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APC cDNA ORF clone, Homo sapiens(Human)

Gene Symbol APC
Entrez Gene ID 324
Full Name APC, WNT signaling pathway regulator
Synonyms BTPS2,DP2,DP2.5,DP3,GS,PPP1R46
General protein information
Preferred Names

APC, WNT signaling pathway regulator

Names

adenomatous polyposis coli protein
WNT signaling pathway regulator
adenomatosis polyposis coli tumor suppressor
deleted in polyposis 2.5
protein phosphatase 1, regulatory subunit 46
truncated adenomatosis polyposis coli

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

5

5q22.2

Summary This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008].
Disorder MIM:

611731

Disorder Html: Adenomatous polyposis coli, 175100 (3); Gastric cancer, somatic,

mRNA and Protein(s)

mRNA Protein Name
NM_001127511.2 NP_001120983.2 adenomatous polyposis coli protein isoform a
NM_001127510.2 NP_001120982.1 adenomatous polyposis coli protein isoform b
NM_000038.5 NP_000029.2 adenomatous polyposis coli protein isoform b



Canis lupus familiaris (dog) APC XP_005618091.1
Gallus gallus (chicken) APC XP_004949340.1
Danio rerio (zebrafish) apc NP_001137312.1
Homo sapiens (human) APC NP_001120982.1
Bos taurus (cattle) APC NP_001069454.2
Mus musculus (house mouse) Apc NP_031488.2
Rattus norvegicus (Norway rat) Apc NP_036631.1
Xenopus tropicalis (tropical clawed frog) apc XP_004910521.1
Pan troglodytes (chimpanzee) APC XP_001143965.1


Related articles in PubMed

Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer.
Zhang L, Shay JW
Journal of the National Cancer Institute109(8)(2017 08)

Molecular clonality analysis of esophageal adenocarcinoma by multiregion sequencing of tumor samples.
van Nistelrooij AM, van Marion R, Koppert LB, Biermann K, Spaander MC, Tilanus HW, van Lanschot JJ, Wijnhoven BP, Dinjens WN
BMC research notes10(1)144(2017 Apr)

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Gao FJ, Shi L, Hines T, Hebbar S, Neufeld KL, Smith DS
Molecular biology of the cell28(5)587-599(2017 Mar)

Identification of an alternative 5' untranslated region of the adenomatous polyposis coli gene.
Lambertz S, Ballhausen WG
Human genetics90(6)650-2(1993 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our study showed that mutations in the APC gene alter the protein expression and cell cycle regulation in diffuse type gastric adenocarcinoma.
Title: Novel APC gene mutations associated with protein alteration in diffuse type gastric cancer.

The rs75612255 C allele and rs113017087 C allele in promoter 1A of APC as well as the rs138386816 T allele and rs115658307 T allele in promoter 1B of APC significantly increased luciferase activity in the human erythromyeloblastoid leukaemia cell line K562.
Title: Regulatory single nucleotide polymorphisms (rSNPs) at the promoters 1A and 1B of the human APC gene.

AXIN1 is expressed in meningioma along with APC and E-cadherin
Title: AXIN1 Expression and Localization in Meningiomas and Association to Changes of APC and E-cadherin.

Both TIMP3 and APC methylation were associated with lymph node metastasis and higher clinical stage of tumors. Patients with methylation at TIMP3 or APC had worse prognoses as compared to those without these alterations.
Title: Characterization of gene methylation in human papillomavirus associated-head and neck squamous cell carcinoma.

The present findings indicate epigenetic silencing of APC in advanced gallbladder cancer (GBC). The methylation pattern, followed by expression analysis of APC may be suggested for diagnostic, prognostic and therapeutic purposes in GBC in future
Title: Epigenetic regulation of

The following APC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu16786 NM_001127510.2
Latest version!
Homo sapiens APC, WNT signaling pathway regulator (APC), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 24 $923.30
$1319.00
OHu16786 NM_000038.5
Latest version!
Homo sapiens APC, WNT signaling pathway regulator (APC), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 24 $923.30
$1319.00
OHu16843 NM_001127511.2
Latest version!
Homo sapiens APC, WNT signaling pathway regulator (APC), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $923.30
$1319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16786
Clone ID Related Accession (Same CDS sequence) NM_001127510.2 , NM_000038.5
Accession Version NM_001127510.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 8532bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product adenomatous polyposis coli protein isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA795663.1, AB210001.1 and CA313732.1. On Sep 17, 2010 this sequence version replaced NM_001127510.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also contains an alternate in-frame exon compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a. Variants 2 and 3 encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB210001.1, SRR1803615.13317.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMN03465402 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001120982.1
CDS194..8725
Misc Feature(1)185..187
Misc Feature(2)197..199
Misc Feature(3)203..358
Misc Feature(4)512..514
Misc Feature(5)524..526
Misc Feature(6)572..814
Misc Feature(7)1124..1432
Misc Feature(8)1550..1678
Misc Feature(9)1583..1984
Misc Feature(10)1586..1717
Misc Feature(11)order(1688..1690,1700..1702,1712..1714,1808..1810,1820..1822,1829..1831,1841..1843,1952..1954,1961..1963,1970..1975,1982..1984)
Misc Feature(12)order(1688..1690,1700..1702,1712..1714,1817..1819,1829..1831,1841..1843,1949..1951,1961..1963,1973..1975)
Misc Feature(13)1706..1834
Misc Feature(14)1739..1852
Misc Feature(15)1835..1966
Misc Feature(16)1871..1978
Misc Feature(17)1967..2107
Misc Feature(18)2000..2125
Misc Feature(19)2024..2386
Misc Feature(20)order(2090..2092,2102..2104,2114..2116,2216..2218,2228..2230,2237..2239,2249..2251,2354..2356,2363..2365,2372..2377,2384..2386)
Misc Feature(21)2108..2242
Misc Feature(22)2150..2254
Misc Feature(23)2243..2368
Misc Feature(24)2276..2386
Misc Feature(25)2369..2494
Misc Feature(26)2387..3250
Misc Feature(27)2423..2425
Misc Feature(28)2435..2437
Misc Feature(29)2531..2533
Misc Feature(30)2915..2917
Misc Feature(31)3071..4204
Misc Feature(32)3152..3154
Misc Feature(33)3299..3598
Misc Feature(34)3305..3307
Misc Feature(35)3317..3319
Misc Feature(36)4040..4297
Misc Feature(37)4271..4273
Misc Feature(38)4304..4375
Misc Feature(39)4304..4306
Misc Feature(40)4346..4348
Misc Feature(41)4367..4369
Misc Feature(42)4376..4378
Misc Feature(43)4505..4507
Misc Feature(44)4892..4894
Misc Feature(45)5102..5176
Misc Feature(46)5177..5347
Misc Feature(47)5348..5407
Misc Feature(48)5408..5710
Misc Feature(49)5513..5515
Misc Feature(50)5774..5776
Misc Feature(51)5780..5782
Misc Feature(52)5783..5785
Misc Feature(53)5789..5872
Misc Feature(54)5819..6034
Misc Feature(55)6104..6106
Misc Feature(56)6110..6112
Misc Feature(57)6293..6352
Misc Feature(58)6455..6457
Misc Feature(59)6470..6472
Misc Feature(60)6566..6568
Misc Feature(61)6578..6580
Misc Feature(62)6581..6583
Misc Feature(63)6587..6589
Misc Feature(64)6644..6646
Misc Feature(65)6860..7897
Misc Feature(66)6971..6973
Misc Feature(67)7001..7003
Misc Feature(68)7040..7042
Misc Feature(69)7610..7612
Misc Feature(70)7796..7798
Misc Feature(71)7898..7900
Misc Feature(72)8201..8722
Misc Feature(73)8204..8206
Misc Feature(74)8213..8215
Misc Feature(75)8228..8230
Misc Feature(76)8321..8323
Misc Feature(77)8363..8365
Misc Feature(78)8558..8560
Misc Feature(79)8600..8611
Misc Feature(80)8714..8722
Exon (1)1..67
Exon (2)68..175
Exon (3)176..328
Exon (4)329..413
Exon (5)414..615
Exon (6)616..724
Exon (7)725..838
Exon (8)839..922
Exon (9)923..1027
Exon (10)1028..1126
Exon (11)1127..1505
Exon (12)1506..1601
Exon (13)1602..1741
Exon (14)1742..1819
Exon (15)1820..1936
Exon (16)1937..2151
Exon (17)2152..10838
Translation

