTGTC CCAGAGAGTT TGCCAGGGGA ACCGGAGATC
CTTCCTCAAG CCCCTGCTAA TGCTCATCTG AAGGACTTGG ATGAAGAAAT CTTTGATGAT
GATGACTTTT ACCACCAGCT CCTTCGAGAA CTCATAGAAC GGAAGACCAG CTCCTTGGAT
CCCAACGATC AGGTGGCCAT GGGAAGGCAG TGGCTTGCAA TCCAGAAGTT ACGAAGCAAA
ATCCACAAAA AAGTAGATAG GAAAGCCAGC AAAGGCAGGA AACTTCGGAC AGAACTGTAC
CGCTCTCTTT TTGGCCAGCT CCACCCTCCC GACGAAGGCC ACGGGGATTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Poly(ADP-ribosyl)ation of Apoptosis Antagonizing Transcription Factor Involved in Hydroquinone-Induced DNA Damage Response.
Biomedical and environmental sciences : BES29(1)80-4(2016 Jan)
Ling XX,Liu JX,Yun L,DU YJ,Chen SQ,Chen JL,Tang HW,Liu LH


book

Mitochondrial uncoupling protein (UCP2) gene expression is regulated by miR-2909.
Blood cells, molecules & diseases55(1)89-93(2015 Jun)
Kaul D,Sharma S,Garg A


book

Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53.
Cell death & disease6e1764(2015 May)
Desantis A,Bruno T,Catena V,De Nicola F,Goeman F,Iezzi S,Sorino C,Gentileschi MP,Germoni S,Monteleone V,Pellegrino M,Kann M,De Meo PD,Pallocca M,Höpker K,Moretti F,Mattei E,Reinhardt HC,Floridi A,Passananti C,Benzing T,Blandino G,Fanciulli M


book

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
The EMBO journal34(9)1214-30(2015 May)
Desantis A,Bruno T,Catena V,De Nicola F,Goeman F,Iezzi S,Sorino C,Ponzoni M,Bossi G,Federico V,La Rosa F,Ricciardi MR,Lesma E,De Meo PD,Castrignanò T,Petrucci MT,Pisani F,Chesi M,Bergsagel PL,Floridi A,Tonon G,Passananti C,Blandino G,Fanciulli M


book

Oncogenic nature of a novel mutant AATF and its interactome existing within human cancer cells.
Cell biology international39(3)326-33(2015 Mar)
Sharma S,Kaul D,Arora M,Malik D


 
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