BEX3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	BEX3
Entrez Gene ID	27018
Full Name	brain expressed X-linked 3
Synonyms	Bex,DXS6984E,HGR74,NADE,NGFRAP1
General protein information	Preferred Names brain expressed X-linked 3 Names protein BEX3 brain-expressed X-linked protein 3 nerve growth factor receptor (TNFRSF16) associated protein 1 ovarian granulosa cell 13.0 kDa protein HGR74 p75NTR-associated cell death executor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq22.2
Disorder MIM:	300361

mRNA and Protein(s)

mRNA	Protein	Name
NM_014380.2	NP_055195.1	protein BEX3 isoform b
NM_206917.2	NP_996800.1	protein BEX3 isoform a
NM_014380.3	NP_055195.1	protein BEX3 isoform b
NM_206917.3	NP_996800.1	protein BEX3 isoform a
NM_206915.2	NP_996798.1	protein BEX3 isoform b
NM_001282674.1	NP_001269603.1	protein BEX3 isoform c

Pathways from BioSystems

Homologies

Homo sapiens (human)	NGFRAP1	NP_001269603.1
	NGFRAP1	XP_002806383.1
Mus musculus (house mouse)	Ngfrap1	NP_033880.1
Canis lupus familiaris (dog)	NGFRAP1	XP_003435675.1
Pan troglodytes (chimpanzee)	NGFRAP1	XP_001136975.1
Bos taurus (cattle)	NGFRAP1	NP_001157249.1

Gene Ontology
Bibliography

Related articles in PubMed

BEX3 contributes to cisplatin chemoresistance in nasopharyngeal carcinoma.
Gao W, Li JZ, Chen SQ, Chu CY, Chan JY, Wong TS
Cancer medicine6(2)439-451(2017 Feb)

Next-generation sequencing to generate interactome datasets.
Yu H, Tardivo L, Tam S, Weiner E, Gebreab F, Fan C, Svrzikapa N, Hirozane-Kishikawa T, Rietman E, Yang X, Sahalie J, Salehi-Ashtiani K, Hao T, Cusick ME, Hill DE, Roth FP, Braun P, Vidal M
Nature methods8(6)478-80(2011 Jun)

The TSC1 gene product hamartin interacts with NADE.
Yasui S, Tsuzaki K, Ninomiya H, Floricel F, Asano Y, Maki H, Takamura A, Nanba E, Higaki K, Ohno K
Molecular and cellular neurosciences35(1)100-8(2007 May)

Characterization of human dopamine responsive protein DRG-1 that binds to p75NTR-associated cell death executor NADE.
Yu Y, Wang J, Yuan H, Qin F, Wang J, Zhang N, Li YY, Liu J, Lu H
Brain research1100(1)13-20(2006 Jul)

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.
Winter EE, Ponting CP
BMC evolutionary biology554(2005 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results showed that BEX3 was overexpressed in nasopharyngeal carcinoma (NPC), and indicated a unique functional role of BEX3 in mediating the sensitivity of NPC cells to cisplatin.
Title: BEX3 contributes to cisplatin chemoresistance in nasopharyngeal carcinoma.

DRG-1 may contribute to the dopamine-induced cell growth, which is negatively regulated by NADE
Title: Characterization of human dopamine responsive protein DRG-1 that binds to p75NTR-associated cell death executor NADE.

suppresses cell growth in vivo, when expressed in cultured cells
Title: NADE (p75NTR-associated cell death executor) suppresses cellular growth in vivo.

Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis
Title: Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis.

The following BEX3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BEX3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14195	NM_014380.3 Latest version!	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14195	NM_206915.2 Latest version!	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14678	NM_206917.3 Latest version!	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14805	NM_001282674.1 Latest version!	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu14195	NM_014380.2	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14678	NM_206917.2	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BEX3 ( NM_014380.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055195.1 Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu14195
Clone ID Related Accession (Same CDS sequence)	NM_014380.2 , NM_014380.3 , NM_206915.2
Accession Version	NM_014380.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	protein BEX3 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from M38188.1 and BQ068114.1. On Sep 17, 2013 this sequence version replaced NM_014380.1. Transcript Variant: This variant (3) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a longer N-terminus than isoform a. Variants 2 and 3 encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055195.1
CDS	312..647
Translation	MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_014380.2
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014380.2

ORF Insert Sequence:

ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEX3 ( NM_014380.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055195.1 Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 3, mRNA.