Target ORF information:

RefSeq Version NM_001127510.2
Organism Homo sapiens(Human)
Definition Homo sapiens APC, WNT signaling pathway regulator (APC), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127510.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16786
Clone ID Related Accession (Same CDS sequence) NM_001127510.2 , NM_000038.5
Accession Version NM_000038.5 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 8532bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product adenomatous polyposis coli protein isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA795663.1, M73548.1, AB210001.1 and CA313732.1. On Sep 17, 2010 this sequence version replaced NM_000038.4. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also contains an alternate in-frame exon compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a. Variants 2 and 3 encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.217786.1, M73548.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000029.2
CDS86..8617
Misc Feature(1)77..79
Misc Feature(2)89..91
Misc Feature(3)95..250
Misc Feature(4)404..406
Misc Feature(5)416..418
Misc Feature(6)464..706
Misc Feature(7)1016..1324
Misc Feature(8)1442..1570
Misc Feature(9)1475..1876
Misc Feature(10)1478..1609
Misc Feature(11)order(1580..1582,1592..1594,1604..1606,1700..1702,1712..1714,1721..1723,1733..1735,1844..1846,1853..1855,1862..1867,1874..1876)
Misc Feature(12)order(1580..1582,1592..1594,1604..1606,1709..1711,1721..1723,1733..1735,1841..1843,1853..1855,1865..1867)
Misc Feature(13)1598..1726
Misc Feature(14)1631..1744
Misc Feature(15)1727..1858
Misc Feature(16)1763..1870
Misc Feature(17)1859..1999
Misc Feature(18)1892..2017
Misc Feature(19)1916..2278
Misc Feature(20)order(1982..1984,1994..1996,2006..2008,2108..2110,2120..2122,2129..2131,2141..2143,2246..2248,2255..2257,2264..2269,2276..2278)
Misc Feature(21)2000..2134
Misc Feature(22)2042..2146
Misc Feature(23)2135..2260
Misc Feature(24)2168..2278
Misc Feature(25)2249..2251
Misc Feature(26)2261..2386
Misc Feature(27)2279..3142
Misc Feature(28)2315..2317
Misc Feature(29)2327..2329
Misc Feature(30)2423..2425
Misc Feature(31)2807..2809
Misc Feature(32)2963..4096
Misc Feature(33)3044..3046
Misc Feature(34)3191..3490
Misc Feature(35)3197..3199
Misc Feature(36)3209..3211
Misc Feature(37)3920..3922
Misc Feature(38)3932..4189
Misc Feature(39)4163..4165
Misc Feature(40)4196..4267
Misc Feature(41)4196..4198
Misc Feature(42)4238..4240
Misc Feature(43)4259..4261
Misc Feature(44)4259..4261
Misc Feature(45)4268..4270
Misc Feature(46)4397..4399
Misc Feature(47)4586..4588
Misc Feature(48)4592..4594
Misc Feature(49)4595..4597
Misc Feature(50)4598..4600
Misc Feature(51)4604..4606
Misc Feature(52)4613..4615
Misc Feature(53)4784..4786
Misc Feature(54)4994..5068
Misc Feature(55)5069..5239
Misc Feature(56)5240..5299
Misc Feature(57)5300..5602
Misc Feature(58)5405..5407
Misc Feature(59)5666..5668
Misc Feature(60)5666..5668
Misc Feature(61)5672..5674
Misc Feature(62)5672..5674
Misc Feature(63)5675..5677
Misc Feature(64)5675..5677
Misc Feature(65)5681..5764
Misc Feature(66)5711..5926
Misc Feature(67)5996..5998
Misc Feature(68)6002..6004
Misc Feature(69)6185..6244
Misc Feature(70)6245..6247
Misc Feature(71)6347..6349
Misc Feature(72)6362..6364
Misc Feature(73)6362..6364
Misc Feature(74)6458..6460
Misc Feature(75)6470..6472
Misc Feature(76)6473..6475
Misc Feature(77)6479..6481
Misc Feature(78)6536..6538
Misc Feature(79)6752..7789
Misc Feature(80)6863..6865
Misc Feature(81)6893..6895
Misc Feature(82)6932..6934
Misc Feature(83)7277..7279
Misc Feature(84)7502..7504
Misc Feature(85)7688..7690
Misc Feature(86)7790..7792
Misc Feature(87)8093..8614
Misc Feature(88)8096..8098
Misc Feature(89)8105..8107
Misc Feature(90)8120..8122
Misc Feature(91)8213..8215
Misc Feature(92)8255..8257
Misc Feature(93)8450..8452
Misc Feature(94)8492..8503
Misc Feature(95)8606..8614
Exon (1)1..67
Exon (2)68..220
Exon (3)221..305
Exon (4)306..507
Exon (5)508..616
Exon (6)617..730
Exon (7)731..814
Exon (8)815..919
Exon (9)920..1018
Exon (10)1019..1397
Exon (11)1398..1493
Exon (12)1494..1633
Exon (13)1634..1711
Exon (14)1712..1828
Exon (15)1829..2043
Exon (16)2044..10730
Translation

Target ORF information:

