Gene Symbol | DAPP1 |
Entrez Gene ID | 27071 |
Full Name | dual adaptor of phosphotyrosine and 3-phosphoinositides 1 |
Synonyms | BAM32 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » DAPP1 cDNA ORF clone
Gene Symbol | DAPP1 |
Entrez Gene ID | 27071 |
Full Name | dual adaptor of phosphotyrosine and 3-phosphoinositides 1 |
Synonyms | BAM32 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_017008024.1 | XP_016863513.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X2 |
NM_001306151.2 | NP_001293080.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 2 |
NM_014395.3 | NP_055210.2 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 1 |
XM_011531840.2 | XP_011530142.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X1 |
XM_011531843.3 | XP_011530145.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X3 |
NM_001306151.1 | NP_001293080.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 2 |
XM_011531843.2 | XP_011530145.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X3 |
XM_011531842.1 | XP_011530144.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X2 |
NM_014395.2 | NP_055210.2 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 1 |
XM_017008023.1 | XP_016863512.1 | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X2 |
Pan troglodytes (chimpanzee) | DAPP1 | XP_517361.2 |
Canis lupus familiaris (dog) | DAPP1 | XP_535669.2 |
Bos taurus (cattle) | DAPP1 | NP_001070359.1 |
Gallus gallus (chicken) | DAPP1 | NP_001012951.2 |
Danio rerio (zebrafish) | dapp1 | NP_001017691.1 |
Xenopus tropicalis (tropical clawed frog) | dapp1 | NP_001015723.1 |
Mus musculus (house mouse) | Dapp1 | NP_036062.1 |
Homo sapiens (human) | DAPP1 | NP_055210.2 |
DAPP1 | XP_001107831.2 | |
Rattus norvegicus (Norway rat) | Dapp1 | NP_001102038.1 |
Phospho-tyrosine dependent protein-protein interaction network.
Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U
Molecular systems biology11(3)794(2015 Mar)
The adaptor protein Bam32 in human dendritic cells participates in the regulation of MHC class I-induced CD8+ T cell activation.
Ortner D, Grabher D, Hermann M, Kremmer E, Hofer S, Heufler C
Journal of immunology (Baltimore, Md. : 1950)187(8)3972-8(2011 Oct)
Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains.
Manna D, Albanese A, Park WS, Cho W
The Journal of biological chemistry282(44)32093-105(2007 Nov)
The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization.
Niiro H, Allam A, Stoddart A, Brodsky FM, Marshall AJ, Clark EA
Journal of immunology (Baltimore, Md. : 1950)173(9)5601-9(2004 Nov)
The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism.
Allam A, Niiro H, Clark EA, Marshall AJ
The Journal of biological chemistry279(38)39775-82(2004 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8(+) T cell activation.
Title: The adaptor protein Bam32 in human dendritic cells participates in the regulation of MHC class I-induced CD8+ T cell activation.
BAM32 works downstream of Src family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells.
Title: The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization.
novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling.
Title: The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism.
The following DAPP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DAPP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu29922 | |
Clone ID Related Accession (Same CDS sequence) | NM_014395.3 , NM_014395.2 | |
Accession Version | NM_014395.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-25 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN995752.1, AF163254.1, BC012924.1, BM968883.1 and CA428013.1. On Nov 22, 2018 this sequence version replaced NM_014395.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.261143.1, SRR1660803.51428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000512369.2/ ENSP00000423602.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_055210.2 |
CDS | 88..930 |
Translation |
Target ORF information:
Target ORF information:
|
NM_014395.3 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu29922 | |
Clone ID Related Accession (Same CDS sequence) | NM_014395.3 , NM_014395.2 | |
Accession Version | NM_014395.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN995752.1, AF163254.1, BC012924.1, BM968883.1 and CA428013.1. On Oct 24, 2007 this sequence version replaced NM_014395.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.261143.1, SRR1660803.51428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_055210.2 |
CDS | 91..933 |
Translation |
Target ORF information:
Target ORF information:
|
NM_014395.2 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67042 | |
Clone ID Related Accession (Same CDS sequence) | XM_011531843.3 , XM_011531843.2 | |
Accession Version | XM_011531843.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011531843.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTTCTAA AACATCCCTA CCCAAGAAAA GTGGAAGAAC CCTCCATTTA TGAATCTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011530145.1 |
CDS | 247..723 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011531843.3 |
1 | ATGGTTCTAA AACATCCCTA CCCAAGAAAA GTGGAAGAAC CCTCCATTTA TGAATCTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67042 | |
Clone ID Related Accession (Same CDS sequence) | XM_011531843.3 , XM_011531843.2 | |
Accession Version | XM_011531843.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011531843.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTTCTAA AACATCCCTA CCCAAGAAAA GTGGAAGAAC CCTCCATTTA TGAATCTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011530145.1 |
CDS | 246..722 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011531843.2 |
1 | ATGGTTCTAA AACATCCCTA CCCAAGAAAA GTGGAAGAAC CCTCCATTTA TGAATCTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67043 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306151.2 , NM_001306151.1 | |
Accession Version | NM_001306151.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-27 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP001962.2, AF186022.1, BC012924.1 and CA428013.1. On May 31, 2019 this sequence version replaced NM_001306151.1. Transcript Variant: This variant (2) differs in the 3' UTR and uses an alternate exon that causes a frameshift in the 3' coding region compared to variant 1. It encodes isoform 2, which is shorter and has a novel C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF186022.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293080.1 |
CDS | 88..879 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306151.2 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67043 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306151.2 , NM_001306151.1 | |
Accession Version | NM_001306151.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-24 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF186022.1, AP001962.2, BC012924.1 and CA428013.1. On Apr 15, 2015 this sequence version replaced XM_011531841.1. Transcript Variant: This variant (2) differs in the 3' UTR and uses an alternate exon that causes a frameshift in the 3' coding region compared to variant 1. It encodes isoform 2, which is shorter and has a novel C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF186022.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293080.1 |
CDS | 82..873 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306151.1 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67040 | |
Clone ID Related Accession (Same CDS sequence) | XM_011531840.2 | |
Accession Version | XM_011531840.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011531840.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011530142.1 |
CDS | 85..888 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011531840.2 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67041 | |
Clone ID Related Accession (Same CDS sequence) | XM_017008024.1 , XM_011531842.1 , XM_017008023.1 | |
Accession Version | XM_017008024.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016863513.1 |
CDS | 85..861 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017008024.1 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67041 | |
Clone ID Related Accession (Same CDS sequence) | XM_017008024.1 , XM_011531842.1 , XM_017008023.1 | |
Accession Version | XM_011531842.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011530144.1 |
CDS | 85..861 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011531842.1 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu67041 | |
Clone ID Related Accession (Same CDS sequence) | XM_017008024.1 , XM_011531842.1 , XM_017008023.1 | |
Accession Version | XM_017008023.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016863512.1 |
CDS | 85..861 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017008023.1 |
1 | ATGGGCAGAG CAGAACTTCT AGAAGGGAAG ATGAGCACCC AGGATCCCTC AGATCTGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Phospho-tyrosine dependent protein-protein interaction network. |
The adaptor protein Bam32 in human dendritic cells participates in the regulation of MHC class I-induced CD8+ T cell activation. |
Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains. |
The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization. |
The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism. |