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CloneID	OHu14195
Clone ID Related Accession (Same CDS sequence)	NM_014380.2 , NM_014380.3 , NM_206915.2
Accession Version	NM_014380.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-06
Organism	Homo sapiens(human)
Product	protein BEX3 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606763.6, M38188.1 and BQ068114.1. On Jun 2, 2019 this sequence version replaced NM_014380.2. Transcript Variant: This variant (3) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a longer N-terminus than isoform a. Variants 2 and 3 encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: SRR7410571.180508.1, SRR7410570.691750.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055195.1
CDS	455..790
Translation	MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_014380.3
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014380.3

ORF Insert Sequence:

ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEX3 ( NM_206915.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_996798.1 Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14195
Clone ID Related Accession (Same CDS sequence)	NM_014380.2 , NM_014380.3 , NM_206915.2
Accession Version	NM_206915.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	protein BEX3 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606763.6, CD048295.1, AK057859.1, BC003190.1 and BQ068114.1. On Sep 17, 2013 this sequence version replaced NM_206915.1. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a longer N-terminus than isoform a. Variants 2 and 3 encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY833562.1, BC003190.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996798.1
CDS	400..735
Translation	MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_206915.2
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206915.2

ORF Insert Sequence:

ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEX3 ( NM_206917.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_996800.1 Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14678
Clone ID Related Accession (Same CDS sequence)	NM_206917.2 , NM_206917.3
Accession Version	NM_206917.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 306bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	protein BEX3 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606763.6, CD048295.1, AK057859.1 and BQ068114.1. On Sep 17, 2013 this sequence version replaced NM_206917.1. Transcript Variant: This variant (1) encodes the shortest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD048295.1, ERR279849.3574.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC CTATGCAGAA TGGAGAGGAA GACCGCCCTT TGGGAGGAGG TGAAGGCCAC 
CAGCCTGCAG GAAATCGACG GGGACAGGCT CGCCGACTTG CCCCTAATTT TCGATGGGCC 
ATACCCAATA GGCAGATCAA TGATGGGATG GGTGGAGATG GAGATGATAT GGAAATATTC 
ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA CTTAGGGAGC TGCAGTTGAG GAATTGTCTG 
CGTATCCTTA TGGGGGAGCT CTCTAATCAC CATGACCATC ATGATGAATT TTGCCTTATG 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996800.1
CDS	383..688
Translation	MEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_206917.2
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206917.2

ORF Insert Sequence:

ATGGAGCAGC CTATGCAGAA TGGAGAGGAA GACCGCCCTT TGGGAGGAGG TGAAGGCCAC 
CAGCCTGCAG GAAATCGACG GGGACAGGCT CGCCGACTTG CCCCTAATTT TCGATGGGCC 
ATACCCAATA GGCAGATCAA TGATGGGATG GGTGGAGATG GAGATGATAT GGAAATATTC 
ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA CTTAGGGAGC TGCAGTTGAG GAATTGTCTG 
CGTATCCTTA TGGGGGAGCT CTCTAATCAC CATGACCATC ATGATGAATT TTGCCTTATG 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEX3 ( NM_206917.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_996800.1 Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14678
Clone ID Related Accession (Same CDS sequence)	NM_206917.2 , NM_206917.3
Accession Version	NM_206917.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 306bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-30
Organism	Homo sapiens(human)
Product	protein BEX3 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK057859.1 and BQ068114.1. On Aug 31, 2019 this sequence version replaced NM_206917.2. Transcript Variant: This variant (1) encodes the shortest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ068114.1, AL703319.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC CTATGCAGAA TGGAGAGGAA GACCGCCCTT TGGGAGGAGG TGAAGGCCAC 
CAGCCTGCAG GAAATCGACG GGGACAGGCT CGCCGACTTG CCCCTAATTT TCGATGGGCC 
ATACCCAATA GGCAGATCAA TGATGGGATG GGTGGAGATG GAGATGATAT GGAAATATTC 
ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA CTTAGGGAGC TGCAGTTGAG GAATTGTCTG 
CGTATCCTTA TGGGGGAGCT CTCTAATCAC CATGACCATC ATGATGAATT TTGCCTTATG 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996800.1
CDS	168..473
Translation	MEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_206917.3
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206917.3

ORF Insert Sequence:

ATGGAGCAGC CTATGCAGAA TGGAGAGGAA GACCGCCCTT TGGGAGGAGG TGAAGGCCAC 
CAGCCTGCAG GAAATCGACG GGGACAGGCT CGCCGACTTG CCCCTAATTT TCGATGGGCC 
ATACCCAATA GGCAGATCAA TGATGGGATG GGTGGAGATG GAGATGATAT GGAAATATTC 
ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA CTTAGGGAGC TGCAGTTGAG GAATTGTCTG 
CGTATCCTTA TGGGGGAGCT CTCTAATCAC CATGACCATC ATGATGAATT TTGCCTTATG 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEX3 ( NM_001282674.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269603.1 Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu14805
Clone ID Related Accession (Same CDS sequence)	NM_001282674.1
Accession Version	NM_001282674.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-15
Organism	Homo sapiens(human)
Product	protein BEX3 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606763.6, CD048295.1, AI929106.1, AK057859.1 and BQ068114.1. On Sep 17, 2013 this sequence version replaced XM_005262120.1. Transcript Variant: This variant (4) lacks an exon, uses an alternate internal splice site, and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (c) has a longer N-terminus than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BE896163.1, AI929106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGG CGGGTGGGGG GAAGGGGGAG ATCCTGCTGC ACTGGCCGCC CAAGTTGGGG 
GGCGAGCTCG GTGGTGACGC GCGGCCCTCA CGTGACCCAG AGCTGCAGAG CGACGCAGCC 
TTCGGTGCAG TCGTCACTCG CGTCTGGCTA CCAGCTCCCC GCTGCCCTGA GCTCGGCGGG 
CTGGCATTCG GCCCGGGGAA AAGCGGAGCA GAAAAACAAC CAGAAAAAAA AAATCTCATC 
ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269603.1
CDS	81..656
Translation	MAVAGGGKGEILLHWPPKLGGELGGDARPSRDPELQSDAAFGAVVTRVWLPAPRCPELGGLAFGPGKSGAEKQPEKKNLIMANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_001282674.1
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 3 (BEX3), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282674.1

ORF Insert Sequence:

ATGGCGGTGG CGGGTGGGGG GAAGGGGGAG ATCCTGCTGC ACTGGCCGCC CAAGTTGGGG 
GGCGAGCTCG GTGGTGACGC GCGGCCCTCA CGTGACCCAG AGCTGCAGAG CGACGCAGCC 
TTCGGTGCAG TCGTCACTCG CGTCTGGCTA CCAGCTCCCC GCTGCCCTGA GCTCGGCGGG 
CTGGCATTCG GCCCGGGGAA AAGCGGAGCA GAAAAACAAC CAGAAAAAAA AAATCTCATC 
ATGGCAAATA TTCACCAGGA AAACGAAGAG ATGGAGCAGC CTATGCAGAA TGGAGAGGAA 
GACCGCCCTT TGGGAGGAGG TGAAGGCCAC CAGCCTGCAG GAAATCGACG GGGACAGGCT 
CGCCGACTTG CCCCTAATTT TCGATGGGCC ATACCCAATA GGCAGATCAA TGATGGGATG 
GGTGGAGATG GAGATGATAT GGAAATATTC ATGGAGGAGA TGAGAGAAAT CAGAAGAAAA 
CTTAGGGAGC TGCAGTTGAG GAATTGTCTG CGTATCCTTA TGGGGGAGCT CTCTAATCAC 
CATGACCATC ATGATGAATT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BEX3 contributes to cisplatin chemoresistance in nasopharyngeal carcinoma.
Cancer medicine6(2)439-451(2017 Feb)
Gao W,Li JZ,Chen SQ,Chu CY,Chan JY,Wong TS

Next-generation sequencing to generate interactome datasets.
Nature methods8(6)478-80(2011 Jun)
Yu H,Tardivo L,Tam S,Weiner E,Gebreab F,Fan C,Svrzikapa N,Hirozane-Kishikawa T,Rietman E,Yang X,Sahalie J,Salehi-Ashtiani K,Hao T,Cusick ME,Hill DE,Roth FP,Braun P,Vidal M

The TSC1 gene product hamartin interacts with NADE.
Molecular and cellular neurosciences35(1)100-8(2007 May)
Yasui S,Tsuzaki K,Ninomiya H,Floricel F,Asano Y,Maki H,Takamura A,Nanba E,Higaki K,Ohno K

Characterization of human dopamine responsive protein DRG-1 that binds to p75NTR-associated cell death executor NADE.
Brain research1100(1)13-20(2006 Jul)
Yu Y,Wang J,Yuan H,Qin F,Wang J,Zhang N,Li YY,Liu J,Lu H

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.
BMC evolutionary biology554(2005 Oct)
Winter EE,Ponting CP

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BEX3 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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