RefSeq Version NM_000038.5
Organism Homo sapiens(Human)
Definition Homo sapiens APC, WNT signaling pathway regulator (APC), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000038.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16843
Clone ID Related Accession (Same CDS sequence) NM_001127511.2
Accession Version NM_001127511.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 8478bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product adenomatous polyposis coli protein isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP230350.1, AK294544.1, AB210001.1 and CA313732.1. On Sep 14, 2010 this sequence version replaced NM_001127511.1. Transcript Variant: This variant (1) encodes the shorter isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294544.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151741, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
ATGTACGCCT CCCTGGGCTC GGGTCCGGTC GCCCCTTTGC CCGCTTCTGT ACCACCCTCA 
GTTCTCGGGT CCTGGAGCAC CGGCGGCAGC AGGAGCTGCG TCCGGCAGGA GACGAAGAGC
CCGGGCGGCG CTCGTACTTC TGGCCACTGG GCGAGCGTCT GGCAGGAAGT ACTTAAACAA
CTACAAGGAA GTATTGAAGA TGAAGCTATG GCTTCTTCTG GACAGATTGA TTTATTAGAG
CGTCTTAAAG AGCTTAACTT AGATAGCAGT AATTTCCCTG GAGTAAAACT GCGGTCAAAA
ATGTCCCTCC GTTCTTATGG AAGCCGGGAA GGATCTGTAT CAAGCCGTTC TGGAGAGTGC
AGTCCTGTTC CTATGGGTTC ATTTCCAAGA AGAGGGTTTG TAAATGGAAG CAGAGAAAGT
ACTGGATATT TAGAAGAACT TGAGAAAGAG AGGTCATTGC TTCTTGCTGA TCTTGACAAA
GAAGAAAAGG AAAAAGACTG GTATTACGCT CAACTTCAGA ATCTCACTAA AAGAATAGAT
AGTCTTCCTT TAACTGAAAA TTTTTCCTTA CAAACAGATA TGACCAGAAG GCAATTGGAA
TATGAAGCAA GGCAAATCAG AGTTGCGATG GAAGAACAAC TAGGTACCTG CCAGGATATG
GAAAAACGAG CACAGAGGTC ATCTCAGAAC AAGCATGAAA CCGGCTCACA TGATGCTGAG
CGGCAGAATG AAGGTCAAGG AGTGGGAGAA ATCAACATGG CAACTTCTGG TAATGGTCAG
GGTTCAACTA CACGAATGGA CCATGAAACA GCCAGTGTTT TGAGTTCTAG TAGCACACAC
TCTGCACCTC GAAGGCTGAC AAGTCATCTG GGAACCAAGG TGGAAATGGT GTATTCATTG
TTGTCAATGC TTGGTACTCA TGATAAGGAT GATATGTCGC GAACTTTGCT AGCTATGTCT
AGCTCCCAAG ACAGCTGTAT ATCCATGCGA CAGTCTGGAT GTCTTCCTCT CCTCATCCAG
CTTTTACATG GCAATGACAA AGACTCTGTA TTGTTGGGAA ATTCCCGGGG CAGTAAAGAG
GCTCGGGCCA GGGCCAGTGC AGCACTCCAC AACATCATTC ACTCACAGCC TGATGACAAG
AGAGGCAGGC GTGAAATCCG AGTCCTTCAT CTTTTGGAAC AGATACGCGC TTACTGTGAA
ACCTGTTGGG AGTGGCAGGA AGCTCATGAA CCAGGCATGG ACCAGGACAA AAATCCAATG
CCAGCTCCTG TTGAACATCA GATCTGTCCT GCTGTGTGTG TTCTAATGAA ACTTTCATTT
GATGAAGAGC ATAGACATGC AATGAATGAA CTAGGGGGAC TACAGGCCAT TGCAGAATTA
TTGCAAGTGG ACTGTGAAAT GTATGGGCTT ACTAATGACC ACTACAGTAT TACACTAAGA
CGATATGCTG GAATGGCTTT GACAAACTTG ACTTTTGGAG ATGTAGCCAA CAAGGCTACG
CTATGCTCTA TGAAAGGCTG CATGAGAGCA CTTGTGGCCC AACTAAAATC TGAAAGTGAA
GACTTACAGC AGGTTATTGC GAGTGTTTTG AGGAATTTGT CTTGGCGAGC AGATGTAAAT
AGTAAAAAGA CGTTGCGAGA AGTTGGAAGT GTGAAAGCAT TGATGGAATG TGCTTTAGAA
GTTAAAAAGG AATCAACCCT CAAAAGCGTA TTGAGTGCCT TATGGAATTT GTCAGCACAT
TGCACTGAGA ATAAAGCTGA TATATGTGCT GTAGATGGTG CACTTGCATT TTTGGTTGGC
ACTCTTACTT ACCGGAGCCA GACAAACACT TTAGCCATTA TTGAAAGTGG AGGTGGGATA
TTACGGAATG TGTCCAGCTT GATAGCTACA AATGAGGACC ACAGGCAAAT CCTAAGAGAG
AACAACTGTC TACAAACTTT ATTACAACAC TTAAAATCTC ATAGTTTGAC AATAGTCAGT
AATGCATGTG GAACTTTGTG GAATCTCTCA GCAAGAAATC CTAAAGACCA GGAAGCATTA
TGGGACATGG GGGCAGTTAG CATGCTCAAG AACCTCATTC ATTCAAAGCA CAAAATGATT
GCTATGGGAA GTGCTGCAGC TTTAAGGAAT CTCATGGCAA ATAGGCCTGC GAAGTACAAG
GATGCCAATA TTATGTCTCC TGGCTCAAGC TTGCCATCTC TTCATGTTAG GAAACAAAAA
GCCCTAGAAG CAGAATTAGA TGCTCAGCAC TTATCAGAAA CTTTTGACAA TATAGACAAT
TTAAGTCCCA AGGCATCTCA TCGTAGTAAG CAGAGACACA AGCAAAGTCT CTATGGTGAT
TATGTTTTTG ACACCAATCG ACATGATGAT AATAGGTCAG ACAATTTTAA TACTGGCAAC
ATGACTGTCC TTTCACCATA TTTGAATACT ACAGTGTTAC CCAGCTCCTC TTCATCAAGA
GGAAGCTTAG ATAGTTCTCG TTCTGAAAAA GATAGAAGTT TGGAGAGAGA ACGCGGAATT
GGTCTAGGCA ACTACCATCC AGCAACAGAA AATCCAGGAA CTTCTTCAAA GCGAGGTTTG
CAGATCTCCA CCACTGCAGC CCAGATTGCC AAAGTCATGG AAGAAGTGTC AGCCATTCAT
ACCTCTCAGG AAGACAGAAG TTCTGGGTCT ACCACTGAAT TACATTGTGT GACAGATGAG
AGAAATGCAC TTAGAAGAAG CTCTGCTGCC CATACACATT CAAACACTTA CAATTTCACT
AAGTCGGAAA ATTCAAATAG GACATGTTCT ATGCCTTATG CCAAATTAGA ATACAAGAGA
TCTTCAAATG ATAGTTTAAA TAGTGTCAGT AGTAGTGATG GTTATGGTAA AAGAGGTCAA
ATGAAACCCT CGATTGAATC CTATTCTGAA GATGATGAAA GTAAGTTTTG CAGTTATGGT
CAATACCCAG CCGACCTAGC CCATAAAATA CATAGTGCAA ATCATATGGA TGATAATGAT
GGAGAACTAG ATACACCAAT AAATTATAGT CTTAAATATT CAGATGAGCA GTTGAACTCT
GGAAGGCAAA GTCCTTCACA GAATGAAAGA TGGGCAAGAC CCAAACACAT AATAGAAGAT
GAAATAAAAC AAAGTGAGCA AAGACAATCA AGGAATCAAA GTACAACTTA TCCTGTTTAT
ACTGAGAGCA CTGATGATAA ACACCTCAAG TTCCAACCAC ATTTTGGACA GCAGGAATGT
GTTTCTCCAT ACAGGTCACG GGGAGCCAAT GGTTCAGAAA CAAATCGAGT GGGTTCTAAT
CATGGAATTA ATCAAAATGT AAGCCAGTCT TTGTGTCAAG AAGATGACTA TGAAGATGAT
AAGCCTACCA ATTATAGTGA ACGTTACTCT GAAGAAGAAC AGCATGAAGA AGAAGAGAGA
CCAACAAATT ATAGCATAAA ATATAATGAA GAGAAACGTC ATGTGGATCA GCCTATTGAT
TATAGTTTAA AATATGCCAC AGATATTCCT TCATCACAGA AACAGTCATT TTCATTCTCA
AAGAGTTCAT CTGGACAAAG CAGTAAAACC GAACATATGT CTTCAAGCAG TGAGAATACG
TCCACACCTT CATCTAATGC CAAGAGGCAG AATCAGCTCC ATCCAAGTTC TGCACAGAGT
AGAAGTGGTC AGCCTCAAAA GGCTGCCACT TGCAAAGTTT CTTCTATTAA CCAAGAAACA
ATACAGACTT ATTGTGTAGA AGATACTCCA ATATGTTTTT CAAGATGTAG TTCATTATCA
TCTTTGTCAT CAGCTGAAGA TGAAATAGGA TGTAATCAGA CGACACAGGA AGCAGATTCT
GCTAATACCC TGCAAATAGC AGAAATAAAA GAAAAGATTG GAACTAGGTC AGCTGAAGAT
CCTGTGAGCG AAGTTCCAGC AGTGTCACAG CACCCTAGAA CCAAATCCAG CAGACTGCAG
GGTTCTAGTT TATCTTCAGA ATCAGCCAGG CACAAAGCTG TTGAATTTTC TTCAGGAGCG
AAATCTCCCT CCAAAAGTGG TGCTCAGACA CCCAAAAGTC CACCTGAACA CTATGTTCAG
GAGACCCCAC TCATGTTTAG CAGATGTACT TCTGTCAGTT CACTTGATAG TTTTGAGAGT
CGTTCGATTG CCAGCTCCGT TCAGAGTGAA CCATGCAGTG GAATGGTAAG TGGCATTATA
AGCCCCAGTG ATCTTCCAGA TAGCCCTGGA CAAACCATGC CACCAAGCAG AAGTAAAACA
CCTCCACCAC CTCCTCAAAC AGCTCAAACC AAGCGAGAAG TACCTAAAAA TAAAGCACCT
ACTGCTGAAA AGAGAGAGAG TGGACCTAAG CAAGCTGCAG TAAATGCTGC AGTTCAGAGG
GTCCAGGTTC TTCCAGATGC TGATACTTTA TTACATTTTG CCACGGAAAG TACTCCAGAT
GGATTTTCTT GTTCATCCAG CCTGAGTGCT CTGAGCCTCG ATGAGCCATT TATACAGAAA
GATGTGGAAT TAAGAATAAT GCCTCCAGTT CAGGAAAATG ACAATGGGAA TGAAACAGAA
TCAGAGCAGC CTAAAGAATC AAATGAAAAC CAAGAGAAAG AGGCAGAAAA AACTATTGAT
TCTGAAAAGG ACCTATTAGA TGATTCAGAT GATGATGATA TTGAAATACT AGAAGAATGT
ATTATTTCTG CCATGCCAAC AAAGTCATCA CGTAAAGCAA AAAAGCCAGC CCAGACTGCT
TCAAAATTAC CTCCACCTGT GGCAAGGAAA CCAAGTCAGC TGCCTGTGTA CAAACTTCTA
CCATCACAAA ACAGGTTGCA ACCCCAAAAG CATGTTAGTT TTACACCGGG GGATGATATG
CCACGGGTGT ATTGTGTTGA AGGGACACCT ATAAACTTTT CCACAGCTAC ATCTCTAAGT
GATCTAACAA TCGAATCCCC TCCAAATGAG TTAGCTGCTG GAGAAGGAGT TAGAGGAGGG
GCACAGTCAG GTGAATTTGA AAAACGAGAT ACCATTCCTA CAGAAGGCAG AAGTACAGAT
GAGGCTCAAG GAGGAAAAAC CTCATCTGTA ACCATACCTG AATTGGATGA CAATAAAGCA
GAGGAAGGTG ATATTCTTGC AGAATGCATT AATTCTGCTA TGCCCAAAGG GAAAAGTCAC
AAGCCTTTCC GTGTGAAAAA GATAATGGAC CAGGTCCAGC AAGCATCTGC GTCTTCTTCT
GCACCCAACA AAAATCAGTT AGATGGTAAG AAAAAGAAAC CAACTTCACC AGTAAAACCT
ATACCACAAA ATACTGAATA TAGGACACGT GTAAGAAAAA ATGCAGACTC AAAAAATAAT
TTAAATGCTG AGAGAGTTTT CTCAGACAAC AAAGATTCAA AGAAACAGAA TTTGAAAAAT
AATTCCAAGG TCTTCAATGA TAAGCTCCCA AATAATGAAG ATAGAGTCAG AGGAAGTTTT
GCTTTTGATT CACCTCATCA TTACACGCCT ATTGAAGGAA CTCCTTACTG TTTTTCACGA
AATGATTCTT TGAGTTCTCT AGATTTTGAT GATGATGATG TTGACCTTTC CAGGGAAAAG
GCTGAATTAA GAAAGGCAAA AGAAAATAAG GAATCAGAGG CTAAAGTTAC CAGCCACACA
GAACTAACCT CCAACCAACA ATCAGCTAAT AAGACACAAG CTATTGCAAA GCAGCCAATA
AATCGAGGTC AGCCTAAACC CATACTTCAG AAACAATCCA CTTTTCCCCA GTCATCCAAA
GACATACCAG ACAGAGGGGC AGCAACTGAT GAAAAGTTAC AGAATTTTGC TATTGAAAAT
ACTCCGGTTT GCTTTTCTCA TAATTCCTCT CTGAGTTCTC TCAGTGACAT TGACCAAGAA
AACAACAATA AAGAAAATGA ACCTATCAAA GAGACTGAGC CCCCTGACTC ACAGGGAGAA
CCAAGTAAAC CTCAAGCATC AGGCTATGCT CCTAAATCAT TTCATGTTGA AGATACCCCA
GTTTGTTTCT CAAGAAACAG TTCTCTCAGT TCTCTTAGTA TTGACTCTGA AGATGACCTG
TTGCAGGAAT GTATAAGCTC CGCAATGCCA AAAAAGAAAA AGCCTTCAAG ACTCAAGGGT
GATAATGAAA AACATAGTCC CAGAAATATG GGTGGCATAT TAGGTGAAGA TCTGACACTT
GATTTGAAAG ATATACAGAG ACCAGATTCA GAACATGGTC TATCCCCTGA TTCAGAAAAT
TTTGATTGGA AAGCTATTCA GGAAGGTGCA AATTCCATAG TAAGTAGTTT ACATCAAGCT
GCTGCTGCTG CATGTTTATC TAGACAAGCT TCGTCTGATT CAGATTCCAT CCTTTCCCTG
AAATCAGGAA TCTCTCTGGG ATCACCATTT CATCTTACAC CTGATCAAGA AGAAAAACCC
TTTACAAGTA ATAAAGGCCC ACGAATTCTA AAACCAGGGG AGAAAAGTAC ATTGGAAACT
AAAAAGATAG AATCTGAAAG TAAAGGAATC AAAGGAGGAA AAAAAGTTTA TAAAAGTTTG
ATTACTGGAA AAGTTCGATC TAATTCAGAA ATTTCAGGCC AAATGAAACA GCCCCTTCAA
GCAAACATGC CTTCAATCTC TCGAGGCAGG ACAATGATTC ATATTCCAGG AGTTCGAAAT
AGCTCCTCAA GTACAAGTCC TGTTTCTAAA AAAGGCCCAC CCCTTAAGAC TCCAGCCTCC
AAAAGCCCTA GTGAAGGTCA AACAGCCACC ACTTCTCCTA GAGGAGCCAA GCCATCTGTG
AAATCAGAAT TAAGCCCTGT TGCCAGGCAG ACATCCCAAA TAGGTGGGTC AAGTAAAGCA
CCTTCTAGAT CAGGATCTAG AGATTCGACC CCTTCAAGAC CTGCCCAGCA ACCATTAAGT
AGACCTATAC AGTCTCCTGG CCGAAACTCA ATTTCCCCTG GTAGAAATGG AATAAGTCCT
CCTAACAAAT TATCTCAACT TCCAAGGACA TCATCCCCTA GTACTGCTTC AACTAAGTCC
TCAGGTTCTG GAAAAATGTC ATATACATCT CCAGGTAGAC AGATGAGCCA ACAGAACCTT
ACCAAACAAA CAGGTTTATC CAAGAATGCC AGTAGTATTC CAAGAAGTGA GTCTGCCTCC
AAAGGACTAA ATCAGATGAA TAATGGTAAT GGAGCCAATA AAAAGGTAGA ACTTTCTAGA
ATGTCTTCAA CTAAATCAAG TGGAAGTGAA TCTGATAGAT CAGAAAGACC TGTATTAGTA
CGCCAGTCAA CTTTCATCAA AGAAGCTCCA AGCCCAACCT TAAGAAGAAA ATTGGAGGAA
TCTGCTTCAT TTGAATCTCT TTCTCCATCA TCTAGACCAG CTTCTCCCAC TAGGTCCCAG
GCACAAACTC CAGTTTTAAG TCCTTCCCTT CCTGATATGT CTCTATCCAC ACATTCGTCT
GTTCAGGCTG GTGGATGGCG AAAACTCCCA CCTAATCTCA GTCCCACTAT AGAGTATAAT
GATGGAAGAC CAGCAAAGCG CCATGATATT GCACGGTCTC ATTCTGAAAG TCCTTCTAGA
CTTCCAATCA ATAGGTCAGG AACCTGGAAA CGTGAGCACA GCAAACATTC ATCATCCCTT
CCTCGAGTAA GCACTTGGAG AAGAACTGGA AGTTCATCTT CAATTCTTTC TGCTTCATCA
GAATCCAGTG AAAAAGCAAA AAGTGAGGAT GAAAAACATG TGAACTCTAT TTCAGGAACC
AAACAAAGTA AAGAAAACCA AGTATCCGCA AAAGGAACAT GGAGAAAAAT AAAAGAAAAT
GAATTTTCTC CCACAAATAG TACTTCTCAG ACCGTTTCCT CAGGTGCTAC AAATGGTGCT
GAATCAAAGA CTCTAATTTA TCAAATGGCA CCTGCTGTTT CTAAAACAGA GGATGTTTGG
GTGAGAATTG AGGACTGTCC CATTAACAAT CCTAGATCTG GAAGATCTCC CACAGGTAAT
ACTCCCCCGG TGATTGACAG TGTTTCAGAA AAGGCAAATC CAAACATTAA AGATTCAAAA
GATAATCAGG CAAAACAAAA TGTGGGTAAT GGCAGTGTTC CCATGCGTAC CGTGGGTTTG
GAAAATCGCC TGAACTCCTT TATTCAGGTG GATGCCCCTG ACCAAAAAGG AACTGAGATA
AAACCAGGAC AAAATAATCC TGTCCCTGTA TCAGAGACTA ATGAAAGTTC TATAGTGGAA
CGTACCCCAT TCAGTTCTAG CAGCTCAAGC AAACACAGTT CACCTAGTGG GACTGTTGCT
GCCAGAGTGA CTCCTTTTAA TTACAACCCA AGCCCTAGGA AAAGCAGCGC AGATAGCACT
TCAGCTCGGC CATCTCAGAT CCCAACTCCA GTGAATAACA ACACAAAGAA GCGAGATTCC
AAAACTGACA GCACAGAATC CAGTGGAACC CAAAGTCCTA AGCGCCATTC TGGGTCTTAC
CTTGTGACAT CTGTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001120983.2
CDS214..8691
Misc Feature(1)175..177
Misc Feature(2)622..864
Misc Feature(3)1090..1398
Misc Feature(4)1549..1950
Misc Feature(5)1552..1683
Misc Feature(6)order(1654..1656,1666..1668,1678..1680,1774..1776,1786..1788,1795..1797,1807..1809,1918..1920,1927..1929,1936..1941,1948..1950)
Misc Feature(7)order(1654..1656,1666..1668,1678..1680,1783..1785,1795..1797,1807..1809,1915..1917,1927..1929,1939..1941)
Misc Feature(8)1705..1818
Misc Feature(9)1837..1944
Misc Feature(10)1966..2091
Misc Feature(11)1990..2352
Misc Feature(12)order(2056..2058,2068..2070,2080..2082,2182..2184,2194..2196,2203..2205,2215..2217,2320..2322,2329..2331,2338..2343,2350..2352)
Misc Feature(13)2116..2220
Misc Feature(14)2242..2352
Misc Feature(15)2353..3216
Misc Feature(16)3265..3564
Misc Feature(17)4006..4263
Misc Feature(18)5068..5142
Misc Feature(19)5143..5313
Misc Feature(20)5314..5373
Misc Feature(21)5374..5676
Misc Feature(22)5785..6000
Misc Feature(23)6259..6318
Misc Feature(24)6826..7863
Misc Feature(25)8167..8688
Exon (1)1..378
Exon (2)379..463
Exon (3)464..665
Exon (4)666..774
Exon (5)775..888
Exon (6)889..993
Exon (7)994..1092
Exon (8)1093..1471
Exon (9)1472..1567
Exon (10)1568..1707
Exon (11)1708..1785
Exon (12)1786..1902
Exon (13)1903..2117
Exon (14)2118..10804
Translation

Target ORF information:

RefSeq Version NM_001127511.2
Organism Homo sapiens(Human)
Definition Homo sapiens APC, WNT signaling pathway regulator (APC), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127511.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
ATGTACGCCT CCCTGGGCTC GGGTCCGGTC GCCCCTTTGC CCGCTTCTGT ACCACCCTCA 
GTTCTCGGGT CCTGGAGCAC CGGCGGCAGC AGGAGCTGCG TCCGGCAGGA GACGAAGAGC
CCGGGCGGCG CTCGTACTTC TGGCCACTGG GCGAGCGTCT GGCAGGAAGT ACTTAAACAA
CTACAAGGAA GTATTGAAGA TGAAGCTATG GCTTCTTCTG GACAGATTGA TTTATTAGAG
CGTCTTAAAG AGCTTAACTT AGATAGCAGT AATTTCCCTG GAGTAAAACT GCGGTCAAAA
ATGTCCCTCC GTTCTTATGG AAGCCGGGAA GGATCTGTAT CAAGCCGTTC TGGAGAGTGC
AGTCCTGTTC CTATGGGTTC ATTTCCAAGA AGAGGGTTTG TAAATGGAAG CAGAGAAAGT
ACTGGATATT TAGAAGAACT TGAGAAAGAG AGGTCATTGC TTCTTGCTGA TCTTGACAAA
GAAGAAAAGG AAAAAGACTG GTATTACGCT CAACTTCAGA ATCTCACTAA AAGAATAGAT
AGTCTTCCTT TAACTGAAAA TTTTTCCTTA CAAACAGATA TGACCAGAAG GCAATTGGAA
TATGAAGCAA GGCAAATCAG AGTTGCGATG GAAGAACAAC TAGGTACCTG CCAGGATATG
GAAAAACGAG CACAGAGGTC ATCTCAGAAC AAGCATGAAA CCGGCTCACA TGATGCTGAG
CGGCAGAATG AAGGTCAAGG AGTGGGAGAA ATCAACATGG CAACTTCTGG TAATGGTCAG
GGTTCAACTA CACGAATGGA CCATGAAACA GCCAGTGTTT TGAGTTCTAG TAGCACACAC
TCTGCACCTC GAAGGCTGAC AAGTCATCTG GGAACCAAGG TGGAAATGGT GTATTCATTG
TTGTCAATGC TTGGTACTCA TGATAAGGAT GATATGTCGC GAACTTTGCT AGCTATGTCT
AGCTCCCAAG ACAGCTGTAT ATCCATGCGA CAGTCTGGAT GTCTTCCTCT CCTCATCCAG
CTTTTACATG GCAATGACAA AGACTCTGTA TTGTTGGGAA ATTCCCGGGG CAGTAAAGAG
GCTCGGGCCA GGGCCAGTGC AGCACTCCAC AACATCATTC ACTCACAGCC TGATGACAAG
AGAGGCAGGC GTGAAATCCG AGTCCTTCAT CTTTTGGAAC AGATACGCGC TTACTGTGAA
ACCTGTTGGG AGTGGCAGGA AGCTCATGAA CCAGGCATGG ACCAGGACAA AAATCCAATG
CCAGCTCCTG TTGAACATCA GATCTGTCCT GCTGTGTGTG TTCTAATGAA ACTTTCATTT
GATGAAGAGC ATAGACATGC AATGAATGAA CTAGGGGGAC TACAGGCCAT TGCAGAATTA
TTGCAAGTGG ACTGTGAAAT GTATGGGCTT ACTAATGACC ACTACAGTAT TACACTAAGA
CGATATGCTG GAATGGCTTT GACAAACTTG ACTTTTGGAG ATGTAGCCAA CAAGGCTACG
CTATGCTCTA TGAAAGGCTG CATGAGAGCA CTTGTGGCCC AACTAAAATC TGAAAGTGAA
GACTTACAGC AGGTTATTGC GAGTGTTTTG AGGAATTTGT CTTGGCGAGC AGATGTAAAT
AGTAAAAAGA CGTTGCGAGA AGTTGGAAGT GTGAAAGCAT TGATGGAATG TGCTTTAGAA
GTTAAAAAGG AATCAACCCT CAAAAGCGTA TTGAGTGCCT TATGGAATTT GTCAGCACAT
TGCACTGAGA ATAAAGCTGA TATATGTGCT GTAGATGGTG CACTTGCATT TTTGGTTGGC
ACTCTTACTT ACCGGAGCCA GACAAACACT TTAGCCATTA TTGAAAGTGG AGGTGGGATA
TTACGGAATG TGTCCAGCTT GATAGCTACA AATGAGGACC ACAGGCAAAT CCTAAGAGAG
AACAACTGTC TACAAACTTT ATTACAACAC TTAAAATCTC ATAGTTTGAC AATAGTCAGT
AATGCATGTG GAACTTTGTG GAATCTCTCA GCAAGAAATC CTAAAGACCA GGAAGCATTA
TGGGACATGG GGGCAGTTAG CATGCTCAAG AACCTCATTC ATTCAAAGCA CAAAATGATT
GCTATGGGAA GTGCTGCAGC TTTAAGGAAT CTCATGGCAA ATAGGCCTGC GAAGTACAAG
GATGCCAATA TTATGTCTCC TGGCTCAAGC TTGCCATCTC TTCATGTTAG GAAACAAAAA
GCCCTAGAAG CAGAATTAGA TGCTCAGCAC TTATCAGAAA CTTTTGACAA TATAGACAAT
TTAAGTCCCA AGGCATCTCA TCGTAGTAAG CAGAGACACA AGCAAAGTCT CTATGGTGAT
TATGTTTTTG ACACCAATCG ACATGATGAT AATAGGTCAG ACAATTTTAA TACTGGCAAC
ATGACTGTCC TTTCACCATA TTTGAATACT ACAGTGTTAC CCAGCTCCTC TTCATCAAGA
GGAAGCTTAG ATAGTTCTCG TTCTGAAAAA GATAGAAGTT TGGAGAGAGA ACGCGGAATT
GGTCTAGGCA ACTACCATCC AGCAACAGAA AATCCAGGAA CTTCTTCAAA GCGAGGTTTG
CAGATCTCCA CCACTGCAGC CCAGATTGCC AAAGTCATGG AAGAAGTGTC AGCCATTCAT
ACCTCTCAGG AAGACAGAAG TTCTGGGTCT ACCACTGAAT TACATTGTGT GACAGATGAG
AGAAATGCAC TTAGAAGAAG CTCTGCTGCC CATACACATT CAAACACTTA CAATTTCACT
AAGTCGGAAA ATTCAAATAG GACATGTTCT ATGCCTTATG CCAAATTAGA ATACAAGAGA
TCTTCAAATG ATAGTTTAAA TAGTGTCAGT AGTAGTGATG GTTATGGTAA AAGAGGTCAA
ATGAAACCCT CGATTGAATC CTATTCTGAA GATGATGAAA GTAAGTTTTG CAGTTATGGT
CAATACCCAG CCGACCTAGC CCATAAAATA CATAGTGCAA ATCATATGGA TGATAATGAT
GGAGAACTAG ATACACCAAT AAATTATAGT CTTAAATATT CAGATGAGCA GTTGAACTCT
GGAAGGCAAA GTCCTTCACA GAATGAAAGA TGGGCAAGAC CCAAACACAT AATAGAAGAT
GAAATAAAAC AAAGTGAGCA AAGACAATCA AGGAATCAAA GTACAACTTA TCCTGTTTAT
ACTGAGAGCA CTGATGATAA ACACCTCAAG TTCCAACCAC ATTTTGGACA GCAGGAATGT
GTTTCTCCAT ACAGGTCACG GGGAGCCAAT GGTTCAGAAA CAAATCGAGT GGGTTCTAAT
CATGGAATTA ATCAAAATGT AAGCCAGTCT TTGTGTCAAG AAGATGACTA TGAAGATGAT
AAGCCTACCA ATTATAGTGA ACGTTACTCT GAAGAAGAAC AGCATGAAGA AGAAGAGAGA
CCAACAAATT ATAGCATAAA ATATAATGAA GAGAAACGTC ATGTGGATCA GCCTATTGAT
TATAGTTTAA AATATGCCAC AGATATTCCT TCATCACAGA AACAGTCATT TTCATTCTCA
AAGAGTTCAT CTGGACAAAG CAGTAAAACC GAACATATGT CTTCAAGCAG TGAGAATACG
TCCACACCTT CATCTAATGC CAAGAGGCAG AATCAGCTCC ATCCAAGTTC TGCACAGAGT
AGAAGTGGTC AGCCTCAAAA GGCTGCCACT TGCAAAGTTT CTTCTATTAA CCAAGAAACA
ATACAGACTT ATTGTGTAGA AGATACTCCA ATATGTTTTT CAAGATGTAG TTCATTATCA
TCTTTGTCAT CAGCTGAAGA TGAAATAGGA TGTAATCAGA CGACACAGGA AGCAGATTCT
GCTAATACCC TGCAAATAGC AGAAATAAAA GAAAAGATTG GAACTAGGTC AGCTGAAGAT
CCTGTGAGCG AAGTTCCAGC AGTGTCACAG CACCCTAGAA CCAAATCCAG CAGACTGCAG
GGTTCTAGTT TATCTTCAGA ATCAGCCAGG CACAAAGCTG TTGAATTTTC TTCAGGAGCG
AAATCTCCCT CCAAAAGTGG TGCTCAGACA CCCAAAAGTC CACCTGAACA CTATGTTCAG
GAGACCCCAC TCATGTTTAG CAGATGTACT TCTGTCAGTT CACTTGATAG TTTTGAGAGT
CGTTCGATTG CCAGCTCCGT TCAGAGTGAA CCATGCAGTG GAATGGTAAG TGGCATTATA
AGCCCCAGTG ATCTTCCAGA TAGCCCTGGA CAAACCATGC CACCAAGCAG AAGTAAAACA
CCTCCACCAC CTCCTCAAAC AGCTCAAACC AAGCGAGAAG TACCTAAAAA TAAAGCACCT
ACTGCTGAAA AGAGAGAGAG TGGACCTAAG CAAGCTGCAG TAAATGCTGC AGTTCAGAGG
GTCCAGGTTC TTCCAGATGC TGATACTTTA TTACATTTTG CCACGGAAAG TACTCCAGAT
GGATTTTCTT GTTCATCCAG CCTGAGTGCT CTGAGCCTCG ATGAGCCATT TATACAGAAA
GATGTGGAAT TAAGAATAAT GCCTCCAGTT CAGGAAAATG ACAATGGGAA TGAAACAGAA
TCAGAGCAGC CTAAAGAATC AAATGAAAAC CAAGAGAAAG AGGCAGAAAA AACTATTGAT
TCTGAAAAGG ACCTATTAGA TGATTCAGAT GATGATGATA TTGAAATACT AGAAGAATGT
ATTATTTCTG CCATGCCAAC AAAGTCATCA CGTAAAGCAA AAAAGCCAGC CCAGACTGCT
TCAAAATTAC CTCCACCTGT GGCAAGGAAA CCAAGTCAGC TGCCTGTGTA CAAACTTCTA
CCATCACAAA ACAGGTTGCA ACCCCAAAAG CATGTTAGTT TTACACCGGG GGATGATATG
CCACGGGTGT ATTGTGTTGA AGGGACACCT ATAAACTTTT CCACAGCTAC ATCTCTAAGT
GATCTAACAA TCGAATCCCC TCCAAATGAG TTAGCTGCTG GAGAAGGAGT TAGAGGAGGG
GCACAGTCAG GTGAATTTGA AAAACGAGAT ACCATTCCTA CAGAAGGCAG AAGTACAGAT
GAGGCTCAAG GAGGAAAAAC CTCATCTGTA ACCATACCTG AATTGGATGA CAATAAAGCA
GAGGAAGGTG ATATTCTTGC AGAATGCATT AATTCTGCTA TGCCCAAAGG GAAAAGTCAC
AAGCCTTTCC GTGTGAAAAA GATAATGGAC CAGGTCCAGC AAGCATCTGC GTCTTCTTCT
GCACCCAACA AAAATCAGTT AGATGGTAAG AAAAAGAAAC CAACTTCACC AGTAAAACCT
ATACCACAAA ATACTGAATA TAGGACACGT GTAAGAAAAA ATGCAGACTC AAAAAATAAT
TTAAATGCTG AGAGAGTTTT CTCAGACAAC AAAGATTCAA AGAAACAGAA TTTGAAAAAT
AATTCCAAGG TCTTCAATGA TAAGCTCCCA AATAATGAAG ATAGAGTCAG AGGAAGTTTT
GCTTTTGATT CACCTCATCA TTACACGCCT ATTGAAGGAA CTCCTTACTG TTTTTCACGA
AATGATTCTT TGAGTTCTCT AGATTTTGAT GATGATGATG TTGACCTTTC CAGGGAAAAG
GCTGAATTAA GAAAGGCAAA AGAAAATAAG GAATCAGAGG CTAAAGTTAC CAGCCACACA
GAACTAACCT CCAACCAACA ATCAGCTAAT AAGACACAAG CTATTGCAAA GCAGCCAATA
AATCGAGGTC AGCCTAAACC CATACTTCAG AAACAATCCA CTTTTCCCCA GTCATCCAAA
GACATACCAG ACAGAGGGGC AGCAACTGAT GAAAAGTTAC AGAATTTTGC TATTGAAAAT
ACTCCGGTTT GCTTTTCTCA TAATTCCTCT CTGAGTTCTC TCAGTGACAT TGACCAAGAA
AACAACAATA AAGAAAATGA ACCTATCAAA GAGACTGAGC CCCCTGACTC ACAGGGAGAA
CCAAGTAAAC CTCAAGCATC AGGCTATGCT CCTAAATCAT TTCATGTTGA AGATACCCCA
GTTTGTTTCT CAAGAAACAG TTCTCTCAGT TCTCTTAGTA TTGACTCTGA AGATGACCTG
TTGCAGGAAT GTATAAGCTC CGCAATGCCA AAAAAGAAAA AGCCTTCAAG ACTCAAGGGT
GATAATGAAA AACATAGTCC CAGAAATATG GGTGGCATAT TAGGTGAAGA TCTGACACTT
GATTTGAAAG ATATACAGAG ACCAGATTCA GAACATGGTC TATCCCCTGA TTCAGAAAAT
TTTGATTGGA AAGCTATTCA GGAAGGTGCA AATTCCATAG TAAGTAGTTT ACATCAAGCT
GCTGCTGCTG CATGTTTATC TAGACAAGCT TCGTCTGATT CAGATTCCAT CCTTTCCCTG
AAATCAGGAA TCTCTCTGGG ATCACCATTT CATCTTACAC CTGATCAAGA AGAAAAACCC
TTTACAAGTA ATAAAGGCCC ACGAATTCTA AAACCAGGGG AGAAAAGTAC ATTGGAAACT
AAAAAGATAG AATCTGAAAG TAAAGGAATC AAAGGAGGAA AAAAAGTTTA TAAAAGTTTG
ATTACTGGAA AAGTTCGATC TAATTCAGAA ATTTCAGGCC AAATGAAACA GCCCCTTCAA
GCAAACATGC CTTCAATCTC TCGAGGCAGG ACAATGATTC ATATTCCAGG AGTTCGAAAT
AGCTCCTCAA GTACAAGTCC TGTTTCTAAA AAAGGCCCAC CCCTTAAGAC TCCAGCCTCC
AAAAGCCCTA GTGAAGGTCA AACAGCCACC ACTTCTCCTA GAGGAGCCAA GCCATCTGTG
AAATCAGAAT TAAGCCCTGT TGCCAGGCAG ACATCCCAAA TAGGTGGGTC AAGTAAAGCA
CCTTCTAGAT CAGGATCTAG AGATTCGACC CCTTCAAGAC CTGCCCAGCA ACCATTAAGT
AGACCTATAC AGTCTCCTGG CCGAAACTCA ATTTCCCCTG GTAGAAATGG AATAAGTCCT
CCTAACAAAT TATCTCAACT TCCAAGGACA TCATCCCCTA GTACTGCTTC AACTAAGTCC
TCAGGTTCTG GAAAAATGTC ATATACATCT CCAGGTAGAC AGATGAGCCA ACAGAACCTT
ACCAAACAAA CAGGTTTATC CAAGAATGCC AGTAGTATTC CAAGAAGTGA GTCTGCCTCC
AAAGGACTAA ATCAGATGAA TAATGGTAAT GGAGCCAATA AAAAGGTAGA ACTTTCTAGA
ATGTCTTCAA CTAAATCAAG TGGAAGTGAA TCTGATAGAT CAGAAAGACC TGTATTAGTA
CGCCAGTCAA CTTTCATCAA AGAAGCTCCA AGCCCAACCT TAAGAAGAAA ATTGGAGGAA
TCTGCTTCAT TTGAATCTCT TTCTCCATCA TCTAGACCAG CTTCTCCCAC TAGGTCCCAG
GCACAAACTC CAGTTTTAAG TCCTTCCCTT CCTGATATGT CTCTATCCAC ACATTCGTCT
GTTCAGGCTG GTGGATGGCG AAAACTCCCA CCTAATCTCA GTCCCACTAT AGAGTATAAT
GATGGAAGAC CAGCAAAGCG CCATGATATT GCACGGTCTC ATTCTGAAAG TCCTTCTAGA
CTTCCAATCA ATAGGTCAGG AACCTGGAAA CGTGAGCACA GCAAACATTC ATCATCCCTT
CCTCGAGTAA GCACTTGGAG AAGAACTGGA AGTTCATCTT CAATTCTTTC TGCTTCATCA
GAATCCAGTG AAAAAGCAAA AAGTGAGGAT GAAAAACATG TGAACTCTAT TTCAGGAACC
AAACAAAGTA AAGAAAACCA AGTATCCGCA AAAGGAACAT GGAGAAAAAT AAAAGAAAAT
GAATTTTCTC CCACAAATAG TACTTCTCAG ACCGTTTCCT CAGGTGCTAC AAATGGTGCT
GAATCAAAGA CTCTAATTTA TCAAATGGCA CCTGCTGTTT CTAAAACAGA GGATGTTTGG
GTGAGAATTG AGGACTGTCC CATTAACAAT CCTAGATCTG GAAGATCTCC CACAGGTAAT
ACTCCCCCGG TGATTGACAG TGTTTCAGAA AAGGCAAATC CAAACATTAA AGATTCAAAA
GATAATCAGG CAAAACAAAA TGTGGGTAAT GGCAGTGTTC CCATGCGTAC CGTGGGTTTG
GAAAATCGCC TGAACTCCTT TATTCAGGTG GATGCCCCTG ACCAAAAAGG AACTGAGATA
AAACCAGGAC AAAATAATCC TGTCCCTGTA TCAGAGACTA ATGAAAGTTC TATAGTGGAA
CGTACCCCAT TCAGTTCTAG CAGCTCAAGC AAACACAGTT CACCTAGTGG GACTGTTGCT
GCCAGAGTGA CTCCTTTTAA TTACAACCCA AGCCCTAGGA AAAGCAGCGC AGATAGCACT
TCAGCTCGGC CATCTCAGAT CCCAACTCCA GTGAATAACA ACACAAAGAA GCGAGATTCC
AAAACTGACA GCACAGAATC CAGTGGAACC CAAAGTCCTA AGCGCCATTC TGGGTCTTAC
CTTGTGACAT CTGTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer.
Journal of the National Cancer Institute109(8)(2017 08)
Zhang L,Shay JW


book

Molecular clonality analysis of esophageal adenocarcinoma by multiregion sequencing of tumor samples.
BMC research notes10(1)144(2017 Apr)
van Nistelrooij AM,van Marion R,Koppert LB,Biermann K,Spaander MC,Tilanus HW,van Lanschot JJ,Wijnhoven BP,Dinjens WN


book

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Molecular biology of the cell28(5)587-599(2017 Mar)
Gao FJ,Shi L,Hines T,Hebbar S,Neufeld KL,Smith DS


book

Identification of an alternative 5' untranslated region of the adenomatous polyposis coli gene.
Human genetics90(6)650-2(1993 Feb)
Lambertz S,Ballhausen WG


 
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